This document summarizes different types of deep neck space infections including peritonsillar abscess, parapharyngeal abscess, retropharyngeal abscess, and Ludwig's angina. It describes the etiology, clinical features, examination findings, complications, and treatment for each type of infection. Key information provided includes the most common causative bacteria for each infection, symptoms like pain, swelling and difficulty swallowing, examination findings of swollen areas, and treatments involving antibiotics, incision and drainage, or tracheostomy if the airway is compromised.
Spaces of middle ear and their surgical importanceDr Soumya Singh
one of the imp topics in ENT that should be understood very thoroughly if u want to pursue as an otologist.I tried to simplify the topic with simple diagrams and models for better understanding .
Neck space infections taken from PL. DHINGRA and other sources to cover all o...lordskywalker7878
This presentation covers the important ENT topics of neck space infections with their management and image illustrations. The source is mainly PL. DHINGRA however other sources have been mentioned in the presentation, especially on the images. It is divided into superficial and deep neck infections for clear distinction between the two categories. It is an extremely important topic especially if your goal is towards surgical side of ENT.
Spaces of middle ear and their surgical importanceDr Soumya Singh
one of the imp topics in ENT that should be understood very thoroughly if u want to pursue as an otologist.I tried to simplify the topic with simple diagrams and models for better understanding .
Neck space infections taken from PL. DHINGRA and other sources to cover all o...lordskywalker7878
This presentation covers the important ENT topics of neck space infections with their management and image illustrations. The source is mainly PL. DHINGRA however other sources have been mentioned in the presentation, especially on the images. It is divided into superficial and deep neck infections for clear distinction between the two categories. It is an extremely important topic especially if your goal is towards surgical side of ENT.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
4. Bacteriology
• Grp A beta hemolytic Streptococcus pyogenes most common
organism
• S aureus
• Anaerobic organisms
• Mixed (aerobic & anaerobic)
5. CFs
• Adults *
• u/l*
• General
• septicemia
• Fever ,chills ,rigors , general malaise ,body aches ,nausea & constipation
• Local
• Severe sore throat
• Odynophagia (cant even swallow his own salivadehydrated)
• Drooling of saliva
• Muffled & thick speech (hot potato voice)
• Poor oral hygiene Foul breath
• Ipsilateral ear ache via CN IX
• Trismus spasm of medial pterygoid
6. Examination
• Tonsils pillars & soft palate on the involved side } congested & swollen
• Swollen uvula pushed to one side
• Bulging of soft palate & anterior pillar above the tonsil
• Mucus may be seen covering soft palate
• Cervical ln+
• Torticollis
8. I & D abscess
• Incision and drainage of abscess
• If not responding to maximum dose of IV Abx
• Interval tonsillectomy
• Tonsillectomy 4-6 weeks following an attack of quinsy.
• Abscess or hot tonsillectomy
• 'hot'tonsillectomy instead of incision and drainage
9. Complications
• Aspiration of pus } pneumonitis/lung abscess
• Jugular vein thrombosis
• Spontaneous hemorrhage from jugular vein /carotid a
• Septicemia
• Edema of larynx
• Parapharyngeal abscess
15. PARAPHARYNGEAL ABSCESS
(Abscess of pharyngomaxillary or lateral
pharyngeal space).
• Para pharyngeal space
Medial: Buccopharyngeal fascia covering the constrictor
muscles.
Posterior: Prevertebral fascia covering prevertebral muscles
and transverse processes of cervical vertebrae.
Lateral: Medial pterygoid muscle, mandible and deep surface
of parotid gland.
16.
17.
18. • Styloid process and the muscles attached to it divide the
parapharyngeal space into anterior and posterior compartments..
19. Lateral
parapharyngeal
space
anterior
posterior
Anterior compartment is
related to tonsillar fossa medially and medial pterygoid muscle
laterally
Posterior compartment is related to posterior part of lateral
pharyngeal wall medially and parotid gland laterally. Through
the posterior compartment pass the carotid artery, jugular
vein, IXth, Xth, XIth, XIIth cranial nerves and sympathetic trunk.
20. Cause of parapharyngeal abscess
• Tonsillectomy or tonsillitis mc cause
• Infection or extraction of lower 3rd molar teeth
21. C/F parapharyngeal abscess
• 60 % develop it as a complication of tonsillitis
• 40 % from extraction of teeth (lower 3rd molar teeth)
• Medial displacement of tonsil
• Trismus d/t spasm of medial pterygoid
• Bulge behind posterior pillar of tonsil
• Swelling behind angle of jaw
• In the neck @ posterior part of middle third of SCM
24. Retropharyngeal space is divided in to
compartment called space of gillet
Each lateral space contains
retropharyngeal lymph
nodes, which usually
disappear at
3–4 years of age
25. Lymph nodes in retropharyngeal space are called
glands of henle disappears by 3-4 yrs
26. The space behind the prevertebral fascia and in
front of
the vertebral bodies is called prevertebral space.
27. • Retropharyngeal space
• Opens in to superior
mediastinum posterior
mediastinum
• Prevertebral space
• Continues upto T1 to T3 where
prevertebral fascia fuses with
upper throracic vertebra
28.
29. Acute retropharyngeal abscess
• d/t suppuration of LN in retropharyngeal space (glands of henle) ie in
space of gillette produces paramedian unilateral bulge in the
posterior pharyngeal wall
• LN regress by 5 years of age therefore acute retropharyngeal
abscess is common in children
31. c/c retropharyngeal abscess
• Secondary to TB spine abscess collects in prevertebral space
(danger space)central bulge
• Also arise d/t TB of LN of retropharyngeal space properparamedian
u/l bulge
• Rx
• I & D followed by full course of ATT
32. Retropharyngeal
abscess
• Widening of retropharyngeal
space (more than ¾ th of
diameter of cervical vertebra)
• Straightening of cervical spine
• Presence of gas shadow
Presence of gas shadow
Straightening of
cervical spine
Widening of
retropharyngeal
space
34. • Ludwig's angina is infection of submandibular space.
• Rapidly progressive cellulitis
• Usually begins in submandibular space & spreads to involve
sublingual space
39. Dental infections. Theyaccount for 80% of the cases. Roots of premolars
often lie above the attachment of mylohyoid and cause
sublingual space infection while roots of the molar teeth extend up to or
below the mylohyoid line and primarily cause submaxillary space infection
41. Etiology
• Mixed infections involving both aerobes and anaerobes are common.
• Alpha haemolytic Streptococci, Staphylococci, and bacteroides groups are
common. RarelyH. influenzae, Esch. coli and Pseudomonas are seen.
42. • Rx
• Systemic Abx
• I&D only if not relieved by Abx
• Tracheostomy in case of endangered airway
43. Complications of ludwigs angina
• Aspiration & pneumonia
• Airway obstruction d/t laryngeal edema
• Spread of infection to parapharyngeal & retropharyngeal space
44. Vincents angina
• Ulceration of mucosa over mouth
tonsil pharynx
• Presence of abundant fusiform
bacilli
• Development of membrane
• Greyish black slough which bleed
whenremoved