Stoichiometry deals with the numerical relationships of elements and compounds and the mathematical proportions of reactants and products in chemical transformations
The rate of reaction is the speed at which a reaction proceeds. The factors that affect the rate of a chemical reaction are : nature of reactants, temperature, concentration, size of particle and catalyst.
Quantum Numbers
Wave nature of electrons
atomic structure
principle Quantum number
Azimuthal quantum number
magnetic quantum number
spic quantum number
shapes of orbitals
This power point work describe about polar and nonn polar compounds and how to find it very easily and it also explain dipole moment and its calculation...this includes some workout problems
The rate of reaction is the speed at which a reaction proceeds. The factors that affect the rate of a chemical reaction are : nature of reactants, temperature, concentration, size of particle and catalyst.
Quantum Numbers
Wave nature of electrons
atomic structure
principle Quantum number
Azimuthal quantum number
magnetic quantum number
spic quantum number
shapes of orbitals
This power point work describe about polar and nonn polar compounds and how to find it very easily and it also explain dipole moment and its calculation...this includes some workout problems
Basics of Chemistry: Chemical stoichiometryRAJEEVBAYAN1
This material presents quantitative method of numerical measurements involved in a chemical reaction.
this involves quantities such as the measures of mass in grams and the amount of substance in moles.
I am hoping that this material will help to make the concept easier.
Second-level Digital Divide and experiences of Schools and TeachersLiwayway Memije-Cruz
The second-level digital divide, is referred to as the production gap, and it describes the gap that separates the consumers of content on the Internet from the producers of content.
Science and technology studies, or science, technology and society studies (STS) is the study of how society, politics, and culture affect scientific research and technological innovation, and how these, in turn, affect society, politics and culture.
A hydrocarbon is a molecule whose structure includes only hydrogen and carbon atoms. Hydrocarbons form bonds with other atoms in order to create organic compounds.
Hydrocarbon derivatives are based on simple hydrocarbon compounds that contain only hydrogens and carbons. Hydrocarbon derivatives contain at least one element other than hydrogen or carbon, such as oxygen, nitrogen or one of the halogen atoms (elements in column 7A of the Periodic Table.
Organic reactions are chemical reactions involving organic compounds. Organic reactions are used in the construction of new organic molecules. The production of many man-made chemicals such as drugs, plastics, food additives, fabrics depend on organic reactions.
Organic chemistry involves the study of the structure, properties, composition, reactions, and preparation of carbon-containing compounds, which include not only hydrocarbons but also compounds with any number of other elements, including hydrogen (most compounds contain at least one carbon–hydrogen bond), nitrogen, oxygen, halogens, phosphorus, silicon, and sulfur.
This branch of chemistry was originally limited to compounds produced by living organisms but has been broadened to include human-made substances such as plastics. The range of application of organic compounds is enormous and also includes, but is not limited to, pharmaceuticals, petrochemicals, food, explosives, paints, and cosmetics.
Organic chemistry is the study of the structure, properties, composition, reactions, and preparation of carbon-containing compounds, which include not only hydrocarbons but also compounds with any number of other elements, including hydrogen (most compounds contain at least one carbon–hydrogen bond), nitrogen, oxygen,
Science and technology studies, or science, technology and society studies (STS) is the study of how society, politics, and culture affect scientific research and technological innovation, and how these, in turn, affect society, politics and culture.
Isomers are molecules with the same molecular formula, but different structural or spatial arrangements of the atoms within the molecule. The reason there are such a colossal number of organic compounds which is more than 10 million is partly due to isomerism.
Apportionment is Apportionment involves dividing something up, just like fair division.
Voting is a method for a group, such as, a meeting or an electorate to make a collective decision or express an opinion, usually following discussions, debates or election campaigns.
Lipid metabolism entails the oxidation of fatty acids to either generate energy or synthesize new lipids from smaller constituent molecules. Lipid metabolism is associated with carbohydrate metabolism, as products of glucose (such as acetyl CoA) can be converted into lipids.
A Hamiltonian path is a path that visits each vertex of the graph exactly once.
A Hamiltonian circuit is a path that uses each vertex of a graph exactly once and returns to the starting vertex.
Carbohydrate metabolism involves the different biochemical processes responsible for the formation, breakdown, and interconversion of carbohydrates in living organisms.
A graph is a diagram displaying data which show the relationship between two or more quantities, measurements or indicative numbers that may or may not have a specific mathematical formula relating them to each other.
Every organism is composed of several different types of human body tissue. The human body tissue is another way of describing how our cells are grouped together in a highly organized manner according to specific structure and function. These groupings of cells form tissues, which then make up organs and various parts of the body.
Reproduction means producing offspring that may or may not be exact copies of their parents. It is a part of a life cycle, which is a series of events wherein individuals grow, develop, and reproduce according to a program of instructions encoded in DNA, which they inherit from their parents. When cells divide, each daughter cell receives a complete copy of DNA and enough cytoplasmic machinery to start up its own operation. DNA contains the blueprints for making different proteins.
.Enzymes are proteins that catalyze or speed up chemical reactions. They also help digest the foods we eat food and heal our wounds. They play major roles in respiration, making proteins, and DNA replication..
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...Ana Luísa Pinho
Functional Magnetic Resonance Imaging (fMRI) provides means to characterize brain activations in response to behavior. However, cognitive neuroscience has been limited to group-level effects referring to the performance of specific tasks. To obtain the functional profile of elementary cognitive mechanisms, the combination of brain responses to many tasks is required. Yet, to date, both structural atlases and parcellation-based activations do not fully account for cognitive function and still present several limitations. Further, they do not adapt overall to individual characteristics. In this talk, I will give an account of deep-behavioral phenotyping strategies, namely data-driven methods in large task-fMRI datasets, to optimize functional brain-data collection and improve inference of effects-of-interest related to mental processes. Key to this approach is the employment of fast multi-functional paradigms rich on features that can be well parametrized and, consequently, facilitate the creation of psycho-physiological constructs to be modelled with imaging data. Particular emphasis will be given to music stimuli when studying high-order cognitive mechanisms, due to their ecological nature and quality to enable complex behavior compounded by discrete entities. I will also discuss how deep-behavioral phenotyping and individualized models applied to neuroimaging data can better account for the subject-specific organization of domain-general cognitive systems in the human brain. Finally, the accumulation of functional brain signatures brings the possibility to clarify relationships among tasks and create a univocal link between brain systems and mental functions through: (1) the development of ontologies proposing an organization of cognitive processes; and (2) brain-network taxonomies describing functional specialization. To this end, tools to improve commensurability in cognitive science are necessary, such as public repositories, ontology-based platforms and automated meta-analysis tools. I will thus discuss some brain-atlasing resources currently under development, and their applicability in cognitive as well as clinical neuroscience.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
What is greenhouse gasses and how many gasses are there to affect the Earth.moosaasad1975
What are greenhouse gasses how they affect the earth and its environment what is the future of the environment and earth how the weather and the climate effects.
This presentation explores a brief idea about the structural and functional attributes of nucleotides, the structure and function of genetic materials along with the impact of UV rays and pH upon them.
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...University of Maribor
Slides from:
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Track: Artificial Intelligence
https://www.etran.rs/2024/en/home-english/
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
3. STOICHIOMETRY - DEALS WITH THE NUMERICAL
RELATIONSHIPS OF ELEMENTS AND COMPOUNDS AND
THE MATHEMATICAL PROPORTIONS OF REACTANTS
AND PRODUCTSIN CHEMICAL TRANSFORMATIONS
4. AN UNDERSTANDING OF THE MOLE CONCEPT
TOGETHER WITH SOME SKILLS IN WRITING AND
BALANCING CHEMICAL EQUATIONS ENABLE US TO
SOLVE STOICHIOMETRIC PROBLEMS INVOLVING
MASS RELATIONS OF REACTANTS AND PRODUCTS IN
CHEMICAL REACTIONS.
5. In chemical calculations it is necessary to consider
quantities of substances in terms of the number of
atoms, ions or molecules present. The unit devised by
chemists in expressing numbers of atoms, ions, or
moleculesiscalled themole.
A moleisdefined as that quantity of asubstancethat
contains the same number of ultimate particles (atom,
ions, or units of ions) as are present in 12g of Carbon
-12.
MOLE
6. 1 MOLE OF ANY ELEMENT ISAN AMOUNT
EQUAL TO ITSATOMIC MASSIN GRAMS, ITS
MOLAR MASS.
7. MOLECULAR MASS
Molecular mass equals the sum of the atomic masses of all atoms
in themolecule.
Theunit of molecular massistheamu.
Example:
What isthemolecular weight of sugar cane: C12 H22 O11 ?
12 C atoms = 12(12.011) amu = 144.132 amu
22 H atoms = 22(1.0079) amu = 22.174 amu
11 O atoms = 11(15.9994) amu = 175.993 amu
394.299 amu
8.
9. MOLAR MASS
Themolar massisthesum of themassesof theatoms
present in onemoleof asubstance, which can bean
element or acompound. It can beexpressed asaunit of
massper molelikegrams/mol, kg/mol.
Molar Massisan amount of thecompound equal to its
molecular massin grams. Theunit of molar massisthe
gram.
10.
11.
12. EXAMPLES:
1. Find themolar massof:
a. Al = 27 g/mol
b. Ca(OH)2 = 74 g/mol
Ca= 1 at x 40 g/mol = 40 g
O = 2 at x 16 g/mol = 32 g
H = 2 at x 1 g/mol = 2 g
74 g/mol
13. 2. How many molesarepresent in:
a. 5.4 g of Al
5.4 g x 1 mol = 0.2 mol
27 g
b. 180 g of H2O
180 g x 1 mol = 10 mol
18 g
3. What isthemassof 5 mol of Ca(OH)2
5 mol x 74 g = 370 g
mol
2 mol x 27 g = 26 g
mol
14. EXERCISES:
1. Calculate the formula mass of ammonium
sulfate(NH4)2 SO4.
2. Find themolar massof Ca3(PO4)2.
3. Calculate the number of moles of Oxygen (O2 )
in 24.0 g of O2.
4. Calculate the molecular mass of C7 H5 NO3 S
(Saccharin).
15. AVOGADRO’SNUMBER
The number of molecules in a mole of any molecular substance the same as the
number of atoms in a gram-atom of any number. This number of atom is
called theAvogadro’snumber, theaccepted valueof which is6.02483 x 1023
atoms/gram-atom of any element.
A mole is the amount of substance that contains as Avogadro’s number of
particlesequal to 6.02 x 1023
. Theparticlescan beatoms, molecules, or ions.
Examples:
Thereare6.02 x 1023
atomsin 1 moleof carbon
Thereare6.02 x 1023
moleculesin 1 moleof H2O
Thereare6.02 x 1023
Na
6.02 x 10 Cl in 1 moleof NaCl
16.
17.
18. EXAMPLES:
4. How many atomsarepresent in:
a. 5 mol of copper
5 mol x 6.02 x 1023
atoms = 30.10 or 3.01x 1023
atoms
mol
b. 48 g of carbon
48 g x 1 mol x 6.02 x 1023
atoms = 24.08 x 1023
or
12 g mol 24.08 x 1023
atoms
5. How many g of H2O will contain 3.01 x 1024
molecules?
3.01 x 1024
moleculesx 1 mol x 18 g = 90g
6.02 x 1023
molecules mol
21. PERCENTAGE COMPOSITION
the percentage of each element present in a compound.
In chemistry, this composition is always on a weight
basis unless specifically stated otherwise. Sometimes
the composition of the mixture of gases is given on a
volumetric basis.
based upon the meaning of the symbols and formulas.
Each symbol stands for one atomic weight’s worth of
the element it represents, and each formula stands for
one molecular weight’s worth of the compound it
represents.
22. EXAMPLES:
1. What isthepercentagecomposition of water?
% H = 2g x 100% = 11.11%
18g
% O = 18g x 100% = 88.89%
18g 100%
2. What isthepercentagecomposition of H2SO4?
% H = 2 g x 100% = 2.0%
98.1
% S = 32.1g x 100% = 32.7%
98.1g
% O = 64.0 g x 100% = 65.3%
98.1g 100%