INTRODUCTION DEFINITION HISTORY NANOSCALE NANOPARTICLES NANOBIOTECHNOLOGY NANOTOOLS APPLICATIONS RESEARCH CONCLUSION REFRENCES Nanotechnology is the design, characterization and application of structures, devices and systems by controlling shape and size at the nanometer scale!” defines the Royal Academy of Engineering in London in 2004 . Concepts that are enhanced through nanobiology include: nanodevices, nanoparticles, and nanoscale phenomena that occurs within the discipline of nanotechnology.

1. “APPLICATIONS OF
NANOBIOTECHNOLOGY”
By
KAUSHAL KUMAR SAHU
Assistant Professor (Ad Hoc)
Department of Biotechnology
Govt. Digvijay Autonomous P. G. College
Raj-Nandgaon ( C. G. )

2.  INTRODUCTION
 DEFINITION
 HISTORY
 NANOSCALE
 NANOPARTICLES
 NANOBIOTECHNOLOGY
 NANOTOOLS
 APPLICATIONS
 RESEARCH
 CONCLUSION
 REFRENCES
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3.  Nanotechnology is the design, characterization
and application of structures, devices and
systems by controlling shape and size at the
nanometer scale!” defines the Royal Academy of
Engineering in London in 2004 .
 Concepts that are enhanced through nanobiology
include: nanodevices, nanoparticles, and
nanoscale phenomena that occurs within the
discipline of nanotechnology.
INTRODUCTION

4. Nanobiotechnology
 is used to create devices to study biological system.
 Examples :- nanoparticles as delivery systems or as sensors.
Bionanotechnology
 involve working with biomolecules on the nanoscale.
 miniaturized biotechnology.
 Examples :-DNA nano tecchnology or cellular engineering
DEFINITION

9.  ENHANCING BATTERY POWER
Silicon nanoparticles coating anodes of lithium-
ion batteries to increase battery power and reduce
recharge time.
 PROTECTION FROM UV RADIATION(ZnO2)
 IMPROVING FABRIC QUALITY
Silver nanoparticles in fabric that kills bacteria
and making cloth odor-resistant.
 PREVENTING FOOD SPOILAGE
Silicate nanoparticles used to provide a barrier to
gasses O2 or moisture in a plastic film used for
packaging.
SOME NANOTECHNOLOGY
APPLICATIONS

10. WHAT IS NANOBIOTECHNOLOGY ?

11. APPLICATION OF NANOBIOTECHNOLOGY

12.  NANOROBOTS
 NANOSHELL
 QUANTUM DOTS
 DENDRIMERS
 CARBON NANOTUBE
 NANOWIRE SENSORS
 LIPOSOMES
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13.  Nanobots, nanoids, nanites or
nanomites .
 Size from 0.1–10 micrometers .
 Diagnosis and targeted drug-
delivery for cancer, biomedical
instrumentation surgery,
monitoring of diabetes and health
care.
NANOROBOTS FOR NANOMEDICINE

14. DNA NANOTECHNOLOGY
 DNA nanotechnology is the design and manufacture
of artificial nucleic acid structures for technological
uses.
NUBOTS
 “Nuclic Acid Robots.”
 DNA test and blood cell detection.

15. LIPOSOMES

16. Nanoshell
White
blood cell
Water
molecule
Nanodevices
Nanoshells
Gold
Near-infrared light onNear-infrared light off
Nanoshell absorbs heat
NANOSHELL

18. QUANTAM DOTS:WHAT ARE THEY?
 Fluorescent
nanocrystals.
 Common QDs: CdS,
CdSe, PbS, PbSe,
PbTd, CuCl

19. Quantum Dots
Ultraviolet
light off
White
blood cell
Water
molecule
Nanodevices
Quantum dots
Quantum dots
emit light
Ultraviolet
light on
Quantum
dots
Quantum dot
bead

20. Quantum Dots Can
Find Cancer Signatures
Cancer cells
Healthy cells
Quantum dot beads
Quantum dot beads
Healthy cells
Cancer cells

21. Dendrimers
Dendrimer
White
blood cell
Water
molecule
Nanodevices
Dendrimer
Cancer cell

22. Antibody-dendrimer conjugates for
diagnosis of HIV-1 and cancer
Medical applications ( MRI contrast
enhancer)
Vehicles for delivery of genes and drugs
Dendrimers Applications

23. Dendrimers as Cancer Therapy
Cell death
monitor
Reporter
Therapeutic
agent
Cancer
detector
Water
molecule
White
blood cell
Nanodevices
Dendrimer

24. Improving Cancer Treatment
Nanotechnology TreatmentTraditional Treatment
Intact noncancerous cells
Noncancerous cells
Toxins Nanodevices
Cancer
cells
Dead noncancerous cells
Noncancerous cells
Drugs
Dead
cancer
cells
Dead
cancer
cells
Toxins
Cancer
cells

25. TISSUE ENGINEERING

26. CARBAN NANOTUBES
 CNT is a tubular form of carbon
with diameter as small as 1 nm
 Carbon nano tubes are being used
for drug delivery and cancer
detection.
carbon nanotubes

28. IMPROVING MRI IMAGING
o Iron oxide nanoparticles can used to improve MRI
images of cancer tumors.
o The nanoparticle is coated with a peptide that
binds to a cancer tumor, once the nanoparticles are
attached to the tumor the magnetic property of the
iron oxide enhances the images from the Magnetic
Resonance Imagining scan.

29. TARGETED DRUG DELIVERY
 Nanoparticles containing drugs are coated with
targeting agents (e.g. conjugated antibodies) it
circulate through the blood vessels and reach the
target cells.

30. IMPACT OF NANOMATERIALS

31.  A nematode-trapping fungus, Arthrobotrys
oligospora, spherical nanoparticles which contains
glycosaminoglycan and protein components which
act as immuno- stimulatory and antitumor agent
for cancer immuno chemotherapy.
( Image: Dr. Zhang, The University of Tennessee)
( Dec 18 , 2012 )
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33. REFERENCES
Journals & Articles:-
• Peter HM Hoet, Irene Brüske-Hohlfeld and Oleg V Salata, Nanoparticles -
Known and unknown health risks ,Journal of biotechnology, 2004.
• Robert S. Langer, An article on Nanobiotechnology, Drug delivery and
tissue engineering.
Books:-
• Nanophysics and Nanotechnology, Edward L. Wolf, Second Edition.
Citation:-
• http://emri.tums.ac.ir
• www.sciencecenter.org
• www.nbtc.cornell.edu
REFERENCES