Staphylococci

STAPHYLOCOCCI Dr Kamran Afzal Asst Prof Microbiology

Introduction ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object]

Properties ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Staphylococcus aureus ,[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Characteristics

Factors predisposing to S. aureus infections ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Clinical Manifestations ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

A. Due to direct effect of organism ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

B. Toxin mediated diseases ,[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object]

Superantigens ,[object Object],[object Object],[object Object]

Lab Diagnosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Methods ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Gram +ve (purple/blue) cocci Catalase +ve (clusters) Staphylococcus Catalase –ve (chain) streptococcus Coagulase Coagulase +ve S. aureus Coagulase –ve S. epidermidis OR S. saprophyticus S. saprophyticus sensitive S. epidermidis resistant Novobiocin or Colistin (Polymyxin) Catalase test HAEMOLYSIS

Isolation ,[object Object],[object Object],Staphylococcus aureus

Identification ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Test system to identify Staphylococcus

Treatment ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Antibiotic Resistance ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Historical Progression Of Antibiotic Resistance Of S. aureus Antibiotic Year introduced Reports of resistance Penicillin 1941 1940s Streptomycin 1944 mid-1940s Tetracycline 1948 1950s Erythromycin 1952 1950s Methicillin 1959 late 1960s Gentamicin 1964 mid-1970s Ciprofloxacin 1988 late 1980s Vancomycin 1958 1997

Understanding MRSA ,[object Object],[object Object],[object Object]

Problems with MRSA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

MRSA Treatment Options ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Prevention of MRSA Infection ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Staphylococcus epidermidis ,[object Object],[object Object],[object Object],[object Object],[object Object]

Stapylococcus saprophyticus ,[object Object],[object Object],[object Object]

Case History ,[object Object],[object Object]

Staphylococci

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Staphylococci