The kidneys are paired organs located retroperitoneally against the posterior abdominal wall. Each kidney filters blood to remove waste and regulate fluid and electrolyte balance, producing urine which drains via ureters into the urinary bladder, a muscular organ in the pelvis. The bladder stores urine then empties via the urethra, a muscular tube running through the pelvis to exit the body.
Nephron (The Guyton and Hall physiology)Maryam Fida
Structural and Functional unit of kidney is called nephron.
There are about 1.3 million nephron in each kidney.
New nephrons can not be regenerated by kidneys.
Functioning nephrons decrease about 10 % every 10 years at the age of 40.
At the age of 80, there are 40 % of functioning nephrons as compared to 40 yrs.
It is formed by two parts.
1. GLOMERULUS
2. BOWMAN’S CAPSULE
1- Glomerulus:
It consists of tuft of glomerular capillaries.
There is anastomosing & branching network of glomerular capillaries.
Glomerular capillaries have high hydrostatic pressure (nearly 60 mm Hg) as compared with other capillaries.
Glomerulus is surrounded by a membranous cover called Bowman’s capsule.
Each glomerulus is about 0.2 mm in diameter.
Glomerulus and Bowman’s capsule together constitute renal corpuscle.
Each renal tubule is divided into various part as they have different functions.
i- Proximal convulated tubule.
It is continuation of Bowman’s capsule.
ii- Loop of Henle. It is continuation of prox. conv. tubule.
* Loop of Henle has three parts.
a- descending limb,
b- u turn or bend in medulla and
c- ascending limb.
Ascending limb has initial thin segment followed by thick segment.
At the end of thick ascending limb, there is short segment called macula densa, which plays important role in controlling functions of nephron.
Nephron (The Guyton and Hall physiology)Maryam Fida
Structural and Functional unit of kidney is called nephron.
There are about 1.3 million nephron in each kidney.
New nephrons can not be regenerated by kidneys.
Functioning nephrons decrease about 10 % every 10 years at the age of 40.
At the age of 80, there are 40 % of functioning nephrons as compared to 40 yrs.
It is formed by two parts.
1. GLOMERULUS
2. BOWMAN’S CAPSULE
1- Glomerulus:
It consists of tuft of glomerular capillaries.
There is anastomosing & branching network of glomerular capillaries.
Glomerular capillaries have high hydrostatic pressure (nearly 60 mm Hg) as compared with other capillaries.
Glomerulus is surrounded by a membranous cover called Bowman’s capsule.
Each glomerulus is about 0.2 mm in diameter.
Glomerulus and Bowman’s capsule together constitute renal corpuscle.
Each renal tubule is divided into various part as they have different functions.
i- Proximal convulated tubule.
It is continuation of Bowman’s capsule.
ii- Loop of Henle. It is continuation of prox. conv. tubule.
* Loop of Henle has three parts.
a- descending limb,
b- u turn or bend in medulla and
c- ascending limb.
Ascending limb has initial thin segment followed by thick segment.
At the end of thick ascending limb, there is short segment called macula densa, which plays important role in controlling functions of nephron.
Urinary system
a) Anatomy and physiology of urinary system
b) Formation of urine
c) Renin Angiotensin system – Juxtaglomerular apparatus - acid base Balance
d) Clearance tests and micturition
THIS PRESENTATION INCLUDES DETAILED INFORMATION ABOUT ACCESSORY ORGANS OF DIGESTIVE SYSTEM..i,e TEETH, TONGUE, SALIVARY GLANDS, PANCREAS, LIVER AND GALL BLADDER
Urinary system
a) Anatomy and physiology of urinary system
b) Formation of urine
c) Renin Angiotensin system – Juxtaglomerular apparatus - acid base Balance
d) Clearance tests and micturition
THIS PRESENTATION INCLUDES DETAILED INFORMATION ABOUT ACCESSORY ORGANS OF DIGESTIVE SYSTEM..i,e TEETH, TONGUE, SALIVARY GLANDS, PANCREAS, LIVER AND GALL BLADDER
The presentation explains in detail the excretion process in humans, it contains all the processes occurring inside human kidney. It also gives an insight about different types of excretory waste secreted by animals in general. In all, it is a physiological summary of human kidney and excretion
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
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Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
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Urinary System
1.
2. KIDNEYS The kidney two in number reddish-brown bean-shaped organs Lie against the posterior abdominal wall at the level of T12 to L3 The R kidney is lower than the left because of the space occupied by the __ It weighs about 160 g The lateral surface is convex and the medial surface is concave, a slit called____ that receive renal nerves, blood vessels, lymphatics and ureter
3. Each kidney is about 12 cm long, 5 cm wide and about 2.5 cm thick. The left is somewhat longer, though narrower than the right . Superior to each kidneys are glands called adrenal gland The kidney adrenal gland, ureter and urinar bladder are located retroperitoneal .weight of the kidney. * adult male ranges from 4.5 – 6 ounces * adult female ranges from 4 – 5.5 ounces
4. The kidneys are protected by 3 layers of C.T. 1. Fibrous renal fascia- deep to the parietal peritoneum which binds the kidney to associated organs to abdominal wall 2. Adipose capsule- a layer of fats that cushions and hold it in place 3.Renal capsule- a fibrous sac that anchored at the hilum and encloses the rest of the kidney, it protects the kidney from infection and trauma
7. FUNCTIONS 1. They filter blood plasma, separates waste from useful chemicals and eliminates the waste by returning the rest to the bloodstream 2. They regulate blood volume and regulate osmolarity the body fluid 3. They secretes the enzyme renin which activates hormonal mechanism That control B/P and electrolyte balance
8. 4. They secrete hormone erythropoietin, which controls the RBC count and the O2 capacity of the blood 5. They detoxify free radicals of and drugs with the use peroxisomes
9.
10.
11.
12. Two (2) types of nephrons. There are two types of nephrons in the kidney, about 80% are cortical nephrons, and about 20% are juxtamedullary nephrons . 1. Cortical Nephrons 2. Juxtamedullary Nephrons
13.
14.
15.
16.
17. .in the cortex. Afferent arterioles carry blood to a glomerulus Efferent arterioles carries blood away from a glomerulus
18.
19.
20.
21. Collecting tubule- the dct several nephrons drain into straigth tubule, which passes down into the medulla. Near the papilla several collecting ducts merge to form a large PAPILLARY DUCTS.
22. URINE FORMATION Urine is composed of water, certain electrolytes, and various waste products that are filtered out of the blood system. A major part of this "cleaning" of the blood takes place in the kidneys and, in particular, in the nephrons, where the blood is filtered to produce the urine. Urination is the primary method for excreting toxins, chemicals and drugs from the body .
29. URETERS A tube that carries urine down from the kidney to the bladder. Each ureter is a muscular tube that extends from the kidney to the posterior surface of the bladder.
30. Each ureters are small tube about 25 cm long that carries urine from the renal pelvis to the urinary bladder. Smooth muscular tissue in the walls of the ureters peristaltically force the urine downward small amounts of urine are emptied into the urinary bladder from the ureters about every 10 to 15 seconds.
31.
32. (3) The inner layer, or mucous coat - is transitional epithelium that is continuous with the linings of the renal tubules and the urinary bladder.
33. LOCATION Male: the ureter enters the pelvis by crossing the bifurcation of the common iliac artery in front of the sacroiliac joint. Each ureter then runs down the lateral wall of the pelvis in front of the internal iliac artery to the region of the ischial spine and turns forward to enter the lateral angle of the bladder.
34. Female: the ureter crosses over the pelvic inlet in front of the bifurcation of the common iliac artery. It runs downward and backward in front of the internal iliac artery and behind the ovary until it reaches the region of the ischial spine. It then turns forward and medially beneath the base of the broad ligament, where it is crossed by the uterine artery. The ureter then runs forward, lateral to the lateral fornix of the vagina, to enter the bladder.
35. BLOOD SUPPLY The arterial supply of the ureters varies according to the individual and also along the length of the ureters. Branches may be received from all of the following: *Renal arteries *Abdominal aorta *Common iliac arteries *Testicular/ovarian arteries *Internal iliac arteries *Vesical/uterine arteries
36. NERVE SUPPLY Renal, testicular(or ovarian), and hypogastric plexuses(in the pelvis).
37. URINARY BLADDER The urinary bladder is a hollow, distensible, muscular organ lying in the pelvic cavity. The wall of the bladder is made mostly of a type of smooth muscle called detrusor muscle which has several layers running in different directions. The bladder is enveloped in loose connective tissue called the vesical fascia.
38.
39.
40. LOCATION It is located retroperitoneally in the pelvis just posterior to the pubic symphysis. It is held in place by ligaments attached to pelvic bones.
41. FUNCTION It stores urine as temporarily reservoir for urine It is the organ that collects urine excreted by kidneys prior to disposal by urination. Urine enters the bladder via the ureters and emits via the urethra.
42.
43.
44.
45. LIGAMENTS The bladder is connected to the pelvic wall by the fascia endopelvina * Pubovesicales – muscle fibers that strengthens the front of fascial attachment. * Rectovesicales – wherein other muscular fibers constitute and run from the fundus of the bladder to the sides of the rectum, in the sacrogenital folds. * Middle umbilical ligament - formed when the vertex of the bladder is joined to the umbilicus by the remains of the urachus. Broad at its attachment to the bladder but narrowing as it ascends.
46.
47. BLOOD SUPPLY Arterial supply comes mostly from branches of the internal iliac arteries. Female: anteriosuperior parts - superior vesical arteries, posterioinferior parts - vaginal Arteries Male: anteriosuperior parts – superior vesical arteries, posterioinferior parts - inferior vesical arteries
48. Venous drainage is via venous plexuses. These drain via veins that correspond to the arteries into the internal iliac veins. Female: vesical venous plexus Male: vesical venous plexus, prostatic venous plexus
49. NERVE SUPPLY The nerves supplying the bladder form the vesical nervous plexus and are both parasympathetic and sympathetic.
50.
51. URETHRA Muscular tube that drains urine from the bladder and conveys it out of the body. Its wall is lined with mucous membranes and contains a relatively thick layer of smooth muscle tissue. It also contains numerous mucous glands called urethral glands , that secrete mucus into the urethral canal.
52.
53. FUNCTION * urinary canal and a passageway of cells and secretions from various reproductive organs Or it also affords an exit for the seminal products * secretion of prostatic and bulbo-urethral glands
54. THREE PORTIONS (1) PROSTATIC PORTION The widest and most dilatable part of the canal and it’s about 3 cm. long
55. LOCATION Runs almost vertically through the prostate from its base to its apex, lying nearer its anterior than its posterior surface; the form of the canal is spindle-shaped, being wider in the middle than at either extremity, and narrowest below, where it joins the membranous portion.
56. FUNCTION When distended, it may serve to prevent the passage of the semen backward into the bladder.
57.
58. LOCATION Extend between the apex of the prostate and the bulb of the corpus spongiosum. It runs downwards and forwards through the urogenital diaphragm. A small portion is passing through the external urethral sphincter.
59.
60. FEMALE URETHRA - is a narrow membranous canal, about 4 cm. long in length - it is placed behind the symphysis pubis, imbedded in the anterior wall of the vagina. Ends at the external orifice of urethra, which is the point at which the urine leaves the body. This is located between the clitoris and the vaginal opening
62. BLOOD SUPPLY The female urethra receives branches from the: *internal pudendal arteries *vaginal arteries
63. The male urethra receives branches from the: *internal pudendal arteries *arteries supplying the prostate. Veins accompany the arteries and have similar names.
64. NERVE SUPPLY The urethra receives innervation from the pudendal nerve (S2,S3,S4). Afferents from the urethra travel in the pelvic splanchnic nerves.