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Topics 3.3 & 7.1Nucleic Acids IB Biology
Where can you find it? Inside the cell - nucleus, chloroplasts and mitochondria Chromosomes are made of DNA
Nucleic Acids Polymers:  DNA (deoxyribonucleic acid)  RNA (ribonucleic acid) Units: nucleotides Nucleotide: sugar + nitrogenous base + phosphate
Parts of a Nucleotide Phosphate Sugar: Ribose or Deoxyribose (both pentoses) Nitrogenous Bases:  	- Purines (double rings): Adenine + Guanine 	- Pyrimidines (single ring): Cytosine, Thymine, Uracil (RNA only)
Structure of DNA ,[object Object]
James Watson, Francis Crick and Maurice Wilkins received a NOBEL PRIZE
Watson, Crick and Wilkins used unpublished data from Rosalind Franklin’s research obtained without her knowledge and used without her consent.	- She was misrepresented and unrecognized  	- She died of cancer in 1958 ,[object Object],	- 4 nucleotides - A, T, G, C   	- in 2 polynucleotide strands     - strands run antiparallel - [5'-----3'] - held together via weak H-Bonds & complimentary base pairing (A-T and C-G)
DNA is double-stranded, withcomplementary base pairing
Observe  - hydrogen bonds - complementary base pairing : A – T C – G  - covalent bonds between 2 nucleotides (formed through condensation)
Counting Carbons... Anti-parallel strands One side 5’  3’ Other side 3’  5’
DNA Structure In eukaryotes it is always associated with proteins NUCLEOSOMES = DNA wrapped around 8 histones (proteins) Help compact DNA  Help control DNA transcription
Single copy x Highly repetitive sequences Much of DNA in eukaryotes = repetitive base sequences, which are not translated (satellite DNA) = 5-300 bases / repeated as many as 10,000x 5-45% of DNA = function not clear Single copy/unique genes = actually code for something (small proportion)
DNA’s job Stores information It has the code for all 20 amino acids Mutation: changes in the base sequence  primary structure of a protein is altered (changing its shape) Can be harmful, neutral or beneficial  Important: create variation – basis of natural selection

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3.3 7.1 Dna Structure

  • 1. Topics 3.3 & 7.1Nucleic Acids IB Biology
  • 2. Where can you find it? Inside the cell - nucleus, chloroplasts and mitochondria Chromosomes are made of DNA
  • 3. Nucleic Acids Polymers: DNA (deoxyribonucleic acid) RNA (ribonucleic acid) Units: nucleotides Nucleotide: sugar + nitrogenous base + phosphate
  • 4. Parts of a Nucleotide Phosphate Sugar: Ribose or Deoxyribose (both pentoses) Nitrogenous Bases: - Purines (double rings): Adenine + Guanine - Pyrimidines (single ring): Cytosine, Thymine, Uracil (RNA only)
  • 5.
  • 6. James Watson, Francis Crick and Maurice Wilkins received a NOBEL PRIZE
  • 7.
  • 8. DNA is double-stranded, withcomplementary base pairing
  • 9. Observe - hydrogen bonds - complementary base pairing : A – T C – G - covalent bonds between 2 nucleotides (formed through condensation)
  • 10. Counting Carbons... Anti-parallel strands One side 5’  3’ Other side 3’  5’
  • 11. DNA Structure In eukaryotes it is always associated with proteins NUCLEOSOMES = DNA wrapped around 8 histones (proteins) Help compact DNA Help control DNA transcription
  • 12. Single copy x Highly repetitive sequences Much of DNA in eukaryotes = repetitive base sequences, which are not translated (satellite DNA) = 5-300 bases / repeated as many as 10,000x 5-45% of DNA = function not clear Single copy/unique genes = actually code for something (small proportion)
  • 13. DNA’s job Stores information It has the code for all 20 amino acids Mutation: changes in the base sequence  primary structure of a protein is altered (changing its shape) Can be harmful, neutral or beneficial Important: create variation – basis of natural selection
  • 14.
  • 15. RNAr: ribosomal  makes up ribosomes
  • 16.