The document summarizes the oxygen-hemoglobin dissociation curve, which plots the percentage of hemoglobin in its oxygen-saturated form against the partial pressure of oxygen. It describes how hemoglobin, composed of heme and globin units, can bind reversibly to oxygen molecules. The curve has a plateau portion where little oxygen is released from hemoglobin at high oxygen pressures in the lungs, and a steep portion where hemoglobin readily unloads oxygen at lower pressures in tissues. An important measurement of hemoglobin's oxygen affinity is P50, the partial pressure at which hemoglobin is 50% saturated with oxygen, which can shift based on conditions.