1. Acute glomerulonephritis is a common kidney disease in children that is often preceded by a streptococcal infection. It causes blood in the urine and can lead to reduced urine output, swelling, and high blood pressure.
2. The disease is an immune-mediated inflammatory response in the glomeruli of the kidneys caused by antigen-antibody complexes depositing in the glomerular capillaries, resulting in kidney damage.
3. Treatment focuses on controlling symptoms like blood pressure and swelling through bed rest, fluid management, and medications. Antibiotics may be given if caused by a streptococcal infection.
Nephrotic syndrome is a kidney disorder that causes your body to pass too much protein in your urine. Nephrotic syndrome is usually caused by damage to the clusters of small blood vessels in your kidneys that filter waste and excess water from your blood.
Nephrotic syndrome is a kidney disorder that causes your body to pass too much protein in your urine. Nephrotic syndrome is usually caused by damage to the clusters of small blood vessels in your kidneys that filter waste and excess water from your blood.
Detailed Powerpoint Presentation on Wilms Tumour …. It includes definition with images, causes, sign and symptoms all treatment modalities with nursing responsibilities and recent research related to this...
This presentation was done by Dr. Julius P. Kessy,MD. An intern Doctor at Dodoma Regional Referral Hospital (DRRH) during pediatrics unit clinical meeting and supervised by Dr. Christina K. Galabawa,MD,Mmed2, Pediatrics and Child Health, University of Dodoma (UDOM) in November, 2017.
Pyelonephritis
It is the inflammation of the kidney & upper urinary tract that usually results from the bacterial infection of the bladder.
Pyelonephritis can be classified in several different catagories:
-acute pyelonephritis
-chronic pyelonephritis
-xanthogranulomatous pyelonephritis
kindly check this slide for nephrotic syndrome. in this slide i covered all the points regarding this topic.
if any suggestion give comment on this topic
Glomerulonephritis is inflammation of the tiny filters in your kidneys (glomeruli). Glomeruli remove excess fluid, electrolytes and waste from your bloodstream and pass them into your urine.
Detailed Powerpoint Presentation on Wilms Tumour …. It includes definition with images, causes, sign and symptoms all treatment modalities with nursing responsibilities and recent research related to this...
This presentation was done by Dr. Julius P. Kessy,MD. An intern Doctor at Dodoma Regional Referral Hospital (DRRH) during pediatrics unit clinical meeting and supervised by Dr. Christina K. Galabawa,MD,Mmed2, Pediatrics and Child Health, University of Dodoma (UDOM) in November, 2017.
Pyelonephritis
It is the inflammation of the kidney & upper urinary tract that usually results from the bacterial infection of the bladder.
Pyelonephritis can be classified in several different catagories:
-acute pyelonephritis
-chronic pyelonephritis
-xanthogranulomatous pyelonephritis
kindly check this slide for nephrotic syndrome. in this slide i covered all the points regarding this topic.
if any suggestion give comment on this topic
Glomerulonephritis is inflammation of the tiny filters in your kidneys (glomeruli). Glomeruli remove excess fluid, electrolytes and waste from your bloodstream and pass them into your urine.
acute glomerulonephritis in pediatrics by ritu gahlawatRitu Gahlawat
Case Scenario
A child 14 yrs. old, was apparently normal one week back, when he developed puffiness around the eye and face from last 7 days, insidious in onset, gradually progressive, from the peri-orbital region to the whole of face, more during morning hours and then decreases as the day progresses.
Then mother noticed swelling of bilateral lower limbs from 5 days, insidious in onset, gradually progressed from feet to half of the lower limb, more during morning hours and decreases as the day progresses.
Then he started to develop headache, insidious in onset, gradually progressive, more in the occipital region, not associated with vomiting, blurring vision, confusion, altered sensorium, seizures.
This was followed by cola coloured urine from four days, sudden onset, present throughout the urinary stream, not precipitated by any food item, no history of pain during micturition, fever, urgency, increased frequency of micturition, regular drug intake, associated with decreased urine output present from past one week initially used to pass 7-8 times/day and now only 3-4 times/day.
History of fever with sore throat present 3 weeks back, which resolved on its own in 3-4 days.
Introduction
Acute glomerulonephritis is a common disease in children and it is one of the diseases that are presented commonly with hematuria which means red urine (blood in urine).
Acute Glomerulo Nephritis in all probabilities results secondary to a proceeding streptococcal (beta-haemolytic type 2) infection of throat or skin.
A history of upper respiratory infection.
Acute glomerulonephritis is an immune-mediated inflammatory disease of the capillary loops in the renal glomeruli. The antigen-antibody complex deposition within the glomeruli results in glomerular injury which is manifested as hematuria, oliguria, Edema and hypertension.
More common in male than females.
Most common in preschool and early school age children with a peak age of onset of 6-7 years.
On average responsible for 2 to 4% of pediatric admission in India.
Accounts for about 90% of renal diseases in childhood.
Varies with the prevalence of nephritogenic strains of streptococci and the likelihood of cross-infection.
Presumed cause: antigen-antibody reaction secondary to an infection in the body.
Initial infection:
Usually either an upper respiratory infection or a skin infection, usually one to 3 weeks before the onset of symptoms.
Most frequent causative agent- nephritogenic strains of group- A beta- hemolytic streptococcus (type 2), acute post- streptococcal glomerulonephritis is the most common.
Most cases are post infectious and have been associated with pneumococcal, viral infection, acute post streptococcal glomerulonephritis is the most common of the post infectious renal disease in childhood, streptococcal pharyngitis is more common in the winter.
Urinary symptoms:
Decreased urine output
Bloody or brown- colored urine
Malaise
Mild headache
GIdisturbance
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
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Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
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Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
2. Acute glomerulonephritis is a common disease in
children and it is one of the diseases that are presented
commonly with hematuria which means red urine
(blood in urine). Acute Glomerulo Nephritis in all
probabilities results secondary to a proceeding
streptococcal (beta-hemolyticus type 12) infection of
throat or skin. A history of upper respiratory infection.
3. Acute Nephritis or glomerulonephritis is an infective
renal disease characterized by sudden onset of
hematuria, oliguria, edema and hypertension.
4. Acute glomerulonephritis is an immune – mediated
inflammatory disease of the capillary loops in the renal
glomeruli. The antigen – antibody complex deposition
within the glomeruli results in glomerular injury which
is manifested as hematuria, oliguria, edema and
hypertension.
5. The Kidneys are paired reddish and bean shaped organs
located in the peritoneum and the posterior wall of the
abdomen. The kidneys are located between the levels
of the last thoracic and third lumbar vertebrae, a
position where they are partially protected by the
eleventh and twelfth pairs of ribs. The right kidney is
slightly lower than the left because the liver occupies
considerable space on the right side superior to the
kidney.
6.
7.
8. 1.Homostasis function-
Excreting wastes and foreign substances
Maintenance of water balance
Maintenance of electrolyte balance
Maintenance of acid base balance
2.Hemopoietic function
3.Endocrine function
4.Regulation of blood pressure
5.Regulation of blood calcium level
9. More common in male than females.
Most common in preschool and early school age
children with a peak age of onset of 6-7 years.
Rare in children under two years of age.
On average responsible for 2 to 4% of pediatric
admissions in India.
Accounts for about 90% of renal diseases in childhood
Varies with the prevalence of nephritogenic strains of
streptococci and the likelihood of cross – infection.
10. 1.Presumed cause – antigen – antibody reaction
secondary to an infection in the body.
2.Initial infection:
Usually either an upper respiratory infection or a skin
infection, usually one to 3 weeks before the onset of
symptoms
Most frequent causative agent – nephritogenic strains
of group - A beta – haemolytic streptococcus (type 12),
acute post – streptococcal glomerulonephritis (APSGN)
is the most common.
11. Most cases are post infectious and have been associated
with
-Pneumococcal
-Viral infection
-Acute post streptococcal glomerulonephritis is the most
common of the post infectious renal disease in
childhood.
-Streptococcal pharyngitis is more common in the winter.
12. Urinary symptoms:
Decreased urine output
Bloody or brown – coloured urine.
Oedema:
Present in most patients
Usually mild.
Often manifested by Periorbital oedema in the morning
May appear only as rapid weight gain.
May be generalized and influenced by posture.
13. Hypertension:
Present in over 50 per cent of patients.
Usually mild.
Rise in blood pressure may be sudden.
Usually appears during the first four to five days of the
illness.
Malaise
Mild headache
Gastrointestinal disturbances, especially anorexia and
vomiting, often with abdominal and long pain.
Pallor
Irritability
Lethargy
Dysuria
Fever
14. History of illness and physical examination help in
clinical diagnosis.
The confirmation of diagnosis is done by the following:
Urine examination:
It shows increased specific gravity, smoke dirty brown
colour urine with reduced total amount in 24 hrs. Mild
to moderate or severe albuminuria is detected.
Microscopic examination reveals presence of red cells,
WBCs, pus cells, epithelial cells and granular cast.
Proteinuria (3+ to 4+)
15. Blood examination:
Blood examination demonstrates increased level of
urea, creatine, ESR, ASO titer and anti – DNAase ‘B’.
There is decreased level of Hb%, serum complement
and albumin in blood. Hyponatremia and hyperkalemia
may occur in persistent oliguria.
Throat swab culture:
Throat swab culture may show presence of beta –
hemolyticus streptococcus in some children.
Chest X-ray:
It may show pulmonary congestion
16. AGN with impaired renal function as severe oliguria
and azotemia needs hospitalization for special
attention. Mild oliguria patients with normal blood
pressure can be managed at home with OPD – based
treatment.
Treatment is essentially symptomatic
Monitoring:
The patient should be monitored closely for the
presence of hematuria, decreased urinary output, and
signs of volume overload like edema, hypertension and
congestive heart failure.
17. Daily record the general condition, edema,
consciousness level, weight, heart rate, respiratory rate,
blood pressure, fluid intake and urinary output.
The kidney function tests must be monitored at regular
intervals.
Bed rest:
It is rarely indicated except during the acute phase
when complications of acute renal failure may be
present.
Protect the child from fatigue and contact with other
respiratory infections.
Position:
In congestive heart failure or hypertension, make the
patient lie in a propped up position and provide oxygen.
18. Diet:
Diet should be arranged with restriction of protein, salt
and fluid intake, till oliguria and increased blood urea
level persist.
Carbohydrate containing food to be allowed freely.
The diet of the patient need not be restricted routinely.
Fluid intake should be allowed in a calculated amount
(i.e., total amount of previous day urine output in 24
hrs plus insensible losses to be allowed to drink on that
day).
Daily weight recording is important to assess the
increase and decrease of edema.
19. Fluid balance:
Regular measurement of vital signs, body weight and
intake and output is essential to monitor the disease’s
progress and detect complications that may appear at
any time during the course of the disease.
A record of daily weight is the most useful means to
assess fluid balance and should be kept for children
treated at home and for those who are hospitalized.
Sodium and water restriction is useful when the output
is significantly reduced (< 2 to 3 dl/24hr.)
In these children the water allowed is equivalent to the
calculated insensible loss plus the volume of urine
excreted.
20. Diuretics are of limited value when severe renal failure
is not severe, diuretic therapy (usually furosemide
{lasix} is helpful if significant edema and fluid
overload are present.
Rarely, children with AGN develop ARF with oliguria
that significantly alters the fluid and electrolyte
balance.
Fluid restriction is needed in case of acute renal failure
when urine output is diminished.
21. Hypertension:
Acute hypertension must be anticipated and identified
early.
Blood pressure measurements are taken every 4 to 6
hrs.
Significant but not severe hypertension is controlled
with loop diuretics.
Other antihypertensive drugs, such as calcium channel
blockers, beta blockers, or angiotensin – converting
enzyme inhibitors, may be needed in severe cases.
Dialysis:
May be required in patient with severe and prolonged
oliguria or anuria,and renal failure.
22. Penicillin:
Administered of antibiotic (preferably Penicillin) is needed
for 7 to 10 days to eradicate streptococci in the throat or
skin.
Anti hypertensive (nifedipine, atenolol) and diuretics are
used to control hypertension and its consequences.
Magnesium sulphate may be prescribed in the
encephalopathy to reduce cerebral edema.
Sedatives (diazepam) may be required in restless patients.
Management of complication like CCF, hypertensive
encephalopathy, etc should be done promptly to prevent life
threatening outcome. Dopamine infusion, steroid therapy
and respiratory support may require for some patients.
23. Impaired urinary elimination related to glomerular
dysfunction.
Infection related to group A beta- haemolytic streptococcus
pharyngitis, upper respiratory infection.
Fluid volume excess related to altered renal function (or)
diminished glomerular filtration increased Na+ retention.
Activity intolerance related to edema.
Altered skin integrity related to edema
Altered nutritional, less than body requirement, related to
albuminuria and GI disturbances.
Fear and anxiety related to disease processes.
High risk for seizure activity related to hypertensive
encephalopathy.
Knowledge deficit regarding care of the child with renal
disease and continuation of care at home.
24. 1.Hypertensive encephalopathy:
Manifestations:
Restlessness
Convulsions
Vomiting
Severe headache
Visual disturbance
Cause – probably ischemia secondary to vasospasm.
Duration:
Usually one to two days.
Ends spontaneously with decreased blood pressure.
2.Congestive heart failure:
Cardiac failure may occur due to persistent hypertension,
hypervolemia and peripheral vasoconstriction.
25. Manifestation:
Dyspnoea
Tachycardia
Liver engorgement.
Duration:
Variable
Usually subsides rapidly with the onset the fall in blood
pressure.
3.Uraemia (rare):
Manifestation:
Evidence of acidosis
26. Drowsiness
Coma
Muscular twitching
Convulsions.
4.Anaemia: usually caused by hyperyolaemia rather than
a loss of red blood cells in the urine.
5.Renal failure may occur with severe oliguria or anuria
or increased B.P
It may occur in two phases:-
First phase: this stage of edema with oliguria may last
for 5 – 10 days.
Second phase: this stage of dieresis starts with the
increased of urine and decreased edema.
27.
28. Hydronephrosis is a condition in which one or both of
the kidneys become stretched and swollen. This is
usually because:
There is a blockage somewhere in the urinary system
which is the usual cause, or urine is flowing from the
bladder back to the kidneys
It can sometimes cause a pain in the side, or there may
be no symptoms at all.
29. Hydronephrosis is distension and dilation of the renal
pelvis and calyces, usually caused by obstruction of the
free flow of urine from the kidney, leading to
progressive atrophy of the kidney.
30.
31. The signs and symptoms of Hydronephrosis depend upon
whether the obstruction is acute or chronic, partial or
complete, unilateral or bilateral. Unilateral Hydronephrosis
may occur without any symptoms.
Asymptomatic (in some cases)
Pain is felt in the renal area
Hematuria
Urinary infection, dysuria frequency
Renal calculi
Azotemia
Some large Hydronephrosis can be palpable
32.
33. History collection
Physical examination: An enlarged kidney may be
palpable on examination. Suprapubic tenderness along with
a palpable bladder is strongly suggestive of acute urinary
retention
Blood tests can show raised Creatinine and electrolyte
imbalance.
Urinalysis may show an elevated pH due to the secondary
destruction of nephrons within the affected kidney.
Ultrasound allows for visualization of the ureters and
kidneys and can be used to assess the presence of
Hydronephrosis .
34. IVU (intravenous urogram) is useful for assessing the
position of the obstruction.
CT 99% of stones are visible on CT and therefore CT
is becoming a common choice of initial investigation.
35. MEDICAL MANAGEMENT
Treatment of Hydronephrosis focuses upon
The removal of the obstruction
Drainage of the urine that has accumulated behind the
obstruction.
The antibiotics are used to prevent the Hydronephrosis
from causing kidney infections.
36. Nephrostomy
Acute obstruction of the upper urinary tract is usually
treated by the insertion of a Nephrostomy (an artificial
opening created between the kidney and the skin which
allows for the drainage of urine directly from the upper
part of the urinary system) tube.
Ureteric Stent
Chronic upper urinary tract obstruction is treated by the
insertion of a Ureteric stent (a thin tube inserted into
the ureter to prevent or treat obstruction of the urine
flow from the kidney)
38. Pyeloplasty
Pyeloplasty is the surgical reconstruction of the renal
pelvis to drain and decompress the kidney. Most
commonly it is performed to treat an uretero-pelvic
junction obstruction if residual renal function is
adequate.
Suprapubic Catheter
Lower urinary tract obstruction is usually treated by
insertion of a urinary catheter or a suprapubic catheter.
Fetal surgery for congenital Hydronephrosis.
Fetal surgical treatment is done for the correction of
posterior urethral valve obstruction and ureteropelvic
junction obstruction.
40. ASSESSMENT
History
Elicit a careful history about urinary patterns to determine
a history of burning sensations, abnormal color, and
frequency of urination.
Determine any recent history of mild or severe renal or
flank pain that radiates to the groin.
Ask about vomiting, nausea, or abdominal fullness. Ask a
male patient if he has had prostate difficulties and urinary
difficulties.
Physical Examination
Inspect the flank area for asymmetry, which indicates the
presence of a renal mass.
Inspect the male urethra for stenosis, injury, or phimosis.
41. Inspect and palpate for vaginal, uterine, and rectal
lesions in females. When the flank area is palpated, you
may feel a large fluctuating soft mass in the kidney area
that represents the collection of urine in the renal
pelvis.
Palpate the abdomen to help identify tender areas.
If the Hydronephrosis is the result of bladder
obstruction, markedly distended urinary bladder may
be felt.
Gentle pressure on the urinary bladder may result in
leaking urine from the urethra because of bladder
overflow.
42. PRE-OPERATIVE NURSING DIAGNOSIS
Hyperthermia related to infectious process.
Impaired nutritional status less than body requirement
related to hospitalization.
Disturbed elimination pattern incontinence of urine and
related to retention of urine
Deficient knowledge of parents related to the plan of
treatment, surgical procedure and prevention of
complications.
Disturbed family process related to hospitalization of the
child.
High risk for urinary tract infection related to presence of
urinary obstruction.
43. POST-OPERATIVE NURSING DIAGNOSIS
Ineffective airway clearance related to effects of
anesthesia, and pain
Acute pain related to incision, and the surgical
procedure
Impaired physical mobility of the upper extremities
related to surgery
Risk for imbalanced fluid volume related to the surgical
procedure
Deficient knowledge of home care procedures
Risk for infection related to the presence of surgical
wound.
44. Teach the importance of adequate fluids.
Explain the importance of notifying the physician at
the first signs of inability to void or of urinary
infection, such as burning or painful urination, cloudy
urine, rusty or smoky urine, blood-tinged urine, foul
odor, flank pain, or fever.
45. Early detection and prompt treatment has good
prognosis. Left untreated, bilateral obstruction
(occurring to both kidneys rather than one) has a poor
prognosis.
46. Text book of pediatric nursing, editors by “wong and
whaley’s”, published by “n.r.broyhers”, 4th edition,
page no:1242-1246.
Dorothy r. marlow, “text book of pediatric nursing” 6th
edition, published by elsevien, page no: 284-290.
Text book of “essential pediatric nursing”, editors by
“piyush gupta”, published by “a.p. jain and co”, 1st
edition, page no: 300- 301.
The short text book of “pediatric nursing”, editors by
“suraj gupte”, published by “jaypee brothers”, 10th
edition, page no: 433-434.
47. A text book of pediatric nursing, editor by “parul
datta”, published by “ jaypee”, 2nd edition, page no:
362-364
The lippincott manual of pediatric nursing, editor by
“barbara f. weller”, published by “chapman and hall”,
8th edition, page no: 777-778.
Nursing care plans for newborns and children, editor by
“ micheke knoll puzas”, published by “ mosby”, page
no: 355 – 357.
Assuma beevi.t.m., “text book of pediatric nursing”,
published by elsevien, page no: 307-308