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The Role of Interventional 
Radiology in Management of 
Pleural Effusion, Empyema and 
Lung Abscess 
Prof. Abdulsalam Y Taha 
School of Medicine 
University of Sulaimani 
Iraq 
https://sulaimaniu.academia.edu/AbdulsalamTaha 
10/15/2014 Prof. Abdulsalam Y Taha 1
Reference 
10/15/2014 Prof. Abdulsalam Y Taha 2
Abstract 
10/15/2014 Prof. Abdulsalam Y Taha 3
Pleural Effusion 
• The pleural space normally contains 5-10 mL of serous 
fluid, which is secreted mainly from the parietal 
pleura at a rate of 0.01 mL/kg/hr and absorbed 
through lymphatics in the parietal pleura. 
• In certain clinical conditions, the balance between 
secretion and absorption can be disturbed and the 
fluid starts accumulating in the pleural space. 
• Pleural effusion is defined as an abnormal collection 
of fluid in the pleural space. 
• Incidence: approximately 1.5 million people are 
diagnosed with pleural effusion each year in USA. 
10/15/2014 Prof. Abdulsalam Y Taha 4
Types of PE 
• Transudate is due to increased hydrostatic or 
decreased oncotic pressure while the capillary 
beds of pleural membranes are intact. 
• Common causes of transudate are congestive HF 
and liver cirrhosis. 
• An exudate is due to leak of fluid due to 
increased capillary permeability of the diseased 
capillary bed. 
• Common causes of an exudative PE are 
pneumonia, malignancy, pulmonary embolism 
and GI diseases. 
10/15/2014 Prof. Abdulsalam Y Taha 5
10/15/2014 Prof. Abdulsalam Y Taha 6
Other forms of PF 
• Para-pneumonic PE is the commonest cause 
of exudative PE; it results from bacterial 
pneumonia, lung abscess or bronchiectasis. 
• It usually resolves by appropriate medical 
treatment. However, it may get infected and 
progress into empyema. 
10/15/2014 Prof. Abdulsalam Y Taha 7
Clinical Features of PE 
10/15/2014 Prof. Abdulsalam Y Taha 8
Diagnostic Tools 
• Plain chest radiography: ( this is the initial 
tool, ˃ 175 mL in PA view is needed for 
detection, 10 mL in lateral decubitus view). 
• Ultra-sonography: for detection of small PE 
and guidance of thoracentesis and 
percutaneous pleural drainage catheters. 
• Computed tomography – CT: 
a. For localization of skin entry site. 
b. The image study of choice for evaluation of 
pleural pathology and underlying lung 
disease. 
10/15/2014 Prof. Abdulsalam Y Taha 9
Treatment options for PE 
• Uncomplicated (transudate) PE can be managed 
by conservative treatment or antibiotics alone. 
• Complicated PE ( large loculated PE, exudate, 
malignant PE, empyema and hemothorax) need 
drainage. 
• The goal of treatment is to palliate the 
symptoms, expand and treat the underlying 
lung. 
• The treatment options include: theraputic 
thoracentesis, drainage catheter placement, 
fibrinolytic therapy, pleurodesis and surgery. 
10/15/2014 Prof. Abdulsalam Y Taha 10
Thoracentesis 
• To differentiate a transudate from an exudate 
and to relieve symptoms. 
• Fifty mL of fluid are usually required for 
diagnostic thoracentesis. 
• The most common indication for diagnostic 
thoracentesis is a fluid in the pleural space more 
than 10 mL in thickness on lateral decubitus 
chest radiograph with unknown etiology. 
• If the patient has a shortness of breath at rest, 
up to 1500 mL of fluid should be removed to 
relieve the symptom. 
10/15/2014 Prof. Abdulsalam Y Taha 11
10/15/2014 Prof. Abdulsalam Y Taha 12
Thoracentesis Procedure 
• A bed side procedure. 
• Can be performed with or without US guidance. 
• In order to avoid complications, US is generally recommended for 
small or loculated PE or in patients receiving positive-pressure 
ventilation. 
• US saves time and improves the first-puncture success of 
thoracentesis. 
• Contineous US guidance is essential for a safe thoracentesis with 
a high success rate. 
• Complications: pneumothorax (2-6%), half need a chest tube, 
hemothorax (1%), re-expansion pulmonary oedema and organ 
laceration (both are rare). 
• Though CXR is usually performed immediately after thoracentesis 
to exclude pneumothorax, one study showed that it has a limited 
role in the evaluation of complications. Therefore, it is generally 
not recommended unless there is a clinical suspision. 
10/15/2014 Prof. Abdulsalam Y Taha 13
Empyema 
10/15/2014 Prof. Abdulsalam Y Taha 14
10/15/2014 Prof. Abdulsalam Y Taha 15
10/15/2014 Prof. Abdulsalam Y Taha 16
10/15/2014 Prof. Abdulsalam Y Taha 17
10/15/2014 Prof. Abdulsalam Y Taha 18
10/15/2014 Prof. Abdulsalam Y Taha 19
10/15/2014 Prof. Abdulsalam Y Taha 20
10/15/2014 Prof. Abdulsalam Y Taha 21
Other Topics (to be continued) 
• Non-tunneled pigtail drainage catheter 
placement. 
• Tunneled drainage catheter placement. 
• Intra-pleural fibrinolytic therapy. 
• Pleurodesis. 
• Lung abscess. 
10/15/2014 Prof. Abdulsalam Y Taha 22

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The role of interventional radiology in management of Plural effusion, empyema and lung abscess

  • 1. The Role of Interventional Radiology in Management of Pleural Effusion, Empyema and Lung Abscess Prof. Abdulsalam Y Taha School of Medicine University of Sulaimani Iraq https://sulaimaniu.academia.edu/AbdulsalamTaha 10/15/2014 Prof. Abdulsalam Y Taha 1
  • 2. Reference 10/15/2014 Prof. Abdulsalam Y Taha 2
  • 3. Abstract 10/15/2014 Prof. Abdulsalam Y Taha 3
  • 4. Pleural Effusion • The pleural space normally contains 5-10 mL of serous fluid, which is secreted mainly from the parietal pleura at a rate of 0.01 mL/kg/hr and absorbed through lymphatics in the parietal pleura. • In certain clinical conditions, the balance between secretion and absorption can be disturbed and the fluid starts accumulating in the pleural space. • Pleural effusion is defined as an abnormal collection of fluid in the pleural space. • Incidence: approximately 1.5 million people are diagnosed with pleural effusion each year in USA. 10/15/2014 Prof. Abdulsalam Y Taha 4
  • 5. Types of PE • Transudate is due to increased hydrostatic or decreased oncotic pressure while the capillary beds of pleural membranes are intact. • Common causes of transudate are congestive HF and liver cirrhosis. • An exudate is due to leak of fluid due to increased capillary permeability of the diseased capillary bed. • Common causes of an exudative PE are pneumonia, malignancy, pulmonary embolism and GI diseases. 10/15/2014 Prof. Abdulsalam Y Taha 5
  • 7. Other forms of PF • Para-pneumonic PE is the commonest cause of exudative PE; it results from bacterial pneumonia, lung abscess or bronchiectasis. • It usually resolves by appropriate medical treatment. However, it may get infected and progress into empyema. 10/15/2014 Prof. Abdulsalam Y Taha 7
  • 8. Clinical Features of PE 10/15/2014 Prof. Abdulsalam Y Taha 8
  • 9. Diagnostic Tools • Plain chest radiography: ( this is the initial tool, ˃ 175 mL in PA view is needed for detection, 10 mL in lateral decubitus view). • Ultra-sonography: for detection of small PE and guidance of thoracentesis and percutaneous pleural drainage catheters. • Computed tomography – CT: a. For localization of skin entry site. b. The image study of choice for evaluation of pleural pathology and underlying lung disease. 10/15/2014 Prof. Abdulsalam Y Taha 9
  • 10. Treatment options for PE • Uncomplicated (transudate) PE can be managed by conservative treatment or antibiotics alone. • Complicated PE ( large loculated PE, exudate, malignant PE, empyema and hemothorax) need drainage. • The goal of treatment is to palliate the symptoms, expand and treat the underlying lung. • The treatment options include: theraputic thoracentesis, drainage catheter placement, fibrinolytic therapy, pleurodesis and surgery. 10/15/2014 Prof. Abdulsalam Y Taha 10
  • 11. Thoracentesis • To differentiate a transudate from an exudate and to relieve symptoms. • Fifty mL of fluid are usually required for diagnostic thoracentesis. • The most common indication for diagnostic thoracentesis is a fluid in the pleural space more than 10 mL in thickness on lateral decubitus chest radiograph with unknown etiology. • If the patient has a shortness of breath at rest, up to 1500 mL of fluid should be removed to relieve the symptom. 10/15/2014 Prof. Abdulsalam Y Taha 11
  • 13. Thoracentesis Procedure • A bed side procedure. • Can be performed with or without US guidance. • In order to avoid complications, US is generally recommended for small or loculated PE or in patients receiving positive-pressure ventilation. • US saves time and improves the first-puncture success of thoracentesis. • Contineous US guidance is essential for a safe thoracentesis with a high success rate. • Complications: pneumothorax (2-6%), half need a chest tube, hemothorax (1%), re-expansion pulmonary oedema and organ laceration (both are rare). • Though CXR is usually performed immediately after thoracentesis to exclude pneumothorax, one study showed that it has a limited role in the evaluation of complications. Therefore, it is generally not recommended unless there is a clinical suspision. 10/15/2014 Prof. Abdulsalam Y Taha 13
  • 14. Empyema 10/15/2014 Prof. Abdulsalam Y Taha 14
  • 22. Other Topics (to be continued) • Non-tunneled pigtail drainage catheter placement. • Tunneled drainage catheter placement. • Intra-pleural fibrinolytic therapy. • Pleurodesis. • Lung abscess. 10/15/2014 Prof. Abdulsalam Y Taha 22