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Treatment of
Bradycardia
Dan Stevens
Types of Bradycardia
 Sinus
• Drugs
• Athletes
• Increased Vagal tone
 Sick Sinus syndrome
• SA node disease
 Sinus puase / arrest, Tachy-brady syndrome
 Atrioventricular
• 1st Degree
• 2nd degree
 Mobitz I (wenchebach), Mobitz II
• 3rd Degree
 Complete HB
Causes
 Ischaemic / infarction related
 Neurocardiogenic – reflex mediated
 Toxicology
• Ca channel blockers, B-blockers
 Metabolic
• Hyperkalaemia
 Endocrine
• Hypothyroidism
 Environmental
• Hypothermia
 Infections with cardiac involvement
• Lyme Disease
• Chagas disease
Treatment Options
 Treat Cause
 Stable Vs Unstable
 Do Nothing
 Medications
 Transcutaneous Pacing
 Pacing Wire / PPM
Evidence For Treatment??
 Not much
 Difficult patient group to study
 Guidelines based on expert opinion
Drugs
 Atropine
• Competitive antagonist of acetylcholine at
muscarinic receptors
• Increased HR (by reducing vagal tone)
• 400mcg up to 3mg
• Useful in vagally mediated bradycardia or
possibly very high blocks
• Often no use in complete HB
Drugs
 Adrenaline (preferred chronotrope)
• Non selective alpha and B agonist
• Increased blood pressure and HR
• 2-10 mcg/min
 Isoprenaline
• Selective, potent B agonist (B1)
• Risk of hypotension (No alpha effect & B2
agonist)
• Positive inotrope, positive chronotrope
• 1-4 mcg/min
 Dopamine
• 2-10 mcg/kg/min
Transcutaneous Pacing
 Place pads in AP position
 Connect ECG leads
 Set Defibrillator to Pacing mode
 Set rate (>30bpm than currently, normally 70)
 Sedation!!
 Start pacing and increase current until ‘capture’
• Electrical capture  QRS and T wave after each pacing
spike
• Mechanical capture  central pulse
 Current fixed at 10 mA (or ~20%) above level of capture
 If reach 130mA and no capture try changing paddle
position
Cardiology
 Temporary Pacing wires /
Transvenous Pacing
• Central venous access (right IJV)
• Catheter with pacing wire slowly
inserted until capture
 Permanent Pacemaker
Summary
 Investigate and treat cause
 Atropine up to 2mg (in selected pt’s)
 Adrenaline infusion
 Transcutaneous pacing
• Sedation
• Rate 70
• Current 10 mA (or ~20%) above level
of capture
 Early cardiology referral for
transvenous pacing wire / PPM

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Treatment of Bradycardia

  • 2. Types of Bradycardia  Sinus • Drugs • Athletes • Increased Vagal tone  Sick Sinus syndrome • SA node disease  Sinus puase / arrest, Tachy-brady syndrome  Atrioventricular • 1st Degree • 2nd degree  Mobitz I (wenchebach), Mobitz II • 3rd Degree  Complete HB
  • 3. Causes  Ischaemic / infarction related  Neurocardiogenic – reflex mediated  Toxicology • Ca channel blockers, B-blockers  Metabolic • Hyperkalaemia  Endocrine • Hypothyroidism  Environmental • Hypothermia  Infections with cardiac involvement • Lyme Disease • Chagas disease
  • 4. Treatment Options  Treat Cause  Stable Vs Unstable  Do Nothing  Medications  Transcutaneous Pacing  Pacing Wire / PPM
  • 5. Evidence For Treatment??  Not much  Difficult patient group to study  Guidelines based on expert opinion
  • 6. Drugs  Atropine • Competitive antagonist of acetylcholine at muscarinic receptors • Increased HR (by reducing vagal tone) • 400mcg up to 3mg • Useful in vagally mediated bradycardia or possibly very high blocks • Often no use in complete HB
  • 7. Drugs  Adrenaline (preferred chronotrope) • Non selective alpha and B agonist • Increased blood pressure and HR • 2-10 mcg/min  Isoprenaline • Selective, potent B agonist (B1) • Risk of hypotension (No alpha effect & B2 agonist) • Positive inotrope, positive chronotrope • 1-4 mcg/min  Dopamine • 2-10 mcg/kg/min
  • 8. Transcutaneous Pacing  Place pads in AP position  Connect ECG leads  Set Defibrillator to Pacing mode  Set rate (>30bpm than currently, normally 70)  Sedation!!  Start pacing and increase current until ‘capture’ • Electrical capture  QRS and T wave after each pacing spike • Mechanical capture  central pulse  Current fixed at 10 mA (or ~20%) above level of capture  If reach 130mA and no capture try changing paddle position
  • 9. Cardiology  Temporary Pacing wires / Transvenous Pacing • Central venous access (right IJV) • Catheter with pacing wire slowly inserted until capture  Permanent Pacemaker
  • 10. Summary  Investigate and treat cause  Atropine up to 2mg (in selected pt’s)  Adrenaline infusion  Transcutaneous pacing • Sedation • Rate 70 • Current 10 mA (or ~20%) above level of capture  Early cardiology referral for transvenous pacing wire / PPM