This document discusses the different scales of measurement in statistics: nominal, ordinal, interval, and ratio scales. It defines each scale and provides examples. The nominal scale provides categorization without rank ordering. The ordinal scale allows for ranking but not quantifying differences. The interval scale quantifies and compares differences but lacks a true zero point. The ratio scale has all properties of interval plus an absolute zero. The scales determine which statistical tests can be used, with nominal being the weakest and ratio being the strongest.
Topic: Frequency Distribution
Student Name: Abdul Hafeez
Class: B.Ed. (Hons) Elementary
Project Name: “Young Teachers' Professional Development (TPD)"
"Project Founder: Prof. Dr. Amjad Ali Arain
Faculty of Education, University of Sindh, Pakistan
Topic: Frequency Distribution
Student Name: Abdul Hafeez
Class: B.Ed. (Hons) Elementary
Project Name: “Young Teachers' Professional Development (TPD)"
"Project Founder: Prof. Dr. Amjad Ali Arain
Faculty of Education, University of Sindh, Pakistan
measurement and scaling is an important tool of research. by following the right and suitable scale will provide an appropriate result of research.this slide show will additionally provide the statistical testing for research measurement and scale.
measurement and scaling is an important tool of research. by following the right and suitable scale will provide an appropriate result of research.this slide show will additionally provide the statistical testing for research measurement and scale.
This presentation is on Measurement and it's scales. There are four different types of scales of measurement, namely, Nominal, Ordinal, Interval and Ratio
Measurement scales are used to categorize and/or quantify variables. This presentation describes the four scales of measurement that are commonly used in statistical analysis. This presentation explains the characteristics of nominal, ordinal, interval, and ratio scales with suitable illustrations.
Understanding data type is an important concept in statistics, when you are designing an experiment, you want to know what type of data you are dealing with, that will decide what type of statistical analysis, visualizations and prediction algorithms could be used.
#data #data types #ai #machine learning #statistics #data science #data analytics #artificial intelligence
What is greenhouse gasses and how many gasses are there to affect the Earth.moosaasad1975
What are greenhouse gasses how they affect the earth and its environment what is the future of the environment and earth how the weather and the climate effects.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
This pdf is about the Schizophrenia.
For more details visit on YouTube; @SELF-EXPLANATORY;
https://www.youtube.com/channel/UCAiarMZDNhe1A3Rnpr_WkzA/videos
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Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...Ana Luísa Pinho
Functional Magnetic Resonance Imaging (fMRI) provides means to characterize brain activations in response to behavior. However, cognitive neuroscience has been limited to group-level effects referring to the performance of specific tasks. To obtain the functional profile of elementary cognitive mechanisms, the combination of brain responses to many tasks is required. Yet, to date, both structural atlases and parcellation-based activations do not fully account for cognitive function and still present several limitations. Further, they do not adapt overall to individual characteristics. In this talk, I will give an account of deep-behavioral phenotyping strategies, namely data-driven methods in large task-fMRI datasets, to optimize functional brain-data collection and improve inference of effects-of-interest related to mental processes. Key to this approach is the employment of fast multi-functional paradigms rich on features that can be well parametrized and, consequently, facilitate the creation of psycho-physiological constructs to be modelled with imaging data. Particular emphasis will be given to music stimuli when studying high-order cognitive mechanisms, due to their ecological nature and quality to enable complex behavior compounded by discrete entities. I will also discuss how deep-behavioral phenotyping and individualized models applied to neuroimaging data can better account for the subject-specific organization of domain-general cognitive systems in the human brain. Finally, the accumulation of functional brain signatures brings the possibility to clarify relationships among tasks and create a univocal link between brain systems and mental functions through: (1) the development of ontologies proposing an organization of cognitive processes; and (2) brain-network taxonomies describing functional specialization. To this end, tools to improve commensurability in cognitive science are necessary, such as public repositories, ontology-based platforms and automated meta-analysis tools. I will thus discuss some brain-atlasing resources currently under development, and their applicability in cognitive as well as clinical neuroscience.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
This presentation explores a brief idea about the structural and functional attributes of nucleotides, the structure and function of genetic materials along with the impact of UV rays and pH upon them.
3. INTRODUCTION
DEFINITION:
Levels of measurement is a classification that describes the
nature of information within the numbers assigned to the variables.
USES:
In any study the researcher makes some measurements to map properties ,
characteristics and attributes of an object on some scale.
For example to know the educational level , income and occupation it is
mapped onto some scale of socio economic status, like low, ,middle and
higher class
Knowing the level of measurement helps the researcher to decide how to
interpret the data from the variable.
These scales play an important role in determining the statistical tests that has
to be carried out on the data.
In ascending order there are 4 scales remembered by an acronym NOIR
4. Nominal scale (‘Name’ in Latin)
• It is the weakest scale of measurement.
• Provides simple, non overlapping categorization of observations based
on characteristics possessed by an object.
• We cannot rank order those categories
• Ex: gender of a patient, numbers for players
• The number assigned is ARBITARY like 1 can be assigned for male and
2 can be assigned for female
6. Ordinal scale(‘Order’ in Latin)
• Provides categorization based on the characteristics possessed by
an object.
• Though the characteristics can be ranked in ascending or
descending order of magnitude, it does not tell how much more or
how much less.
• Ex: ask a person how u feel after marriage , he can say unhappy,
happy or very happy. We cannot say how much more or less the
person is feeling.
• So here it is the order of the values that is important but not the
differences between each one which is unknown.
7. Ordinal Scales
Used in measurement
wherein numbers reflect
the rank order of the
individual or objects
8. INTERVAL SCALE
• It allows not only the rank order but also to quantify and compare the
sizes of differences between them.
• Ex: measurement of temperature in F or C . The mercury in the
thermometer indicates temperature .how many units of mercury
corresponds to the temperature measured.
• The number Zero is present here but it remains arbitrary because it is
not a true zero.
• The zero point does not indicate the absence of temperature .
• One can perform addition or substraction but not multiplication and
division on the data measured on interval scale.
9. Interval Scale
Provides numbers that reflect differences
among items.
Measurement units are equal.
Has no reference to zero
AS has meaning
10. Ratio scale
• It is the ultimate , the highest level of measurement and most
important
• It has an ABSOLUTE ZERO
• It tells the exact value between the units.
• With a ratio scale we can compare both differences in scores
• Ex: the difference between 10 and 20 kgs is the same AS that of
20 and 30 kgs.
• Similarly money is measured on a ratio scale. Money has a true
zero, like if a person has zero money it indicates the absence of
money.
• It has all the mathematical properties of the number system.
13. Table showing the criteria met by various
scales…..
SCALE INDICATES
DIFFERENCE
INDICATES
DIRECTION
OF
DIFFERENCE
INDICATES
AMOUNT OF
DIFFERENCE
ABSOLUTE
ZERO
NOMINAL YES - - -
ORDINAL YES YES - -
INTERVAL YES YES YES -
RATIO YES YES YES YES
14. SUMMARY OF PROPERTIES OF
FOUR LEVELS OF MEASURMENT
DESCRIPTION CAHRACTERIS
TICS
EXAMPLE PERMISSABLE STATS GRAPHS
NOMINAL Organized into
categories but not
in order
Contains no
magnitude,
just names
Eye
color(black
/brown),ge
nder(male
/female)
DS: Freq & %,Mode
IS:Chisquare
Bar and
pie
ORDINAL Organized and
arranged in rank
order, however
difference
between data
values cannot be
organized
Reflects only
magnitude,
doesn’t have
intervals or an
absolute zero.
Has a rank
order.
Levels of
depression
, stages of
cancer
DS: Freq & %,Mode,
Median
IS: Rank order
correlation
Bar and
pie
15. DESCRIPTION CAHRACTERIS
TICS
EXAMPLE PERMISSABLE STATS GRAPHS
INTERVAL Categorized and
ranked with
meaningful
intervals between
measurements.
No true zero
point.
Possess
magnitude,
fixed size of
intrvals
between data
points , but no
absolute zero.
Temperatu
re on F or
C , IQ
scores.
DS: Freq & %,Mean,
Mode,Median,SD,Ske
wness and kurtosis.
IS:ANOVA,t test
Bar and
pie,
histogra
m
RATIO Categorized and
ranked with
meaningful
intervals between
measurements.
And has an
inherent zero
point.
Reflects only
magnitude,
have intervals
has an
absolute zero.
Has a rank
order.
Height ,
weight,
currency
DS:
Mean,SD,skewness,
kurtosis.
IS: Coefficient of
variation and t test
Histogra
m
SUMMARY OF PROPERTIES OF FOUR LEVELS
OF MEASURMENT