he kidneys are a vital organ critical to the human body. From filtering waste from blood to produce red blood cells, it serves a crucial role. With cells and tissue that work together in synchronized form for common function
anatomy of stomach,functions of stomach, location, shape position and parts of stomach,orifices of stomach, curvature of stomach, relations of stomach, blood supply, innervation, lymphatic drainage, clinical relation , GERD, peptic ulcer,
It includes structure of stomach, stomach bed, function and internal structure.
Give your like & share with other nursing students.
The stomach is an important organ and the most dilated portion of the digestive system. The esophagus precedes it, and the small intestine follows. It is a large, muscular, and hollow organ allowing for a capacity to hold food. It is comprised of 4 main regions, the cardia, fundus, body, and pylorus.
rectus sheath, the sheath covering rectus muscle of anterior abdominal wall, formation of the sheath, the muscles involved in ts formation, and the contents the sheath is covering
Human Anatomy and Physiology-II:
Endocrine System:
Classification of hormones, mechanism of hormone action, structure and functions of pituitary gland, thyroid gland, parathyroid gland,
adrenal gland, pancreas, pineal gland, thymus and their disorders.
The blood vessels are the components of the circulatory system that transport blood throughout the human body. These vessels transport blood cells, nutrients, and oxygen to the tissues of the body. They also take waste and carbon dioxide away from the tissues.
6. ANATOMY OF THE KIDNEY, URETER & POSTERIOR.pdfmarkmuiruri581
Anatomy of Urinary System
Urinary System Organs
Kidneys (2)
Ureters (2)
Urinary bladder
Urethra
Kidney Functions
Control blood volume and composition.
Filter blood plasma, eliminate wastes.
Regulate blood volume, pressure, and fluid osmolarity.
Secrete renin and erythropoietin (EPO).
Regulate PCO2, acid-base balance.
Synthesize calcitriol (Vitamin D).
Detoxify free radicals and drugs.
Perform gluconeogenesis.
Kidney Anatomy
Renal Fascia: Attaches to the abdominal wall.
Adipose Capsule: Provides fat cushioning for the kidney.
Renal Capsule: Fibrous sac that protects from trauma and infection.
Renal Sinus: Contains blood vessels, lymphatics, nerves, and urine-collecting structures.
Renal Parenchyma:
Outer Cortex
Inner Medulla
Renal Pyramids: Extensions of cortex dividing medulla.
Renal Columns: Connect cortex and medulla.
Renal Pelvis: Collects urine from pyramids.
Ureter: Carries urine to the bladder.
Remember, the kidneys play a crucial role in maintaining homeostasis by regulating fluid balance, electrolytes, and waste elimination. Ureter Anatomy
Overview
The ureters are bilateral, muscular, tubular structures responsible for transporting urine from the kidneys to the urinary bladder for storage and eventual excretion.
After blood filtration in the kidneys, the filtrate undergoes reabsorption and exudation along the convoluted tubules.
The urine then passes through the collecting tubules and enters the collecting ducts.
From the collecting ducts, it flows through the calyces into the renal pelvis, marking the beginning of the ureters.
Histology of Ureter
The lumen of each ureter is lined by a mucosal layer of urothelium (transitional epithelium).
The ureteral wall contains two muscular layers:
Longitudinal layer
Circular layer
In the lower segment of the ureters, an additional longitudinal layer is found proximal to the bladder.
Urine is propelled along the ureters by peristaltic motions initiated by pacemaker cells in the proximal renal pelvis.
Relations
Both ureters pass inferiorly over the abdominal surface of the psoas major muscle.
The right ureter travels posterior to the duodenum and is crossed by branches of the superior mesenteric vessels.
The left ureter is also posterior to the psoas major and is crossed by branches of the inferior mesenteric vessels.
Posterior Abdominal Wall
Construction
Bony: Extends from the 12th rib above to the pelvic brim below.
Muscular part: Composed of muscles and fasciae.
Fasciae: Provides stability and support for retroperitoneal organs, vessels, and nerves.
Remember, understanding the anatomy of the ureter and posterior abdominal wall is essential for clinical pracPosterior Abdominal Wall
Construction
Bony: Extends from the 12th rib above to the pelvic brim below.
Muscular part: Composed of muscles and fasciae.
Fasciae: Provides stability and support for retroperitoneal organs, vessels, and nerves.
Muscles of Posterior Abdominal Wall
Psoas Major:
Origin: Continuously attached from T12 (lower border) to L5
anatomy of stomach,functions of stomach, location, shape position and parts of stomach,orifices of stomach, curvature of stomach, relations of stomach, blood supply, innervation, lymphatic drainage, clinical relation , GERD, peptic ulcer,
It includes structure of stomach, stomach bed, function and internal structure.
Give your like & share with other nursing students.
The stomach is an important organ and the most dilated portion of the digestive system. The esophagus precedes it, and the small intestine follows. It is a large, muscular, and hollow organ allowing for a capacity to hold food. It is comprised of 4 main regions, the cardia, fundus, body, and pylorus.
rectus sheath, the sheath covering rectus muscle of anterior abdominal wall, formation of the sheath, the muscles involved in ts formation, and the contents the sheath is covering
Human Anatomy and Physiology-II:
Endocrine System:
Classification of hormones, mechanism of hormone action, structure and functions of pituitary gland, thyroid gland, parathyroid gland,
adrenal gland, pancreas, pineal gland, thymus and their disorders.
The blood vessels are the components of the circulatory system that transport blood throughout the human body. These vessels transport blood cells, nutrients, and oxygen to the tissues of the body. They also take waste and carbon dioxide away from the tissues.
6. ANATOMY OF THE KIDNEY, URETER & POSTERIOR.pdfmarkmuiruri581
Anatomy of Urinary System
Urinary System Organs
Kidneys (2)
Ureters (2)
Urinary bladder
Urethra
Kidney Functions
Control blood volume and composition.
Filter blood plasma, eliminate wastes.
Regulate blood volume, pressure, and fluid osmolarity.
Secrete renin and erythropoietin (EPO).
Regulate PCO2, acid-base balance.
Synthesize calcitriol (Vitamin D).
Detoxify free radicals and drugs.
Perform gluconeogenesis.
Kidney Anatomy
Renal Fascia: Attaches to the abdominal wall.
Adipose Capsule: Provides fat cushioning for the kidney.
Renal Capsule: Fibrous sac that protects from trauma and infection.
Renal Sinus: Contains blood vessels, lymphatics, nerves, and urine-collecting structures.
Renal Parenchyma:
Outer Cortex
Inner Medulla
Renal Pyramids: Extensions of cortex dividing medulla.
Renal Columns: Connect cortex and medulla.
Renal Pelvis: Collects urine from pyramids.
Ureter: Carries urine to the bladder.
Remember, the kidneys play a crucial role in maintaining homeostasis by regulating fluid balance, electrolytes, and waste elimination. Ureter Anatomy
Overview
The ureters are bilateral, muscular, tubular structures responsible for transporting urine from the kidneys to the urinary bladder for storage and eventual excretion.
After blood filtration in the kidneys, the filtrate undergoes reabsorption and exudation along the convoluted tubules.
The urine then passes through the collecting tubules and enters the collecting ducts.
From the collecting ducts, it flows through the calyces into the renal pelvis, marking the beginning of the ureters.
Histology of Ureter
The lumen of each ureter is lined by a mucosal layer of urothelium (transitional epithelium).
The ureteral wall contains two muscular layers:
Longitudinal layer
Circular layer
In the lower segment of the ureters, an additional longitudinal layer is found proximal to the bladder.
Urine is propelled along the ureters by peristaltic motions initiated by pacemaker cells in the proximal renal pelvis.
Relations
Both ureters pass inferiorly over the abdominal surface of the psoas major muscle.
The right ureter travels posterior to the duodenum and is crossed by branches of the superior mesenteric vessels.
The left ureter is also posterior to the psoas major and is crossed by branches of the inferior mesenteric vessels.
Posterior Abdominal Wall
Construction
Bony: Extends from the 12th rib above to the pelvic brim below.
Muscular part: Composed of muscles and fasciae.
Fasciae: Provides stability and support for retroperitoneal organs, vessels, and nerves.
Remember, understanding the anatomy of the ureter and posterior abdominal wall is essential for clinical pracPosterior Abdominal Wall
Construction
Bony: Extends from the 12th rib above to the pelvic brim below.
Muscular part: Composed of muscles and fasciae.
Fasciae: Provides stability and support for retroperitoneal organs, vessels, and nerves.
Muscles of Posterior Abdominal Wall
Psoas Major:
Origin: Continuously attached from T12 (lower border) to L5
Anatomy of the urinary system
Anatomy of the kidneys
Anatomy of the nephron
Anatomy of the ureters
Anatomy of the urinary bladder
Anatomy of the urethra; male and female urethra
he spleen is a fist-sized organ found in the upper left side of your abdomen, next to your stomach and behind your left ribs. It's an important part of your immune system but you can survive without it. This is because the liver can take over many of the spleen's functions
Group Dynamic(presentation for nursing management)ABHIJIT BHOYAR
Group dynamics is a system of behaviors and psychological processes occurring within a social group (intragroup dynamics), or between social groups (intergroup dynamics)
the practice of training people to obey rules and behave well.
the practice of training your mind and body so that you control your actions and obey rules; a way of doing this
Isoenzymes (or isozymes) are a group of enzymes that catalyze the same reaction but have different enzyme forms and catalytic efficiencies. Isozymes are usually distinguished by their electrophoretic mobilities.
An enzyme is a biological catalyst and is almost always a protein. It speeds up the rate of a specific chemical reaction in the cell. The enzyme is not destroyed during the reaction and is used over and over.
A complete cholesterol test — also called a lipid panel or lipid profile — is a blood test that can measure the amount of cholesterol and triglycerides in your blood
Cholesterol is a waxy substance found in your blood. Your body needs cholesterol to build healthy cells, but high levels of cholesterol can increase your risk of heart disease.
Lipid metabolism entails the oxidation of fatty acids to either generate energy or synthesize new lipids from smaller constituent molecules. Lipid metabolism is associated with carbohydrate metabolism,
LIPIDS-Digestion and absorption of Lipids.pptxABHIJIT BHOYAR
The digestion of lipids begins in the oral cavity through exposure to lingual lipases, which are secreted by glands in the tongue to begin the process of digesting triglycerides.
The term essential fatty acids (EFA) refers to those polyunsaturated fatty acids (PUFA) that must be provided by foods because these cannot be synthesized in the body yet are necessary for health
Fatty acids are the building blocks of the fat in our bodies and in the food we eat. During digestion, the body breaks down fats into fatty acids, which can then be absorbed into the blood. Fatty acid molecules are usually joined together in groups of three, forming a molecule called a triglyceride.
Once the egg has left the ovary it can be fertilized and implant itself in the lining of the uterus. The main function of the uterus is to nourish the developing fetus prior to birth.
If you like share this PPT presentation to nursing students. The pancreas is an organ and a gland. Glands are organs that produce and release substances in the body. The pancreas performs two main functions: Exocrine function: Produces substances (enzymes) that help with digestion.
The Popliteal Fossa is a diamond-shaped space behind the knee joint. It is formed between the muscles in the posterior compartments of the thigh and leg. This anatomical landmark is the major route by which structures pass between the thigh and leg.
The femoral triangle is a wedge-shaped area located within the superomedial aspect of the anterior thigh. The femoral triangle is a hollow region located in the supero-medial part of the anterior thigh.
This topic is related to the joints.
it is a type of synovial joint.
it is a ball and socket type.
This is very sensative joint and easy to have fracture to this part.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
Factory Supply Best Quality Pmk Oil CAS 28578–16–7 PMK Powder in Stockrebeccabio
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MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
2. Introduction
• The closely packed structure and numerous functions of the kidney illustrate the
beautiful workmanship of our creator.
• It not only applies to the kidney but to each and every part of our body
• The kidneys are also called rene’s from which we have the derivative renal; and
nephron from which we have the terms nephron, nephritis, etc
4. Location
• The kidneys occupy the epigastric, hypochondriac, lumbar and umbilical regions.
• Vertically, they extend from the upper border of twelfth thoracic vertebra to the
centre of the body of third lumbar vertebra.
5. • The right kidney is slightly lower than
the left, and the left kidney is a little
nearer to the median plane than the right.
• The transpyloric plane passes through
the upper part of the hilus of the right
kidney, and through the lower part of the
hilus of the left kidney.
6. Shape, Size, Weight and Orientation
• Each kidney is about 11 cm long, 6 cm broad, and 3 cm thick.
• The left kidney is a little longer and narrower than the right kidney.
• On an average, the kidney weighs 150 g in males and 135 g in females.
• The kidneys are reddish brown in colour
7. EXTERNAL FEATURES OF KIDNEY
• Each kidney is bean-shaped.
• It has
Upper and lower poles,
Medial and lateral borders, and
Anterior and posterior surfaces.
8. Pole
• The upper pole is broad and is in
close contact with the
corresponding suprarenal gland.
• The lower pole is pointed
9. Surfaces
• The anterior surface is said to be
irregular and the posterior surface
flat, but it is often difficult to
recognize the anterior and posterior
aspects of the kidney by looking at
the surfaces.
10. Borders
• The lateral border is convex.
• The medial border is concave.
• Its middle part shows a
depression, the hilus or hilum
11. Hilum
The following structures are seen in the hilum from anterior side to
posterior side.
1. The renal vein
2. The renal artery
3. The renal pelvis, which is the expanded upper end of the ureter
12. RELATIONS OF THE KIDNEYS
• The kidneys are retroperitoneal organs and are only partly covered by
peritoneum anteriorly.
13. Relations Common to the Two Kidneys
1. The upper pole of each kidney is related to the corresponding suprarenal gland.
The lower poles lie about 2.5 cm above the iliac crests.
2. The medial border of each kidney is related to:
a) The suprarenal gland, above the hilus, and
b) b. To the ureter below the hilus.
14. 3. Posterior relations: The posterior surfaces of both kidneys are related to the
following.
a) Diaphragm
b) Medial and lateral arcuate ligaments
c) Psoas major
d) Quadratus lumborum
e) Transversus abdominis
f) Subcostal vessels
g) Subcostal, iliohypogastric and ilioinguinal nerves.
15.
16. • In addition, the right kidney is related to twelfth rib, and the left
kidney to eleventh and twelfth ribs.
4. Hilum
17. Other Relations of the Right Kidney
Anterior Relations
1. Right suprarenal gland
2. Liver
3. Second part of duodenum
4. Hepatic flexure of colon
5. Small intestine
• Out of these, the hepatic and intestinal surfaces are covered by peritoneum. The
lateral border of the right kidney is related to the right lobe of the liver and to the
hepatic flexure of the colon.
18. Other Relations of the Left Kidney
Anterior Relations
1. Left suprarenal gland
2. Spleen
3. Stomach
4. Pancreas
5. Splenic vessels
6. Splenic flexure and descending colon
7. Jejunum
• Out of these, the gastric, splenic and jejunal surfaces are covered by peritoneum.
The lateral border of the left kidney is related to the spleen and to the
descending colon.
19.
20.
21. CAPSULES OR COVERINGS OF
KIDNEY
• This is a thin membrane which closely invests the kidney and lines the
renal sinus.
• Normally, it can be easily stripped off from the kidney, but in certain
diseases, it becomes adherent and cannot be stripped
The Fibrous Capsule
22. Perirenal or Perinephric Fat
• This is a layer of adipose tissue lying outside the fibrous capsule.
• It is thickest at the borders of the kidney and fills up the extra space in
the renal sinus.
23. Renal Fascia
• The perirenal fascia was originally described as being made up of two
separate layers
• Posterior layer was called fascia of Zuckerkandal and anterior layer as
fascia of Gerota.
24. Pararenal or Paranephric Body (Fat)
• It consists of a variable amount of fat lying outside the renal fascia.
• It is more abundant posteriorly and towards the lower pole of the
kidney.
• It fills up the paravertebral gutter and forms a cushion for the kidney
25. STRUCTURE
An outer—reddish brown cortex.
An inner—pale medulla.
A space—the renal sinus
Naked eye examination of a coronal section of the kidney shows:
26.
27. • The renal cortex is divisible into two parts.
a) Cortical arches or cortical lobules, which form caps over the bases
of the pyramids.
b) Renal columns, which dip in between the pyramids
• Each pyramid along with the overlying cortical arch forms a lobe of
the kidney.
28. • The renal sinus is a space that extends into the kidney from the hilus. It contains:
a. Branches of the renal artery.
b. Tributaries of the renal vein
c. The renal pelvis.
• The pelvis divides into 2 to 3 major calyces, and these in their turn divide into 7 to
13 minor calyces. Each minor calyx (kalyx = cup of a flower) ends in an expansion
which is indented by one to three renal papillae
29. Structure of Uriniferous Tubule
• Each kidney is composed of one to three million uriniferous tubules.
• Each tubule consists of two parts which are embryologically distinct
from each other.
• These are as follows.
• The excretory part, called the nephron, which elaborates urine
30.
31. • Nephron is the functional unit of the kidney, and comprises:
a. Renal corpuscle or malpighian corpuscle (for filtration of substances from the
plasma) made up of glomerulus (Latin ball), a tuft of capillaries and Bowman’s
capsule.
b. Renal tubule (for selective resorption of substances from the glomerular
filtrate) made up of the proximal convoluted tubule, loop of Henle with its
descending and ascending limbs, and the distal convoluted tubule
32.
33. • The collecting part begins as a junctional tubule from the distal
convoluted tubule.
• Many tubules unite together to form the ducts of Bellini which open
into the minor calyces through the renal papillae
34. • Juxtaglomerular apparatus is formed at the vascular pole of glomerulus which is
intimately related to its own ascending limb of the Henle’s loop near the distal
convoluted tubule.
The apparatus consists of:
a. Macula densa, formed by altered cells of the distal convoluted tubule.
b. Juxtaglomerular cells, formed by the epithelioid cells in the media of the
afferent arteriole.
c. Some agranular cells between macula densa and the glomerulus proper.
38. Applied anatomy
• Polycystic kidney
• The common diseases of kidney are nephritis, pyelonephritis,
tuberculosis of kidney, renal stones and tumours
39. FUNCTIONS OF KIDNEY
• Remove waste products from the body.
• Remove drugs from the body.
• Balance the body's fluids.
• Release hormones that regulate blood pressure.
• Produce an active form of vitamin D that promotes strong, healthy bones.
• Control the production of red blood cells.