Carcinoma of the prostate (CaP) is the most common cancer in American men and the second leading cause of cancer death. Most cases originate in the peripheral zone of the prostate. Risk factors include increasing age, African American race, family history, and high dietary fat intake. CaP is typically an adenocarcinoma and is graded using the Gleason system. Local spread can occur through the seminal vesicles, bladder, and rectum. Distant spread is usually to bones, lymph nodes, and lungs. Treatment depends on grade and stage, and may include surgery, radiation therapy, hormone therapy, or watchful waiting.

1. Carcinoma of prostate Prepared by Dr. sarwar N mahmood F.I.C.M.S( urology),F.E.B.U, E.A.U

54. Level Agent route Dose(mg) Frequency Pituitary Diethylstilbesterol Goserlin Goserlin Leuprolide Leuprolide Oral SC SC IM IM 1-3 10.8 3.6 22.5 7.5 Daily Every 3 month Every month Every 3month Every month Adrenal Ketoconazole Oral 400 Daily Testicle Orchiectomy Prostate cell Bicalutamide Flutamide Nilutamide Oral Oral Oral 50 250 150 Daily 3 times a day daily