This document discusses the anatomy, etiology, evaluation, and management of iatrogenic facial nerve injury. It describes the segments of the facial nerve and provides surgical landmarks. Common causes of facial nerve palsy include Bell's palsy, trauma, infection, tumors, and iatrogenic injury during procedures like mastoidectomy or parotid surgery. Evaluation involves tests like ENoG and EMG to determine the severity of injury. Management depends on the timing and location of injury, and may involve supportive care, steroids, nerve decompression, repair, grafting, or muscle transposition procedures. The goal is to restore facial muscle function through reinnervation of the nerve.
Sinus tymapni shape and depth can influence surgical approach in cholesteatoma surgery. In the case of a shallower ST, an exclusive endoscopic exploration is chosen; while in the case of a deeper ST, a retrofacial approach is usually preferred.
This is a presentation I used for my seminar on 'Phonosurgery' on 4th November, 2015. I hope they are useful to you. Constructive as well as Destructive criticism welcomed.
Maxillectomy and craniofacial resection Mamoon Ameen
all maxillectomy types in detail and maxillofacial resection ,indications ,contraindications ,preoperative asssessment and detail techniques and rehabilitations
Spaces of middle ear and their surgical importanceDr Soumya Singh
one of the imp topics in ENT that should be understood very thoroughly if u want to pursue as an otologist.I tried to simplify the topic with simple diagrams and models for better understanding .
Cavity obliteration is a procedure done at the end of Mastoidectomy to get a cavity-less mastoid cavity thus solving the problem of discharging post-operative cavity.
Sinus tymapni shape and depth can influence surgical approach in cholesteatoma surgery. In the case of a shallower ST, an exclusive endoscopic exploration is chosen; while in the case of a deeper ST, a retrofacial approach is usually preferred.
This is a presentation I used for my seminar on 'Phonosurgery' on 4th November, 2015. I hope they are useful to you. Constructive as well as Destructive criticism welcomed.
Maxillectomy and craniofacial resection Mamoon Ameen
all maxillectomy types in detail and maxillofacial resection ,indications ,contraindications ,preoperative asssessment and detail techniques and rehabilitations
Spaces of middle ear and their surgical importanceDr Soumya Singh
one of the imp topics in ENT that should be understood very thoroughly if u want to pursue as an otologist.I tried to simplify the topic with simple diagrams and models for better understanding .
Cavity obliteration is a procedure done at the end of Mastoidectomy to get a cavity-less mastoid cavity thus solving the problem of discharging post-operative cavity.
Facial nerve traumatic injury and repairsarita pandey
knowledge of anatomy of facial nerve is essential for ENT practitioner,
the worldwide acknowledged high trauma in south africa often results in head and neck injuries, resulting in facial nerve injury
summary of the anatomy, classifications of injuries, and management principles touched upon
indepth surgical procedures out of scope of this slideshow
This presentation talks about the anatomy of facial nerve and the facial nerve palsy. Few diagrams and tables have been taken from Neligan's textbook of Plastic Surgery.
Regional Blocks of the Upper Limb and Thorax RRTRanjith Thampi
Blocks of the UL and Thorax made easy. Most methods mentioned here are modifications and not classical methods used that maybe be required for examination writing purpose.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
7. SURGICAL LANDMARKS
Cochleariform process: lies 1 mm inferior to geniculate
ganglion at anterior end of tympanic segment.
Cog: bony ridge hanging from tegmen tympani lies 1
mm above & posterior to cochleariform process.
Incus short process: 2 mm below lies external genu
Lateral Semicircular Canal: 2 mm Antero-Infero-Medial
lies external genu
Oval window: 1 mm above lies external genu
8. SURGICAL LANDMARKS
Tympano-mastoid suture in posterior canal wall: 5-8 mm
medial lies mastoid segment of facial nerve
Digastric ridge in mastoid tip: leads antero-medially to
mastoid segment of facial nerve
Groove between mastoid & bony E.A.C. meatus: bisected
by facial nerve
Tragal pointer: 1 cm antero-infero-medial is facial nv
Root of styloid process: lateral lies facial nerve
Superior border of posterior belly of digastric: superior &
parallel lies facial nerve
15. ELECTRO-PHYSIOLOGICAL TESTS
• Primary diagnostic modality for surgical decision making
• Estimate the severity of nerve injury ,Prognosis
• Most reliable and objective tests are ENoG and EMG
• Of value only with complete facial paralysis
16. Electro-neuronography
• Measures the amount of intact axons relative to the
healthy side
• Useful between 4 and 21 days of onset of paralysis
• Degeneration > 90% correlated with poor prognosis
17. Electromyography
• Needle electrodes placed within the facial musculature
measures spontaneous and voluntary electrical activity in
the facial muscle
• Assessing the muscle denervation and reenervation
• adjunct to ENoG if surgical intervention is being considered
• Polyphasic action potentials indicate muscle reinnervation
• Fibrillation potentials detected 2 to 3 weeks after injury
indicate significant muscle denervation and poor recover
18. IATROGENIC TRAUMA
• Parotid surgery
• Middle ear and mastoid surgery
• Cerebellopontine angle tumor surgery
• Temporomandibular joint surgery
19. IATROGENIC TRAUMA
Parotid surgery
• Most common surgery with FN injury is parotidectomy
• The likelihood of temporary facial weakness correlates with tumor location deep to the
plane of the facial nerve, previous parotid surgery, previous sialadenitis .
• All parotid surgery is best undertaken with facial nerve monitoring and at the end of the
procedure the main trunk should be stimulated to confirm continuity.
• If there is no response, the nerve and its branches should be closely inspected for areas of
discontinuity.
20. IATROGENIC TRAUMA
Ear surgery
• The incidence of FN palsy 0.6 and 3.6%
• Most common otologic procedures with FN paralysis
--Mastoidectomy – 55%
-- Tympanoplasty – 14%
• Mechanism - direct mechanical injury or heat
generated from drilling
• Most common area of injury – distal tympanic
segment including the 2nd genu, followed by mastoid
segment
21. MANAGEMENT
Recognized at Surgery:
• When the surgeon recognizes that the nerve has been transected, it should be repaired during
the primary surgery
• No return of function should be anticipated sooner than 4 months after transection of the nerve
• If no recovery is noted by the 8th month, the surgeon should consider re-exploring the nerve to
examine the site of repair
22. MANAGEMENT
Recognized immediate Postoperatively:
• Remove the mastoid dressing and ear pack
• Wait for few hours for LA induced weakness to wear off
• Paralysis persist and surgeon
-unsure about integrity of facial nerve ------Re explore as soon as possible
-sure about integrity of facial nerve _______Wait
23. MANAGEMENT
Recognized immediate Postoperatively:
• High dose steroids – prednisolone at 1mg/kg/day x10 days and then taper
• 72 hours – ENoG to assess degree of degeneration
• >90% degeneration – re-explore
• <90% degeneration – monitor
if worsening paralysis occurs re-explore
• If re-exploration is anticipated, assistance from a more experienced surgical colleague is
advisable
24. • Explain the situation to the patient and his family
• Get Ct scan done
• Intraoperative facial nerve stimulation with EMG monitoring is advisable within
the first 3 weeks .
25. MANAGEMENT
Delayed palsy
• delayed palsy is observed a few days after uneventful middle ear surgery with a reported
incidence of 0.9–1.4 %
• The aetiology is unclear, although reactivation of HSV or VZV is postulated as the underlying
mechanism
• Combined use of prednisone and acyclovir should be considered
• Overall prognosis appears to be good
26. MANAGEMENT OF FACIAL NERVE PARALYSIS
Treatment of facial nerve weakness or paralysis may be :
Supportive
Medical
Surgical
Eye care
Combination of all four
27. Selection of the type of management depend on :
• The cause of the facial paralysis
• Type of injury and its location
• The duration of deficit
28. SURGICAL TREATMENT PROTOCOL
• A. Upto 3 weeks:
Nerve decompression or Nerve repair
• B. 3 weeks - 2 years:
Nerve repair or Nerve transposition
• C. >2yrs with fibrillation in EMG
Nerve repair or Nerve transposition
• D. >2yrs with electrical silence in EMG
Muscle transposition/ Eyelid implant/ Facial sling
29. FACIAL NERVE DECOMPRESSION
Decompression : opening the bony canal and nerve sheath to release pressure and reduce compression on nerve
fibers.
• Performed in severe cases when the facial nerve is seriously deteriorating.
• To be effective, the surgery must be performed within 2 weeks of the onset of symptoms.
Most common approach for facial nerve decompression :
• Transmastoid/Middle cranial fossa approach
• – Transmastoid/Translabyrinthine approach
30. DIRECT NERVE REPAIR
• The most effective procedure for reanimating the paralyzed
face.
• Should be done as soon as possible, before significant
muscle degeneration occurs (preferably < 6 months).
• Can be performed with defect < 17 mm
• • If the stumps of the nerve have a neuroma or appear
crushed, the nerve ends should be “freshened” until
normal appearing nerve is evident.
• Goal is tension free, healthy anastomosis
31. DIRECT NERVE REPAIR
• The nerve stumps should be realigned in fascicular groups without tension.
• The perineurium is sutured together followed by the epineurium using 9-0
or 8-0 monofilament nonresorbable nylon suture .
• Recovery of function begins around 4-6 months and can last up to 2 years
following repair
32. NERVE CABLE GRAFTING
• Integrity of proximal and distal nerve stumps and
facial muscles.
• • There is a gap in the facial nerve that cannot be
primarily repaired.
• Graft should be aprox. 25% longer than needed to
allow for a tension free anastomosis•
• The graft must also be placed in a tissue bed that
is free of scar
33. NERVES MOST COMMONLY USED FOR GRAFTING
• Great auricular nerve
• – Usually in surgical field.
• – Can only harvest 7-10cm of this nerve.
• – Loss of sensation to lower auricle
• Sural nerve
• – Located 1 cm posterior to the lateral malleolus.
• – Can provide 35cm of length.
• – Very useful in cross facial anastomosis.
• – Loss of sensation to lateral calf and foot.
34. NERVE TRANSFERS
• Nerve transposition is also known as facial-hypoglossal transfer
• Used in absence of the main trunk of the facial nerve or in cases of intracranial
nerve damage.
• May be performed immediately or up to several years after the injury
• Requires that the patient have an intact distal nerve segment and facial
musculature suitable for reinnervation which determined by EMG .
• Donor site morbidity
35. NERVE TRANSFERS
• Hypoglossal nerve
– Direct hypoglossal-to-facial graft
• Distal branch of facial nerve is attached to hypoglossal
nerve.
• Complications – atrophy of ipsilateral tongue, difficulties
with chewing, speaking, and swallowing.
– Partial hypoglossal-to-facial jump graft
• Uses a nerve cable graft, to connect the distal end of the
facial nerve to a notch in the hypoglossal nerve
• Much fewer complications, but increased recovery time.
36. CROSS-FACIAL NERVE GRAFTING
• This technique employs a nerve graft (typically the sural nerve) that acts
as a conduit for motor axons from the normal side, contralateral facial
nerve.
Options
___ Single contralateral branch to distal nerve anastomosis.
____ Multiple anastomoses from segmental branches to segmental branches
disadvantages :
• Additional donor site in the leg.
• Violating the normal side of the face.
• Two or more suture lines for the axons to cross.
• Long interval until return of function
37. MUSCLE TRANSPOSITION
(DYNAMIC SLING )
• It is employed when there has been long standing paralysis
and the muscles of facial expression have atrophied.
• Allows patients to have a voluntary smile
Local Muscle Transposition
• Most commonly used The temporalis and masseter muscles
• These may be transposed to the upper and lower lips upper
and lower eyelids and the ala
38. MUSCLE TRANSPOSITION
(DYNAMIC SLING )
TEMPORALIS MUSCLE
• Often used for reanimation of the oral commisure
but has been used for orbital Rehabilitation
• Middle 1/3 of muscle is best for transfer
39. MUSCLE TRANSPOSITION
(DYNAMIC SLING )
MASSETER MUSCLE
• Used when temporalis muscle is not available
• May be preferred due to avoidance of large facial
incision
• Vector of pull on oral commisure is more
horizontal than superior/oblique like temporalis
40.
41. MUSCLE TRANSPOSITION
(DYNAMIC SLING )
Free muscle transfer
• A variety of donor muscles have been described.
• These include the gracilis, latissimus dorsi, pectoralis minor.
• The procedure is performed in two stages
• In the first step, a cross-face nerve graft is performed.
• The second stage is the muscle transfer which is done 9 to 12
months later
42.
43. EYE CARE
• Glasses should be worn whenever the patient outside
• If the eye is dry, we can use eye drops (artificial tears ) .
• Taping and Ointment use during sleep
• In cases of long-standing paralysis, it may be necessary to insert a weight ( gold plate)
into the eyelid to close the eye or perform some other procedure to help the eyelid close
(i.e. tarsorrhaphy).
Polyphasic potential indicate regenrative process & surgical intervention is therefore not indicated
Fibrillation indicate lower motor neuron denervation but viable motor end plates, so surgical intervention needed(to achieve nerve continuity)
Electrical silence indicates atrophy of motor end plates & need for muscle transfer procedure
The incidence of FN palsy has been reported to be between 0.6 and 3.6%
some recovery should begin by 8 months following acute injury and repair and continue for up to 2 years after surgery
, because repairs performed a year or longer after injury rarely result in serviceable function
to re-exploration, it should be performed as soon as possible following the injury to minimize the formation of granulation tissue, inflammation, and scar tissue that tends to obscure the surgical field
Herpes simplex virus
Varecilae zoster virus
Approach to full exposure is based on patient’s auditory
and vestibular status
After 12-18 months, muscle reinnervation becomes less efficient
even with good neural anastomosis
– Some authors have reported improvement with repairs as far out
as 18-36 months