Metabolism of fat involves catabolic and anabolic processes.
catabolic processes that generate energy.
anabolic processes that create biologically important molecules (cholestrol, triglycerides, phospholipids, and ketone bodies, lipoproteins).
Subject : Nutrition, Unit- VI
This topic provides brief knowledge about lipid metabolism and it is prepared according to INC syllabus for first year BSc Nursing Students.
Digestion and absorption of lipids ppt
what is lipid ppt
digestion of lipid ppt
phase of digestion and absorption ppt
phases of lipids ppt
digestion in mouth and stomach ppt
digestion in small intestine ppt
secretion of lipids ppt
enzyme involved in lipid digestion ppt
transportation phases of lipids ppt
principles of lipid digestion ppt
Lipid metabolism entails the oxidation of fatty acids to either generate energy or synthesize new lipids from smaller constituent molecules. Lipid metabolism is associated with carbohydrate metabolism, as products of glucose (such as acetyl CoA) can be converted into lipids.
Metabolism of fat involves catabolic and anabolic processes.
catabolic processes that generate energy.
anabolic processes that create biologically important molecules (cholestrol, triglycerides, phospholipids, and ketone bodies, lipoproteins).
Subject : Nutrition, Unit- VI
This topic provides brief knowledge about lipid metabolism and it is prepared according to INC syllabus for first year BSc Nursing Students.
Digestion and absorption of lipids ppt
what is lipid ppt
digestion of lipid ppt
phase of digestion and absorption ppt
phases of lipids ppt
digestion in mouth and stomach ppt
digestion in small intestine ppt
secretion of lipids ppt
enzyme involved in lipid digestion ppt
transportation phases of lipids ppt
principles of lipid digestion ppt
Lipid metabolism entails the oxidation of fatty acids to either generate energy or synthesize new lipids from smaller constituent molecules. Lipid metabolism is associated with carbohydrate metabolism, as products of glucose (such as acetyl CoA) can be converted into lipids.
Lipids, classification, digestion and absorptionHu--da
Introduction of lipids
Sources of lipids
Classification of lipids
Trans fat
Alteration of dietary fats during food processing
Digestion, absorption of lipids
Absorption of cholesterol
Lipid transport
Lipid metabolism
Biosynthesis of fatty acids
Essential fatty acids
Oxidation of fatty acids
Impact of diet on fatty acids synthesis
Cholesterol synthesis and excretion
Lipid metabolism is the synthesis and degradation of lipids in cells.
It involves the breakdown or storage of fats for energy and the synthesis of structural and functional lipids, such as those involved in the construction of cell membranes.
In animals, these fats are obtained from food or synthesized by the liver.
Fat usually means any ester of fatty acids or mixture of such compounds most commonly those that occur in living beings or in food. Fat is used as the fatty components of foods and diet. Fats are best known members of a chemical group called the lipids.
Content
Classification
Functions
Sources
Digestion
Absorption
Deficiency and disorders of lipids
Essential fatty acid
Role of omega-3 & omega 6 fatty acids in physiological disorders
References
Are most abundantly distributed organic compounds.
70 kg man= protein weight constitute 12 kg
Skeleton and connective tissue contains half
Body protein and other half is intracellular.
These are major source of energy for living organisms.
Supplying a huge array of metabolic intermediates for biosynthetic reactions.
The structural elements in cell coat or connective tissues.
Lipids, classification, digestion and absorptionHu--da
Introduction of lipids
Sources of lipids
Classification of lipids
Trans fat
Alteration of dietary fats during food processing
Digestion, absorption of lipids
Absorption of cholesterol
Lipid transport
Lipid metabolism
Biosynthesis of fatty acids
Essential fatty acids
Oxidation of fatty acids
Impact of diet on fatty acids synthesis
Cholesterol synthesis and excretion
Lipid metabolism is the synthesis and degradation of lipids in cells.
It involves the breakdown or storage of fats for energy and the synthesis of structural and functional lipids, such as those involved in the construction of cell membranes.
In animals, these fats are obtained from food or synthesized by the liver.
Fat usually means any ester of fatty acids or mixture of such compounds most commonly those that occur in living beings or in food. Fat is used as the fatty components of foods and diet. Fats are best known members of a chemical group called the lipids.
Content
Classification
Functions
Sources
Digestion
Absorption
Deficiency and disorders of lipids
Essential fatty acid
Role of omega-3 & omega 6 fatty acids in physiological disorders
References
Are most abundantly distributed organic compounds.
70 kg man= protein weight constitute 12 kg
Skeleton and connective tissue contains half
Body protein and other half is intracellular.
These are major source of energy for living organisms.
Supplying a huge array of metabolic intermediates for biosynthetic reactions.
The structural elements in cell coat or connective tissues.
Carbohudrate protein and fat metabolism /certified fixed orthodontic courses ...Indian dental academy
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25.1Digestion and Absorption of Lipids
25.2Triacylglycerol Storage and Mobilization
25.3 Glycerol Metabolism
25.4 Oxidation of Fatty Acids
25.5 ATP Production from Fatty Acid Oxidation
25.6 Ketone Bodies
25.7 Biosynthesis of Fatty Acids: Lipogenesis
25.8 Relationship Between Lipogenesis and Citric Acid Cycle Intermediates
25.9 Fate of Fatty-Acid Generated Acetyl CoA
25.10 Relationships Between Lipid and Carbohydrate Metabolism
25.11B Vitamins and Lipid Metabolism
Meat in Human Diet: Balance between nutrition and health
Limitations of prospective cohort studies and epidemiological studies and with respect to less meat affluent countries
Lipid metabolism is the synthesis and degradation of lipids in cells, involving the breakdown and storage of fats for energy and the synthesis of structural and functional lipids, such as those involved in the construction of cell membranes. In animals, these fats are obtained from food and are synthesized by the liver. Lipogenesis is the process of synthesizing these fats. The majority of lipids found in the human body from ingesting food are triglycerides and cholesterol.[4] Other types of lipids found in the body are fatty acids and membrane lipids. Lipid metabolism is often considered as the digestion and absorption process of dietary fat; however, there are two sources of fats that organisms can use to obtain energy: from consumed dietary fats and from stored fat.[5] Vertebrates (including humans) use both sources of fat to produce energy for organs such as the heart to function. Since lipids are hydrophobic molecules, they need to be solubilized before their metabolism can begin. Lipid metabolism often begins with hydrolysis, which occurs with the help of various enzymes in the digestive system.Lipid metabolism also occurs in plants, though the processes differ in some ways when compared to animals.[8] The second step after the hydrolysis is the absorption of the fatty acids into the epithelial cells of the intestinal wall.[6] In the epithelial cells, fatty acids are packaged and transported to the rest of the body.[9]
Metabolic processes include lipid digestion, lipid absorption, lipid transportation, lipid storage, lipid catabolism, and lipid biosynthesis. Lipid catabolism is accomplished by a process known as beta oxidation which takes place in the mitochondria and peroxisome cell organelles.
De Novo Synthesis of fatty acids | Biosynthesis Of Fatty Acids |kiransharma204
This presentation contains De Novo Synthesis of fatty acids & Regulation of fatty acid synthesis
Books referred: https://www.amazon.in/Biochemistry-2019-Satyanarayana-Satyanarayana-Author/dp/B07WGHCTKZ/ref=sr_1_1?dchild=1&keywords=satyanarayan+books+biochemistry&qid=1590834248&sr=8-1
Cholesterol Biosynthesis and catabolism for MBBS, Lab. MEd. BDS.pptxRajendra Dev Bhatt
Cholesterol is found exclusively in animals, hence it is often called as animal sterol.
The total body content of cholesterol in an
adult man weighing 70 kg is about 140 g i.e., around 2 g/kg body weight.
The level of cholesterol in blood is related to the development of atherosclerosis & MI.
The digestion of certain fats begins in the mouth, where short-chain lipids break down into diglycerides because of lingual lipase. The fat present in the small intestine stimulates the release of lipase from the pancreas, and bile from the liver enables the breakdown of fats into fatty acids.
A lipid is chemically defined as a substance that is insoluble in water and soluble in alcohol, ether, and chloroform. Lipids are an important component of living cells. Together with carbohydrates and proteins, lipids are the main constituents of plant and animal cells. Cholesterol and triglycerides are lipids.
3. ABSORPTION OF FATS The digestion of fats takes place primarily in the small intestine, with hydrolysis yielding fatty acids and glycerol. Fat/ Phospholipids + H2O pancreatic lipase Fatty acids + glycerol The products of fat digestion pass through: Lacteals of villi Lymphatics Thoracic duct Bloodstream Liver Bloodstream All Parts of the body
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10. In the liver, some fats are changed into phospholipids, so the blood leaving the liver contains both fats anf phospholipids. These phospholipids, such as sphingomyelin and lecithin are necessary for the formation of nerve and brain tissues. Lecithin are also involved in the transportation of the fat to tissue. Cephalin, another phospholipid is involved in the normal clotting of the blood. From the liver some fat goes to cells, where it oxidized to furnish heat and energy. The fat in excess of what the cells need is stored as adipose tissue.
11. OXIDATION of FATS Oxidation of fats involves the oxidation of two products of the hydrolysis: the oxidation of GLYCEROL and FATTY ACIDS Oxidation of glycerol is metabolized through the carbohydrate sequence. Lipids Hydrolysis Glycerol Gluconeogenesis Glucose Pyruvic Acid Acetyl CoA KREBS CYCLE OXIDATIVE PHOSPHORYLATION Production of ATPs
12. Oxidation of Fatty Acids Fatty Acid Acetyl CoA KREBS CYCLE OXIDATIVE PHOSPHORYLATION Production of ATPs There are several theories about oxidation of fatty acids. The original one, proposed by knoop in 1905 and still prefered today, the β -oxidation theory. It involves the oxidation of the second carbon atom from the acid end, β -carbon . And so, it removes two carbon atoms at a time from the fatty chain. That is, an 18-carbon atom fatty acid is oxidized into 16 then to 14 and so on and so forth until the oxidation is complete.
13. For the unsaturated fats, they must be first reduced by some of the dehydrogenases found in cells. Then they can follow the fatty acid cycle for oxidation.
14. ENERGY PRODUCED by Oxidation of Fatty Acids The oxidation of 1g of fat produces more than twice as much energy as the oxidation of 1g of carbohydrate. 1 Acetyl CoA = 12 ATPs Palmitic Acid = 16-carbon molecule = 8 Acetyl CoA = 96 ATPs Palmitic Acid = 7 FADH 2 + 7 NADH ( FADH 2 = 2 ATPs ; NADH = 3 ATPs) 7 FADH 2 (14 ATPs ) + 7 NADH (21 ATPs) = 35 ATPs Initial activation of Fatty Acid = -2 ATPs One molecule of Palmitic Acid = 96+35-2 = 129 ATPs
15. Considering each mole of ATP as requiring 7.6 kcal for formation, 129 x 7.6 kcal, or 980 kcal is needed. The theoretic yield from I mol of palmitic acid is 2340 kcal, so that the efficiency of conversion is 980/2340, or 42 %, with the remainder of the energy being produced by heat. ( Other fatty acids and glycerol are also oxidized, so the net result is that fats produce more energy than do carbohydrates )