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OOGENESIS
• Process of formation of female gamete “ovum”
• Starts in fetal life, ends at “menopause”
PRIMORDIAL GERM CELLS (OOGONIA) (Migrate from yolk sac 6th week of gestation)
OOGENESIS
MITOTIC DIVISION
OOGONIA (7 Millions)
PRIMARY OOCYTES (46) MEIOTIC DIVISION
I (fetal life, 8th
week)
(Meiotic arrest in
prophase )
SECONDARY OOCYTES (23)
MEIOTIC DIVISION
II (at fertilization)
(Meiotic arrest in
prophase )
OVUM
SECOND POLAR BODY
FIRST POLAR BODY
FOLLICULOGENESIS
• Growth and development of “matured follicle -
containing ovum” from “primordial follicle”
• “Four” stages
• Stage I : Primordial follicular stage
• Stage II : Primary follicular stage
• Stage III : Secondary follicular stage
• Stage IV : Tertiary follicular stage
FOLLICULOGENESIS
Stage I : Primordial follicular stage
• Consists “primary oocyte (25µm)”
• Flattened “pregranulosa cells”
• Enters to “meiosis I”
• Arrested in “prophase”
Stage II : Primary follicular stage
• Formed from “primordial follicle”
• “Cuboidal granulosa cells”
• “Oocyte” (80-140 µm)
• Forms “zona pellucida” layer
Stage III : Secondary follicular stage
• Primary follicles to “secondary follicles”
• 500 µm
• Development of “antrum” – “preantral follicle”
Stage IV : Tertiary follicular stage
• Final stage
• Two sub divisions
1. Early tertiary or antral follicular stage
2. Late tertiary or Graafian follicular stage
• “20 mm”
GRAAFIAN FOLLICLE

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OOGENESIS FOLLICULOGENESIS GRAAFIAN FOLLICLE.pptx

  • 2. • Process of formation of female gamete “ovum” • Starts in fetal life, ends at “menopause”
  • 3.
  • 4. PRIMORDIAL GERM CELLS (OOGONIA) (Migrate from yolk sac 6th week of gestation) OOGENESIS MITOTIC DIVISION OOGONIA (7 Millions) PRIMARY OOCYTES (46) MEIOTIC DIVISION I (fetal life, 8th week) (Meiotic arrest in prophase ) SECONDARY OOCYTES (23) MEIOTIC DIVISION II (at fertilization) (Meiotic arrest in prophase ) OVUM SECOND POLAR BODY FIRST POLAR BODY
  • 6. • Growth and development of “matured follicle - containing ovum” from “primordial follicle”
  • 7. • “Four” stages • Stage I : Primordial follicular stage • Stage II : Primary follicular stage • Stage III : Secondary follicular stage • Stage IV : Tertiary follicular stage
  • 9. Stage I : Primordial follicular stage • Consists “primary oocyte (25µm)” • Flattened “pregranulosa cells” • Enters to “meiosis I” • Arrested in “prophase”
  • 10. Stage II : Primary follicular stage • Formed from “primordial follicle” • “Cuboidal granulosa cells” • “Oocyte” (80-140 µm) • Forms “zona pellucida” layer
  • 11. Stage III : Secondary follicular stage • Primary follicles to “secondary follicles” • 500 µm • Development of “antrum” – “preantral follicle”
  • 12. Stage IV : Tertiary follicular stage • Final stage • Two sub divisions 1. Early tertiary or antral follicular stage 2. Late tertiary or Graafian follicular stage • “20 mm”