The Scientific Revolution overturned ideas about the universe that had been accepted since ancient times. Copernicus proposed that the Sun, not the Earth, was at the center of the universe, which was confirmed by Kepler's laws of planetary motion and Galileo's astronomical observations with the telescope. Newton then defined the laws of motion and universal law of gravitation, explaining planetary orbits around the Sun. In medicine, Vesalius, Harvey, and others presented careful observations that disagreed with Galen's anatomical works, while Boyle and Lavoisier contributed to developments in chemistry. The Scientific Method of making systematic observations and using inductive reasoning to form general conclusions was developed.