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CEREBRAL PALSY
Prepared by: Mohammed Ahmed Rajab
Introduction
◦ Historically known as static encephalopathy
◦ A group of motor impairment syndromes resulting
from disorders of early brain development.
◦ Often associated with epilepsy and abnormalities of
speech, vision and intellect.
◦ However, many children and adult with CP function
at a high educational and vocational level without
sign of cognitive dysfunction
Epidemiology
◦ CP is the most common and costly form of chronic
motor disability
◦ Prevalence: 2/1000
◦ Prevalence of CP is increased in low birth weight
infants (<1000g)
◦ CP incidence higher in premature and twin birth
Aetiology
•Infection
- German measles
- Shingles
•Diabetes
•Toxemia of
pregnancy
•Rh incompatibility
•Asphyxia
•Birth injury
•Prematurity
Caused by developmental, genetic,
metabolic, ischemic, infections
Antenatal
factors (80%)
Intrapartum
(10%)
Postpartum
(10%)
◦ Very high fever
◦ Brain infection
◦ Head injury
◦ Lack of oxygen
◦ Poisoning
◦ Intracranial
hemorrhage or
blood clot
Risk Factors
◦ Before Pregnancy:
- History of fetal wastage
- Long menstrual cycle
- Maternal thyroid disorder
- Family history of mental
retardation
◦ During Labor and Delivery:
- Premature separation of placenta
◦ During Early Postnatal Period:
- Newborn hypoxic ischemic or
bilirubin (kernicterus)
encephalopathy
◦ During Pregnancy:
- Low socioeconomic status
- Tx of mother with thyroid hormone,
estrogen or progesterone
- Maternal seizure disorder
- Polyhydramnios
- Eclampsia
- Bleeding in 3rd trimester
- Twin gestation
- Congenital malformation
- Fetal growth retardation
- Abnormal fetal presentation
Physiologic
identify forms of motor
impairment
Spastic CP
Dyskinetic CP
Ataxic CP
Mixed CP
Distribution
identify location of
musculoskeletal involvement
Spastic diplegia
Spastic
quadriplegia
Spastic
hemiplegia
Classification
Spastic CP
◦ The most common form of CP (70-
80%)
◦ Due to injury to upper motor neurons
of pyrimidal tract
◦ Often exhibit truncal hypotonia in 1st
year of life
•Characterized by at least 2 of following:
-Abnormal movement pattern
-Increased tone
-Pathologic reflexes (Babinski, hyper-reflexia)
Dyskinetic CP
◦ 10-15%
◦ Result of injury to basal ganglia (associated with kernicterus)
◦ Characterized by variable tonal abnormalities & involuntary
movement (athetosis, chorea)
◦ Fewer seizures & >normal cognitive function
Ataxic CP
◦ <5% of CP cases – rare
◦ Results from cerebellar injury
◦ Abnormalities of voluntary movement and balance
◦ Wide-based, unsteady gait, abnormal muscle tone
Mixed CP
◦ 10-15% of all cases
◦ > 1 type of motor pattern is present
& when 1 pattern does not clearly
dominate another
◦ Associated with > complications:
sensory deficits, seizures, cognitive-
perceptual impairments
Dystonic CP
◦ Uncommon
◦ Characterized by reduced activity and stiff movement
(hypokinesia) and hypotonia
Choreoathetotic CP
◦ Rare
◦ Caused by excess hyperbilirubinemia
◦ Dominated by increased and stormy movement (hyperkinesia)
and hypotonia
Clinical Manifestations
◦ Spectrum of developmental abnormalities
◦ Mental retardation
◦ Epilepsy
◦ Motor handicap
•Visual, hearing, speech, cognitive &
behavioral abnormalities
Diagnosis
◦ History and PE should preclude
progressive disorder of CNS,
degenerative disease, metabolic
disorders, spinal cord tumor,
muscular dystrophy
◦ MRI scan of brain or spinal cord
◦ Test of hearing and visual function
◦ Genetic evaluation
Management
◦ CP cannot be cured
◦ Family support – educate parents
◦ Adjunctive therapy:
- Physiotherapy
- Occupational therapy
- Speech therapy
◦ Surgery
◦ Psychologist or psychiatrist
Nursing Manegment
◦ Early Intervention
◦ • The earlier disabled children are given
rehabilitation and education, the better they are
able to realize their full potential later in life.
◦ - Early intervention can have a really positive
impact on a child’s life.
◦ Physiotherapy
◦ - Physiotherapy is extremely beneficial and the
children love the interaction
◦ Feeding
◦ • Three finger jaw control helps in swallowing
◦ • Speech therapy helps in better swallowing
◦ - Care and dignity when feeding a disabled child
improve trust and ensure a healthy, happy child.
◦ Children with learning disabilities
◦ - Encourage appropriate use of the curriculum and
teacher’s guide for mentally disabled children.
◦ - A teacher using teaching materials she has made
herself and adapted to the individual needs of this
child.
◦ Children with hearing and visual impairments
◦ - Special technical skills and training are to be
provided to help deaf or blind children.
◦ - Teaching self help skills through play for blind
children.
◦ Drugs:
- Oral Dantrolene sodium, benzodiazepines, baclofen
– treat spasticity
- Botulinum toxin
- Levodopa
Thank you!!

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CEREBRAL PALSY

  • 1. CEREBRAL PALSY Prepared by: Mohammed Ahmed Rajab
  • 2. Introduction ◦ Historically known as static encephalopathy ◦ A group of motor impairment syndromes resulting from disorders of early brain development. ◦ Often associated with epilepsy and abnormalities of speech, vision and intellect. ◦ However, many children and adult with CP function at a high educational and vocational level without sign of cognitive dysfunction
  • 3. Epidemiology ◦ CP is the most common and costly form of chronic motor disability ◦ Prevalence: 2/1000 ◦ Prevalence of CP is increased in low birth weight infants (<1000g) ◦ CP incidence higher in premature and twin birth
  • 4. Aetiology •Infection - German measles - Shingles •Diabetes •Toxemia of pregnancy •Rh incompatibility •Asphyxia •Birth injury •Prematurity Caused by developmental, genetic, metabolic, ischemic, infections Antenatal factors (80%) Intrapartum (10%) Postpartum (10%) ◦ Very high fever ◦ Brain infection ◦ Head injury ◦ Lack of oxygen ◦ Poisoning ◦ Intracranial hemorrhage or blood clot
  • 5. Risk Factors ◦ Before Pregnancy: - History of fetal wastage - Long menstrual cycle - Maternal thyroid disorder - Family history of mental retardation ◦ During Labor and Delivery: - Premature separation of placenta ◦ During Early Postnatal Period: - Newborn hypoxic ischemic or bilirubin (kernicterus) encephalopathy ◦ During Pregnancy: - Low socioeconomic status - Tx of mother with thyroid hormone, estrogen or progesterone - Maternal seizure disorder - Polyhydramnios - Eclampsia - Bleeding in 3rd trimester - Twin gestation - Congenital malformation - Fetal growth retardation - Abnormal fetal presentation
  • 6. Physiologic identify forms of motor impairment Spastic CP Dyskinetic CP Ataxic CP Mixed CP Distribution identify location of musculoskeletal involvement Spastic diplegia Spastic quadriplegia Spastic hemiplegia Classification
  • 7.
  • 8.
  • 9. Spastic CP ◦ The most common form of CP (70- 80%) ◦ Due to injury to upper motor neurons of pyrimidal tract ◦ Often exhibit truncal hypotonia in 1st year of life
  • 10. •Characterized by at least 2 of following: -Abnormal movement pattern -Increased tone -Pathologic reflexes (Babinski, hyper-reflexia)
  • 11. Dyskinetic CP ◦ 10-15% ◦ Result of injury to basal ganglia (associated with kernicterus) ◦ Characterized by variable tonal abnormalities & involuntary movement (athetosis, chorea) ◦ Fewer seizures & >normal cognitive function
  • 12. Ataxic CP ◦ <5% of CP cases – rare ◦ Results from cerebellar injury ◦ Abnormalities of voluntary movement and balance ◦ Wide-based, unsteady gait, abnormal muscle tone
  • 13. Mixed CP ◦ 10-15% of all cases ◦ > 1 type of motor pattern is present & when 1 pattern does not clearly dominate another ◦ Associated with > complications: sensory deficits, seizures, cognitive- perceptual impairments
  • 14. Dystonic CP ◦ Uncommon ◦ Characterized by reduced activity and stiff movement (hypokinesia) and hypotonia
  • 15. Choreoathetotic CP ◦ Rare ◦ Caused by excess hyperbilirubinemia ◦ Dominated by increased and stormy movement (hyperkinesia) and hypotonia
  • 16. Clinical Manifestations ◦ Spectrum of developmental abnormalities ◦ Mental retardation ◦ Epilepsy ◦ Motor handicap
  • 17. •Visual, hearing, speech, cognitive & behavioral abnormalities
  • 18.
  • 19. Diagnosis ◦ History and PE should preclude progressive disorder of CNS, degenerative disease, metabolic disorders, spinal cord tumor, muscular dystrophy ◦ MRI scan of brain or spinal cord ◦ Test of hearing and visual function ◦ Genetic evaluation
  • 20. Management ◦ CP cannot be cured ◦ Family support – educate parents
  • 21. ◦ Adjunctive therapy: - Physiotherapy - Occupational therapy - Speech therapy ◦ Surgery ◦ Psychologist or psychiatrist
  • 22. Nursing Manegment ◦ Early Intervention ◦ • The earlier disabled children are given rehabilitation and education, the better they are able to realize their full potential later in life. ◦ - Early intervention can have a really positive impact on a child’s life. ◦ Physiotherapy ◦ - Physiotherapy is extremely beneficial and the children love the interaction
  • 23. ◦ Feeding ◦ • Three finger jaw control helps in swallowing ◦ • Speech therapy helps in better swallowing ◦ - Care and dignity when feeding a disabled child improve trust and ensure a healthy, happy child. ◦ Children with learning disabilities ◦ - Encourage appropriate use of the curriculum and teacher’s guide for mentally disabled children. ◦ - A teacher using teaching materials she has made herself and adapted to the individual needs of this child.
  • 24. ◦ Children with hearing and visual impairments ◦ - Special technical skills and training are to be provided to help deaf or blind children. ◦ - Teaching self help skills through play for blind children.
  • 25. ◦ Drugs: - Oral Dantrolene sodium, benzodiazepines, baclofen – treat spasticity - Botulinum toxin - Levodopa