Thermodynamics is the branch of physics that studies the effects of temperature, pressure, and volume changes on systems using statistics and particle motion analysis. It examines how energy moves and causes movement. The first law of thermodynamics states that energy is conserved; the second law is about entropy and how the entropy of isolated systems increases over time. The third law indicates that entropy reaches its minimum at absolute zero temperature. The human mind's design reflects the second law's influence, as its problem-solving logic evolved to cope with entropy constraints.
this is my presentation about 2nd law of thermodynamic. this is part of engineering thermodynamic in mechanical engineering. here discussed about heat transfer, heat engines, thermal efficiency of heat pumps and refrigerator and its equation for perfect work done with best figure and table wise discription, entropy and change in entropy, isentropic process for turbines and compressor and many more.
this is my presentation about 2nd law of thermodynamic. this is part of engineering thermodynamic in mechanical engineering. here discussed about heat transfer, heat engines, thermal efficiency of heat pumps and refrigerator and its equation for perfect work done with best figure and table wise discription, entropy and change in entropy, isentropic process for turbines and compressor and many more.
the branch of physical science that deals with the relations between heat and other forms of energy (such as mechanical, electrical, or chemical energy), and, by extension, of the relationships between all forms of energy.
Introduction to the second law
Thermal energy reservoirs
Heat engines
Thermal efficiency
The 2nd law: Kelvin-Planck statement
Refrigerators and heat pumps
Coefficient of performance (COP)
The 2nd law: Clasius statement
Perpetual motion machines
Reversible and irreversible processes
Irreversibility's, Internal and externally reversible processes
The Carnot cycle
The reversed Carnot cycle
The Carnot principles
The thermodynamic temperature scale
The Carnot heat engine
The quality of energy
The Carnot refrigerator and heat pump
The following presentation consists of information on limitation of 1st law, introduction to 2nd law, kelvin planks statement, Clausius statement, PPM 2, Carnot cycle, Carnot heat engines, etc
What is greenhouse effect ?
Is greenhouse effect have a serious impact on human health?
What we have to do to reduce the greenhouse effect ?
This simple presentation helps to understand the basic facts about greenhouse effect.
the branch of physical science that deals with the relations between heat and other forms of energy (such as mechanical, electrical, or chemical energy), and, by extension, of the relationships between all forms of energy.
Introduction to the second law
Thermal energy reservoirs
Heat engines
Thermal efficiency
The 2nd law: Kelvin-Planck statement
Refrigerators and heat pumps
Coefficient of performance (COP)
The 2nd law: Clasius statement
Perpetual motion machines
Reversible and irreversible processes
Irreversibility's, Internal and externally reversible processes
The Carnot cycle
The reversed Carnot cycle
The Carnot principles
The thermodynamic temperature scale
The Carnot heat engine
The quality of energy
The Carnot refrigerator and heat pump
The following presentation consists of information on limitation of 1st law, introduction to 2nd law, kelvin planks statement, Clausius statement, PPM 2, Carnot cycle, Carnot heat engines, etc
What is greenhouse effect ?
Is greenhouse effect have a serious impact on human health?
What we have to do to reduce the greenhouse effect ?
This simple presentation helps to understand the basic facts about greenhouse effect.
Friction is known as the resistance to motion of one object moving relative to another. According to scientists it is the result of the electromagnetic attraction between charged particles in two touching surfaces.
A mixture forms when two or more substances are combined such that each substance retains its own chemical identity. Everywhere around us are made up of mixtures. We can see them in nature, along the surface of the earth, in the oceans and in the foods we eat. There are infinite numbers of mixtures that can be combined into homogeneous or heterogeneous.
Life substances are substances, which contain the life or food, which vivifies and sustains. But those who fail to receive these life-giving substances will, sooner or later, realize their necessity - Carlos Kozel
Periodic Table is the tabular arrangement of all the chemical elements which are organized based on atomic numbers, electronic configurations and existing chemical properties.
Chemistry is involved with various and diverse interactions of matter either around us or simply inside the laboratory. These are described using the language of chemistry which consists of symbols, formulas and equations.
Stoichiometry deals with the numerical relationships of elements and compounds and the mathematical proportions of reactants and products in chemical transformations
Light is a transverse, electromagnetic wave that can be seen by humans. The wave nature of light was first illustrated through experiments on diffraction and interference. Like all electromagnetic waves, light can travel through a vacuum. The transverse nature of light can be demonstrated through polarization.
The three main categories of chemical compounds are acids, bases and salts. These compounds are always part of our daily lives in terms of what we eat and use. The human body contains some very common acids like dilute hydrochloric acid in the stomach, which aids in digestion of food. If the contents of our stomach become too acidic, it results to a burning sensation in the stomach. Acids and bases also regulate metabolic activities in the human body through equilibrium processes. Acids contain hydrogen ions (H+). A base is a substance, which on dissolving in water yields hydroxyl ions (OH-) as the only negative ions. Salts are formed by the combination of an acid and base.
If all the elements are arranged in the order of their atomic weights, a periodic repetition of properties is obtained. This is expressed by the law of periodicity.— Dmitry Ivanovich Mendeleev
"Solving the climate crisis is within our grasp, but we need people like you to STAND UP AND ACT."
AL GORE
Founder and Chairman,
The Climate Reality Project
The surface of the earth is divided into four inter-connected spheres called "geo-spheres". These are the lithosphere, hydrosphere, biosphere, and atmosphere. Geologists, scientists and researchers discovered and classified life and material on or near the surface of the earth in these four spheres. The four spheres derived its names from the Greek words litho for stone, atmo for air, hydro for water and bio for life.
Newton’s laws of motion are part of physics which is a branch of science that we often ignore in our everyday lives. These laws deal with how objects move when force is applied to them. Newton’s laws of motion have been considered in the manufacture of cars and their safety.
Thermodynamics is the branch of physics that deals with the relationships between heat and other forms of energy. In particular, it describes how thermal energy is converted to and from other forms of energy and how it affects matter.
In this PPT have have covered
1. Basic thermodynamics definition
2. Thermodynamics law
3. Properties , cycle, Process
4. Derivation of the Process
5.Formula for the numericals.
This topic is use full for those students who want to study basic thermodynamics as a part of their University syllabus.
Most of the university having basic Mechanical engineering as a subject and in this subject Thermodynamics is a topic so by this PPT our aim is to give presentable knowledge of the subject
SCIENCE EXPLAINS THE CAUSES OF THE FINITUDE OF EVERYTHING.pdfFaga1939
This article aims to scientifically demonstrate that living beings and planets like the Earth, stars like the Sun and the Universe we live in will come to an end due to entropy because they will evolve over time to a state of disorder. Entropy is commonly associated with the degree of disorder in a system. The greater the disorder of a thermodynamic system, the greater its entropy. All forms of life have a net increase in entropy. To sustain life, it is necessary to transfer energy to the living being. If you fail to do so, the organism soon dies and always tends towards the destruction of the order it had, that is, towards disorder or an increase in entropy. Planet Earth increases its entropy due to the increased exploitation of its resources, deforestation, pollution, among other sources of degradation. The greater this degradation, the greater the entropy of the planet, which could reach such a high stage that life on Earth will no longer be possible. The Sun's death will occur when it is in an advanced phase of its life and all its fuel, hydrogen, is consumed. The thermal death of the Universe will occur when it reaches its state of maximum entropy (state of thermodynamic equilibrium) and darkness reigns in the Universe, marking its "death". Based on the above, all living beings, all planets, all stars and the Universe, which constitute thermodynamic systems, will end when their respective entropies reach the maximum value. To avoid the end of human beings as a species, it is necessary to make scientific and technological advances that ensure human life outside Earth and identify the existence of parallel universes to open the possibility for human beings to survive the end of our Universe by heading to parallel universes.
Entropy in physics, biology and in thermodynamicsjoshiblog
Entropy is a measure of probability and the "disorder" of a system.
Disorder refers to is really the number of different microscopic states a system can be in, given that the system has a particular fixed composition, volume, energy, pressure, and temperature.
the exact definition is
Entropy = (Boltzmann's constant k) x logarithm of number of possible states
= k log(N).
The first law of thermodynamics defines the relationship between the various forms of energy present in a system (kinetic and potential), the work which the system performs and the transfer of heat.
We can imagine thermodynamic processes which conserve energy but which never occur in nature.
For example, if we bring a hot object into contact with a cold object, we observe that the hot object cools down and the cold object heats up until an equilibrium is reached. The transfer of heat goes from the hot object to the cold object.
According to the second law of thermodynamics, in any process that involves a cycle, the entropy of the system will either stay the same or increase. When the cyclic process is reversible then the entropy will not change. When the process is irreversible, then entropy will increases.
The second law states that there exists a useful state variable called entropy S. The change in entropy delta S is equal to the heat transfer delta Q divided by the temperature T.
delta S = delta Q / T
Order can be produced with an expenditure of energy, and the order associated with life on the earth is produced with the aid of energy from the sun.
For example, plants use energy from the sun in tiny energy factories called chloroplasts Using chlorophyll in the process called photosynthesis, they convert the sun's energy into storable form in ordered sugar molecules. In this way, carbon and water in a more disordered state are combined to form the more ordered sugar molecules.
In animal systems there are also small structures within the cells called mitochondria which use the energy stored in sugar molecules from food to form more highly ordered structures.
thermodynamics. in physical world outside and inside the living body. important factor for heat and energy for the living.
different forms of energy, kinetic energy and pottential energy.
different forms of system, open and closed. laws of thermodynamics and gibbs free energy. entrophy and enthalphy
Thermodynamic laws describe the flows and interchanges of heat, energy and matter.
Almost all chemical and biochemical processes are as a result of transformation of energy.
Laws can provide important insights into metabolism and bioenergetics.
The energy exchanges between the system and the surroundings balance each other.
There is a hierarchy of energetics among organisms
Chemical energy stored by molecules can be released as heat
during chemical reactions when a fuel like methane, cooking
gas or coal burns in air. The chemical energy may also be
used to do mechanical work when a fuel burns in an engine
or to provide electrical energy through a galvanic cell like
dry cell. Thus, various forms of energy are interrelated and
under certain conditions, these may be transformed from
one form into another. The study of these energy
transformations forms the subject matter of thermodynamics.
The laws of thermodynamics deal with energy changes of
macroscopic systems involving a large number of molecules
rather than microscopic systems containing a few molecules.
Thermodynamics is not concerned about how and at what
rate these energy transformations are carried out, but is
based on initial and final states of a system undergoing the
change. Laws of thermodynamics apply only when a system
is in equilibrium or moves from one equilibrium state to
another equilibrium state.Chemical energy stored by molecules can be released as heat
during chemical reactions when a fuel like methane, cooking
gas or coal burns in air. The chemical energy may also be
used to do mechanical work when a fuel burns in an engine
or to provide electrical energy through a galvanic cell like
dry cell. Thus, various forms of energy are interrelated and
under certain conditions, these may be transformed from
one form into another. The study of these energy
transformations forms the subject matter of thermodynamics.
The laws of thermodynamics deal with energy changes of
macroscopic systems involving a large number of molecules
rather than microscopic systems containing a few molecules.
Thermodynamics is not concerned about how and at what
rate these energy transformations are carried out, but is
based on initial and final states of a system undergoing the
change. Laws of thermodynamics apply only when a system
is in equilibrium or moves from one equilibrium state to
another equilibrium state.Chemical energy stored by molecules can be released as heat
during chemical reactions when a fuel like methane, cooking
gas or coal burns in air. The chemical energy may also be
used to do mechanical work when a fuel burns in an engine
or to provide electrical energy through a galvanic cell like
dry cell. Thus, various forms of energy are interrelated and
under certain conditions, these may be transformed from
one form into another. The study of these energy
transformations forms the subject matter of thermodynamics.
The laws of thermodynamics deal with energy changes of
macroscopic systems involving a large number of molecules
rather than microscopic systems containing a few molecules.
Thermodynamics is not concerned about how and at what
rate these energy transformations are carried out, but is
based on initial and final states of a system undergoing the
change.
Second-level Digital Divide and experiences of Schools and TeachersLiwayway Memije-Cruz
The second-level digital divide, is referred to as the production gap, and it describes the gap that separates the consumers of content on the Internet from the producers of content.
Science and technology studies, or science, technology and society studies (STS) is the study of how society, politics, and culture affect scientific research and technological innovation, and how these, in turn, affect society, politics and culture.
A hydrocarbon is a molecule whose structure includes only hydrogen and carbon atoms. Hydrocarbons form bonds with other atoms in order to create organic compounds.
Hydrocarbon derivatives are based on simple hydrocarbon compounds that contain only hydrogens and carbons. Hydrocarbon derivatives contain at least one element other than hydrogen or carbon, such as oxygen, nitrogen or one of the halogen atoms (elements in column 7A of the Periodic Table.
Organic reactions are chemical reactions involving organic compounds. Organic reactions are used in the construction of new organic molecules. The production of many man-made chemicals such as drugs, plastics, food additives, fabrics depend on organic reactions.
Organic chemistry involves the study of the structure, properties, composition, reactions, and preparation of carbon-containing compounds, which include not only hydrocarbons but also compounds with any number of other elements, including hydrogen (most compounds contain at least one carbon–hydrogen bond), nitrogen, oxygen, halogens, phosphorus, silicon, and sulfur.
This branch of chemistry was originally limited to compounds produced by living organisms but has been broadened to include human-made substances such as plastics. The range of application of organic compounds is enormous and also includes, but is not limited to, pharmaceuticals, petrochemicals, food, explosives, paints, and cosmetics.
Organic chemistry is the study of the structure, properties, composition, reactions, and preparation of carbon-containing compounds, which include not only hydrocarbons but also compounds with any number of other elements, including hydrogen (most compounds contain at least one carbon–hydrogen bond), nitrogen, oxygen,
Science and technology studies, or science, technology and society studies (STS) is the study of how society, politics, and culture affect scientific research and technological innovation, and how these, in turn, affect society, politics and culture.
Isomers are molecules with the same molecular formula, but different structural or spatial arrangements of the atoms within the molecule. The reason there are such a colossal number of organic compounds which is more than 10 million is partly due to isomerism.
Apportionment is Apportionment involves dividing something up, just like fair division.
Voting is a method for a group, such as, a meeting or an electorate to make a collective decision or express an opinion, usually following discussions, debates or election campaigns.
Lipid metabolism entails the oxidation of fatty acids to either generate energy or synthesize new lipids from smaller constituent molecules. Lipid metabolism is associated with carbohydrate metabolism, as products of glucose (such as acetyl CoA) can be converted into lipids.
A Hamiltonian path is a path that visits each vertex of the graph exactly once.
A Hamiltonian circuit is a path that uses each vertex of a graph exactly once and returns to the starting vertex.
Carbohydrate metabolism involves the different biochemical processes responsible for the formation, breakdown, and interconversion of carbohydrates in living organisms.
A graph is a diagram displaying data which show the relationship between two or more quantities, measurements or indicative numbers that may or may not have a specific mathematical formula relating them to each other.
Every organism is composed of several different types of human body tissue. The human body tissue is another way of describing how our cells are grouped together in a highly organized manner according to specific structure and function. These groupings of cells form tissues, which then make up organs and various parts of the body.
Reproduction means producing offspring that may or may not be exact copies of their parents. It is a part of a life cycle, which is a series of events wherein individuals grow, develop, and reproduce according to a program of instructions encoded in DNA, which they inherit from their parents. When cells divide, each daughter cell receives a complete copy of DNA and enough cytoplasmic machinery to start up its own operation. DNA contains the blueprints for making different proteins.
.Enzymes are proteins that catalyze or speed up chemical reactions. They also help digest the foods we eat food and heal our wounds. They play major roles in respiration, making proteins, and DNA replication..
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
The increased availability of biomedical data, particularly in the public domain, offers the opportunity to better understand human health and to develop effective therapeutics for a wide range of unmet medical needs. However, data scientists remain stymied by the fact that data remain hard to find and to productively reuse because data and their metadata i) are wholly inaccessible, ii) are in non-standard or incompatible representations, iii) do not conform to community standards, and iv) have unclear or highly restricted terms and conditions that preclude legitimate reuse. These limitations require a rethink on data can be made machine and AI-ready - the key motivation behind the FAIR Guiding Principles. Concurrently, while recent efforts have explored the use of deep learning to fuse disparate data into predictive models for a wide range of biomedical applications, these models often fail even when the correct answer is already known, and fail to explain individual predictions in terms that data scientists can appreciate. These limitations suggest that new methods to produce practical artificial intelligence are still needed.
In this talk, I will discuss our work in (1) building an integrative knowledge infrastructure to prepare FAIR and "AI-ready" data and services along with (2) neurosymbolic AI methods to improve the quality of predictions and to generate plausible explanations. Attention is given to standards, platforms, and methods to wrangle knowledge into simple, but effective semantic and latent representations, and to make these available into standards-compliant and discoverable interfaces that can be used in model building, validation, and explanation. Our work, and those of others in the field, creates a baseline for building trustworthy and easy to deploy AI models in biomedicine.
Bio
Dr. Michel Dumontier is the Distinguished Professor of Data Science at Maastricht University, founder and executive director of the Institute of Data Science, and co-founder of the FAIR (Findable, Accessible, Interoperable and Reusable) data principles. His research explores socio-technological approaches for responsible discovery science, which includes collaborative multi-modal knowledge graphs, privacy-preserving distributed data mining, and AI methods for drug discovery and personalized medicine. His work is supported through the Dutch National Research Agenda, the Netherlands Organisation for Scientific Research, Horizon Europe, the European Open Science Cloud, the US National Institutes of Health, and a Marie-Curie Innovative Training Network. He is the editor-in-chief for the journal Data Science and is internationally recognized for his contributions in bioinformatics, biomedical informatics, and semantic technologies including ontologies and linked data.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
2. Thermodynamics
the branch of physics
involved with studies on the
effects of changes in
temperature, pressure, and
volume on physical systems
at the macroscopic scale.
It is done through the analysis
of the collective motion of
particles using statistics. The
motions produced by the
particles produce heat.
Heat in thermodynamics
means "energy in transit" and
dynamics relates to
"movement" Based on the
said principle,
thermodynamics studies the
movement of energy and how
energy instills movement
3. Thermodynamic System
heat moves from hot to cold and
work is extracted, through a
series of pistons. This is what we
call energy flow.
energy can be exchanged
between physical systems as
heat or work.
4. Trophic Level: Energy Flow
The steps
involved in the
flow of energy
through an
ecosystem.
the position that
an organism
occupies in a food
chain - what it
eats, and what
eats it.
5. Entropy
(on a macroscopic
scale) a function of
thermodynamic
variables, as
temperature,
pressure, or
composition, that is a
measure of the
energy that is not
available for work
during a
thermodynamic
8. Zeroth law of thermodynamics
states that
thermodynamic
equilibrium is an
equivalence
relation. If two
thermodynamic
systems are
separately in
thermal equilibrium
with a third, they are
also in thermal
equilibrium with
each other.
10. First law of thermodynamics
is about the
conservation of
energy.
The change in the
internal energy of a
closed
thermodynamic
system is equal to the
sum of the amount of
heat energy supplied
to the system and the
work done on the
11. Second law of thermodynamics
is about entropy.
The total
entropy of any
isolated
thermodynamic
system tends to
increase over
time,
approaching a
12. The First Law of Psychology is the Second
Law of Thermodynamics: The Energetic
Evolutionary Model of the Mind and the
Generation of Human Psychological
Phenomena
By Peggy La Cerra, Center for Evolutionary Neuroscience, 1919
Meiners Road, Ojai, CA 93023, USA.
13. The second law of thermodynamics has
crafted the functional design of the human
intelligence system, and the psychological,
behavioral and cultural products of the human
mind faithfully reflect its influence. The
architectural design and underlying problem-
solving logic of the human behavioral
intelligence system is phylogenetically ancient
in its origins, a tried and true solution to the
constraints on life imposed by entropy.
14. Third law of thermodynamics
about absolute zero temperature As a system asymptotically
approaches absolute zero of temperature all processes virtually
cease and the entropy of the system asymptotically approaches a
minimum value; also stated as: "the entropy of all systems and of
all states of a system is zero at absolute zero" or equivalently "it is
impossible to reach the absolute zero of temperature by any finite
number of processes".
it says that entropy at absolute zero is zero. Or in other words,
things are most orderly when they're really cold. Absolute zero is
the temperature at which molecules stop moving or vibrating at
all. Sounds pretty orderly to me! So the third law of
thermodynamics makes a lot of sense. This complete stop in
molecular motion happens at -273 Celsius, which is defined as 0
kelvin, or absolute zero.
17. The second law of thermodynamics has
crafted the functional design of the human
intelligence system, and the psychological,
behavioral and cultural products of the human
mind faithfully reflect its influence. The
architectural design and underlying problem-
solving logic of the human behavioral
intelligence system is phylogenetically ancient
in its origins, a tried and true solution to the
constraints on life imposed by entropy.