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MENSTRUAL CYCLE
MENSTRUAL CYCLE
• The cyclic events that take place in a rhythmic
manner during the reproductive period of woman’s
life
• It starts at the age of ‘12-15’ years and ceases at the
age of ‘45-50’ years
• First menstrual cycle “menarche”
• The permanent cessation of menstrual cycle in old
age – “menopause”
• Menstrual cycle constitute both “uterine cycle” and
“ovarian cycle”
• Normal duration is “28 days”
• It may vary b/w 25 and 35 days under physiological
conditions
• OVARIAN CYCLE OR
EVENTS
• Follicular changes and
hormone secretions
1. Follicular phase
2. Ovulation
3. Luteal phase
• UTERINE CYCLE OR
EVENTS
• Uterine changes and
preparation for
fertilization and ovum
implantation
1. Proliferative phase
2. Secretory phase
3. Menstrual phase
OVARIAN CYCLE
1. Follicular phase
2. Ovulation
3. Luteal phase
OVARIAN CYCLE
• Day 0 – 14 : Follicular phase (preovulatory stage)
• Maturation of follicle into secondary follicle
• FSH and LH
• Stimulates “oocyte” development and “follicle
growth” primordial follicle, to primary follicle, into
secondary follicle
• Estrogen
• Reaches its peak
OVARIAN CYCLE
• Day 14 – 15 : Ovulation (Release of matured
ovum)
• Graafian follicle (containing ovum)
• FSH and LH rapidly
• LH burst occurs – ovulation starts
• Day 15 – 28 : Luteal phase (Postovulatory stage)
• Formation of “corpus luteum” (yellow body)
• FSH and LH decline
• Estrogen moderates level
• Progesterone
• Reaches its peak
• Corpus hemorrhagicum - corpus luteum - corpus
albicans (white body)
UTERINE CYCLE
1. Menstrual phase or pregnancy
2. Proliferative phase (preovulatory)
3. Secretory phase (postovulatory)
• Day 0 – 7 : Menstrual phase or pregnancy
• Sudden reduction in estrogen and progesterone
• (50 – 150 ml blood loss with shedding of stratum
functionalis layer of uterine endometrium)
• 2 – 5 mm thickness
• Day 7 – 14 : Proliferative phase (preovulatory)
• Starts at the end of “menstrual phase”
• Uterine lining thickens (4 – 10 mm)
• “Stratum basalis” undergoes mitosis
• Produces “stratum functionalis”
• Estrogen
• Day 14 – 28 : Secretory phase (postovulatory)
• Starts with “ovulation”
• Uterine lining extremely thickened (12 – 18 mm)
• Progesterone and estrogen secretion rises
• Inhibits LH and FSH release
• Day 0 : Menstrual phase or pregnancy
• If fertilization occurs, lining is maintained
• If not, lining is shed and will recycle next month
HORMONAL CHANGES DURING MENSTRUAL CYCLE
UTERINE CHANGES DURING MENSTRUAL CYCLE

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MENSTRUAL CYCLE.pptx

  • 2. MENSTRUAL CYCLE • The cyclic events that take place in a rhythmic manner during the reproductive period of woman’s life
  • 3. • It starts at the age of ‘12-15’ years and ceases at the age of ‘45-50’ years • First menstrual cycle “menarche” • The permanent cessation of menstrual cycle in old age – “menopause”
  • 4. • Menstrual cycle constitute both “uterine cycle” and “ovarian cycle” • Normal duration is “28 days” • It may vary b/w 25 and 35 days under physiological conditions
  • 5. • OVARIAN CYCLE OR EVENTS • Follicular changes and hormone secretions 1. Follicular phase 2. Ovulation 3. Luteal phase • UTERINE CYCLE OR EVENTS • Uterine changes and preparation for fertilization and ovum implantation 1. Proliferative phase 2. Secretory phase 3. Menstrual phase
  • 6. OVARIAN CYCLE 1. Follicular phase 2. Ovulation 3. Luteal phase
  • 7. OVARIAN CYCLE • Day 0 – 14 : Follicular phase (preovulatory stage) • Maturation of follicle into secondary follicle • FSH and LH • Stimulates “oocyte” development and “follicle growth” primordial follicle, to primary follicle, into secondary follicle • Estrogen • Reaches its peak
  • 8. OVARIAN CYCLE • Day 14 – 15 : Ovulation (Release of matured ovum) • Graafian follicle (containing ovum) • FSH and LH rapidly • LH burst occurs – ovulation starts
  • 9. • Day 15 – 28 : Luteal phase (Postovulatory stage) • Formation of “corpus luteum” (yellow body) • FSH and LH decline • Estrogen moderates level • Progesterone • Reaches its peak • Corpus hemorrhagicum - corpus luteum - corpus albicans (white body)
  • 10. UTERINE CYCLE 1. Menstrual phase or pregnancy 2. Proliferative phase (preovulatory) 3. Secretory phase (postovulatory)
  • 11. • Day 0 – 7 : Menstrual phase or pregnancy • Sudden reduction in estrogen and progesterone • (50 – 150 ml blood loss with shedding of stratum functionalis layer of uterine endometrium) • 2 – 5 mm thickness
  • 12. • Day 7 – 14 : Proliferative phase (preovulatory) • Starts at the end of “menstrual phase” • Uterine lining thickens (4 – 10 mm) • “Stratum basalis” undergoes mitosis • Produces “stratum functionalis” • Estrogen
  • 13. • Day 14 – 28 : Secretory phase (postovulatory) • Starts with “ovulation” • Uterine lining extremely thickened (12 – 18 mm) • Progesterone and estrogen secretion rises • Inhibits LH and FSH release
  • 14. • Day 0 : Menstrual phase or pregnancy • If fertilization occurs, lining is maintained • If not, lining is shed and will recycle next month
  • 15. HORMONAL CHANGES DURING MENSTRUAL CYCLE
  • 16. UTERINE CHANGES DURING MENSTRUAL CYCLE