Pulmonary stenosis (also called pulmonic stenosis) is when the pulmonary valve (the valve between the right ventricle and the pulmonary artery) is too small, narrow, or stiff. Symptoms of pulmonary stenosis depend on how small the narrowing of the pulmonary valve is
This power point is prepared from text books, guidelines and literature. so it will be up date based on the need and not used for management of patients.
Heart failure, sometimes known as congestive heart failure, occurs when your heart muscle doesn't pump blood as well as it should. Certain conditions, such as narrowed arteries in your heart (coronary artery disease) or high blood pressure, gradually leave your heart too weak or stiff to fill and pump efficiently.
Pulmonary stenosis (also called pulmonic stenosis) is when the pulmonary valve (the valve between the right ventricle and the pulmonary artery) is too small, narrow, or stiff. Symptoms of pulmonary stenosis depend on how small the narrowing of the pulmonary valve is
This power point is prepared from text books, guidelines and literature. so it will be up date based on the need and not used for management of patients.
Heart failure, sometimes known as congestive heart failure, occurs when your heart muscle doesn't pump blood as well as it should. Certain conditions, such as narrowed arteries in your heart (coronary artery disease) or high blood pressure, gradually leave your heart too weak or stiff to fill and pump efficiently.
A presentation created and delivered by me in the pediatric department of Ibrahim Malik Teaching Hospital (Khartoum, Sudan) on the 10th of May 2017. It is composed of the following parts:
- Definition
- Epidemiology
- Causes
- Assessment
- Management
The total number of slides is 19 slide. One of the slides contain a video from the IMCI program by World Health Organization (WHO) for assessment of children with dehydration. The youtube link of the video added in this online version instead of the complete video that was shown in the original presentation.
PREVIEW OF EMT/EMR PEDIATRIC EMERGENCIES POWERPOINT TRAINING PRESENTATIONBruce Vincent
Presents information concerning the developmental and anatomical differences in infants and children, discuss common medical and trauma situations, and also covered are infants children dependent on special technology. Dealing with an ill or injured infant or child patient has always been a challenge for EMS providers. Presentation is over 100 slides in length. Meets or exceeds USDOT NHTSA 2009 Training Standards.
presentation regarding investigations and treatment of heart failure in pediatrics, including the management of an emergency , and includes brief description about even drugs used
Mechanical Ventilation Cheat Book for Internal Medicine ResidentsThe Medical Post
This short cheat book talks about basic concepts and physiology of artificial ventilation and also elaborates on point guided approach in maneuvering different modes of mechanical ventilation. Consider this as a basic overview and is intended for all internal medicine residents.
Salient features of the book are -
- The book provides a shortcut to understand and remember certain specific formulae and points you require to interpret the 12-lead ECG.
- Treatment protocols (in green boxes) for most of the important conditions are also included.
- View sample ECGs as you read along the topics.
- The content is explained in a very simple language to provide good conceptions, written from a student’s point of view.
- People can gain their belief in the book after going through sample ECGs which would be available at www.themedicalpost.net/ecg
- The book competes with the other books available in the market in simplicity, summaries, treatment protocols, live diagrams and regularly updated sample ECGs on the website.
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists
Congestive Cardiac Failure
1. Congestive Cardiac Failure
Dr. Kalpana Malla
MBBS MD (Pediatrics)
Manipal Teaching Hospital
Download more documents and slide shows on The Medical Post [ www.themedicalpost.net ]
2. CCF
• CCF – inability of the heart to maintain an
output at rest or during distress, necessary for
the metabolic needs of the body (systolic
failure) and inability to receive blood into the
ventricular cavities at low pressure during
diastole (diastolic failure)
5. Clinical features
• Symptoms
1.Poor wt gain FTT- small feeds due to easy
fatigability
Excess loss of calories due to increased work of
breathing with CCF
2. Unusual wt gain due to edema
3. Shortness of breath
4.Fatigue from feeding – poor sucking
6. Clinical features
• Irritable,persistent crying –hunger, orthopnia
• Sweating
• Wheezing
Cardinal features of CCF in children
1.Tachycardia
2. Tachypnea
3.Hepatomegaly
4.Cardiomegaly
8. Investigations
• X-ray chest –cardiomegaly ,fluffy peripheral
pulmonary markings due to venous
congestion and pulmonary edema
• ECG helps to find the cause-hypertrophy
,arrhythmia
• Echo- for cause
• Blood count
• ABG
9. Management
• Reduce cardiac work
• Augment myocardial contractility
• Improve cardiac performance by reducing
heart size
• Correct the underlying cause
10. Reduce cardiac work
1. Restrict activities, position – propped up – pooling
of edema in dependant areas which reduces the
fluids in lungs – reduce work
2. Oxygen – improves impaired oxygenation
secondary to lung congesion so reduce work
3. Sedatives- decreases restlessness & dyspnea.
morphine .05mg/kg s/c or diazepam
4.Treat fever – circulatory & metabolic needs minimal
at normal temp thus reduce work,
11. Reduce cardiac work
5. Treat – anemia-decreased oxygen carrying capacity
imposes stress to heart
6.Treat infection
• Vasodilators –
• Reduce arteriolar and venous vasoconstriction –
reduce work of heart
• A. constriction - ↑systemic vascular resistance
• Venoconstriction - ↑ venous return- ↑filling
pressure- ↑CO
12. Vasodilators
1.ACE inhibitors – suppress renin angiotensin A
system –
- vasodilators +
- prevent Na+ & water retention
- prevent K+ loss
2.Others combinations: hydralazine (arteriole) +
isosorbide nitrate ( Vein)
3.Sodium nitroprusside (Atery + vein)
13. 2.Augment myocardial contractility
• Digitalis – ionotropic drug
• 1st dose – ½ of TDD
• 2nd dose – ¼ of TDD after 8 hrs of 1st dose
• 3rd dose – ¼ of TDD after 16 hrs of 2nd dose
• Maintenance dose – ¼ 0f TDD 12hrly 12hrs
after the 3rd dose
14. Initial Oral Digitalization dose
(IV or IM dose is 2/3 of oral dose
• Loading Maintenance
• Premature newborn
<1500 gms- 0.02 mg/kg 0.005 mg/kg
>1500 gms- 0.04 mg/kg 0.01 /kg
• Term NB - 6mo- 0.04 mg/kg 0.01 mg/kg
• 6 mo – 2 yrs - 0.06 mg/kg 0.015 mg/kg
• 2 yrs – 10yrs - 0.04 mg/kg 0.01 mg/kg
• >10 years0.04 mg/kg 0.01 mg/kg
15. Types of digitalization
1.Rapid digitalization – given IV within 24 hrs in
acute CCF, critically ill .Maintenance dose
given orally
2.Routine schedule – given orally within 24 hrs,
not critically ill
3.Slow digitalization – out patient basis ,with
chronic CCF. full digitalization is achieved in 7-
10 days-1/4th of TDD 12hrly without prior
loading dose
16. 3. Improve cardiac performance by
reducing heart size
• Digitalis
• Diuretics – reduce blood volume, venous
return and ventricular filling- reduce heart size
• Salt restriction – reduce volume
• 4. correct the underlying cause