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International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 07 Issue: 03 | Mar 2020 www.irjet.net p-ISSN: 2395-0072
© 2020, IRJET | Impact Factor value: 7.34 | ISO 9001:2008 Certified Journal | Page 4272
Lung Cancer Detection using GLCM and Convolutional Neural Network
Suresh Babu.P1, Jennifer.J2, Hesima.C3 , Preethi.S4
[1]Assistant Professor-III, Department of Information Technology, Velammal College of Engineering and
Technology, Madurai, Tamil Nadu, India.
[2][3][4]Department of Information Technology, Velammal College of Engineering and Technology, Madurai,
Tamil Nadu, India
---------------------------------------------------------------------***----------------------------------------------------------------------
Abstract - Cancer is one of the deadliest diseases leading to
innumerable deaths worldwide. According to WHO (World
Health Organization) lung cancer contributes about 14 per
cent among all the cancers. Therefore, early detection and
treatment is very much required. ComputedTomography(CT)
scan can provide valuable information in the diagnosisoflung
diseases. The main objective of this work is to classify the
tumors found in lung as malignant or benign by means of
Convolutional Neural Network(CNN). The accuracy obtained
by means of CNN is 96%, which is more efficient when
compared to accuracy obtained by the traditional neural
network systems.
KeyWords-ComputedTomography(CT),GrayLevel
Co-occurence Matrix(GLCM), Convolution Neural
Network (CNN).
1. INTRODUCTION
Cancer is the most prevalent terminal disease globally,
accounting for an estimated 9.6 million deaths in 2018. Of
many types of cancers, lung cancer is one of the frequently
occurring diseases that causes death andisidentifiedin both
genders over an estimated death of 1.76 million in 2018.
Although surgery,radiationtherapy,andchemotherapyhave
been used in the treatment of lung cancer, the five year
survival rate for all stages combined is only 14%. This has
not changed in the past three decades [1]. It is difficult to
detect because it arises and shows symptoms in final stage.
However, mortality rate and probability can be reduced by
early detection and treatment of the disease. Best imaging
technique CT imaging are reliable for lung cancer diagnosis
because it can disclose every suspected and unsuspected
lung cancer modules.
The proposed methodology has five phases for the
classification of lung cancer. In phase one, the required data
is collected from the database
https://www.kaggle.com/datasets. In phase two removal of
noise is done by using the Median filter. In phase three, the
taken input images are segmented using K Meansclustering.
After segmentation, in phase four, features are
extracted using GLCM (Gray Level Co-occurrence Matrix).
These extracted features are used in phase five for
classification purpose which is carried by CNN
(Convolutional Neural Network)
2. METHODOLGY
To improve the detection of lung cancer in the CT images
there are four main steps involved. At each step, various
techniques are appliedwhich resultedindifferentaccuracies
in detecting the lung cancer. Firstly, thelungCTimageis pre-
processed to remove any noises that exists in the image.
Secondly, the image is segmented to get Region of Interest
(ROI). Thirdly, feature extraction is applied to extract
features like energy, entropy, variance. Finally, different
classification algorithm is applied on the extracted features
of the lung CT image.
Fig 1: Steps involved to detect Lung Cancer
International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 07 Issue: 03 | Mar 2020 www.irjet.net p-ISSN: 2395-0072
© 2020, IRJET | Impact Factor value: 7.34 | ISO 9001:2008 Certified Journal | Page 4273
2.1. Input CT lung Images
The lung CT images having low noise when compared to
scan image and MRI image. So we can take the CT images for
detecting the lungs. The main advantage of the computer
tomography image having better clarity, low noise and
distortion. The mean and Variance can be easily calculated.
The calculated value is very closer to the original value.
Fig.2 The Lung CT Image
2.2. Preprocessing
Image pre-processing is the first and important technique
involved in lung cancer detection. Pre-processing technique
is needed to improve the detectionaccuracyandtoeliminate
some regions of CT Image such as background and
surrounding tissues or vessels. In preprocessing stage, the
median filter is used to restore the image under test by
minimizing the effects of the degradations during
acquisition..The median filter simply replaces each pixel
value with the median value of its neighbors including itself.
Hence, the pixel values which are very different from their
neighbors will be eliminated[2].
2.3. Segmentation
The goal of segmentation is to simplify and/or change the
representation of an image into something that is more
meaningful and easier to analyze. Image Segmentation is
typically used to locate objectsandboundaries(lines,curves,
etc.) in images. More precisely, image segmentation is the
process of assigning a label to every pixel in an image such
that pixels with the same label share certain visual
characteristics [3]. The result of image segmentation is a set
of segments that collectively cover the entire image, or a set
of contours extracted from the image (edge detection). Each
of the pixels in a region is similar with respect to some
characteristic or computed property,suchascolor,intensity,
or texture. Adjacent regions are significantly different with
respect to the same characteristic(s).
2.4. Feature Extraction
The Image features Extraction stage is very importantinour
working in image processing techniques which using
algorithms and techniques to detect and isolate various
desired portions or shapes (features) of an image. After the
segmentation is performed on lung region, the features can
be obtained from it and the diagnosis rule canbedesigned to
exactly detect the cancer nodules in thelungs.Thisdiagnosis
rules can eliminate the false detection of cancer nodules
resulted in segmentation and provides better diagnosis. In
the literature we found among the features used in the
diagnostic indicators:
• Area of the interest
• Calcification
• Shape and Size of nodule
• Contrast Enhancement
2.5. Classification
Feature extraction techniques in image processing are used
for extracting desired features from image like portions,
shapes of an image. Normality and abnormality of an image
can be determined in this stage. The detected features
provide a basis for process of classification. Variousfeatures
of an image can be area, perimeter, eccentricity, intensity,
etc. Various feature extraction techniques whichcanbeused
are histogram of oriented gradients, local binary patterns,
Gray-Level Co-Occurrence Matrix. The lung cancer can be
detected in the classification stage by applying back-
propagation, and in the pre-processing stage
3. RELATED WORKS
In this paper [4], input color images were first converted
into grey scale images as processing of grey scale image is
easier than that of the color images. histogram equalization
was then applied to the images for obtaining the sharp
borders which can help in furtheranalysisasithighlights the
borders thereby increasing the contrast of the images.
thresholding was applied and features wereextractedbased
on the pixel value. By applying Baack Propagation Network,
an overall efficiency of 78 percent was achieved.
In this paper [5], detection of cancerwascarriedoutwiththe
help of ANN (Artificial Neural Network back- propagation).
From the lung cancer database, a total of 50 images were
considered and these images were divided into two groups-
cancer and non-cancer images. The features were extracted
International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 07 Issue: 03 | Mar 2020 www.irjet.net p-ISSN: 2395-0072
© 2020, IRJET | Impact Factor value: 7.34 | ISO 9001:2008 Certified Journal | Page 4274
with the help of GLCM (Gray Level Co-occurrence Matrix)
and these were given to ANN. The cancer was detected and
80% of accuracy was obtained.
In this paper [6], proposed methodology used CT
(Computerized Tomography) scanimages.Themethodology
has several steps such as pre-processing where the noise of
the images is removed. The second step is image
segmentation where over segmentation is removed using
Marker Controlled WatershedSegmentation.Thesegmented
image was then applied to Binarization and masking
technique. Watershed achieved more accuracy when
compared with Threshold which is 85.27 percent.
In this paper [7], two segmentation methods were used for
early detection of lung cancer.Thefirstmethod wasHopfield
Neural Network (HNN) and the second methodwasFuzzyC-
Mean (FCM) algorithm. With the help of HNN, nuclei and
cytoplasm regions were extracted successfully. HNN was
preferred as FCM failed in extracting these features with
accuracy.
This paper [8], proposed an automatic detection of lung
cancer by suing CT scan images. While diagnosing lung
cancer, lung nodule detection plays an important role.
Therefore, FCN (Fully Convolutional Network) was selected
for gaining more accuracy. First, FCN was used for
segmentation and then lung nodules were detected. The
proposed method was able to detect the lung nodules with
100 percent accuracy.
4. RESULT AND DISCUSSION
Phase 1: Here figure 3a and 3b represents the normal and
abnormal images taken from the dataset for classification
purpose. All the collected cancerous and non-cancerous
images are CT Scan images.
Figure 3a: Normal Lung image
Figure 3b: Abnormal Lung image
Phase 2: Noise is removed successfully with the help of
median filter while preserving all the edges carefully for
classification purpose.
Phase 3: After filtering of image, segmentation of the image
was done using K Means clustering. It was successfully
applied and better results were shown.
Phase 4: The features of the input image are extracted by
using GLCM. These are given to the classifier for the further
classification.
The above image (as depicted in Figure 2b) when processed,
provides the following output
Figure 4a: Processes Involved in Lung Cancer Detection
International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 07 Issue: 03 | Mar 2020 www.irjet.net p-ISSN: 2395-0072
© 2020, IRJET | Impact Factor value: 7.34 | ISO 9001:2008 Certified Journal | Page 4275
Figure 4b: Extracted Regions
Figure 4c: Accuracy of the Abnormal Lung Image
5. CONCLUSION AND FUTURE WORK
A convolutional neural network based system was
implemented to detect the malignancy tissues presentinthe
input lung CT image. Lung image with differentshape,size of
the cancerous tissues has been fed at the input for training
the system. The proposed system is able to detect the
presence and absence of cancerous cells with accuracy of
about 96%.
In addition to deep convolutional network, the same dataset
was classified by multilayer perceptron network Back
propagation algorithmwith usingGLCM features.The results
show only 93% accuracy [9].
In this proposed work, the specificity obtained is 100%
which shows that that there is no false positive detection.
Also, the accuracy, sensitivity and specificityoftheproposed
system is high when compared to previously available
conventional neural network based systems.
In the near future, the system will be trained with large
datasets to diagnose the type of cancer with its size and
shape. The overall accuracy of the system can be improved
using 3D Convolutional Neural Network and also by
improving the hidden neurons with deep network.
REFERENCES
[1] Disha Sharma, Gagandeep Jindal, "Identifying Lung
Cancer Using Image Processing Techniques", International
Conference on Computational Techniques and Artificial
Intelligence (ICCTAI'2011)
[2] M.S. Al-Tarawneh, “Lung cancer detection using image
processing techniques,” Leonardo Electronic Journal of
Practices and Technologies, vol. 20, pp. 147– 58, May 2012
[3] Linda G. Shapiro and G.C. Stockman., Computer Vision:
Theory and Applications. 2001: Prentice Hall.
[4] Kalaivani, S., Chatterjee, P., Juyal, S., & Gupta, R. (2017,
April). Lung cancer detection using digital image processing
and artificial neural networks. In 2017 International
conference of Electronics, Communication and Aerospace
Technology (ICECA) (Vol. 2, pp. 100-103). IEEE. 9
[5] Anifah, L..., Haryanto, Harimurti, R.P., Permatasari, Z.,
Rusimamto, P.W., & Muhamad, A.R. (2017). Cancer lungs
detection on CT scan image using artificial neural network
backpropagation based gray level coocurrence matrices
feature. 2017 International Conference on Advanced
Computer Science and Information Systems (ICACSIS).
[6] Patil, B. G., & Jain, S. N. (2014). Cancer cells detection
using digital image processing methods. International
Journal of Latest Trends in Engineering and Technology,
3(4), 45-49.
[7] Taher, F., & Sammouda, R. (2011, February). Lungcancer
detection by using artificial neural network and fuzzy
clustering methods. In 2011 IEEE GCC Conference and
Exhibition (GCC) (pp. 295-298). IEEE.
[8] Chunran, Y., Yuanvuan, W., & Yi, G.X. (2018). Automatic
Detection and Segmentation of Lung Nodule on
CT Images. 2018 11th International Congress on Image and
Signal Processing, BioMedical Engineering and Informatics
(CISP-BMEI), 1-6.
[9] A.Kavitha and P.Senthil,” Design Model of Retiming
Multiplier For FIR Filter &its Verification”, International
Journal of Pure and Applied Mathematics, Vol116 No12,
2017, pp. 239-247

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IRJET - Lung Cancer Detection using GLCM and Convolutional Neural Network

  • 1. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 07 Issue: 03 | Mar 2020 www.irjet.net p-ISSN: 2395-0072 © 2020, IRJET | Impact Factor value: 7.34 | ISO 9001:2008 Certified Journal | Page 4272 Lung Cancer Detection using GLCM and Convolutional Neural Network Suresh Babu.P1, Jennifer.J2, Hesima.C3 , Preethi.S4 [1]Assistant Professor-III, Department of Information Technology, Velammal College of Engineering and Technology, Madurai, Tamil Nadu, India. [2][3][4]Department of Information Technology, Velammal College of Engineering and Technology, Madurai, Tamil Nadu, India ---------------------------------------------------------------------***---------------------------------------------------------------------- Abstract - Cancer is one of the deadliest diseases leading to innumerable deaths worldwide. According to WHO (World Health Organization) lung cancer contributes about 14 per cent among all the cancers. Therefore, early detection and treatment is very much required. ComputedTomography(CT) scan can provide valuable information in the diagnosisoflung diseases. The main objective of this work is to classify the tumors found in lung as malignant or benign by means of Convolutional Neural Network(CNN). The accuracy obtained by means of CNN is 96%, which is more efficient when compared to accuracy obtained by the traditional neural network systems. KeyWords-ComputedTomography(CT),GrayLevel Co-occurence Matrix(GLCM), Convolution Neural Network (CNN). 1. INTRODUCTION Cancer is the most prevalent terminal disease globally, accounting for an estimated 9.6 million deaths in 2018. Of many types of cancers, lung cancer is one of the frequently occurring diseases that causes death andisidentifiedin both genders over an estimated death of 1.76 million in 2018. Although surgery,radiationtherapy,andchemotherapyhave been used in the treatment of lung cancer, the five year survival rate for all stages combined is only 14%. This has not changed in the past three decades [1]. It is difficult to detect because it arises and shows symptoms in final stage. However, mortality rate and probability can be reduced by early detection and treatment of the disease. Best imaging technique CT imaging are reliable for lung cancer diagnosis because it can disclose every suspected and unsuspected lung cancer modules. The proposed methodology has five phases for the classification of lung cancer. In phase one, the required data is collected from the database https://www.kaggle.com/datasets. In phase two removal of noise is done by using the Median filter. In phase three, the taken input images are segmented using K Meansclustering. After segmentation, in phase four, features are extracted using GLCM (Gray Level Co-occurrence Matrix). These extracted features are used in phase five for classification purpose which is carried by CNN (Convolutional Neural Network) 2. METHODOLGY To improve the detection of lung cancer in the CT images there are four main steps involved. At each step, various techniques are appliedwhich resultedindifferentaccuracies in detecting the lung cancer. Firstly, thelungCTimageis pre- processed to remove any noises that exists in the image. Secondly, the image is segmented to get Region of Interest (ROI). Thirdly, feature extraction is applied to extract features like energy, entropy, variance. Finally, different classification algorithm is applied on the extracted features of the lung CT image. Fig 1: Steps involved to detect Lung Cancer
  • 2. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 07 Issue: 03 | Mar 2020 www.irjet.net p-ISSN: 2395-0072 © 2020, IRJET | Impact Factor value: 7.34 | ISO 9001:2008 Certified Journal | Page 4273 2.1. Input CT lung Images The lung CT images having low noise when compared to scan image and MRI image. So we can take the CT images for detecting the lungs. The main advantage of the computer tomography image having better clarity, low noise and distortion. The mean and Variance can be easily calculated. The calculated value is very closer to the original value. Fig.2 The Lung CT Image 2.2. Preprocessing Image pre-processing is the first and important technique involved in lung cancer detection. Pre-processing technique is needed to improve the detectionaccuracyandtoeliminate some regions of CT Image such as background and surrounding tissues or vessels. In preprocessing stage, the median filter is used to restore the image under test by minimizing the effects of the degradations during acquisition..The median filter simply replaces each pixel value with the median value of its neighbors including itself. Hence, the pixel values which are very different from their neighbors will be eliminated[2]. 2.3. Segmentation The goal of segmentation is to simplify and/or change the representation of an image into something that is more meaningful and easier to analyze. Image Segmentation is typically used to locate objectsandboundaries(lines,curves, etc.) in images. More precisely, image segmentation is the process of assigning a label to every pixel in an image such that pixels with the same label share certain visual characteristics [3]. The result of image segmentation is a set of segments that collectively cover the entire image, or a set of contours extracted from the image (edge detection). Each of the pixels in a region is similar with respect to some characteristic or computed property,suchascolor,intensity, or texture. Adjacent regions are significantly different with respect to the same characteristic(s). 2.4. Feature Extraction The Image features Extraction stage is very importantinour working in image processing techniques which using algorithms and techniques to detect and isolate various desired portions or shapes (features) of an image. After the segmentation is performed on lung region, the features can be obtained from it and the diagnosis rule canbedesigned to exactly detect the cancer nodules in thelungs.Thisdiagnosis rules can eliminate the false detection of cancer nodules resulted in segmentation and provides better diagnosis. In the literature we found among the features used in the diagnostic indicators: • Area of the interest • Calcification • Shape and Size of nodule • Contrast Enhancement 2.5. Classification Feature extraction techniques in image processing are used for extracting desired features from image like portions, shapes of an image. Normality and abnormality of an image can be determined in this stage. The detected features provide a basis for process of classification. Variousfeatures of an image can be area, perimeter, eccentricity, intensity, etc. Various feature extraction techniques whichcanbeused are histogram of oriented gradients, local binary patterns, Gray-Level Co-Occurrence Matrix. The lung cancer can be detected in the classification stage by applying back- propagation, and in the pre-processing stage 3. RELATED WORKS In this paper [4], input color images were first converted into grey scale images as processing of grey scale image is easier than that of the color images. histogram equalization was then applied to the images for obtaining the sharp borders which can help in furtheranalysisasithighlights the borders thereby increasing the contrast of the images. thresholding was applied and features wereextractedbased on the pixel value. By applying Baack Propagation Network, an overall efficiency of 78 percent was achieved. In this paper [5], detection of cancerwascarriedoutwiththe help of ANN (Artificial Neural Network back- propagation). From the lung cancer database, a total of 50 images were considered and these images were divided into two groups- cancer and non-cancer images. The features were extracted
  • 3. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 07 Issue: 03 | Mar 2020 www.irjet.net p-ISSN: 2395-0072 © 2020, IRJET | Impact Factor value: 7.34 | ISO 9001:2008 Certified Journal | Page 4274 with the help of GLCM (Gray Level Co-occurrence Matrix) and these were given to ANN. The cancer was detected and 80% of accuracy was obtained. In this paper [6], proposed methodology used CT (Computerized Tomography) scanimages.Themethodology has several steps such as pre-processing where the noise of the images is removed. The second step is image segmentation where over segmentation is removed using Marker Controlled WatershedSegmentation.Thesegmented image was then applied to Binarization and masking technique. Watershed achieved more accuracy when compared with Threshold which is 85.27 percent. In this paper [7], two segmentation methods were used for early detection of lung cancer.Thefirstmethod wasHopfield Neural Network (HNN) and the second methodwasFuzzyC- Mean (FCM) algorithm. With the help of HNN, nuclei and cytoplasm regions were extracted successfully. HNN was preferred as FCM failed in extracting these features with accuracy. This paper [8], proposed an automatic detection of lung cancer by suing CT scan images. While diagnosing lung cancer, lung nodule detection plays an important role. Therefore, FCN (Fully Convolutional Network) was selected for gaining more accuracy. First, FCN was used for segmentation and then lung nodules were detected. The proposed method was able to detect the lung nodules with 100 percent accuracy. 4. RESULT AND DISCUSSION Phase 1: Here figure 3a and 3b represents the normal and abnormal images taken from the dataset for classification purpose. All the collected cancerous and non-cancerous images are CT Scan images. Figure 3a: Normal Lung image Figure 3b: Abnormal Lung image Phase 2: Noise is removed successfully with the help of median filter while preserving all the edges carefully for classification purpose. Phase 3: After filtering of image, segmentation of the image was done using K Means clustering. It was successfully applied and better results were shown. Phase 4: The features of the input image are extracted by using GLCM. These are given to the classifier for the further classification. The above image (as depicted in Figure 2b) when processed, provides the following output Figure 4a: Processes Involved in Lung Cancer Detection
  • 4. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 07 Issue: 03 | Mar 2020 www.irjet.net p-ISSN: 2395-0072 © 2020, IRJET | Impact Factor value: 7.34 | ISO 9001:2008 Certified Journal | Page 4275 Figure 4b: Extracted Regions Figure 4c: Accuracy of the Abnormal Lung Image 5. CONCLUSION AND FUTURE WORK A convolutional neural network based system was implemented to detect the malignancy tissues presentinthe input lung CT image. Lung image with differentshape,size of the cancerous tissues has been fed at the input for training the system. The proposed system is able to detect the presence and absence of cancerous cells with accuracy of about 96%. In addition to deep convolutional network, the same dataset was classified by multilayer perceptron network Back propagation algorithmwith usingGLCM features.The results show only 93% accuracy [9]. In this proposed work, the specificity obtained is 100% which shows that that there is no false positive detection. Also, the accuracy, sensitivity and specificityoftheproposed system is high when compared to previously available conventional neural network based systems. In the near future, the system will be trained with large datasets to diagnose the type of cancer with its size and shape. The overall accuracy of the system can be improved using 3D Convolutional Neural Network and also by improving the hidden neurons with deep network. REFERENCES [1] Disha Sharma, Gagandeep Jindal, "Identifying Lung Cancer Using Image Processing Techniques", International Conference on Computational Techniques and Artificial Intelligence (ICCTAI'2011) [2] M.S. Al-Tarawneh, “Lung cancer detection using image processing techniques,” Leonardo Electronic Journal of Practices and Technologies, vol. 20, pp. 147– 58, May 2012 [3] Linda G. Shapiro and G.C. Stockman., Computer Vision: Theory and Applications. 2001: Prentice Hall. [4] Kalaivani, S., Chatterjee, P., Juyal, S., & Gupta, R. (2017, April). Lung cancer detection using digital image processing and artificial neural networks. In 2017 International conference of Electronics, Communication and Aerospace Technology (ICECA) (Vol. 2, pp. 100-103). IEEE. 9 [5] Anifah, L..., Haryanto, Harimurti, R.P., Permatasari, Z., Rusimamto, P.W., & Muhamad, A.R. (2017). Cancer lungs detection on CT scan image using artificial neural network backpropagation based gray level coocurrence matrices feature. 2017 International Conference on Advanced Computer Science and Information Systems (ICACSIS). [6] Patil, B. G., & Jain, S. N. (2014). Cancer cells detection using digital image processing methods. International Journal of Latest Trends in Engineering and Technology, 3(4), 45-49. [7] Taher, F., & Sammouda, R. (2011, February). Lungcancer detection by using artificial neural network and fuzzy clustering methods. In 2011 IEEE GCC Conference and Exhibition (GCC) (pp. 295-298). IEEE. [8] Chunran, Y., Yuanvuan, W., & Yi, G.X. (2018). Automatic Detection and Segmentation of Lung Nodule on CT Images. 2018 11th International Congress on Image and Signal Processing, BioMedical Engineering and Informatics (CISP-BMEI), 1-6. [9] A.Kavitha and P.Senthil,” Design Model of Retiming Multiplier For FIR Filter &its Verification”, International Journal of Pure and Applied Mathematics, Vol116 No12, 2017, pp. 239-247