Many patients present to the ophthalmologist in OPD or ER with Foreign body sensations. many of them are welders. foreign bodies can be of many types like organic, inorganic, metallic, inert etc. removing them is the main stream line of treatment.
Human Toxocariasis is a helminthozoonosis due to the infestation of humans by ascarid larvae belonging to the genus Toxocara (Wilder, 1950).-The first description was made in the early 1950's, and has been regarded as an uncommon paediatric disease. Toxocariasis is the most prevalent helminthiasis in industrialized countries.Their definitive hosts are the domestic dogs and cats
A presentation covering all aspects of Trachoma, one of the oldest infectious disease which is one of the leading causes of preventable blindness. Present day scenario and management.
Many patients present to the ophthalmologist in OPD or ER with Foreign body sensations. many of them are welders. foreign bodies can be of many types like organic, inorganic, metallic, inert etc. removing them is the main stream line of treatment.
Human Toxocariasis is a helminthozoonosis due to the infestation of humans by ascarid larvae belonging to the genus Toxocara (Wilder, 1950).-The first description was made in the early 1950's, and has been regarded as an uncommon paediatric disease. Toxocariasis is the most prevalent helminthiasis in industrialized countries.Their definitive hosts are the domestic dogs and cats
A presentation covering all aspects of Trachoma, one of the oldest infectious disease which is one of the leading causes of preventable blindness. Present day scenario and management.
Pediatric Cortical Visual Impairment: Congenital or acquired brain-based visual impairment with onset in childhood, unexplained by an ocular disorder, and associated with unique visual and behavioral characteristics. (PCVI Society). Presentation made to Illinois College of Optometry NORA and COVD students, faculty and residents.
Leukocoria ( or white pupillary reflex) is an abnormal white reflection from the eye.
Leukocoria is a medical sign for a number of several conditions.
- this presentation at annual conference of the Ophthalmic department, faculty of medicine - Al-Azhar University in association with DOS & EOS Cairo, Egypt January 2017
Toxoplasmosis is systemic disease caused by the organism toxolplasma gondii
Mostly patients have no symptoms and develop immunity to the organism
Congenital or acquired
It is the most common cause of infectious retinochorditis in both adults and children
Cats are definitive hosts
Humans and a variety of other animals serve as intermediate hosts
Transmission:
Through undercooked, infected meat, contaminated water, fruits and vegetables, unpasteurized goat milk from infected animal
Contact with cat feces, cat litter or soil containing oocysts
Transplacental transmission during pregnancy
Blood transfusion or organ transplantation
PENETRATION:
Toxoplasma organisms invade intestinal mucosal cells and initiate infection
Ocular Toxoplasmosis:
CONGENITAL TOXOPLASMOSIS:
It is bilateral in 65-85% and involves macula in 58%
Toxoplasmic infection in consecutive siblings is rare
PRESENTATION OF CONGENITAL TOXOPLASMOSIS:
Retinochoroiditis
Hydrocephalus
Intracranial calcification
Microcephaly
Developmental delay
Vision will be compromised
ACQUIRED TOXOPLASMOSIS:
Acute acquired toxoplasmosis presents with acute febrile illness associated with cervical lymphadenopathy
Hilar and submental lymph node enlargement also may occur
PRESENTATION:
A unifocal area of acute-onset inflammation adjacent to an old chorioretinal scar
Retinal vessels in vicinity of an active lesion may show perivasculitis with diffuse venous sheathing and segmental arterial sheathing
Ocular findings:
Involves; Retina, choroid, retinal vessels, macula, optic nerve, vitreous and anterior uvea
Retinitis with fuzzy retinal edema
Retinochoroiditic scar
Vitreous cells and exudates
Focal retinal vasculitis
Hyperemia of optic nerve head
Cells and flares in anterior chamber
Anterior uveitis
Tretment:
ANTIBIOTIC TREATMENT:
Trimethoprim/sulfamethozaxole
Clindamycin
Pyrimethamine
Azithromycin
This is an overview about parasites infest or affect the human eyes & principles of the diseases thay cause
A medical-student-made presentation for Ain Shams University - Faculty of Medicine - Department of Parasitology
Hope it help you
you can get information about the glaucoma and its possible all types, its signs and symptoms, its pathogenesis, and its treatment (with medicines and with surgery).
you will know that how it affects the eye and causes the visual filed defects.
you will know that how it occurs in children and causes loss of vision.
you can get knowledge about the glaucoma, its different types, and its pathogenesis.......
how to treat it.......
its possible surgeries........
how it damages the eye and causes vision defects....
OCULAR TOXOPLASMOSIS the blinding disease and is classified among the torch i...BARNABASMUGABI
the disease spreads from the cats and causes retinochoroiditis and its a blinding disease aswell.its managed with spiromyscin,folinic acid and incase of retinal detachment,vitrectomy is done
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
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Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Maxilla, Mandible & Hyoid Bone & Clinical Correlations by Dr. RIG.pptx
Toxocariasis
1.
2. A 12-year-old female presented with
sudden onset of diminished vision and
redness of right eye to a private
practitioner who diagnosed her as a
case of acute iridocyclitis.
She was treated with topical mydriatic
(atropine) and topical corticosteroid
(dexamethasone).
Redness of eye improved but
diminution of vision progressed for
which she consulted the department of
ophthalmology at our Government
medical college.
3. HISTORY: There was no history of
ocular trauma or ocular ailment in
past.
O/E: Her general physical and
systemic examination was normal.
Left eye had vision of 6/6 and was
normal on examination. Right eye
had vision of hand movements
close to face and ciliary congestion.
Slit lamp bio microscopic
examination showed exudates in
vitreous cavity. Fundus
examination revealed yellowish
reflex in pupillary area, with hazy
media.
The patient is admitted for further
evaluation.
4. • Leucocoria (also leukokoria or white pupillary
reflex) is an abnormal white reflection from the
retina of the eye.
• Leukocoria resembles eyeshine, but leukocoria can
occur in humans and other animals that lack
eyeshine because their retina lacks a tapetum
lucidum.
• Because of the potential life threatening nature of
retinoblastoma, this condition is usually considered
in the evaluation of leukocoria.
5. Differentials
Leucocoria is a medical sign for a number of
conditions, including:
• Coats disease,
• congenital cataract,
• corneal scarring,
• melanoma of the ciliary body,
• Norrie disease,
• Ocular toxocariasis,
• persistence of the tunica vasculosa lentis (PFV/PHPV),
• retinoblastoma,
• and retrolental fibroplasia.
6. • It is an infestation caused by an intestinal
roundworm of dogs (Toxocara canis) and cats
(Toxocara catis).
• Mostly young children who play with dogs and cats
or eat dirt are infested by the ova of these worms.
• These worms then develop into larva in the human
gut, and produce:
covert toxocariasis
visceral larva migrans
ocular larva migrans
7.
8. Life cycle/Parasitology
Toxocara canis accomplishes its life cycle in dogs, with humans acquiring the infection as
accidental hosts. Unembryonated eggs are shed in the feces of the definitive host . Eggs
embryonate and become infective in the environment . Following ingestion by dogs , the
infective eggs hatch and larvae penetrate the gut wall. In younger dogs, the larvae migrate
through the lungs, bronchial tree, and esophagus; adult worms develop and oviposit in the
small intestine . In older dogs, patent infections can also occur, but larval encystment in
tissues is more common. Encysted stages are reactivated in female dogs during late
pregnancy and infect by the transplacental and transmammary routes the puppies , in
whose small intestine adult worms become established. Puppies are a major source of
environmental egg contamination. Toxocara canis can also be transmitted through ingestion
of paratenic hosts: eggs ingested by small mammals (e.g. rabbits) hatch and larvae penetrate
the gut wall and migrate into various tissues where they encyst . The life cycle is completed
when dogs eat these hosts and the larvae develop into egg-laying adult worms in the small
intestine. Humans are accidental hosts who become infected by ingesting infective eggs in
contaminated soil or infected paratenic hosts . After ingestion, the eggs hatch and larvae
penetrate the intestinal wall and are carried by the circulation to a wide variety of tissues
(liver, heart, lungs, brain, muscle, eyes) . While the larvae do not undergo any further
development in these sites, they can cause severe local reactions that are the basis of
toxocariasis. The two main clinical presentations of toxocariasis are visceral larva migrans
and ocular larva migrans. Diagnosis is usually made by serology or the finding of larvae in
biopsy or autopsy specimens.
9.
10. • Ocular infestation by the larva causes ocular
toxocariasis and is almost always UNILATERAL.
Toxocariasis
Covert Visceral Ocular
Toxocara chronic
endophthalmitis
Posterior pole
granuloma
Peripheral
granuloma
11. • It presents with
leucocoria due to
marked vitreous
clouding.
• Most common
among age group
of 2 – 10 years and
mimics
RETINOBLASTOMA
12. • Presents as a
yellow-white,
round, solitary,
raised nodule,
about 1-2 disc
diameter in size,
located either at
the macula or in the
centro-caecal area.
• Occurs in the age
group between 5
and 15 years of age.
13. • It is situated anterior to the equator.
• May be associated with vitreous band formation.
• Presents from 6 – 40 years of age.
14. Two separate patients with
peripheral granulomas due to
ocular toxocariasis. Note the
prominent, posteriorly extending
retinal folds and, in case A,
extensive exudate.
Two separate patients (A and B)
with healed posterior pole
granulomas due to ocular
toxocariasis. Note the prominent
retinal folds and epiretinal
membrane formation.
15. • Her routine investigations were within normal limits. Vitreous sample showed no microorganism on Gram staining and
KOH preparation. Both bacterial and fungal cultures were sterile.
• The patient was treated with topical gatifloxicin 0.3% (one drop six hourly), dexamethasone 0.1% (one drop two
hourly) and atropine sulphate 1% (one drop three times a day). The patient also received two intravitreal injections of
ceftazidime 2.25 mg/0.1 mL and vancomycin 1 mg/0.1 mL.
• Repeat indirect ophthalmoscopy revealed faint glow and organized exudates in vitreous, thus, possibility of mass in
mid-vitreal cavity or posterior pole granuloma was kept and a B-scan was advised, which revealed multiple echogenic
dot-like opacities of low-to-medium amplitude in mid-and posterior vitreous cavity. In view of high spike in mid-vitreal
cavity on B-scan, a differential diagnosis of right intraocular foreign body was raised and CT scan was advised to rule
out intraocular foreign body and retinoblastoma.
• With this clinical presentation, possibility of ocular toxocariasis was kept in mind. Antibodies specific to Toxocara
purified ES antigen were detected in serum, aqueous and vitreous sample by enzyme-linked immunosorbent assay
(ELISA) and treated with vitreo-retinal surgery.
16. Made on the basis of clinical
picture and ELISA blood test.
17. Medical
• Periocular (posterior sub-tenon) injection of
steriod and systemic steriods.
Surgical
• For unresponsive patients with
endophthalmitis and vitreous band formation:
• Pars plana vitrectomy
18. Most cases of isolated elevated granulomas of the disc or retina are
due to Toxocara.
Virtually all cases of toxocariasis in the United States come from pets.
When suspecting ocular toxocariasis, attempt to elicit a history of
exposure to puppies and soil.
While the systemic form is typically unnoticed and produces no
permanent damage, a similar nematode found in raccoons can also
infect humans and is much more virulent.
19. Bibliography
• Department of Ophthalmology, Chengalpattu
Government Medical College;
• Parson’s textbook of Ophthalmology, Pg. 371;
• A K Khurana’s Comprehensice Ophthalmology, Pg.
164;
• My Parents;
• And as always, Wikipedia and Google search
engine.