THROMBOCYTOPENIA is decreased platelet count we call it thrombocytopenias. causes of this are called an infection, cancer condition, some type of the drugs like heparin, etc. signs and symptoms of the is bleeding tendency patiche, purpuraetc/ the management of this is plasma transfusion admin situation of some of the drug immunotherapy is helpful for this condition. surgery splenectomy.
Aplastic anemia is one of the stem cell disorder which leads to pancytopenia in the peripheral blood and decrease production of all cell line in bone marrow. it require bone marrow transplantation to cure the patient.
THROMBOCYTOPENIA is decreased platelet count we call it thrombocytopenias. causes of this are called an infection, cancer condition, some type of the drugs like heparin, etc. signs and symptoms of the is bleeding tendency patiche, purpuraetc/ the management of this is plasma transfusion admin situation of some of the drug immunotherapy is helpful for this condition. surgery splenectomy.
Aplastic anemia is one of the stem cell disorder which leads to pancytopenia in the peripheral blood and decrease production of all cell line in bone marrow. it require bone marrow transplantation to cure the patient.
Thalassemia is a blood disorder passed down through families (inherited) in which the body makes an abnormal form or inadequate amount of hemoglobin. Hemoglobin is the protein in red blood cells that carries oxygen. The disorder results in large numbers of red blood cells being destroyed, which leads to anemia.
This PPT covers pathophysiology of thrombocytopenia which includes causes of thrombocytopenia, symptoms of thrombocytopenia and diagnosis of thrombocytopenia
Megaloblastic anaemia is a red blood cell disorder due to the inhibition of DNA synthesis during erythropioesis.
Mitotically, the inhibition of the DNA synthesis impaires the progression of the cell cycle development from G2 to (M) stage.
Image result for thalassemia
Image result for thalassemia
Image result for thalassemia
Image result for thalassemia
Image result for thalassemia
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View all Thalassemia (thal-uh-SEE-me-uh) is an inherited blood disorder that causes your body to have less hemoglobin than normal.
Anemia Causes, Types, Symptoms, Diet, and Treatment Dr Medical
https://userupload.net/0gv9ijneu7hf
Anemia is a condition that develops when your blood lacks enough healthy red blood cells or hemoglobin. Hemoglobin is a main part of red blood cells and binds oxygen. If you have too few or abnormal red blood cells, or your hemoglobin is abnormal or low, the cells in your body will not get enough oxygen.
Approach to Pancytopenia with cases.pptxYogeetaTanty1
Approach to pancytopenia with case based discussion and brief details regarding each condition. Causes of pancytopenia. Details of congenital causes of aplastic anemia.
Thalassemia is a blood disorder passed down through families (inherited) in which the body makes an abnormal form or inadequate amount of hemoglobin. Hemoglobin is the protein in red blood cells that carries oxygen. The disorder results in large numbers of red blood cells being destroyed, which leads to anemia.
This PPT covers pathophysiology of thrombocytopenia which includes causes of thrombocytopenia, symptoms of thrombocytopenia and diagnosis of thrombocytopenia
Megaloblastic anaemia is a red blood cell disorder due to the inhibition of DNA synthesis during erythropioesis.
Mitotically, the inhibition of the DNA synthesis impaires the progression of the cell cycle development from G2 to (M) stage.
Image result for thalassemia
Image result for thalassemia
Image result for thalassemia
Image result for thalassemia
Image result for thalassemia
Image result for thalassemia
View all Thalassemia (thal-uh-SEE-me-uh) is an inherited blood disorder that causes your body to have less hemoglobin than normal.
Anemia Causes, Types, Symptoms, Diet, and Treatment Dr Medical
https://userupload.net/0gv9ijneu7hf
Anemia is a condition that develops when your blood lacks enough healthy red blood cells or hemoglobin. Hemoglobin is a main part of red blood cells and binds oxygen. If you have too few or abnormal red blood cells, or your hemoglobin is abnormal or low, the cells in your body will not get enough oxygen.
Approach to Pancytopenia with cases.pptxYogeetaTanty1
Approach to pancytopenia with case based discussion and brief details regarding each condition. Causes of pancytopenia. Details of congenital causes of aplastic anemia.
Group Dynamic(presentation for nursing management)ABHIJIT BHOYAR
Group dynamics is a system of behaviors and psychological processes occurring within a social group (intragroup dynamics), or between social groups (intergroup dynamics)
the practice of training people to obey rules and behave well.
the practice of training your mind and body so that you control your actions and obey rules; a way of doing this
Isoenzymes (or isozymes) are a group of enzymes that catalyze the same reaction but have different enzyme forms and catalytic efficiencies. Isozymes are usually distinguished by their electrophoretic mobilities.
An enzyme is a biological catalyst and is almost always a protein. It speeds up the rate of a specific chemical reaction in the cell. The enzyme is not destroyed during the reaction and is used over and over.
A complete cholesterol test — also called a lipid panel or lipid profile — is a blood test that can measure the amount of cholesterol and triglycerides in your blood
Cholesterol is a waxy substance found in your blood. Your body needs cholesterol to build healthy cells, but high levels of cholesterol can increase your risk of heart disease.
Lipid metabolism entails the oxidation of fatty acids to either generate energy or synthesize new lipids from smaller constituent molecules. Lipid metabolism is associated with carbohydrate metabolism,
LIPIDS-Digestion and absorption of Lipids.pptxABHIJIT BHOYAR
The digestion of lipids begins in the oral cavity through exposure to lingual lipases, which are secreted by glands in the tongue to begin the process of digesting triglycerides.
The term essential fatty acids (EFA) refers to those polyunsaturated fatty acids (PUFA) that must be provided by foods because these cannot be synthesized in the body yet are necessary for health
Fatty acids are the building blocks of the fat in our bodies and in the food we eat. During digestion, the body breaks down fats into fatty acids, which can then be absorbed into the blood. Fatty acid molecules are usually joined together in groups of three, forming a molecule called a triglyceride.
Once the egg has left the ovary it can be fertilized and implant itself in the lining of the uterus. The main function of the uterus is to nourish the developing fetus prior to birth.
he kidneys are a vital organ critical to the human body. From filtering waste from blood to produce red blood cells, it serves a crucial role. With cells and tissue that work together in synchronized form for common function
If you like share this PPT presentation to nursing students. The pancreas is an organ and a gland. Glands are organs that produce and release substances in the body. The pancreas performs two main functions: Exocrine function: Produces substances (enzymes) that help with digestion.
he spleen is a fist-sized organ found in the upper left side of your abdomen, next to your stomach and behind your left ribs. It's an important part of your immune system but you can survive without it. This is because the liver can take over many of the spleen's functions
The Popliteal Fossa is a diamond-shaped space behind the knee joint. It is formed between the muscles in the posterior compartments of the thigh and leg. This anatomical landmark is the major route by which structures pass between the thigh and leg.
Welcome to Secret Tantric, London’s finest VIP Massage agency. Since we first opened our doors, we have provided the ultimate erotic massage experience to innumerable clients, each one searching for the very best sensual massage in London. We come by this reputation honestly with a dynamic team of the city’s most beautiful masseuses.
Telehealth Psychology Building Trust with Clients.pptxThe Harvest Clinic
Telehealth psychology is a digital approach that offers psychological services and mental health care to clients remotely, using technologies like video conferencing, phone calls, text messaging, and mobile apps for communication.
Leading the Way in Nephrology: Dr. David Greene's Work with Stem Cells for Ki...Dr. David Greene Arizona
As we watch Dr. Greene's continued efforts and research in Arizona, it's clear that stem cell therapy holds a promising key to unlocking new doors in the treatment of kidney disease. With each study and trial, we step closer to a world where kidney disease is no longer a life sentence but a treatable condition, thanks to pioneers like Dr. David Greene.
Navigating the Health Insurance Market_ Understanding Trends and Options.pdfEnterprise Wired
From navigating policy options to staying informed about industry trends, this comprehensive guide explores everything you need to know about the health insurance market.
We understand the unique challenges pickleball players face and are committed to helping you stay healthy and active. In this presentation, we’ll explore the three most common pickleball injuries and provide strategies for prevention and treatment.
One of the most developed cities of India, the city of Chennai is the capital of Tamilnadu and many people from different parts of India come here to earn their bread and butter. Being a metropolitan, the city is filled with towering building and beaches but the sad part as with almost every Indian city
Antibiotic Stewardship by Anushri Srivastava.pptxAnushriSrivastav
Stewardship is the act of taking good care of something.
Antimicrobial stewardship is a coordinated program that promotes the appropriate use of antimicrobials (including antibiotics), improves patient outcomes, reduces microbial resistance, and decreases the spread of infections caused by multidrug-resistant organisms.
WHO launched the Global Antimicrobial Resistance and Use Surveillance System (GLASS) in 2015 to fill knowledge gaps and inform strategies at all levels.
ACCORDING TO apic.org,
Antimicrobial stewardship is a coordinated program that promotes the appropriate use of antimicrobials (including antibiotics), improves patient outcomes, reduces microbial resistance, and decreases the spread of infections caused by multidrug-resistant organisms.
ACCORDING TO pewtrusts.org,
Antibiotic stewardship refers to efforts in doctors’ offices, hospitals, long term care facilities, and other health care settings to ensure that antibiotics are used only when necessary and appropriate
According to WHO,
Antimicrobial stewardship is a systematic approach to educate and support health care professionals to follow evidence-based guidelines for prescribing and administering antimicrobials
In 1996, John McGowan and Dale Gerding first applied the term antimicrobial stewardship, where they suggested a causal association between antimicrobial agent use and resistance. They also focused on the urgency of large-scale controlled trials of antimicrobial-use regulation employing sophisticated epidemiologic methods, molecular typing, and precise resistance mechanism analysis.
Antimicrobial Stewardship(AMS) refers to the optimal selection, dosing, and duration of antimicrobial treatment resulting in the best clinical outcome with minimal side effects to the patients and minimal impact on subsequent resistance.
According to the 2019 report, in the US, more than 2.8 million antibiotic-resistant infections occur each year, and more than 35000 people die. In addition to this, it also mentioned that 223,900 cases of Clostridoides difficile occurred in 2017, of which 12800 people died. The report did not include viruses or parasites
VISION
Being proactive
Supporting optimal animal and human health
Exploring ways to reduce overall use of antimicrobials
Using the drugs that prevent and treat disease by killing microscopic organisms in a responsible way
GOAL
to prevent the generation and spread of antimicrobial resistance (AMR). Doing so will preserve the effectiveness of these drugs in animals and humans for years to come.
being to preserve human and animal health and the effectiveness of antimicrobial medications.
to implement a multidisciplinary approach in assembling a stewardship team to include an infectious disease physician, a clinical pharmacist with infectious diseases training, infection preventionist, and a close collaboration with the staff in the clinical microbiology laboratory
to prevent antimicrobial overuse, misuse and abuse.
to minimize the developme
1. SEMINAR
ON
TOPIC – APLASTIC ANEMIA IN
CHILDREN
SUBJECT - CHILD HEALTH NURSING
BY,
MR. ABHIJIT P. BHOYAR
M. SC. NURSING
CHILD HEALTH NURSING
2. APLASTIC ANAEMIA
• INTRODUCTION
• Aplastic anemia is a serious condition in which the
bone marrow does not produce enough new blood
cells.
• It may be passed down from the parents or develop
sometime during childhood.
Aplastic anaemia (AA) is a rare condition in which the bone marrow
fails to produce all three major types of blood cell. It is not a form of
cancer.
3. • Aplastic anemia is a type of anemia caused by
problems with bone marrow. It can range
from mild to severe.
4. CAUSES
• Unknown etiology
• Stem cell defect: intrinsic defects of
hematopoietic stem cells
• Bone marrow defects
• Abnormal hematopoiesis related
to humoral or cellular immune
function
• Adverse effects of certain drugs
5. CAUSES
• Exposure to certain chemicals and pathogens, such as contaminated
water, animal fertilizer, and pesticides
• Inherited conditions: mutations such as those present in the Shwachman-
Bodian-Diamond syndrome (SBDS) gene (occurs from biallelic mutations)
• Infections that cause autoimmune pathogenesis: immune mediated
hematopoietic cell destruction from conditions such as fulminant liver
failure (FLF), which occurs secondary to some forms of hepatitis,
echovirus, parvovirus, metabolic veno-occlusive disease and other
pathologies
6. RISK FACTORS
•Exposure to certain environmental toxins
•High dose radiation and chemotherapy
treatments
•Certain viruses
•Certain medications
•Bone marrow diseases
•Pregnancy
8. Types of aplastic anaemia
There are several types of aplastic anaemia:
• Acquired aplastic anaemia – this is the most common type
where there is often no obvious or known cause.
• Inherited bone marrow failure syndromes – there are rare
inherited conditions which may lead patients on to develop
aplastic anaemia. The most common of these is Fanconi
anaemia.
9. The classification is based on how low the numbers of blood cells have fallen, which can be
found out by a blood count.
• To make a diagnosis of AA, at least two of the following must be present:
• Haemoglobin less than 100g/L
• Platelet count less than 50 x 109/L
• Neutrophil count less than 1.5 x 109/L
• AA is classified as non-severe, severe or very severe.
• Non-severe aplastic anaemia
• This meets the above criteria for aplastic anaemia but does not meet the criteria for severe
or very severe aplastic anaemia.
• Severe aplastic anaemia
• Hypocellular bone marrow and any two of the following:
• A low platelet count (less than 20 x 109/L)
• A reticulocyte count less than 20 or 60 x 109/L
• A neutrophil count less than 0.5 x 109/L
• Very severe aplastic anaemia
• Hypocellular bone marrow and any two of the following:
• A low platelet count (less than 20 x 109/L)
• A reticulocyte count less than 20 or 60 x 109/L
• A neutrophil count less than 0.2 x 109/L
• The difference between severe and very severe AA is how low the number of neutrophils
falls; which increases the risk of severe infection.
• Hypocellular bone marrow is defined as bone marrow cells <25%, or 25-50% with less than
30% of stem cells in your bone marrow.
10. CLINICAL MANIFESTATIONS
• Fatigue
• Shortness of breath with activity
• Weakness
• Rapid heart rate
• Pale skin
• Easy bruising
• Nosebleeds and bleeding gums
• Lengthy bleeding from cuts
• Skin rash
• Fever
• Shortened attention span
16. NURSING MANAGEMENT
• Frequent assessment
• Monitoring for adverse effects
• Assessment of coping abilities
• Provide emotional support
• Patient and family teaching
17. COMPLICATION
Complications may include:
• Severe infections or bleeding
• Complications of bone marrow transplant
• Reactions to medicines
• Hemochromatosis (buildup of too much iron in the
body tissues from many red cell transfusions)
18. PREVENTION
• Limiting exposure to certain environmental toxins
• Environmental toxins include those found in
gasoline, paint, oil and coal emissions, and
industrial solvents.