Demography is the science involved with the study of biological population. It is also general science that can be suited to any kind of dynamic population study involving changes over time or space. It involves the study of the size, structure, and distribution of populations and spatial and or temporal changes in them in response to birth, death, migration and aging.
Characteristics of Population PPT covers all the types of Age Distribution Methods,Growth Rates,Population Density,Gender Ratio,Pattern of Distribution ,etc.
Introduction:
Life table:
Life table is a comprehensive method of describing mortality, survival and other vital events in a population.
It is composed of several sets of values showing how a group of infants who are under unchanging conditions would gradually die.
It provides concise measures of longevity of that population.
Separate tables are prepared for males and females after each decennium census.
It is also called as the “Biometer” of the population by William Farr.
Characteristics of Population PPT covers all the types of Age Distribution Methods,Growth Rates,Population Density,Gender Ratio,Pattern of Distribution ,etc.
Introduction:
Life table:
Life table is a comprehensive method of describing mortality, survival and other vital events in a population.
It is composed of several sets of values showing how a group of infants who are under unchanging conditions would gradually die.
It provides concise measures of longevity of that population.
Separate tables are prepared for males and females after each decennium census.
It is also called as the “Biometer” of the population by William Farr.
Exponential growth: Resource (food and space) availability is
obviously essential for the unimpeded growth of a population.
Ideally, when resources in the habitat are unlimited, each species
has the ability to realise fully its innate potential to grow in number,
as Darwin observed while developing his theory of natural
selection.
Exponential growth: Resource (food and space) availability is
obviously essential for the unimpeded growth of a population.
Ideally, when resources in the habitat are unlimited, each species
has the ability to realise fully its innate potential to grow in number,
as Darwin observed while developing his theory of natural
selection.
The surface of the earth is divided into four inter-connected spheres called "geo-spheres". These are the lithosphere, hydrosphere, biosphere, and atmosphere. Geologists, scientists and researchers discovered and classified life and material on or near the surface of the earth in these four spheres. The four spheres derived its names from the Greek words litho for stone, atmo for air, hydro for water and bio for life.
Newton’s laws of motion are part of physics which is a branch of science that we often ignore in our everyday lives. These laws deal with how objects move when force is applied to them. Newton’s laws of motion have been considered in the manufacture of cars and their safety.
"Solving the climate crisis is within our grasp, but we need people like you to STAND UP AND ACT."
AL GORE
Founder and Chairman,
The Climate Reality Project
A projectile is an object upon which the only force acting is gravity. There are many examples of projectiles. An object dropped from rest is a projectile as long as that the influence of air resistance is negligible. An object that is thrown vertically upward is also a projectile provided that the influence of air resistance is negligible. And an object which is thrown upward at an angle to the horizontal is also a projectile as long as that the influence of air resistance is negligible. A projectile is any object that once projected or dropped continues in motion by its own inertia and is influenced only by the downward force of gravity.
Astronomy is known as the science of the entire universe beyond the Earth. It includes the Earth’s gross physical properties: its mass and rotation, as they interact with other bodies of the solar system.
Periodic Table is the tabular arrangement of all the chemical elements which are organized based on atomic numbers, electronic configurations and existing chemical properties.
The Continental Drift Theory, The Seafloor Spreading Theory and The Plate Tectonics Theory are the three important theories taking place in our planet.
"The incredible thing is that after that, efforts were not undertaken to curb emissions of greenhouse gases, which are today, now that CFC emissions have been curtailed, the main cause of the destruction of ozone worldwide."-Bedrich Magas
Introduction organisms and populations class 12
Ecology is the scientific study of the interactions among organisms and their environment, encompassing a diverse array of living and non-living components. In the context of Class 12 Biology, the study of ecology specifically delves into the intricate relationships between organisms and populations. This branch of biology seeks to unravel the dynamics of life at both individual and collective levels, exploring how organisms adapt to their surroundings and influence one another in the grand tapestry of ecosystems. By investigating topics such as population ecology, community dynamics, and the delicate balance of ecosystems, students gain insights into the mechanisms governing life on Earth. Understanding these ecological principles is fundamental not only to appreciating the complexities of the natural world but also to addressing contemporary challenges related to biodiversity conservation, environmental sustainability, and the impact of human activities on ecosystems. Through the lens of ecology, students in Class 12 embark on a journey to comprehend the interconnected web of life and the factors shaping the diversity, distribution, and interactions of organisms and populations in their ever-changing environments.
For more information, visit. www.vavaclasses.com
A population is generally a group of particular species occupying a particular area at a specific time. Some of the ecologists however recognize two types of population;
Monospecific population- a population with individuals only one species
Mixed or Polyspecific population- a population of more than one species
However in Ecology, a polyspecific population is considered as a COMMUNITY, and the term POPULATION is used for a group of individuals of any kind of organism.
POPULATION ECOLOGY is the study of individuals of the same species where the processes are aggregation, interdependencies between individuals etc, and the various factors governing such processes are emphasized.
Dynamic biological process influence population density, dispersion a.pdfellanorfelicityri239
Dynamic biological process influence population density, dispersion and demographics
Distinguish between density and dispersion of population. Describe conditions that may result in
clumped dispersion, uniform dispersion, and random dispersion of individuals in a population.
What is a life table and why is it a useful tool for ecologists interested in population ecology?
Distinguish between a life table and a reproductive table. What does a reproductive table tell us?
Describe the characteristics of populations that exhibit Type I, Type II, and Type III survivorship
curves. Could you draw the expected survivorship curve if you were given characteristics of the
population? The exponential model describes population growth in an idealized, unlimited
environment and the elastic model describes how a population grows more slowly as it nears its
carrying capacity. Compare the exponential model of population growth with the logistic model.
What expectations do we have about exponential growth in natural populations? Under what
conditions might we expect to see natural populations increase exponentially? What can
modeling an organism\'s capacity to grow exponentially tell us about it? Explain how an
environment\'s carrying capacity affects the per capita rate of increase of a population. Explain
the meaning of each of the following terms in the logistics model of population growth: dN/dt,
t_max, K N, and (K - N)/K? Distinguish between r-selected populations and K-selected
populations Life history traits are products of natural selection What are life history traits?
What defines an organisms life history? Define and distinguish between semelparity and
iteroparity. Explain what factors may favor the evolution of each life history strategy.
Solution
Density of a population means the number of individuals present in one unit area. Dispersion
means in what manner they are dispersed or spread out in that area whether randomly distributed,
or in groups or evenly dispersed. In clumped dispersion,animals make groups to move and live
together. Often when there is shortage and scarcity of resources in summers, animals tend to
make groups to share resources.These groups can be safeguards for juveniles and can protect
them. Preying skills of few animals can benefit rest of the group in getting the food. In Uniform
dispersion all the animals are evenly distributed on the area and mostly independent to prey and
fight for their own food. They find mate according to their own choice and compatibility and
protect themselves alone. In random dispersion, the population is distributed randomly in the
area where there is mix of all three dispersion patterns. There is enough food in the viscinity,
animals can roam and search freely their food and also can form group. Life table is a table that
has data about death and birth rates of a population under study, that can give ecologists
prediction about probable growth or shrink of a population. It gives them the pattern of .
Ppt is made vailable for public for scientifc use.
Population ecology concept and its characteristics explained by using practical examples in a simple language. data is significant for competitive examinations
Population ecology is a field of scientific research that examines the dynamics of populations of living organisms within a given environment. It involves the study of various aspects of populations, including their growth, distribution, density, age structure, and the factors that affect these attributes. Key components of population ecology include:
Population Dynamics: Population ecologists study how the size of a population changes over time. This involves examining birth rates (natality), death rates (mortality), immigration, and emigration.
Population Distribution: Understanding how individuals in a population are spatially distributed is essential. Populations can be clumped, evenly dispersed, or randomly distributed in a habitat.
Population Density: This refers to the number of individuals of a species per unit area or volume of habitat. Population density can have significant ecological and environmental implications.
Age Structure: The age distribution within a population can provide insights into its growth potential and reproductive capacity. It can help in predicting future population trends.
Population Growth Models: Population ecologists use mathematical models to describe and predict population growth, such as exponential and logistic growth models.
Limiting Factors: Population growth is limited by various factors, including availability of resources, predation, competition, disease, and environmental conditions. Population ecologists study how these factors influence population dynamics.
Carrying Capacity: The carrying capacity of an environment is the maximum population size that can be sustained by available resources without causing environmental degradation or resource depletion.
Interactions: Populations do not exist in isolation. Interactions with other species, such as predation, competition, and mutualism, are essential considerations in population ecology.
Conservation and Management: Population ecology plays a critical role in the conservation and management of endangered species and ecosystems. It helps in making informed decisions to protect and sustainably manage populations.
Research Methods: Population ecologists employ various field and laboratory techniques, including population censuses, mark and recapture studies, and modeling, to gather data and understand population dynamics.
Second-level Digital Divide and experiences of Schools and TeachersLiwayway Memije-Cruz
The second-level digital divide, is referred to as the production gap, and it describes the gap that separates the consumers of content on the Internet from the producers of content.
Science and technology studies, or science, technology and society studies (STS) is the study of how society, politics, and culture affect scientific research and technological innovation, and how these, in turn, affect society, politics and culture.
A hydrocarbon is a molecule whose structure includes only hydrogen and carbon atoms. Hydrocarbons form bonds with other atoms in order to create organic compounds.
Hydrocarbon derivatives are based on simple hydrocarbon compounds that contain only hydrogens and carbons. Hydrocarbon derivatives contain at least one element other than hydrogen or carbon, such as oxygen, nitrogen or one of the halogen atoms (elements in column 7A of the Periodic Table.
Organic reactions are chemical reactions involving organic compounds. Organic reactions are used in the construction of new organic molecules. The production of many man-made chemicals such as drugs, plastics, food additives, fabrics depend on organic reactions.
Organic chemistry involves the study of the structure, properties, composition, reactions, and preparation of carbon-containing compounds, which include not only hydrocarbons but also compounds with any number of other elements, including hydrogen (most compounds contain at least one carbon–hydrogen bond), nitrogen, oxygen, halogens, phosphorus, silicon, and sulfur.
This branch of chemistry was originally limited to compounds produced by living organisms but has been broadened to include human-made substances such as plastics. The range of application of organic compounds is enormous and also includes, but is not limited to, pharmaceuticals, petrochemicals, food, explosives, paints, and cosmetics.
Organic chemistry is the study of the structure, properties, composition, reactions, and preparation of carbon-containing compounds, which include not only hydrocarbons but also compounds with any number of other elements, including hydrogen (most compounds contain at least one carbon–hydrogen bond), nitrogen, oxygen,
Science and technology studies, or science, technology and society studies (STS) is the study of how society, politics, and culture affect scientific research and technological innovation, and how these, in turn, affect society, politics and culture.
Isomers are molecules with the same molecular formula, but different structural or spatial arrangements of the atoms within the molecule. The reason there are such a colossal number of organic compounds which is more than 10 million is partly due to isomerism.
Apportionment is Apportionment involves dividing something up, just like fair division.
Voting is a method for a group, such as, a meeting or an electorate to make a collective decision or express an opinion, usually following discussions, debates or election campaigns.
Lipid metabolism entails the oxidation of fatty acids to either generate energy or synthesize new lipids from smaller constituent molecules. Lipid metabolism is associated with carbohydrate metabolism, as products of glucose (such as acetyl CoA) can be converted into lipids.
A Hamiltonian path is a path that visits each vertex of the graph exactly once.
A Hamiltonian circuit is a path that uses each vertex of a graph exactly once and returns to the starting vertex.
Carbohydrate metabolism involves the different biochemical processes responsible for the formation, breakdown, and interconversion of carbohydrates in living organisms.
A graph is a diagram displaying data which show the relationship between two or more quantities, measurements or indicative numbers that may or may not have a specific mathematical formula relating them to each other.
Every organism is composed of several different types of human body tissue. The human body tissue is another way of describing how our cells are grouped together in a highly organized manner according to specific structure and function. These groupings of cells form tissues, which then make up organs and various parts of the body.
Reproduction means producing offspring that may or may not be exact copies of their parents. It is a part of a life cycle, which is a series of events wherein individuals grow, develop, and reproduce according to a program of instructions encoded in DNA, which they inherit from their parents. When cells divide, each daughter cell receives a complete copy of DNA and enough cytoplasmic machinery to start up its own operation. DNA contains the blueprints for making different proteins.
.Enzymes are proteins that catalyze or speed up chemical reactions. They also help digest the foods we eat food and heal our wounds. They play major roles in respiration, making proteins, and DNA replication..
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...Ana Luísa Pinho
Functional Magnetic Resonance Imaging (fMRI) provides means to characterize brain activations in response to behavior. However, cognitive neuroscience has been limited to group-level effects referring to the performance of specific tasks. To obtain the functional profile of elementary cognitive mechanisms, the combination of brain responses to many tasks is required. Yet, to date, both structural atlases and parcellation-based activations do not fully account for cognitive function and still present several limitations. Further, they do not adapt overall to individual characteristics. In this talk, I will give an account of deep-behavioral phenotyping strategies, namely data-driven methods in large task-fMRI datasets, to optimize functional brain-data collection and improve inference of effects-of-interest related to mental processes. Key to this approach is the employment of fast multi-functional paradigms rich on features that can be well parametrized and, consequently, facilitate the creation of psycho-physiological constructs to be modelled with imaging data. Particular emphasis will be given to music stimuli when studying high-order cognitive mechanisms, due to their ecological nature and quality to enable complex behavior compounded by discrete entities. I will also discuss how deep-behavioral phenotyping and individualized models applied to neuroimaging data can better account for the subject-specific organization of domain-general cognitive systems in the human brain. Finally, the accumulation of functional brain signatures brings the possibility to clarify relationships among tasks and create a univocal link between brain systems and mental functions through: (1) the development of ontologies proposing an organization of cognitive processes; and (2) brain-network taxonomies describing functional specialization. To this end, tools to improve commensurability in cognitive science are necessary, such as public repositories, ontology-based platforms and automated meta-analysis tools. I will thus discuss some brain-atlasing resources currently under development, and their applicability in cognitive as well as clinical neuroscience.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...University of Maribor
Slides from:
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Track: Artificial Intelligence
https://www.etran.rs/2024/en/home-english/
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
What is greenhouse gasses and how many gasses are there to affect the Earth.moosaasad1975
What are greenhouse gasses how they affect the earth and its environment what is the future of the environment and earth how the weather and the climate effects.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
4. Ecological Niche
the role and position
a species has in its
environment
it is how it meets its
needs for food and
shelter, how it
survives, and how it
reproduces.
5. Demography
the scientific study ofthe scientific study of
biological populationbiological population
a general science that cana general science that can
be applied to any kind ofbe applied to any kind of
dynamic population that isdynamic population that is
one that changes over timeone that changes over time
or space.or space.
encompasses the study ofencompasses the study of
the size, structure, andthe size, structure, and
distribution of populationsdistribution of populations
and spatial and or temporaland spatial and or temporal
changes in them in responsechanges in them in response
to birth, death, migration andto birth, death, migration and
ageing.ageing.
6. Population
sum of all the
organisms of the
same group or
species, which live in
a particular
geographical area,
and have the
capability of
reproduction.
10. Natality or Birth Rate
the greatest factor that
influences population
increase.
the inherent ability of
population to increase.
Maximum natality - the
absolute or theoretical
maximum production of new
individual under ideal
condition.
Ecological natality - the
population increase under
actual or environmental
conditions.
11. Mortality or Death Rate
usually expressed as
the probability of
dying.
Minimum Mortality is
the loss of the
individual ideal
condition. Ecological
Mortality is the loss
of individual under
given environment.
12. Immigration
the movement of people
into a destination country
to which they are not
native or do not possess
its citizenship in order to
settle or reside there, as
permanent residents or
naturalized citizens, or to
take-up employment as a
migrant worker or
temporarily as a foreign
worker.
13. Emigration
act of leaving one's resident country with the intent to
settle elsewhere
15. Logistic Growth
As a population increases in size, the same resources must be
shared by a greater and greater number of individuals. The
decreasing supply of resources may lower the birth rate, increase
the birth rate or both, thus population growth declines with
increasing density, eventually reaching a level at which population
growth ceases. The level is called carrying capacity and is
expressed as K of the environment. A sustainable supply of
sources including nutrients, energy and living spaces defines the
carrying capacity for a particular environment.
Its rate of increase is low at first then accelerates and slows again,
then levels of as the carrying capacity of the environment is
reached. A plot of this growth pattern gives as a sigmoid or S-
shaped curve.
16. Exponential Growth
Population exhibit characteristic patterns
of increase known as population growth
forms.
Exponential growth is a pattern of growth
wherein the variables affect population
size and can be measured either for the
entire population or per individual.
21. Chief Seattle’s quote
What ever befalls the earth?
Befalls the sons and daughters of the earth…
We did not weave the web of life;
We are merely a strand in it.
Whatever we do to the web,
we do to ourselves