Operant conditioning involves learning through consequences of behavior. It focuses on the relationship between behaviors and subsequent outcomes. Edward Thorndike studied operant conditioning through his puzzle box experiments with cats. He placed hungry cats in puzzle boxes and food outside to motivate escape attempts. Initially, cats tried many unsuccessful behaviors randomly. Over repeated trials, cats learned which behaviors like pulling a loop or lever opened the door, and escaped more quickly each time by avoiding unproductive actions. Thorndike's experiments demonstrated the principles of operant conditioning and how behaviors are strengthened or weakened by their consequences.