This document compares the layout design of a CMOS AND gate using two approaches: fully automatic and semicustom. In the fully automatic approach, the AND gate schematic is developed in DSCH and compiled in MICROWIND to automatically generate the layout. This layout consumes 43.7 μm2 of area and 3.1 μW of power. In the semicustom approach, the layout is manually designed in MICROWIND for area optimization. This layout consumes only 11.2 μm2 of area while consuming similar power as the automatic design. Simulation results show that the semicustom layout reduces area consumption significantly compared to the fully automatic layout, though it may consume slightly more power.