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International Journal on Recent and Innovation Trends in Computing and Communication ISSN: 2321-8169
Volume: 5 Issue: 11 184 – 187
_______________________________________________________________________________________________
184
IJRITCC | November 2017, Available @ http://www.ijritcc.org
_______________________________________________________________________________________
Mass Segmentation Techniques
For Lung Cancer CT Images
Rakesh Kumar Khare
Associate Professor (CSE)
SSITM
Bhilai, India
rakesh_khare2001@yahoo.com
G. R. Sinha
Professor (ECE) and Dean (IQAC)
CMR Technical campus
Hyderabad, India
ganeshsinha2003@gmail.com
Sushil Kumar
Professor and Principal
SRSIT
Raipur, India
sk1_bit@rediffmail.com
Abstract— Mass segmentation methods are commonly used nowadays in modern diagnostic centers and research centers working in the field of
lung cancer detection and diagnosis. We have implemented k-means and fuzzy cluster means (FCM) techniques for mass segmentation of lung
CT images. The methods were compared in terms of area, perimeter and diameter. FCM outperforms K-means in terms of better detection of
lung cancer area and effective values of dimensional features of lung cancer as compared to K-means method.
Keywords- Computed tomography (CT), Fuzzy c-means (FCM), K-means.
__________________________________________________*****_________________________________________________
I. INTRODUCTION
Presently low dose CT is the core interest area for detection of
lung cancer. Mass region detection is a rising research work
field that has received continuous focus in the research group
over the past decades. Image segmentation is a process to
partitioned digital image into several regions [1-9]. Each of the
pixels in the region has same characteristics like color,
intensity, texture etc. For early diagnosis of lung abnormalities
CT images are widely used by radiologist to detect cancer
nodule with some feature such as area, diameter and size
[13].The efficient segmentation algorithm provides good
accuracy and higher decision confidence value to the
radiologist to make better remark. There are several issues
related to image segmentation that required detailed review of
literature. The most important part of image segmentation is to
detect the proper area of mass by selecting suitable method for
isolating different object from the background. The two
existing clustering techniques have been used for segmentation
purpose but for actual segmentation some morphological
operation has been used over clusters. The performance of
these two techniques is also evaluated and results are screened.
Judice et al. (2013) presented an automated computer added
diagnosis (CAD) system in which wiener filter is used to
remove noise. Hidden Markov Model algorithm was proposed
which increase the confidence level of diagnosis and taken less
time also[5].
Maivizhi et al. (2013) used K-means and Fuzzy c-means
algorithm to find out cancer affected gene and proposed
modified fuzzy c-means algorithm to grasp cancerous nodule.
An experimental system has been implemented and tested to
demonstrate the effectiveness of proposed method on the basis
of parameter such as no of cluster, time, space and
performance calculation and cluster evolution [9]. Niranjana et
al. (2014) worked on Neural fuzzy Network (NFN) and a
Fuzzy c-mean (FCM) clustering algorithm for segmenting the
early stage of lung cancer. A thresholding technique as a pre-
processing step in all images to extract the nuclei regions was
applied, because most of the quantitative procedures are based
on its nuclei feature. This thresholding algorithm had
succeeded in extracting the nuclei regions. Moreover, it
succeeded in determining the best range of thresholding
values. The NFN and FCM methods are designed to classify
the image of N pixels among M classes and tested over many
color images, and NFN has shown a better classification result
than FCM [11]. Kumar et al. (2013) compared Artificial
Neural Network (ANN), Fuzzy C-Mean (FCM) and Fuzzy
Min-Max Neural network (FMNN) which is very effective and
helpful in cancer diagnosis for its several advantages. The
motive behind that the fault tolerance, flexibility, non linearity
are the factors of artificial neural network. FCM provides
finest findings for overlapped data set; data point may be
connected with more than one cluster centre. Non-linear
separability, soft and hard decision, less training time, online
adaptation is the advantages of FMNN. The classification
methods are applied to both FMN and FCM on the X-ray 130
cancerous and noncancerous datasets available. Hence using
FCM and FMNN to diagnose lung cancer is good[12].
Jaffer et al. (2009) proposed a method by using Fuzzy c-mean
(FCM) and morphological techniques for detection of tumor
from lung computed tomography (CT) images. Initially, the
automated segmentation of lungs has been done using fuzzy.
Region of interests (ROIs) have been extracted by using 8
directional searches slice by slice and then 3D ROI image
have been constructed. A 3D template has been constructed
and convolves with the 3D ROI image. Finally FCM have
been used to extract ROI that contain nodule. The technique
was tested against the 50 datasets of different patients received
from Aga Khan Medical University, Pakistan and Lung Image
Database Consortium (LIDC) dataset [22]. Patel et al. (2010)
developed an adaptive k means clustering algorithm for
mammographic images segmentation for detection of breast
cancer at early stage. The feature extraction is performed with
the data base of 150 breast cancer images taken from BSR
International Journal on Recent and Innovation Trends in Computing and Communication ISSN: 2321-8169
Volume: 5 Issue: 11 184 – 187
_______________________________________________________________________________________________
185
IJRITCC | November 2017, Available @ http://www.ijritcc.org
_______________________________________________________________________________________
APPOL with the parameter such as number, color and shape of
object[23].
Fatma et al. (2011) presented Hopfield Neural Network (HNN)
and a Fuzzy c-mean (FCM) clustering algorithm, for
segmenting sputum color images for detection of lung cancer in
early stages. The above methods are designed to classify the
image of N pixels among M classes. They used 1000 sputum
color images to test both methods, and HNN has shown a better
classification result than FCM, the HNN succeeded in
extracting the nuclei and cytoplasm regions [33]. Kaur et al.
(2015) reviewed two methods i.e. Neural Network (NN) and
Fuzzy c-mean Clustering Algorithm for sputum color images
for early diagnose of lung cancer. They compared these two
methods with their advantage and disadvantage and conclude
that Fuzzy c-mean (FCM) clustering algorithm is not good at
low intensity variations [35].
II. PROPOSED METHODOLOGY
The proposed method follows several steps which include
taking input image for pre processing for removal of noise and
enhance the contrast of input image for better segmentation
Fig. 1: Flow diagram of proposed system
using various clustering techniques such as K-means and
Fuzzy c-means. To find out accurate mass region process such
as binary, dilation, erosion, opening and closing are performed
step by step on each image. Finally, evaluate parameter like
area, diameter and perimeter for comparison of better method.
The flow diagram of proposed system has shown in Fig. 1.
III. RESULTS AND DISCUSSION
In this work we have compared two clustering techniques K-
means and FCM for better lung mass segmentation in CT
images that are used in CAD system. Both the methods are
compared with several morphological operation and from the
Fig. 2 it has been notice that the K-means techniques gives
little bit smooth rounding edges for suspected nodule whereas
FCM bordered more accurately because cancer nodule has not
any specific size and somehow in zigzag pattern. The
parameter such as area, perimeter and diameter calculated by
FCM are more accurate as compare to K-means for each
nodule. These parameters calculating by K-means is lesser due
to smooth surfacing in nodule but FCM calculate these
parameter values for each nodule efficiently which helps to
further classify the nodule for T staging. Both the techniques
gives prominent result but FCM is better for marking proper
suspected area in case of single and multiple nodule detection
in CT image of lung The comparative study of K-means and
Fuzzy c-means algorithms in terms of several parameters such
as area, diameter and perimeter has been evaluated.
Experimental data have been consisting of more than 50
images and comparative results of 6 images are shown in
Table 1.
Table 1: Comparison of Segmentation Techniques
Image No. Parameter
K-means
(pixel)
FCM
(pixel)
cp1
Area 1839 1891
Perimeter 162.8 182.5
Diameter 48.4 49.1
cp2
Area 919 938
Perimeter 114.3 116.1
Diameter 34.4 34.6
cp3
Area 507 513
Perimeter 91.3 89.6
Diameter 25.4 25.6
cp4
Area 245 277
Perimeter 55.7 59.7
Diameter 17.7 18.8
cp5
Area 521 532
Perimeter 90.1 94.3
Diameter 25.8 26
cp6
Area 914 918
Perimeter 190.5 189.3
Diameter 34.1 34.2
Read the CT Image of Lung to be
Segmented and Classified
Start
Apply Pre Processing: i) Noise
Removal ii) Contrast Enhancement
Apply Image Clustering Techniques
( k-means and Fuzzy c- means)
Apply Morphological Processing
i) Dilation and Erosion
ii) Opening and Closing
Calculate Various Suspected Region
with Parameter: i) Area ii) Perimeter
iii) Diameter
Stop
International Journal on Recent and Innovation Trends in Computing and Communication ISSN: 2321-8169
Volume: 5 Issue: 11 184 – 187
_______________________________________________________________________________________________
186
IJRITCC | November 2017, Available @ http://www.ijritcc.org
_______________________________________________________________________________________
(a) (e)
(b) (f)
(c) (g)
(d) (h)
Fig. 2 Result of K-means (a) Original image (b) Region
of Interest (c) Binary image (d) Segmented Image
Result of FCM (e) Original image (f)Region of
Interest (g) Binary image (h) Segmented Image
IV. CONCLUSION
This work presents the better CAD system for automatic
detection of lung nodule using segmentation techniques like k-
means and fuzzy c-means (FCM) and carried out with some
morphological operation for proper extraction of affected lung
area. These algorithms tested over 50 images and found FCM
is better than k-means in all respect for efficient detection of
mass region inside lung CT images.
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International Journal on Recent and Innovation Trends in Computing and Communication ISSN: 2321-8169
Volume: 5 Issue: 11 184 – 187
_______________________________________________________________________________________________
187
IJRITCC | November 2017, Available @ http://www.ijritcc.org
_______________________________________________________________________________________
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Mass Segmentation Techniques For Lung Cancer CT Images

  • 1. International Journal on Recent and Innovation Trends in Computing and Communication ISSN: 2321-8169 Volume: 5 Issue: 11 184 – 187 _______________________________________________________________________________________________ 184 IJRITCC | November 2017, Available @ http://www.ijritcc.org _______________________________________________________________________________________ Mass Segmentation Techniques For Lung Cancer CT Images Rakesh Kumar Khare Associate Professor (CSE) SSITM Bhilai, India rakesh_khare2001@yahoo.com G. R. Sinha Professor (ECE) and Dean (IQAC) CMR Technical campus Hyderabad, India ganeshsinha2003@gmail.com Sushil Kumar Professor and Principal SRSIT Raipur, India sk1_bit@rediffmail.com Abstract— Mass segmentation methods are commonly used nowadays in modern diagnostic centers and research centers working in the field of lung cancer detection and diagnosis. We have implemented k-means and fuzzy cluster means (FCM) techniques for mass segmentation of lung CT images. The methods were compared in terms of area, perimeter and diameter. FCM outperforms K-means in terms of better detection of lung cancer area and effective values of dimensional features of lung cancer as compared to K-means method. Keywords- Computed tomography (CT), Fuzzy c-means (FCM), K-means. __________________________________________________*****_________________________________________________ I. INTRODUCTION Presently low dose CT is the core interest area for detection of lung cancer. Mass region detection is a rising research work field that has received continuous focus in the research group over the past decades. Image segmentation is a process to partitioned digital image into several regions [1-9]. Each of the pixels in the region has same characteristics like color, intensity, texture etc. For early diagnosis of lung abnormalities CT images are widely used by radiologist to detect cancer nodule with some feature such as area, diameter and size [13].The efficient segmentation algorithm provides good accuracy and higher decision confidence value to the radiologist to make better remark. There are several issues related to image segmentation that required detailed review of literature. The most important part of image segmentation is to detect the proper area of mass by selecting suitable method for isolating different object from the background. The two existing clustering techniques have been used for segmentation purpose but for actual segmentation some morphological operation has been used over clusters. The performance of these two techniques is also evaluated and results are screened. Judice et al. (2013) presented an automated computer added diagnosis (CAD) system in which wiener filter is used to remove noise. Hidden Markov Model algorithm was proposed which increase the confidence level of diagnosis and taken less time also[5]. Maivizhi et al. (2013) used K-means and Fuzzy c-means algorithm to find out cancer affected gene and proposed modified fuzzy c-means algorithm to grasp cancerous nodule. An experimental system has been implemented and tested to demonstrate the effectiveness of proposed method on the basis of parameter such as no of cluster, time, space and performance calculation and cluster evolution [9]. Niranjana et al. (2014) worked on Neural fuzzy Network (NFN) and a Fuzzy c-mean (FCM) clustering algorithm for segmenting the early stage of lung cancer. A thresholding technique as a pre- processing step in all images to extract the nuclei regions was applied, because most of the quantitative procedures are based on its nuclei feature. This thresholding algorithm had succeeded in extracting the nuclei regions. Moreover, it succeeded in determining the best range of thresholding values. The NFN and FCM methods are designed to classify the image of N pixels among M classes and tested over many color images, and NFN has shown a better classification result than FCM [11]. Kumar et al. (2013) compared Artificial Neural Network (ANN), Fuzzy C-Mean (FCM) and Fuzzy Min-Max Neural network (FMNN) which is very effective and helpful in cancer diagnosis for its several advantages. The motive behind that the fault tolerance, flexibility, non linearity are the factors of artificial neural network. FCM provides finest findings for overlapped data set; data point may be connected with more than one cluster centre. Non-linear separability, soft and hard decision, less training time, online adaptation is the advantages of FMNN. The classification methods are applied to both FMN and FCM on the X-ray 130 cancerous and noncancerous datasets available. Hence using FCM and FMNN to diagnose lung cancer is good[12]. Jaffer et al. (2009) proposed a method by using Fuzzy c-mean (FCM) and morphological techniques for detection of tumor from lung computed tomography (CT) images. Initially, the automated segmentation of lungs has been done using fuzzy. Region of interests (ROIs) have been extracted by using 8 directional searches slice by slice and then 3D ROI image have been constructed. A 3D template has been constructed and convolves with the 3D ROI image. Finally FCM have been used to extract ROI that contain nodule. The technique was tested against the 50 datasets of different patients received from Aga Khan Medical University, Pakistan and Lung Image Database Consortium (LIDC) dataset [22]. Patel et al. (2010) developed an adaptive k means clustering algorithm for mammographic images segmentation for detection of breast cancer at early stage. The feature extraction is performed with the data base of 150 breast cancer images taken from BSR
  • 2. International Journal on Recent and Innovation Trends in Computing and Communication ISSN: 2321-8169 Volume: 5 Issue: 11 184 – 187 _______________________________________________________________________________________________ 185 IJRITCC | November 2017, Available @ http://www.ijritcc.org _______________________________________________________________________________________ APPOL with the parameter such as number, color and shape of object[23]. Fatma et al. (2011) presented Hopfield Neural Network (HNN) and a Fuzzy c-mean (FCM) clustering algorithm, for segmenting sputum color images for detection of lung cancer in early stages. The above methods are designed to classify the image of N pixels among M classes. They used 1000 sputum color images to test both methods, and HNN has shown a better classification result than FCM, the HNN succeeded in extracting the nuclei and cytoplasm regions [33]. Kaur et al. (2015) reviewed two methods i.e. Neural Network (NN) and Fuzzy c-mean Clustering Algorithm for sputum color images for early diagnose of lung cancer. They compared these two methods with their advantage and disadvantage and conclude that Fuzzy c-mean (FCM) clustering algorithm is not good at low intensity variations [35]. II. PROPOSED METHODOLOGY The proposed method follows several steps which include taking input image for pre processing for removal of noise and enhance the contrast of input image for better segmentation Fig. 1: Flow diagram of proposed system using various clustering techniques such as K-means and Fuzzy c-means. To find out accurate mass region process such as binary, dilation, erosion, opening and closing are performed step by step on each image. Finally, evaluate parameter like area, diameter and perimeter for comparison of better method. The flow diagram of proposed system has shown in Fig. 1. III. RESULTS AND DISCUSSION In this work we have compared two clustering techniques K- means and FCM for better lung mass segmentation in CT images that are used in CAD system. Both the methods are compared with several morphological operation and from the Fig. 2 it has been notice that the K-means techniques gives little bit smooth rounding edges for suspected nodule whereas FCM bordered more accurately because cancer nodule has not any specific size and somehow in zigzag pattern. The parameter such as area, perimeter and diameter calculated by FCM are more accurate as compare to K-means for each nodule. These parameters calculating by K-means is lesser due to smooth surfacing in nodule but FCM calculate these parameter values for each nodule efficiently which helps to further classify the nodule for T staging. Both the techniques gives prominent result but FCM is better for marking proper suspected area in case of single and multiple nodule detection in CT image of lung The comparative study of K-means and Fuzzy c-means algorithms in terms of several parameters such as area, diameter and perimeter has been evaluated. Experimental data have been consisting of more than 50 images and comparative results of 6 images are shown in Table 1. Table 1: Comparison of Segmentation Techniques Image No. Parameter K-means (pixel) FCM (pixel) cp1 Area 1839 1891 Perimeter 162.8 182.5 Diameter 48.4 49.1 cp2 Area 919 938 Perimeter 114.3 116.1 Diameter 34.4 34.6 cp3 Area 507 513 Perimeter 91.3 89.6 Diameter 25.4 25.6 cp4 Area 245 277 Perimeter 55.7 59.7 Diameter 17.7 18.8 cp5 Area 521 532 Perimeter 90.1 94.3 Diameter 25.8 26 cp6 Area 914 918 Perimeter 190.5 189.3 Diameter 34.1 34.2 Read the CT Image of Lung to be Segmented and Classified Start Apply Pre Processing: i) Noise Removal ii) Contrast Enhancement Apply Image Clustering Techniques ( k-means and Fuzzy c- means) Apply Morphological Processing i) Dilation and Erosion ii) Opening and Closing Calculate Various Suspected Region with Parameter: i) Area ii) Perimeter iii) Diameter Stop
  • 3. International Journal on Recent and Innovation Trends in Computing and Communication ISSN: 2321-8169 Volume: 5 Issue: 11 184 – 187 _______________________________________________________________________________________________ 186 IJRITCC | November 2017, Available @ http://www.ijritcc.org _______________________________________________________________________________________ (a) (e) (b) (f) (c) (g) (d) (h) Fig. 2 Result of K-means (a) Original image (b) Region of Interest (c) Binary image (d) Segmented Image Result of FCM (e) Original image (f)Region of Interest (g) Binary image (h) Segmented Image IV. CONCLUSION This work presents the better CAD system for automatic detection of lung nodule using segmentation techniques like k- means and fuzzy c-means (FCM) and carried out with some morphological operation for proper extraction of affected lung area. These algorithms tested over 50 images and found FCM is better than k-means in all respect for efficient detection of mass region inside lung CT images. REFERENCES [1] Farag, A., El-Baz , A., Gimel farb, G. and Falk, R., (2004), Detection and Recognition of Lung Abnormalities Using Deformable Templates, IEEE Proceedings of the 17th International Conference on Pattern Recognition. [2] El-Bazl, A., Farag, A., Falk, R. and Rocca, R., (2003), Automatic Identification of Lung Abnormalities in Chest Spiral CT Scans, IEEE International conference on Acoustics, Speech and Signal Processing, pp 261-264. [3] Hashmi, A., Pilewar, A. H. and Rafeh, R., (2013), Mass Detection in Lung CT Images Using Region Growing Segmentation and Decision Making Based on Fuzzy Inference System and Artificial Neural Network, International Journal on Image, Graphics and Signal Processing, Vol. 6, pp 16-24. [4] Wang, W. and Wu, S., (2006), A Study on Lung Cancer Detection by Image Processing, IEEE Proceeding, pp 371- 374. [5] Judice, A., Geetha, K. P. and Thampi, R. K., (2013), Modified approaches on Lung Cancer Cell Extraction and Classification from Computerized Tomography Images, Life Science Journal, 10(2), pp 1621-1626. [6] Volpi, S. L., Antonelli, M. and Stefanescu, D. C., (2009), Segmentation and reconstruction of the lung and the mediastinum volumes in CT images, IEEE Conference Proceeding. [7] Niki, N., Kanazawa, K., Satoh, H., Ohmatsu, H. and Moriyama, N., (1995), Computer Assisted Diagnosis of Lung Cancer Using Helical X-ray CT, IEEE Nuclear Science Symposium and Medical Imaging Conference , pp 1475-1479. [8] Deep, G., Kaur L. and Gupta S., (2013), Lung Nodule Segmentation in CT Images using Rotation Invarient Local Binary Pattern, ACEEE International Journal on Signal and Image Processing, pp 20-23. [9] Maivizhi, A. and Kalaiselvi, C., (2013), Cancer Gene Identification Using Fuzzy C- means Algorithm, Journal of Environmental Science ,Computer Science and Engineering and Technology, Vol. 3, No. 1, pp 157-164. [10] El-Baz, A., Gimel farb, G., Falk, R. and Abo El-Ghar, M., (2007), A New Cad System for Early Diagnosis Of Detected Lung Nodules, IEEE Conference Proceeding, pp 461-464. [11] Niranjana, C. M., Dhananandhini, J., Rajeswari, K. and Dhivya, A., (2014), A New Approches of Lung Segmentation Using Neuro-Fuzzy Network, International Journal of Soft Computing and Engineering, Vol. 3, Issue 6, pp 52-54. [12] Kumar, V., Garg, K. and Kher, V., (2013), Early Diagnosis of Lung Cancer with ANN, FCM and FMNN, International Journal of Advanced Research in Computer Science and Software Engineering,Vol. 3, Issue 12, pp 378-384. [13] Jaffer, M. A., Hussain, A. and Mirza, A. M., (2010), Fuzzy entropy based optimization of clusters for the segmentation of lungs in CT scanned images, Springer, pp 91-111. [14] Zhu Wang, Q., Wang, K., Guo, Y. and Wang, X., (2010), Automatic Detection of Pulmonary Nodules in Multi-slice CT Based on 3D Neural Networks With adaptive Initial Weights, International Conference on Intelligent Computation Technology and Automation, IEEE proceeding, pp 833-836.
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