This document is a technical seminar report submitted by N. Shyam Kumar to the Department of Electronics and Communication Engineering at SVS Institute of Technology. The report discusses brain-computer interfaces, including their working architecture and types. It covers invasive BCIs implanted in the brain, partially invasive BCIs implanted in the skull, and non-invasive BCIs using EEG. It also discusses early animal research with BCIs implanted in monkeys and rats.
A Brain-Computer Interface (BCI) provides a new communication channel between the human brain and the computer. The 100 billion neurons communicate via minute electrochemical impulses, shifting patterns sparking like fireflies on a summer evening, that produce movement, expression, words. Mental activity leads to changes of electrophysiological signals.
As the power of modern computers grows alongside our understanding of the human brain, we move ever closer to making some pretty spectacular science fiction into reality. Imagine transmitting signals directly to someone's brain that would allow them to see, hear or feel specific sensory inputs. Consider the potential to manipulate computers or machinery with nothing more than a thought. It isn't about convenience, for severely disabled people, development of a brain-computer interface (BCI) could be the most important technological breakthrough in decades.
A Brain-computer interface, sometimes called a direct neural interface or a brain-machine interface, is a direct communication pathway between a brain and an external device. It is the ultimate in development of human-computer interfaces or HCI. BCIs being the recent development in HCI there are many realms to be explored. After experimentation three types of BCIs have been developed namely Invasive BCIs, Partially-invasive BCIs, Non-invasive BCIs.
Presentation on Brain Computer Interface. It describes how our brain is used as a signaling mechanism for computer. different types of BCIs and its applications.
Brain Computer Interface (BCI) aims at providing an alternate means of communication and control to people with severe cognitive or sensory-motor disabilities. These systems are based on the single trial recognition of different mental states or tasks from the brain activity. This paper discusses the major components involved in developing a Brain Computer Interface system which includes the modality to obtain brain signals and its related processing methods.
Brain computer interface is a direct connection between computer an human brain.
The brain computer can lead to many applications especially for disabled person.
Brain computer interface applications utilize the brain and its newrons system functions.
A Brain-Computer Interface (BCI) provides a new communication channel between the human brain and the computer. The 100 billion neurons communicate via minute electrochemical impulses, shifting patterns sparking like fireflies on a summer evening, that produce movement, expression, words. Mental activity leads to changes of electrophysiological signals.
As the power of modern computers grows alongside our understanding of the human brain, we move ever closer to making some pretty spectacular science fiction into reality. Imagine transmitting signals directly to someone's brain that would allow them to see, hear or feel specific sensory inputs. Consider the potential to manipulate computers or machinery with nothing more than a thought. It isn't about convenience, for severely disabled people, development of a brain-computer interface (BCI) could be the most important technological breakthrough in decades.
A Brain-computer interface, sometimes called a direct neural interface or a brain-machine interface, is a direct communication pathway between a brain and an external device. It is the ultimate in development of human-computer interfaces or HCI. BCIs being the recent development in HCI there are many realms to be explored. After experimentation three types of BCIs have been developed namely Invasive BCIs, Partially-invasive BCIs, Non-invasive BCIs.
Presentation on Brain Computer Interface. It describes how our brain is used as a signaling mechanism for computer. different types of BCIs and its applications.
Brain Computer Interface (BCI) aims at providing an alternate means of communication and control to people with severe cognitive or sensory-motor disabilities. These systems are based on the single trial recognition of different mental states or tasks from the brain activity. This paper discusses the major components involved in developing a Brain Computer Interface system which includes the modality to obtain brain signals and its related processing methods.
Brain computer interface is a direct connection between computer an human brain.
The brain computer can lead to many applications especially for disabled person.
Brain computer interface applications utilize the brain and its newrons system functions.
Brain Computer Interface and Artificial Brain: Interfacing Microelectronics a...Lk Rigor
Signals from the brain can be processed to improve quality of human life. Such is the aim of biotechnology, to harness cellular and biomolecular processes to develop technologies that can improve human life. How can brain computer interface (BCI) and artificial brain achieve that?
This PPT contains the basic information regarding the Brain Computer Interface technology. You can find the detailed presentation file here under the heading "Brain Computer Interface WORD FILE"
What is Brain Computer Interface?, How it Works?, On what it works?
It Is about the controlling computers or any programmable electronic device using brain, by implanting electrodes in brain.
A brain–computer interface (BCI), sometimes called a mind-machine interface (MMI), direct neural interface (DNI), or brain–machine interface (BMI), is a direct communication pathway between an enhanced or wired brain and an external device. BCIs are often directed at researching, mapping, assisting, augmenting, or repairing human cognitive or sensory-motor functions.
BCI or DNI is a direct communication pathway between an enhanced or wired brain and an external device. DNIs are often directed at researching, mapping, assisting, augmenting, or repairing human cognitive or sensory-motor functions.
Powerpoint presentation on Brain Computer Interface (BCI), giving a brief introduction of the technology and then giving an overview of its working and its applications.
Each slide has notes added to it to help describe what the slide is about.
PPT of my technical Seminar titled Brain-computer interface (BCI). This is a collaboration between a brain and a device that enables signals from the brain to direct some external activity, such as control of a cursor or a prosthetic limb.
!
Brain Computer Interface Next Generation of Human Computer InteractionSaurabh Giratkar
In the area of HCI research the main focus is on defining new ways of human interaction with computer system. With the passes of time a number of inventions have been made in this field. In initial days we used only keyboards to access our computer system (e.g. in Unix Terminal). In Second phase, after invention of mouse and other pointing devices, we started using graphical user interface using pointing devices like mouse which make the use of computer more easy and comfortable. Nowadays we are using pressure-driven mechanism, i.e. touch screen, which is common at ATMs, Mobile phones and PDAs etc. Although it is not as common in daily works but the release of tablet PCs and its popularity shows that the day is not much far when we wouldn’t be having keyboards and mouse at all.
All of these inventions have been made for balancing the requirements of society and user. E.g. Games, Multimedia Applications etc are not possible using only-Keyboard so we need mouse driven system for such applications, similarly we cannot have large keyboard on mobile so we need a touch screen system for mobiles. In addition to these traditional HCI models, there are some more advance HCI technology too for adding more flexibility and hence making the product more useful. E.g. swap card system at office doors for attendance and ATM-swap card for shopping. Speech processing systems are also there where we can access our computer system using our speech. Fig 1 shows most popular traditional HCI system.
Introduce the concept of Brain-Computer Interface, and introduce a research paper about deployed Deep Learning in ECoG BCI and it shows the promising future in BCI development.
Medium post: https://medium.com/@bmwv12lmr/deep-learning-in-brain-computer-interface-bbef71343c4d
A brain–computer interface (BCI), is a direct communication pathway between the brain and an external device.
Ever wondered how it works? What are different types of BCI?
Find out more about Brain Computer Interface (BCI) in this presentation from Extentia Information Technology.
Brain Computer Interface and Artificial Brain: Interfacing Microelectronics a...Lk Rigor
Signals from the brain can be processed to improve quality of human life. Such is the aim of biotechnology, to harness cellular and biomolecular processes to develop technologies that can improve human life. How can brain computer interface (BCI) and artificial brain achieve that?
This PPT contains the basic information regarding the Brain Computer Interface technology. You can find the detailed presentation file here under the heading "Brain Computer Interface WORD FILE"
What is Brain Computer Interface?, How it Works?, On what it works?
It Is about the controlling computers or any programmable electronic device using brain, by implanting electrodes in brain.
A brain–computer interface (BCI), sometimes called a mind-machine interface (MMI), direct neural interface (DNI), or brain–machine interface (BMI), is a direct communication pathway between an enhanced or wired brain and an external device. BCIs are often directed at researching, mapping, assisting, augmenting, or repairing human cognitive or sensory-motor functions.
BCI or DNI is a direct communication pathway between an enhanced or wired brain and an external device. DNIs are often directed at researching, mapping, assisting, augmenting, or repairing human cognitive or sensory-motor functions.
Powerpoint presentation on Brain Computer Interface (BCI), giving a brief introduction of the technology and then giving an overview of its working and its applications.
Each slide has notes added to it to help describe what the slide is about.
PPT of my technical Seminar titled Brain-computer interface (BCI). This is a collaboration between a brain and a device that enables signals from the brain to direct some external activity, such as control of a cursor or a prosthetic limb.
!
Brain Computer Interface Next Generation of Human Computer InteractionSaurabh Giratkar
In the area of HCI research the main focus is on defining new ways of human interaction with computer system. With the passes of time a number of inventions have been made in this field. In initial days we used only keyboards to access our computer system (e.g. in Unix Terminal). In Second phase, after invention of mouse and other pointing devices, we started using graphical user interface using pointing devices like mouse which make the use of computer more easy and comfortable. Nowadays we are using pressure-driven mechanism, i.e. touch screen, which is common at ATMs, Mobile phones and PDAs etc. Although it is not as common in daily works but the release of tablet PCs and its popularity shows that the day is not much far when we wouldn’t be having keyboards and mouse at all.
All of these inventions have been made for balancing the requirements of society and user. E.g. Games, Multimedia Applications etc are not possible using only-Keyboard so we need mouse driven system for such applications, similarly we cannot have large keyboard on mobile so we need a touch screen system for mobiles. In addition to these traditional HCI models, there are some more advance HCI technology too for adding more flexibility and hence making the product more useful. E.g. swap card system at office doors for attendance and ATM-swap card for shopping. Speech processing systems are also there where we can access our computer system using our speech. Fig 1 shows most popular traditional HCI system.
Introduce the concept of Brain-Computer Interface, and introduce a research paper about deployed Deep Learning in ECoG BCI and it shows the promising future in BCI development.
Medium post: https://medium.com/@bmwv12lmr/deep-learning-in-brain-computer-interface-bbef71343c4d
A brain–computer interface (BCI), is a direct communication pathway between the brain and an external device.
Ever wondered how it works? What are different types of BCI?
Find out more about Brain Computer Interface (BCI) in this presentation from Extentia Information Technology.
Our company works on research and implementation of software and hardware solutions in the field of BCI related technology.
We teach people how to control different types of robots. We have created complete training course for beginners, what already allows us to control any object on 2D Euclidean plane.
Now we have begun works on collaborative and invariant learning rules such as quasi-quantum brain algorithm to allow people control any virtual or physical objects directly by the state of his mind.
A brain-computer interface (BCI), sometimes called a mind-machine interface (MMI), or sometimes called a direct neural interface (DNI), synthetic telepathy interface (STI) or a brain-machine interface (BMI), is a direct communication pathway between the brain and an external device. BCIs are often directed at assisting, augmenting, or repairing human cognitive or sensory-motor functions.Research on BCIs began in the 1970s at the University of California Los Angeles (UCLA) under a grant from the National Science Foundation, followed by a contract from DARPA.[1][2] The papers published after this research also mark the first appearance of the expression brain-computer interface in scientific literature.The field of BCI research and development has since focused primarily on neuroprosthetics applications that aim at restoring damaged hearing, sight and movement. Thanks to the remarkable cortical plasticity of the brain, signals from implanted prostheses can, after adaptation, be handled by the brain like natural sensor or effector channels.[3] Following years of animal experimentation, the first neuroprosthetic devices implanted in humans appeared in the mid-1990s.
This presentation is given in (2015) . As the power of modern computers grows alongside our understanding of the human brain, we move ever closer to making some pretty spectacular science fiction into reality.
BCI is a direct Neural Interface or Brain-Machine InterfaceJaahnvi Patel
BCI is technology to communicates the human brain directly to a computer without any physical contact. BCI is a fast-growing emergent technology in which researchers aim to build a direct channel between the human brain and the computer.
This presentation lists some brain-computer interface technologies that exist today and that could be attainable in future. At the end, philosophical comments about this kind of technology and transhumanism are purposed, in order to reveal the key difference between a humain brain and artificial intelligence.
This word file consists of a detailed introduction to the brain computer interface technology which is still a sophisticated technology. You can find its PPT under the heading "Brain Computer Interface PPT".
brain chip technology is a technology which involves communication based on neural activity generated by the brain. brain chip technology implements the brain computer interface.
Observability Concepts EVERY Developer Should Know -- DeveloperWeek Europe.pdfPaige Cruz
Monitoring and observability aren’t traditionally found in software curriculums and many of us cobble this knowledge together from whatever vendor or ecosystem we were first introduced to and whatever is a part of your current company’s observability stack.
While the dev and ops silo continues to crumble….many organizations still relegate monitoring & observability as the purview of ops, infra and SRE teams. This is a mistake - achieving a highly observable system requires collaboration up and down the stack.
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Brain Computer Interface
1. Department of ECE
1
SVS Institute of Technology
A Technical Seminar Report
On
“BRAIN COMPUTER INTERFACE”
Submitted in partial fulfillment of the requirements for
the award of the degree of
BACHELOR OF TECHNOLOGY
in
ELECTRONICS & COMMUNICATION ENGINEERING
from
JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY
HYDERABAD
by
N.SHYAM KUMAR
[10TK1A0479]
Under the esteemed guidance of
Mr. CH. RAMESH BABU M. Tech
Asst. Professor
E.C.E
DEPARTMENT OF ELECTRONICS & COMMUNICATION ENGINEERING
SVS INSTITUTE OF TECHNOLOGY
(Approved by AICTE, New Delhi & Affiliated to JNTU, Hyderabad & ISO 9001:2008 certified)
BHEEMARAM(V), HASANPARTHY(M),WARANGAL (Dt). A.P. India -506015
Ph: 0870-2453900, 6560833
www.svsit.ac.in
(2010-2014)
2. Department of ECE
2
SVS Institute of Technology
1. INTRODUCTION
A Brain-Computer Interface (BCI) provides a new communication channel between the
human brain and the computer. The 100 billion neurons communicate via minute
electrochemical impulses, shifting patterns sparking like fireflies on a summer evening, which
produce movement, expression, and words. Mental activity leads to changes of
electrophysiological signals. The BCI system detects such changes and transforms it into a
control signal .In the case of cursor control, for example, the signal is transmitted directly from
the brain to the mechanism directing the cursor, rather than taking the normal route through the
body's neuromuscular system from the brain to the finger on a mouse. By reading signals from
an array of neurons and using computer chips and programs to translate the signals into action,
BCI can enable a person suffering from paralysis to write a book or control a motorized
wheelchair or prosthetic limb through thought aloneMany physiological disorders such as
Amyotrophic Lateral Sclerosis (ALS) or injuries such as high-level spinal cord injury can disrupt
the communication path between the brain and the body. This is where brain computer interface
comes into play contributing for beneficial real time services and applications.
1.1The Wonder Machine – Human Brain:
The reason a BCI works at all is because of the way our brains function. Our brains are
filled with neurons, individual nerve cells connected to one another by dendrites and axons.
Every time we think, move, feel or remember something, our neurons are at work.That work is
carried out by small electric signals that zip from neuron to neuron as fast as 250 mph. The
signals are generated by differences in electric potential carried by ions on the membrane of each
neuron. Although the paths the signals take are insulated by something called myelin, some of
the electric signal escapes. Scientists can detect those signals, interpret what they mean and use
them to direct a device of some kind. It can also work the other way around. For example,
researchers could figure out what signals are sent to the brain by the optic nerve when someone
sees the color red. They could rig a camera that would send those exact signals into someone's
brain whenever the camera saw red, allowing a blind person to "see" without eyes.
3. Department of ECE
3
SVS Institute of Technology
1.2Cortical Plasticity:
The brain actually remains flexible even into old age. This concept, known
ascorticalplasticity.The brain is able to adaptin amazing ways to new circumstances. Learning
something new or partaking in novel activities forms new connections between neurons and
reduces the onset of age-related neurological problems. If an adult suffers a brain injury, other
parts of the brain are able to take over the functions of the damaged portion.
1.3The target of BCI system:
The potential users of BCI systems include
1. Individuals who are truly unlocked.
2. Individuals who have a very limited capacity for control, e.g., useful eye movement.
3. Individuals who retain substantial neuromuscular control.
Currently, the second class is the main target of BCI communication and applications.
This is because BCI systems are designed for individuals with motor disabilities to communicate
with the outside world. The number of control options that BCI systems currently provide is also
very limited at the time being. So only an individual who really needs to use a BCI system (and
does not have any other useful communication channel) may be willing to use a BCI system in
the long run.
4. Department of ECE
4
SVS Institute of Technology
2. WORKING ARCHITECTURE
2.1 Model of Brain Computer Interface:
Fig 2.1 BCI Model Diagram
Before moving to real implications of BCI and its application let us first discuss the three
types of BCI. These types are decided on the basis of the technique used for the interface. Each
of these techniques has some advantages as well as some disadvantages. The three types of BCI
are as follows with their features
2.2Types of BCI:
2.2.1Invasive BCIs:
Invasive BCI are directly implanted into the grey matter of the brain during
neurosurgery. They produce the highest quality signals of BCI devices. Invasive BCIs has
targeted repairing damaged sight and providing new functionality to paralyzed people.
But these BCIs are prone to building up of scar-tissue which causes the signal to become
weaker and even lost as body reacts to a foreign object in the brain.
5. Department of ECE
5
SVS Institute of Technology
Fig.2.2 Jens Naumann, a man with acquired blindness, being interviewed about his
vision BCI on CBS's the Early Show
In vision science, direct brain implants have been used to treat non- congenital i.e.
acquired blindness.Oneofthefirst scientists to come up with a working brain interface to
restore sight as private researcher, William Dobelle.
Dobelle‟s first prototype was implanted into Jerry, a man blinded in adulthood,
in1978. A single-array BCI containing 68 electrodes was implanted ontoJerry‟s visual
cortex and succeeded in producing phosphenes, the sensation of seeing light. The system
included TV cameras mounted on glasses to send signals to the implant. Initially the
implant allowed Jerry to see shades of grey in a limited field of vision and at a low frame-
rate also requiring him to be hooked up to a two-ton mainframe. Shrinking electronics
and faster computers made his artificial eye more portable and allowed him to perform
simple tasks unassisted.
In 2002, Jens Naumann, also blinded in adulthood, became the first in a series of
16 paying patients to receive Dobelle‟s second generation implant, marking one of the
earliest commercial uses of BCIs. The second generation device used a more
sophisticated implant enabling better mapping of phosphenes into coherent vision.
Phosphenes are spread out across the visual field in what researchers call the starry-night
effect. Immediately after his implant, Jens was able to use imperfectly restored vision to
drive slowly around the parking area of the research institute.
BCIs focusing on motor Neuroprosthetics aim to either restore movement in
paralyzed individuals or provide devices to assist them, such as interfaces with computers
or robot arms. Researchers at Emory University in Atlanta led by Philip Kennedy and
Roy Bakay were first to install a brain implant in a human that produced signals of high
enough quality to stimulate movement. Their patient, Johnny Ray, suffered from „locked-
6. Department of ECE
6
SVS Institute of Technology
in syndrome‟ after suffering a brain-stem stroke. Ray‟s implant was installed in 1998 and
he lived long enough to start working with the implant, eventually learning to control a
computer cursor.
Tetraplegic Matt Nagle became the first person to control an artificial hand using a
BCI in 2005 as part of the nine-month human trail of cyber kinetics
Neurotechnology‟sBraingate chip-implant. Implanted in Nagle‟s right
precentralgyrus(area of the motor cortex for arm movement), the 96 electrode Braingate
implant allowed Nagle to control a robotic arm by thinking about moving his hand as
well as a computer cursor, lights and TV.
2.2.2 Partially Invasive BCI:
Partially invasive BCI devices are implanted inside the skull but rest outside the
brain rather than amidst the grey matter. They produce better resolution signals than non-
invasive BCIs where the bone tissue of the cranium deflects and deforms signals and
have a lower risk of forming scar-tissue in the brain than fully- invasive BCIs.
Electrocorticography (ECoG) uses the same technology as non-invasive
electroencephalography, but the electrodes are embedded in a thin plastic pad that is
placed above the cortex, beneath the dura mater. ECoG technologies were first traled in
humans in 2004 by Eric Leuthardt and Daniel Moran from Washington University in St
Louis. In a later trial, the researchers enabled a teenage boy to play Space Invaders using
his ECoG implant. This research indicates that it is difficult to produce kinematic BCI
devices with more than one dimension of control using ECoG.
Light Reactive Imaging BCI devices are still in the realm of theory. These would
involve implanting laser inside the skull. The laser would be trained on a single neuron
and the neuron‟s reflectance measured by a separate sensor. When neuron fires, the laser
light pattern and wavelengths it reflects would change slightly. This would allow
researchers to monitor single neurons but require less contact with tissue and reduce the
risk of scar-tissue build up.
2.2.3 Non-Invasive BCI:
As well as invasive experiments, there have also been experiments in humans
using non-invasive neuroimaging technologies as interfaces. Signals recorded in this way
have been used to power muscle implants and restore partial movement in an
experimental volunteer. Although they are easy to wear, non- invasive implants produce
poor signal resolution because the skull dampens signals, dispersing and blurring the
7. Department of ECE
7
SVS Institute of Technology
electromagnetic waves created by the neurons. Although the waves can still be detected it
is more difficult to determine the area of the brain that created them or the actions of
individual neurons.
Fig.2.3: Recordings of brainwaves produced by an electroencephalogram
Electroencephalography (EEG) is the most studied potential non-invasive
interface, mainly due to its fine temporal resolutions, ease of use, portability and low set-
up cost. But as well as the technology's susceptibility to noise, another substantial barrier
to using EEG as a brain-computer interface is the extensive training required before users
can work the technology. For example, in experiments beginning in the mid-1990s,
NielsBirbaumer of the University of Tubingen in Germany used EEG recordings of slow
cortical potential to give paralysed patients limited control over a computer
cursor.(Birbaumer had earlier trained epileptics to prevent impending fits by controlling
this low voltage wave.) The experiment saw ten patients trained to move a computer
cursor by controlling their brainwaves. The process was slow, requiring more than an
hour for patients to write 100 characters with the cursor, while training often took many
months.
Another research parameter is the type of waves measured. Birbaumer's later
research with Jonathan Wolpaw at New York State University has focused on developing
technology that would allow users to choose the brain signals they found easiest to
operate a BCI, including mu and beta waves. A further parameter is the method of
feedback used and this is shown in studies of P300 signals. Patterns of P300 waves are
generated involuntarily (stimulus- feedback) when people see something they recognise
and may allow BCIs to decode categories of thoughts without training patients first. By
contrast, the biofeedback methods described above require learning to control brainwaves
so the resulting brain activity can be detected. In 2000, for example, research by Jessica
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Bayliss at the University of Rochester showed that volunteers wearing virtual reality
helmets could control elements in a virtual world using their P300 EEG readings,
including turning lights on and off and bringing a mock-up car to a stop. In 1999,
researchers at Case Western Reserve University led by Hunter Peckham, used 64-
electrode EEG skullcap to return limited hand movements to quadriplegic Jim Jatich. As
Jatich concentrated on simple but opposite concepts like up and down, his beta-rhythm
EEG output was analysed using software to identify patterns in the noise. A basic pattern
was identified and used to control a switch: Above average activity was set to on, below
average off. As well as enabling Jatich to control a computer cursor the signals were also
used to drive the nerve controllers embedded in his hands, restoring some movement.
Electronic neural-networks have been deployed which shift the learning phase from the
user to the computer. Experiments by scientists at the Fraunhofer Society in 2004 using
neural networks led to noticeable improvements within 30 minutes of training.
Experiments by Edurado Miranda aim to use EEG recordings of mental activity
associated with music to allow the disabled to express themselves musically through an
encephalophone. Magnetoencephalography (MEG) and functional magnetic resonance
imaging (fMRI) have both been used successfully as non-invasive BCIs. In a widely
reported experiment, fMRI allowed two users being scanned to play Pong in real-time by
altering their haemodynamic response or brain blood flow through biofeedback
techniques. fMRI measurements of haemodynamic responses in real time have also been
used to control robot arms with a seven second delay between thought and movement.
2.3 Animal BCI research:
Fig.2.4: Rats implanted with BCIs in Theodore Berger's experiments
Several laboratories have managed to record signals from monkey and rat cerebral
cortexes in order to operate BCIs to carry out movement. Monkeys have navigated computer
cursors on screen and commanded robotic arms to perform simple tasks simply by thinking about
the task and without any motor output. Other research on cats has decoded visual signals.
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2.3.1 Early work:
Studies that developed algorithms to reconstruct movements from motor cortex
neurons, which control movement, date back to the 1970s. Work by groups led by
Schmidt, Fetz and Baker in the 1970s established that monkeys could quickly learn to
voluntarily control the firing rate of individual neurons in the primary motor cortex after
closed-loop operant conditioning, a training method using punishment and rewards.
In the 1980s, ApostolosGeorgopoulos at Johns Hopkins University found a
mathematical relationship between the electrical responses of single motor-cortex
neurons in rhesus macaque monkeys and the direction that monkeys moved their arms
(based on a cosine function). He also found that dispersed groups of neurons in different
areas of the brain collectively controlled motor commands but was only able to record the
firings of neurons in one area at a time because of technical limitations imposed by his
equipment.
There has been rapid development in BCIs since the mid-1990s. Several groups
have been able to capture complex brain motor centre signals using recordings from
neural ensembles (groups of neurons) and use these to control external devices, including
research groups led by Richard Andersen, John Donoghue, Phillip Kennedy, Miguel
Nicolelis, and Andrew Schwartz.
2.3.2 Prominent research successes:
Phillip Kennedy and colleagues built the first intra-cortical brain-computer
interface by implanting neurotrophic-cone electrodes into monkeys.
fig.2.5: Garrett Stanley's recordings of cat vision using a BCI implanted in the
lateral geniculation nucleus (top row: original image; bottom row: recording)
In 1999, researchers led by Garrett Stanley at Harvard University decoded
neuronal firings to reproduce images seen by cats. The team used an array of electrodes
embedded in the thalamus (which integrates all of the brain‟s sensory input) of sharp-
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eyed cats. Researchers targeted 177 brain cells in the thalamus lateral geniculate nucleus
area, which decodes signals from the retina. The cats were shown eight short movies, and
their neuron firings were recorded. Using mathematical filters, the researchers decoded
the signals to generate movies of what the cats saw and were able to reconstruct
recognizable scenes and moving objects.
Miguel Nicolelis has been a prominent proponent of using multiple electrodes
spread over a greater area of the brain to obtain neuronal signals to drive a BCI. Such
neural ensembles are said to reduce the variability in output produced by single
electrodes, which could make it difficult to operate a BCI.
After conducting initial studies in rats during the 1990s, Nicolelis and his
colleagues developed BCIs that decoded brain activity in owl monkeys and used the
devices to reproduce monkey movements in robotic arms. Monkeys have advanced
reaching and grasping abilities and good hand manipulation skills, making them ideal test
subjects for this kind of work.
By 2000, the group succeeded in building a BCI that reproduced owl monkey
movements while the monkey operated a joystick or reached for food.The BCI operated
in real time and could also control a separate robot remotely over Internet protocol. But
the monkeys could not see the arm moving and did not receive any feedback, a so-called
open-loop BCI.
fig.2.6: Diagram of the BCI developed by Miguel Nicolelis and collegues for use on Rhesus
monkeys.
Later experiments by Nicolelis using rhesus monkeys, succeeded in closing the
feedback loop and reproduced monkey reaching and grasping movements in a robot arm.
With their deeply cleft and furrowed brains, rhesus monkeys are considered to be better
models for human neurophysiology than owl monkeys. The monkeys were trained to
reach and grasp objects on a computer screen by manipulating a joystick while
corresponding movements by a robot arm were hidden. The monkeys were later shown
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the robot directly and learned to control it by viewing its movements. The BCI used
velocity predictions to control reaching movements and simultaneously predicted hand
gripping force.
Other labs that develop BCIs and algorithms that decode neuron signals include
John Donoghue from Brown University, Andrew Schwartz from the University of
Pittsburgh and Richard Andersen from Caltech. These researchers were able to produce
working BCIs even though they recorded signals from far fewer neurons than Nicolelis
(15–30 neurons versus 50–200 neurons).
Donoghue's group reported training rhesus monkeys to use a BCI to track visual
targets on a computer screen with or without assistance of a joystick (closed-loop
BCI).Schwartz's group created a BCI for three-dimensional tracking in virtual reality and
also reproduced BCI control in a robotic arm. The group created headlines when they
demonstrated that a monkey could feed itself pieces of zucchini using a robotic arm
powered by the animal's own brain signals.
Andersen's group used recordings of pre-movement activity from the posterior
parietal cortex in their BCI, including signals created when experimental animals
anticipated receiving a reward.
In addition to predicting kinematic and kinetic parameters of limb movements,
BCIs that predict electromyography or electrical activity of muscles are being
developed.Such BCIs could be used to restore mobility in paralyses limbs by electrically
stimulating muscles.
2.4Cell-culture BCIs:
Researchers have also built devices to interface with neural cells and entire neural
networks in cultures outside animals. As well as furthering research on animal implantable
devices, experiments on cultured neural tissue have focused on building problem-solving
networks, constructing basic computers and manipulating robotic devices. Research into
techniques for stimulating and recording from individual neurons grown on semiconductor chips
is sometimes referred to as neuroelectronics or neurochips.
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Fig.2.7: World firstNeurochip developed by Caltech researchers Jerome Pine and Michael
Maher
Development of the first working neurochip was claimed by a Caltech team led by
Jerome Pine and Michael Maher in 1997. The Caltech chip had room for 16 neurons.
In 2003, a team led by Theodore Berger at the University of Southern California started
work on a neurochip designed to function as an artificial or prosthetic hippocampus. The
neurochip was designed to function in rat brains and is intended as a prototype for the eventual
development of higher-brain prosthesis. The hippocampus was chosen because it is thought to be
the most ordered and structured part of the brain and is the most studied area. Its function is to
encode experiences for storage as long-term memories elsewhere in the brain.
Thomas DeMarse at the University of Florida used a culture of 25,000 neurons taken
from a rat's brain to fly a F-22 fighter jet aircraft simulator.After collection, the cortical neurons
were cultured in a petri dish and rapidly begin to reconnect themselves to form a living neural
network. The cells were arranged over a grid of 60 electrodes and trained to control the pitch and
yaw functions of the simulator. The study's focus was on understanding how the human brain
performs and learns computational tasks at a cellular level.
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3. BRAIN GATE
3.1 Brain gate interface model:
fig.3.1: Dummy unit illustrating the design of a Brain Gate interface
Brain Gate is a brain implant system developed by the bio-tech company Cyberkietics in
2003 in conjunction with the Department of Neuroscience at Brown University. The device was
designed to help those who have lost control of their limbs, or other bodily functions, such as
patients with amyotrophic lateral sclerosis (ALS) or spinal cord injury. The computer chip,
which is implanted into the brain, monitors brain activity in the patient and converts the intention
of the user into computer commands.
Currently the chip uses 100 hair-thin electrodes that sense the electro- magnetic signature
of neurons firing in specific areas of the brain, for example, the area that controls arm movement.
The activity is translated into electrically charged signals and is then sent and decoded using a
program, which can move either a robotic arm or a computer cursor. According to the Cyber
kinetics' website, three patients have been implanted with the BrainGate system. The company
has confirmed that one patient (Matt Nagle) has a spinal cord injury, whilst another has advanced
ALS.
In addition to real-time analysis of neuron patterns to relay movement, the Braingate
array is also capable of recording electrical data for later analysis. A potential use of this feature
would be for a neurologist to study seizure patterns in a patient with epilepsy.
Cyber kinetics has a vision, CEO Tim Surgenor explained to Gizmag, but it is not
promising "miracle cures", or that quadriplegic people will be able to walk again - yet. Their
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primary goal is to help restore many activities of daily living that are impossible for paralyzed
people and to provide a platform for the development of a wide range of other assistive devices.
"Today quadriplegic people are satisfied if they get a rudimentary connection to the
outside world. What we're trying to give them is a connection that is as good and fast as using
their hands. We're going to teach them to think about moving the cursor using the part of the
brain that usually controls the arms to push keys and create, if you will, a mental device that can
input information into a computer. That is the first application, a kind of prosthetic, if you will.
Then it is possible to use the computer to control a robot arm or their own arm, but that would be
down the road."
Existing technology stimulates muscle groups that can make an arm move. The problem
Surgenor and his team faced were in creating an input or control signal. With the right control
signal they found they could stimulate the right muscle groups to make arm movement.
"Another application would be for somebody to handle a tricycle or exercise machine to help
patients who have a lot of trouble with their skeletal muscles. But walking, I have to say, would
be very complex. There are a lot of issues with balance and that's not going to be an easy thing to
do, but it is a goal."
Cyber kinetics hopes to refine the Brain Gate in the next two years to develop a wireless
device that is completely implantable and doesn't have a plug,making it safer and less visible.
And once the basics of brain mapping are worked out there is potential for a wide variety of
further applications, Surgenor explains.
"If you could detect or predict the onset of epilepsy, which would be a huge therapeutic
application for people who have seizures, which leads to the idea of a 'pacemaker for the brain'.
So eventually people may have this technology in their brains and if something starts to go
wrong it will take a therapeutic action. That could be available by 2007 to 2008."
"If we can figure out how to make this device cheaper, there might be applications for
people to control machines, write software or perform intensive actions. But that's a good
distance away. Right now the only way to get that level of detail from these signals is to actually
have surgery to place this on the surface of the brain. It's not possible to do this with a non-
invasive approach. For example, you can have an EEG and if you concentrate really hard you
can think about and move a cursor on a screen, but if someone makes a loud noise or you get
interrupted, you lose that ability. What we're trying to make here is a direct connection. The
[BrainGate] is going to be right there and you won't have to think about it."
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3.2 DARPA:
The Brown University group was partially funded by the Defence Advanced Research
Projects Agency (DARPA), the central research and development organisation for the US
Department of Defence (DoD). DARPA has been interested in Brain-Machine- Interfaces (BMI)
for a number of years for military applications like wiring fighter pilots directly to their planes to
allow autonomous flight from the safety of the ground. Future developments are also envisaged
in which humans could 'download' memory implants for skill enhancement, allowing actions to
be performed that have not been learned directly.
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4. BCI APPLICATIONS
After we go through the various techniques of BCI the first question that comes to our
mind is, what does BCI do to us and what are its applications.So BCI in today‟s time turns useful
to us in many ways. Whether it may be any medical field or a field leading to enhancement of
human environment.
Communication
Yes/no communication
Speller
Web browser
Mobility
Wheel chair control
Robotics
BCI for recreation
Games
Virtual reality
Creative expressions
Music
Visual art
BCIs for Cognitive Diagnostics and Augmented Cognition
Coma detection
Meditation training
Some of the BCI applications are discussed below:
4.1 The Mental Typewriter:
March 14, 2006 Scientists demonstrated a brain-computer interface that translates brain
signals into computer control signals this week at CeBIT in Berlin. The initial project
demonstrates how a paralyses patient could communicate by using a mental typewriter alone –
without touching the keyboard. In the case of serious accident or illness, a patient‟s limbs can be
paralyzed, severely restricting communication with the outside world.
The interface is already showing how it can help these patients to write texts and thus
communicate with their environment. There‟s also a PONG game (computer tennis) used to
demonstrate how the interface can be used. Brain Pong involves two BBCI users playing a game
of teletennis in which the “rackets” are controlled by imagining movements and predictably the
general media has focused the majority of its attention on computer gaming applications but
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BCCI could equally be used in safety technologies, in controlling prostheses, wheelchairs,
instruments and even machinery.
On the first day of the 2006 CeBIT Computer Fair, Fraunhofer FIRST and the Berlin
Charité demonstrated how the mental typewriter could be used for this purpose. On the other
days of the CeBIT Fair, a simulated test setup using a shop-window dummy will be on display.
Cooperation between Fraunhofer FIRST and the Charité to develop an interface between
the human brain and the computer began some years ago. The result was the Berlin Brain-
Computer Interface (BBCI) which uses the electrical activity of the brain in the form of an
electroencephalogram (EEG). Electrodes attached to the scalp measure the brain‟s electrical
signals. These are then amplified and transmitted to the computer, which converts them into
technical control signals. The principle behind the BBCI is that the activity of the brain already
reflects the purely mental conception of a particular behaviour, e.g. the idea of moving a hand or
foot.The BBCI recognizes the corresponding changes in brain activity and uses them, say, to
choose between two alternatives: one involves imagining that the left hand is moved, the other
that the right hand is moved. This enables a cursor, for example, to be moved to the left or right.
The person operating the mental typewriter uses the cursor to select a letters field. The next step
reduces the choice, and after a few more steps we arrive at the individual letters, which can be
used to write words. This process enables simple sentences to be constructed within minutes.
A first prototype of the mental typewriter is currently available. In a series of
experiments, different spelling methods are tested in terms of their usability and are adapted to
the BBCI. It will be some years, though, before the mental typewriter can be used in everyday
applications. Further research is needed, in particular to refine the EEG sensors.
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4.2 BCI for disable people:
Fig 4.1 BCI working model for Disable people
One of the most exciting areas of BCI research is the development of devices that can be
controlled by thoughts. Some of the applications of this technology may seem frivolous, such as
the ability to control a video game by thought. If you think a remote control is convenient,
imagine changing channels with your mind.
However, there's a bigger picture -- devices that would allow severely disabled people to
function independently. For a quadriplegic, something as basic as controlling a computer cursor
via mental commands would represent a revolutionary improvement in quality of life. But how
do we turn those tiny voltage measurements into the movement of a robotic arm?
Early research used monkeys with implanted electrodes. The monkeys used a joystick to
control a robotic arm. Scientists measured the signals coming from the electrodes. Eventually,
they changed the controls so that the robotic arm was being controlled only by the signals
coming from the electrodes, not the joystick.
A more difficult task is interpreting the brain signals for movement in someone who can't
physically move their own arm. With a task like that, the subject must "train" to use the device.
With an EEG or implant in place, the subject would visualize closing his or her right hand. After
many trials, the software can learn the signals associated with the thought of hand-closing.
Software connected to a robotic hand is programmed to receive the "close hand" signal and
interpret it to mean that the robotic hand should close. At that point, when the subject thinks
about closing the hand, the signals are sent and the robotic hand closes.
A similar method is used to manipulate a computer cursor, with the subject thinking
about forward, left, right and back movements of the cursor. With enough practice, users can
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gain enough control over a cursor to draw a circle, access computer programs and control a TV.
It could theoretically be expanded to allow users to "type" with their thoughts.
Once the basic mechanism of converting thoughts to computerized or robotic action is
perfected, the potential uses for the technology are almost limitless. Instead of a robotic hand,
disabled users could have robotic braces attached to their own limbs, allowing them to move and
directly interact with the environment. This could even be accomplished without the "robotic"
part of the device. Signals could be sent to the appropriate motor control nerves in the hands,
bypassing a damaged section of the spinal cord and allowing actual movement of the subject's
own hands
4.3 Adaptive BCI for Augmented Cognition and Action:
The goal of this project is to demonstrate improved human/computer performance for
specific tasks through detection of task-relevant cognitive events with real-time EEG. For
example, in tasks for which there is a direct tradeoff between reaction time and error rate, (such
as typing or visual search) it may be beneficial to correct a user‟s errors without interrupting the
pace of the primary task. Such a user interface is possible through the direct detection of EEG
signatures associated with the perception of a error, often referred to as Error Related Negativity.
In general such signatures may be used to dynamically adjust the behavior of human- computer
interfaces and information displays.
This project advances signal analysis techniques for high density EEG to detect discrete
events associated with cognitive processing. Corresponding real- time adaptive interfaces with
sub-second latency are being designed to evaluate this concept of an adaptive brain-computer
interface in three specific applications:
4.3.1 Error and conflict perception:
Error related negativity (ERN) in EEG has been linked to perceived response
errors and conflicts in decision-making. In this project we have developed single trial
ERN detection to predict task-related errors. The system can be used as an automated
real-time decision checker for time-sensitive control tasks. In the first phase of this
project we demonstrated improved human/computer performance at a rapid forced choice
discrimination task with an average 23% reduction of human errors. This open-loop error
correction paradigm represents the first application of real-time cognitive event detection
and demonstrates the utility of real-time EEG brain monitoring within the Augmented
Cognition program. We will evaluate video game scenarios with closed-loop feedback at
latencies of less than 150 ms where detected errors are corrected or application
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parameters such as speed are varied according to the measured or "gauged" conflict
perception.
4.3.2 Working memory encoding:
Transient modulation of oscillations in the theta (4-8 Hz) and gamma (20-30 Hz)
bands, recorded using EEG and magneto encephalography (MEG), have been implicated
in the encoding and retrieval of semantic information in working memory. In this project
we will exploit these neural correlates of semantic processing to detect problems with
semantic information processing. This memory gauge could be used to detect memory
recall deficits, and repeat or enhance the presented information and thus better prime
memory recall.
4.4 Bio-feedback system:
The particular person who wants to work on this system should undergo a training
programmed using bio-feedback system. The electrical activity of the human brain was recorded
by the implant electrode, and it supplies required signals for the system to work accordingly.
Thus the person gradually learns which thought make the computer to work faster andfaster.
Likewise, the method of operating is practiced for various actions and to do various executions.
Thus, the particular person becomes entrepreneur in operating and controlling computers through
this magical power, Brain Computer Interface.
Fig 4.2 Bio-feedback system.
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4.5Drawbacks in using BCI system:
The brain is incredibly complex. To say that all thoughts or actions are the result of simple
electric signals in the brain is a gross understatement. There are about 100 billion neurons in a
human brain .Each neuron is constantly sending and receiving signals through a complex web of
connections. There are chemical processes involved as well, which EEGs can't pick up on.
The signal is weak and prone to interference. EEGs measure tiny voltage potentials. Something as
simple as the blinking eyelids of the subject can generate much stronger signals. Refinements in
EEGs and implants will probably overcome this problem to some extent in the future, but for
now, reading brain signals is like listening to a bad phone connection. There's lots of static.
The equipment is less than portable. It's far better than it used to be -- early systems were
hardwired to massive mainframe computers. But some BCI‟s still require a wired connection to
the equipment, and those that are wireless require the subject to carry a computer that can weigh
around 10 pounds. Like all technology, this will surely become lighter and more wireless in the
future.
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5. CONCLUSION
Brain-Computer Interface (BCI) is a method of communication based on voluntary neural
activity generated by the brain and independent of its normal output pathways of peripheral
nerves and muscles.
The neural activity used in BCI can be recorded using invasive or noninvasive
techniques.We can say as detection techniques and experimental designs improve, the BCI will
improve as well and would provide wealth alternatives for individuals to interact with their
environment.
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6. REFERENCES
www. eelinks.net
www. techon.nikkeibp.co.jp
http://www.nicolelislab.net/NLnet_Load.html
http://www.youtube.com/watch?v=7-cpcoIJbOU
http://www.en.wikipedia.com/braincomputerinterface
www.cnn.com
www.wired.com
www.howstuffworks.com
Sixto Ortiz Jr., "Brain-Computer Interfaces: Where Human and Machine Meet,"
Computer, vol. 40, no. 1, pp. 17-21, Jan., 2007
F. Babiloni, A. Cichocki, and S. Gao, eds., special issue, “Brain-Computer Interfaces:
Towards Practical Implementations and Potential Applications,”
ComputationalIntelligence and Neuroscience, 2007
P. Sajda, K-R. Mueller, and K.V. Shenoy, eds., special issue, “Brain Computer
Interfaces,” IEEE Signal Processing Magazine,Jan. 2008
The MIT Press – “Toward Brain-Computer Interfacing”