Raynaud's disease is a rare disorder characterized by vasospasm of the arteries, causing reduced blood flow to the fingers and toes. It typically presents as color changes in the affected areas in response to cold temperatures or stress. There are two types - primary Raynaud's, where the cause is unknown, and secondary Raynaud's, which is associated with other medical conditions like scleroderma or injury. Symptoms may include numbness, pain, and skin ulcers or gangrene in severe cases. Treatment focuses on avoiding triggers and using vasodilators to improve circulation.
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Cardiogenic shock : Medical Surgical NursingRaksha Yadav
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presentation is designed for Nursing students and it gives a brief
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A condition in which some areas of the body feel numb and cool in certain circumstances.
In Raynaud's phenomenon, smaller arteries that supply blood to the skin constrict excessively in response to cold, limiting blood supply to the affected area.
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Raynaud's disease, also known as Raynaud's phenomenon or Raynaud's syndrome, is a condition that affects blood flow to certain parts of the body—usually the fingers and toes. In Raynaud's disease, smaller arteries that supply blood to the skin constrict excessively in response to cold or stress, limiting blood supply to affected areas (vasospasm). This can lead to numbness, tingling, and color changes in the affected areas, typically turning them white or blue.
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Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
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Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
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Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
The hemodynamic and autonomic determinants of elevated blood pressure in obes...
Raynauds disease
1.
2. Raynaud's is a rare disorder that affects the
arteries.
Raynaud's is also called a disease, syndrome,
or phenomenon.
Vasospasm, which is a narrowing of the blood
vessels.
Vasospasm of the arteries reduces blood flow
to the fingers and toes.
Also may occur at the tip of ears and nose.
3.
4.
5. Primary Raynaud’s / Raynaud’s disease the
causes is not known.(idiopathic)
Secondary Raynaud’s / Raynaud’s
phenomenon where the causes are known.
7. ETIOLOGY OF SECONDARY RAYNAUD’S
Scleroderma
Lupus (Lupus is a chronic, autoimmune
disease that can damage any part of the body
(skin, joints, and/or organs inside the body).
Rheumatoid arthritis
8. Sjogren's syndrome
Diseases of the arteries.
Carpal tunnel syndrome(it is numbness,
tingling, weakness, and other problems in
hand because of pressure on the median
nerve in your wrist)
11. Expose to cold /
triggering factor
Small arteries at
fingers and toes
vasospasm
Become pale,
less blood flow
and low O2
supply
Warm up
(arteries dilate)
Blood flow
increase, high O2
supply
Color change to
bright red
Affected area is
warm and
throbbing pain
12. $ During the Raynaud’s attack, arteries become
narrow and no blood supply to the area, this
will cause :
# Turn pale or white and then blue
# Feel numb, cold, or painful
# Turn red, throb, tingle, burn, or feel numb as
blood flows back to the affected area
13.
14. Cold Stimulation Test
Nailfold Capillaroscopy
Erythrocyte sedimentation rate (ESR or "sed
rate")
C-reactive protein (CRP) tests
17. Complete lost of blood to the digits will cause:
deformities of fingers and toes
gangrene
ulcer
18. Stop smoking
Exercise
Control stress
Avoid caffeine
Take care of feet and hand
Dress warmly outdoors
19.
20. NURSING DIAGNOSIS: Ineffective peripheral
tissue perfusion related to
lack of blood supply to
extremities.
GOAL: Increased arterial blood supply to
extremities.
21. NURSING
INTERVENTION
RATIONALE
Assess the patient for the blood
circulation,colour and sensation at the
extremities.
For further investigation and treatment.
Apply warm compress at the affected
area
To promote good blood circulation
Administer the medication as prescribed
by doctor such as vasodilator, calcium
channel blockers and alpha blockers
To vasodilate the blood vessel and
increase blood supply to the extremities
Monitor the blood circulation to the
extremities every two hourly (circulation
chart)
To observe for any further complication
Encourage patient to perform extremities
exercises while sitting or during work
Muscular exercises promotes blood flow
and the development of collateral
circulation
22. EVALUATION : Patients extremities are warm to
touch, improve in colour and
no complain of numbness .
23. NURSING DIAGNOSIS : Anxiety related to
disease process.
GOAL : To reduce the anxiety level of patient
24. NURSING
INTERVENTION
RATIONALE
Asses the patient’s anxiety level by
observing clients behavior e.g crying
facial expression and anxious.
For further investigation
Reinforce doctor’s explainations to
patient by using the non medical term
To increase the understanding of patient
about the disease.
Provide moral and emotional support to
patient
To provide patient psychological comfort
Encourage diversional theraphy e.g
watching tv, listening songs
To deviate client’s mind away from the
disease and to avoid patient get mentally
stress
25. EVALUATION : Patient’s anxiety level decrease
and client is more clear about
the disease.
26. NURSING DIAGNOSIS : Deficient knowledge
regarding self-
care
activities.
GOAL : The patient will able to carry out daily
activity by understanding the
health education given by nurse
based on the disease.
27. NURSING
INTERVENTION
RATIONALE
Assess client knowledge level For the nurses to give adequate health
education to the client
Encourage patient to perform extremities
exercises.
To promote the blood flow to the affected
area
Advise patient to place the fingers or toe
under the warm water during the attack.
The warm water will vasodilate and
encourage the blood flow.
Advise patient to stop smoking Reducing the risk factor may reduce
symptoms or slow the disease
progression
Advise patient not to wear tight wrist
band or watch and clothings
Constrictive clothing and accessories
impede circulation.
28. EVALUATION : Client is able to carry out the
daily activities by implementing the
health education given.
29. Raynaud's sometimes is called a disease,
syndrome, or phenomenon.
Is a narrowing of the blood vessels.
Vasospasm of the arteries reduces blood flow to
the fingers and toes.
In people who have Raynaud's, the disorder
usually affects the fingers.
In about 40 percent of people who have
Raynaud's, it affects the toes. Rarely, the disorder
affects the nose, ears, nipples, and lips.
30. Has two type of raynaud that is primary and
secondary raynaud disease
In both types of Raynaud's, even mild or brief
changes in temperature can cause Raynaud's
attacks.
People with severe Raynaud's can develop skin
sores or gangrene from prolonged or repeated
Raynaud's attacks.
It can be treated e.g. by placing the hand under
warm water to vasodilate