SlideShare a Scribd company logo
RELIANCE INSTITUTE OF
NURSING LIMTARA
DHAMTARI (C.G)
TOPIC - RAYNAUD’S
DISEASE
• PRESENTED BY-
• OM VERMA
• ASSISTANT PROFESSOR
Raynaud’s disease
Raynaud’s phenomenon is
a form of intermittent
arteriolar vasoconstriction
that results in coldness,
pain & pallor of the
fingertips or toes.
There are 2 forms of this
disorders :-
1. Primary or idiopathic
Raynaud’s disease
2. Secondary Raynaud’s
syndrome
Definition
“Raynaud's phenomenon (RP) is a
condition resulting in a particular series of
discolorations of the fingers and/or the
toes after exposure to changes in
temp.(cold or hot) or emotional events.
Skin discoloration occurs b’coz an
abnormal spasm of the blood vessels
causes a diminished blood supply
to the local tissues.”
according to luck man.s
According to joyce M black
The Raynaud’s phenomenon is
used to refer to localized,
intermittent episodes of
vasoconstriction of small arteries of
the feet and hands that cause color
and temperature changes
According to lippin cott
• It is a recurrent vasospasm of the
fingers and toes and usually occurs
in response to stress or cold
exposure
Incidence
Raynaud’s disease is
most common in women between 16
& 40 yrs. Of age & it occurs more
frequently in cold climates & during
the winter.
• CLASSIFICATION
• • Primary
• occurrence of the vasospasm alone,
with no association with another illness
• • Secondary
• secondary to other conditions, most
commonly an autoimmune disease
• eg- SLE, rhematoid arthrits
Etiology
1) Primary Raynaud’s disease :-(symptoms
are idiopathic)
Hereditary
Smoking worsens frequency and intensity of
attacks & there is a hormonal component.
Caffeine
2) Secondary Raynaud’s (Syndrome) :-
Connective tissue disorders
Eating disorders
Obstructive disorders
Drugs
Occupation
Others
• Working with vibrating machinery - the
fingers may go into spasm. This is due
to an intermittent lack of blood supply
to the fingers.
• o Emotional distress
• o Exposure to the cold
• • Exposure to chemicals such as PVC,
Silica.
• • Smoking
• • Autoimmune disease
Risk factors
1) The risk factors for primary Raynaud's include :-
Gender,Age,Family history & Living in a cold climate
2) The risk factors for secondary Raynaud's include
:-
 Age
 Certain diseases and conditions
 Injuries to the hands or feet
 Exposure to certain workplace chemicals
 Repetitive actions with the hands
 Certain medicines
 Smoking
 Living in a cold climate
Clinical manifestation
1. Intermittent arteriolar vasoconstriction resulting in
coldness, pain, pallor.
2. Involvement of the fingers appears to be asymmetric;
thumbs are less often involved.
3. Characteristic color changes: white-blue-red.
a) White- blanching, dead-white appearance if spasm is
severe
b) Blue - cyanotic,because of pooling of deoxygenated
blood during vasospasm.
c) Red – because of oxygenated blood
returns to the digits after the
vasospasm stops.
4. Occasionally,ulceration of the fingertips.
5. Numb, prickly feeling or stinging pain
upon warming or relief of stress.
• Signs and Symptoms
• • The attacks can affect the fingers and toes,
and rarely the nose, ears,or lips.
• • The affected body parts will usually have two
or more of the following changes:
• • Look pale due to lack of blood flow
• • Look bluish due to a lack of oxygen
• • Feel numb, cold, or painful
• • Redden as blood returns to the affected area
• Patients often describe 3 phases
of change –
• • initial white (vasoconstriction),
• • followed by blue (cyanosis),
• • then red (rapid blood reflow
Diagnostic evaluation
1. History taking
2. Physical examination
3. Cold Stimulation Test
4. Nail-fold Capillaroscopy
5. Digital artery pressure
6. Doppler ultrasound
7. Complete blood count
8. Blood test for urea & electrolytes
9. Thyroid function tests
10.An auto-antibody screen tests
• Diagnosis
• • History collection
• Obtain a history of injury or frostbite
• occupational history eg- jackhammers
• Industrial exposure to polyvinyl chloride
• Autoimmune disorders
• • Physical examination
• observe the colur of digits, ulcers
• Examine nailfold capillaries under magnification help
• diagnose underlying autoimmune disorders
• Laboratory investigation
• Complete blood count
• ESR
• Antinuclear antibody - May be positive
in autoimmune disorders and should be
obtained in patients with features of these
disorders.
• Rheumatoid factor - May be elevated in
• rheumatoid arthritis, other autoimmune
disorders
• History taking :-Clinical symptoms must
last atleast 2 yrs. To confirm the
diagnosis.& Ask about the risk factors of
the disease.
• Physical examination :- Check the finger &
toes for blood circulation.
• Cold Stimulation Test :-A cold stimulation
test can be used to trigger Raynaud's
symptoms.For this test,a small device that
measures temperature is taped to
fingers.hands are then exposed to cold—
they're usually briefly put into ice
water.hands are then removed from the
cold & the device measures how quickly
fingers return to their normal
temperature.If you have Raynaud's,it may
take more than 20 minutes for fingers to
return to their normal temperature.
• Nail-fold Capillaroscopy :-For this
test,doctor puts a drop of oil at the base of
fingernail.He or she then looks at
fingernail under a microscope.If doctor
sees abnormal arteries,it may mean you
have a disease linked to Raynaud's.
• Digital artery pressure :- pressures are
measured in the arteries of the fingers
before and after the hands have been
cooled. A decrease of at least 15 mmHg is
diagnostic (positive).
• Doppler ultrasound :-to assess blood flow.
• Complete blood count :- this can
reveal a
normocytic anemia suggesting
the anemia or renal failure
• Blood test for urea and electrolytes:-
this can reveal renal impairment.
• Thyroid function tests :- this can
reveal hypothyroidism.
• An auto-antibody screentests:-
for rheumatoid factor,Erythrocyte
sedimentation rate and C-reactive
protein,which may reveal specific
causative illnesses or a generalised
inflammatory process.
• Medical Management
• • Avoiding the particular stimuli (eg, cold,
tobacco)
• that provoke vasoconstriction
• • Calcium channel blockers
• eg- Nifidipine
• 30-120 mg of the extended-release
• formulation taken once daily
• • Topical nitroglycerin (1% or 2%)
• Medical management :-
• Avoiding the particular stimuli such as cold
&tobacco,that provoke vasoconstriction is a primary
factor in controlling Raynaud's phenomenon.
• Longer acting calcium channel blocker such as
Nifedipine, Amlodipine may be used to prevent
vasospasm.
• Antiplatelet agents such as Aspirin or Dipyridamole
(persantine) may be given to prevent total occlusion.
• Sympathectomy (interrupting the sympathetic nerves
by removing the sympathetic ganglia or dividing their
branches) such as Reserpine (serpasil),Guanethidine
or Prazosin may be helpful.
•
• Nursing Management
• • The client is encouraged to avoid exposure
to cold.
• • Avoid repetitive hand movements and
stressful situations.
• • Quit smoking and avoids secondary smoke
as nicotine is potent vasoconstrictor.
• • Stress management techniques ex.
biofeedback
• • Assist in alleviating some distress from the
condition
• Complication :-
• Atrophy of skin & muscles
• Ulceration
• Gangrene
Medical management
1. Avoiding particular stimuli
i.e. cold & tobacco
2. Calcium channel blocker
such as Nifedipine,
Amlodipine may be used
3. Antiplatelet agents such as
Aspirin may be used.
4. Sympathectomy may be
helpful.
Alternative & experimental approaches
1. The Ayurvedic oil preparation Mahanarayan
Oil has been used very successfully in many
cases as a vasodilater when applied daily to
affected areas.
2. Two separate gels combined on the fingertip
increased blood flow in the fingertips by
about three times.One gel contained 5%
sodium nitrite and the other contained 5%
ascorbic acid.The milliliter of combined gel
covered an area of 3 cm².The gel was wiped
off after a few seconds.
3. Fish oil supplements which contain long-
chain omega-3 fatty acids may help to
control symptoms of primary Raynaud's.
Nursing management
1. Minimizing Sensory Alteration
2. Relieving Pain
3. Patient Education and
Health Maintenance
Slide for raynaud's disease

More Related Content

What's hot

Pulmonary edema
Pulmonary edemaPulmonary edema
Pulmonary edema
anishcrist
 
care of CABG patient.ppt
care of CABG patient.pptcare of CABG patient.ppt
care of CABG patient.ppt
kamal199155
 
Cardiac assessment ppt
Cardiac assessment pptCardiac assessment ppt
Cardiac assessment pptManali Solanki
 
Raynaud's disease
Raynaud's diseaseRaynaud's disease
Raynaud's disease
Mary Lalitha Kala C
 
Cardiomyopathy
Cardiomyopathy Cardiomyopathy
Cardiomyopathy
SUDESHNA BANERJEE
 
Peripheral vascular disease
Peripheral vascular diseasePeripheral vascular disease
Peripheral vascular disease
shemil Palliyal
 
raynauld's disease
raynauld's diseaseraynauld's disease
raynauld's disease
Ashu Somkuwar
 
Raynauds disease
Raynauds diseaseRaynauds disease
Raynauds disease
Baljinder Singh
 
Valvular heart disease
Valvular heart diseaseValvular heart disease
Valvular heart disease
MR. JAGDISH SAMBAD
 
Pulmonary embolism1
Pulmonary embolism1Pulmonary embolism1
Pulmonary embolism1
GAMANDEEP
 
coronary artery disease (CAD)
coronary artery disease (CAD)coronary artery disease (CAD)
coronary artery disease (CAD)
Pallavi Lokhande
 
Hyponatremia
HyponatremiaHyponatremia
Hyponatremia
Khushi Devgan
 
coronary artery disease
coronary artery diseasecoronary artery disease
coronary artery disease
Sagar Masne
 
Cardiac tamponade
Cardiac tamponadeCardiac tamponade
Cardiac tamponade
ANILKUMAR BR
 
Aneurysm
AneurysmAneurysm
Aneurysm
Jinumol Jacob
 
Medicated-Bath
Medicated-BathMedicated-Bath
Medicated-Bath
dhanasekar187
 
Cardiac dysrhythmias
Cardiac dysrhythmiasCardiac dysrhythmias
Cardiac dysrhythmias
Chinna Chadayan
 
Peripheral artery disease nikku
Peripheral artery disease nikkuPeripheral artery disease nikku
Peripheral artery disease nikku
Nikhil Vaishnav
 
Rheumatic heart disease
Rheumatic heart diseaseRheumatic heart disease
Rheumatic heart disease
Abhay Rajpoot
 
Cardiac tamponade
Cardiac tamponadeCardiac tamponade
Cardiac tamponade
Jinumol Jacob
 

What's hot (20)

Pulmonary edema
Pulmonary edemaPulmonary edema
Pulmonary edema
 
care of CABG patient.ppt
care of CABG patient.pptcare of CABG patient.ppt
care of CABG patient.ppt
 
Cardiac assessment ppt
Cardiac assessment pptCardiac assessment ppt
Cardiac assessment ppt
 
Raynaud's disease
Raynaud's diseaseRaynaud's disease
Raynaud's disease
 
Cardiomyopathy
Cardiomyopathy Cardiomyopathy
Cardiomyopathy
 
Peripheral vascular disease
Peripheral vascular diseasePeripheral vascular disease
Peripheral vascular disease
 
raynauld's disease
raynauld's diseaseraynauld's disease
raynauld's disease
 
Raynauds disease
Raynauds diseaseRaynauds disease
Raynauds disease
 
Valvular heart disease
Valvular heart diseaseValvular heart disease
Valvular heart disease
 
Pulmonary embolism1
Pulmonary embolism1Pulmonary embolism1
Pulmonary embolism1
 
coronary artery disease (CAD)
coronary artery disease (CAD)coronary artery disease (CAD)
coronary artery disease (CAD)
 
Hyponatremia
HyponatremiaHyponatremia
Hyponatremia
 
coronary artery disease
coronary artery diseasecoronary artery disease
coronary artery disease
 
Cardiac tamponade
Cardiac tamponadeCardiac tamponade
Cardiac tamponade
 
Aneurysm
AneurysmAneurysm
Aneurysm
 
Medicated-Bath
Medicated-BathMedicated-Bath
Medicated-Bath
 
Cardiac dysrhythmias
Cardiac dysrhythmiasCardiac dysrhythmias
Cardiac dysrhythmias
 
Peripheral artery disease nikku
Peripheral artery disease nikkuPeripheral artery disease nikku
Peripheral artery disease nikku
 
Rheumatic heart disease
Rheumatic heart diseaseRheumatic heart disease
Rheumatic heart disease
 
Cardiac tamponade
Cardiac tamponadeCardiac tamponade
Cardiac tamponade
 

Similar to Slide for raynaud's disease

Raynaud's-Disease.ppt
Raynaud's-Disease.pptRaynaud's-Disease.ppt
female Raynaud
female Raynaudfemale Raynaud
female Raynaud
muhammad al hennawy
 
Raynaud’s phenomenon
Raynaud’s phenomenonRaynaud’s phenomenon
Raynaud’s phenomenonFardan Qadeer
 
Raynaud's phenomenon
Raynaud's  phenomenonRaynaud's  phenomenon
Raynaud's phenomenon
zahra seraji
 
Raynauds disease
Raynauds diseaseRaynauds disease
Raynauds disease
RumshaUmmeHani
 
Cold Hands? It could be Raynaud’s Phenomenon
Cold Hands? It could be Raynaud’s PhenomenonCold Hands? It could be Raynaud’s Phenomenon
Cold Hands? It could be Raynaud’s Phenomenon
The Lifesciences Magazine
 
Raynauds phenomenon- nursing
Raynauds phenomenon- nursingRaynauds phenomenon- nursing
Raynauds phenomenon- nursing
EDWINjose43
 
Raynauds phenomenon
Raynauds phenomenonRaynauds phenomenon
Raynauds phenomenon
Akhil Raj K
 
Raynauds phenomena
Raynauds phenomenaRaynauds phenomena
Raynauds phenomena
Saima Mustafa
 
RAYNAUD'S DISEASE
RAYNAUD'S DISEASERAYNAUD'S DISEASE
RAYNAUD'S DISEASE
ShylaMercy
 
Raynauds disease By_A. Raju_Yadav
Raynauds disease By_A. Raju_YadavRaynauds disease By_A. Raju_Yadav
Raynauds disease By_A. Raju_Yadav
RajYadav238
 
Raynaud Syndrome 4
Raynaud Syndrome 4Raynaud Syndrome 4
Raynaud Syndrome 4Deep Deep
 
Raynauds Phenomenon-Dignosis & Evaluation
Raynauds Phenomenon-Dignosis & Evaluation Raynauds Phenomenon-Dignosis & Evaluation
Raynauds Phenomenon-Dignosis & Evaluation Suneth Weerarathna
 
Raynauds syndrome by Dr.AmrithaAnilkumar
Raynauds syndrome by Dr.AmrithaAnilkumarRaynauds syndrome by Dr.AmrithaAnilkumar
Raynauds syndrome by Dr.AmrithaAnilkumar
Dr. Amritha Anilkumar
 
raynauds.pptx
raynauds.pptxraynauds.pptx
raynauds.pptx
MISSCOM1
 
Acute rheumatic fever
Acute rheumatic feverAcute rheumatic fever
Acute rheumatic fever
rasikapriya Duraisamy
 
Raynauds phenomenon
Raynauds phenomenonRaynauds phenomenon
Raynauds phenomenon
Anusha Rameshwaram
 

Similar to Slide for raynaud's disease (20)

Raynaud's-Disease.ppt
Raynaud's-Disease.pptRaynaud's-Disease.ppt
Raynaud's-Disease.ppt
 
female Raynaud
female Raynaudfemale Raynaud
female Raynaud
 
Raynaud’s phenomenon
Raynaud’s phenomenonRaynaud’s phenomenon
Raynaud’s phenomenon
 
Raynaud's phenomenon
Raynaud's  phenomenonRaynaud's  phenomenon
Raynaud's phenomenon
 
Raynaud's phenomenon
Raynaud's phenomenonRaynaud's phenomenon
Raynaud's phenomenon
 
Raynauds disease
Raynauds diseaseRaynauds disease
Raynauds disease
 
Cold Hands? It could be Raynaud’s Phenomenon
Cold Hands? It could be Raynaud’s PhenomenonCold Hands? It could be Raynaud’s Phenomenon
Cold Hands? It could be Raynaud’s Phenomenon
 
Raynauds phenomenon- nursing
Raynauds phenomenon- nursingRaynauds phenomenon- nursing
Raynauds phenomenon- nursing
 
Raynauds phenomenon
Raynauds phenomenonRaynauds phenomenon
Raynauds phenomenon
 
Raynauds phenomena
Raynauds phenomenaRaynauds phenomena
Raynauds phenomena
 
RAYNAUD'S DISEASE
RAYNAUD'S DISEASERAYNAUD'S DISEASE
RAYNAUD'S DISEASE
 
Raynauds disease By_A. Raju_Yadav
Raynauds disease By_A. Raju_YadavRaynauds disease By_A. Raju_Yadav
Raynauds disease By_A. Raju_Yadav
 
Raynaud Syndrome 4
Raynaud Syndrome 4Raynaud Syndrome 4
Raynaud Syndrome 4
 
Raynauds Phenomenon-Dignosis & Evaluation
Raynauds Phenomenon-Dignosis & Evaluation Raynauds Phenomenon-Dignosis & Evaluation
Raynauds Phenomenon-Dignosis & Evaluation
 
Raynauds syndrome by Dr.AmrithaAnilkumar
Raynauds syndrome by Dr.AmrithaAnilkumarRaynauds syndrome by Dr.AmrithaAnilkumar
Raynauds syndrome by Dr.AmrithaAnilkumar
 
raynauds.pptx
raynauds.pptxraynauds.pptx
raynauds.pptx
 
Acute rheumatic fever
Acute rheumatic feverAcute rheumatic fever
Acute rheumatic fever
 
Cv
 Cv Cv
Cv
 
Cv
 Cv Cv
Cv
 
Raynauds phenomenon
Raynauds phenomenonRaynauds phenomenon
Raynauds phenomenon
 

More from OM VERMA

otalgia- JUN 2023 OM VERMA.pdf
otalgia- JUN 2023 OM VERMA.pdfotalgia- JUN 2023 OM VERMA.pdf
otalgia- JUN 2023 OM VERMA.pdf
OM VERMA
 
POISIONING JUN 2023
POISIONING JUN 2023POISIONING JUN 2023
POISIONING JUN 2023
OM VERMA
 
public relation.pdf
public relation.pdfpublic relation.pdf
public relation.pdf
OM VERMA
 
PRENATAL TESTING AND DIAGNOSIS.pdf
PRENATAL TESTING AND DIAGNOSIS.pdfPRENATAL TESTING AND DIAGNOSIS.pdf
PRENATAL TESTING AND DIAGNOSIS.pdf
OM VERMA
 
practical application of genetics in nursing OM VERMA 2022 slide.pdf
practical application of genetics in nursing  OM VERMA 2022 slide.pdfpractical application of genetics in nursing  OM VERMA 2022 slide.pdf
practical application of genetics in nursing OM VERMA 2022 slide.pdf
OM VERMA
 
Neural tube defects and the role of folic acid in Lowering the Risk.pdf
Neural tube defects and the role of folic acid in Lowering the Risk.pdfNeural tube defects and the role of folic acid in Lowering the Risk.pdf
Neural tube defects and the role of folic acid in Lowering the Risk.pdf
OM VERMA
 
MULTIPLE ALLOTS ( ALLELES ) AND BLOOD GROUPS OM VERMA 2023.pdf
MULTIPLE ALLOTS  ( ALLELES ) AND BLOOD GROUPS OM VERMA 2023.pdfMULTIPLE ALLOTS  ( ALLELES ) AND BLOOD GROUPS OM VERMA 2023.pdf
MULTIPLE ALLOTS ( ALLELES ) AND BLOOD GROUPS OM VERMA 2023.pdf
OM VERMA
 
MENDALIAN THEORY OF INHERITANCE AND MULTIPLE BLOOD ALLOTS AND BLOOD GROUPS 20...
MENDALIAN THEORY OF INHERITANCE AND MULTIPLE BLOOD ALLOTS AND BLOOD GROUPS 20...MENDALIAN THEORY OF INHERITANCE AND MULTIPLE BLOOD ALLOTS AND BLOOD GROUPS 20...
MENDALIAN THEORY OF INHERITANCE AND MULTIPLE BLOOD ALLOTS AND BLOOD GROUPS 20...
OM VERMA
 
Maternal prenatal and genetic influences on development of defect and disease...
Maternal prenatal and genetic influences on development of defect and disease...Maternal prenatal and genetic influences on development of defect and disease...
Maternal prenatal and genetic influences on development of defect and disease...
OM VERMA
 
MATERNAL AGE,MATERNAL DRUG THERAPY PRENATAL TEST AND DIAGNOSIS.pdf
MATERNAL AGE,MATERNAL DRUG THERAPY PRENATAL TEST AND DIAGNOSIS.pdfMATERNAL AGE,MATERNAL DRUG THERAPY PRENATAL TEST AND DIAGNOSIS.pdf
MATERNAL AGE,MATERNAL DRUG THERAPY PRENATAL TEST AND DIAGNOSIS.pdf
OM VERMA
 
infertility.pdf
infertility.pdfinfertility.pdf
infertility.pdf
OM VERMA
 
Inborn Errors of Metablism.pdf
Inborn Errors of Metablism.pdfInborn Errors of Metablism.pdf
Inborn Errors of Metablism.pdf
OM VERMA
 
Huntington Disease and Mental illness.pdf
Huntington Disease and Mental illness.pdfHuntington Disease and Mental illness.pdf
Huntington Disease and Mental illness.pdf
OM VERMA
 
Hematological Disorders.pdf
Hematological Disorders.pdfHematological Disorders.pdf
Hematological Disorders.pdf
OM VERMA
 
genetic testing inneanates and childern.pdf
genetic testing inneanates and childern.pdfgenetic testing inneanates and childern.pdf
genetic testing inneanates and childern.pdf
OM VERMA
 
HUMAN GENOME PROJECT AND GENE THERAPY.pdf
HUMAN GENOME PROJECT AND GENE THERAPY.pdfHUMAN GENOME PROJECT AND GENE THERAPY.pdf
HUMAN GENOME PROJECT AND GENE THERAPY.pdf
OM VERMA
 
PRENATAL TESTING AND DIAGNOSIS.pdf
PRENATAL TESTING AND DIAGNOSIS.pdfPRENATAL TESTING AND DIAGNOSIS.pdf
PRENATAL TESTING AND DIAGNOSIS.pdf
OM VERMA
 
REVIEW OF CELLULAR DIVISION MITOSIS AND MEIOSIS 2023.pdf
REVIEW OF CELLULAR DIVISION MITOSIS AND MEIOSIS 2023.pdfREVIEW OF CELLULAR DIVISION MITOSIS AND MEIOSIS 2023.pdf
REVIEW OF CELLULAR DIVISION MITOSIS AND MEIOSIS 2023.pdf
OM VERMA
 
sex linked inheritance error of transmission.pdf
sex linked inheritance error of transmission.pdfsex linked inheritance error of transmission.pdf
sex linked inheritance error of transmission.pdf
OM VERMA
 
The eugenics Movement.pdf
The eugenics Movement.pdfThe eugenics Movement.pdf
The eugenics Movement.pdf
OM VERMA
 

More from OM VERMA (20)

otalgia- JUN 2023 OM VERMA.pdf
otalgia- JUN 2023 OM VERMA.pdfotalgia- JUN 2023 OM VERMA.pdf
otalgia- JUN 2023 OM VERMA.pdf
 
POISIONING JUN 2023
POISIONING JUN 2023POISIONING JUN 2023
POISIONING JUN 2023
 
public relation.pdf
public relation.pdfpublic relation.pdf
public relation.pdf
 
PRENATAL TESTING AND DIAGNOSIS.pdf
PRENATAL TESTING AND DIAGNOSIS.pdfPRENATAL TESTING AND DIAGNOSIS.pdf
PRENATAL TESTING AND DIAGNOSIS.pdf
 
practical application of genetics in nursing OM VERMA 2022 slide.pdf
practical application of genetics in nursing  OM VERMA 2022 slide.pdfpractical application of genetics in nursing  OM VERMA 2022 slide.pdf
practical application of genetics in nursing OM VERMA 2022 slide.pdf
 
Neural tube defects and the role of folic acid in Lowering the Risk.pdf
Neural tube defects and the role of folic acid in Lowering the Risk.pdfNeural tube defects and the role of folic acid in Lowering the Risk.pdf
Neural tube defects and the role of folic acid in Lowering the Risk.pdf
 
MULTIPLE ALLOTS ( ALLELES ) AND BLOOD GROUPS OM VERMA 2023.pdf
MULTIPLE ALLOTS  ( ALLELES ) AND BLOOD GROUPS OM VERMA 2023.pdfMULTIPLE ALLOTS  ( ALLELES ) AND BLOOD GROUPS OM VERMA 2023.pdf
MULTIPLE ALLOTS ( ALLELES ) AND BLOOD GROUPS OM VERMA 2023.pdf
 
MENDALIAN THEORY OF INHERITANCE AND MULTIPLE BLOOD ALLOTS AND BLOOD GROUPS 20...
MENDALIAN THEORY OF INHERITANCE AND MULTIPLE BLOOD ALLOTS AND BLOOD GROUPS 20...MENDALIAN THEORY OF INHERITANCE AND MULTIPLE BLOOD ALLOTS AND BLOOD GROUPS 20...
MENDALIAN THEORY OF INHERITANCE AND MULTIPLE BLOOD ALLOTS AND BLOOD GROUPS 20...
 
Maternal prenatal and genetic influences on development of defect and disease...
Maternal prenatal and genetic influences on development of defect and disease...Maternal prenatal and genetic influences on development of defect and disease...
Maternal prenatal and genetic influences on development of defect and disease...
 
MATERNAL AGE,MATERNAL DRUG THERAPY PRENATAL TEST AND DIAGNOSIS.pdf
MATERNAL AGE,MATERNAL DRUG THERAPY PRENATAL TEST AND DIAGNOSIS.pdfMATERNAL AGE,MATERNAL DRUG THERAPY PRENATAL TEST AND DIAGNOSIS.pdf
MATERNAL AGE,MATERNAL DRUG THERAPY PRENATAL TEST AND DIAGNOSIS.pdf
 
infertility.pdf
infertility.pdfinfertility.pdf
infertility.pdf
 
Inborn Errors of Metablism.pdf
Inborn Errors of Metablism.pdfInborn Errors of Metablism.pdf
Inborn Errors of Metablism.pdf
 
Huntington Disease and Mental illness.pdf
Huntington Disease and Mental illness.pdfHuntington Disease and Mental illness.pdf
Huntington Disease and Mental illness.pdf
 
Hematological Disorders.pdf
Hematological Disorders.pdfHematological Disorders.pdf
Hematological Disorders.pdf
 
genetic testing inneanates and childern.pdf
genetic testing inneanates and childern.pdfgenetic testing inneanates and childern.pdf
genetic testing inneanates and childern.pdf
 
HUMAN GENOME PROJECT AND GENE THERAPY.pdf
HUMAN GENOME PROJECT AND GENE THERAPY.pdfHUMAN GENOME PROJECT AND GENE THERAPY.pdf
HUMAN GENOME PROJECT AND GENE THERAPY.pdf
 
PRENATAL TESTING AND DIAGNOSIS.pdf
PRENATAL TESTING AND DIAGNOSIS.pdfPRENATAL TESTING AND DIAGNOSIS.pdf
PRENATAL TESTING AND DIAGNOSIS.pdf
 
REVIEW OF CELLULAR DIVISION MITOSIS AND MEIOSIS 2023.pdf
REVIEW OF CELLULAR DIVISION MITOSIS AND MEIOSIS 2023.pdfREVIEW OF CELLULAR DIVISION MITOSIS AND MEIOSIS 2023.pdf
REVIEW OF CELLULAR DIVISION MITOSIS AND MEIOSIS 2023.pdf
 
sex linked inheritance error of transmission.pdf
sex linked inheritance error of transmission.pdfsex linked inheritance error of transmission.pdf
sex linked inheritance error of transmission.pdf
 
The eugenics Movement.pdf
The eugenics Movement.pdfThe eugenics Movement.pdf
The eugenics Movement.pdf
 

Recently uploaded

India Clinical Trials Market: Industry Size and Growth Trends [2030] Analyzed...
India Clinical Trials Market: Industry Size and Growth Trends [2030] Analyzed...India Clinical Trials Market: Industry Size and Growth Trends [2030] Analyzed...
India Clinical Trials Market: Industry Size and Growth Trends [2030] Analyzed...
Kumar Satyam
 
CANCER CANCER CANCER CANCER CANCER CANCER
CANCER  CANCER  CANCER  CANCER  CANCER CANCERCANCER  CANCER  CANCER  CANCER  CANCER CANCER
CANCER CANCER CANCER CANCER CANCER CANCER
KRISTELLEGAMBOA2
 
Telehealth Psychology Building Trust with Clients.pptx
Telehealth Psychology Building Trust with Clients.pptxTelehealth Psychology Building Trust with Clients.pptx
Telehealth Psychology Building Trust with Clients.pptx
The Harvest Clinic
 
HEAT WAVE presented by priya bhojwani..pptx
HEAT WAVE presented by priya bhojwani..pptxHEAT WAVE presented by priya bhojwani..pptx
HEAT WAVE presented by priya bhojwani..pptx
priyabhojwani1200
 
GENERAL PHARMACOLOGY - INTRODUCTION DENTAL.ppt
GENERAL PHARMACOLOGY - INTRODUCTION DENTAL.pptGENERAL PHARMACOLOGY - INTRODUCTION DENTAL.ppt
GENERAL PHARMACOLOGY - INTRODUCTION DENTAL.ppt
Mangaiarkkarasi
 
Navigating Healthcare with Telemedicine
Navigating Healthcare with  TelemedicineNavigating Healthcare with  Telemedicine
Navigating Healthcare with Telemedicine
Iris Thiele Isip-Tan
 
Navigating Women's Health: Understanding Prenatal Care and Beyond
Navigating Women's Health: Understanding Prenatal Care and BeyondNavigating Women's Health: Understanding Prenatal Care and Beyond
Navigating Women's Health: Understanding Prenatal Care and Beyond
Aboud Health Group
 
Antibiotic Stewardship by Anushri Srivastava.pptx
Antibiotic Stewardship by Anushri Srivastava.pptxAntibiotic Stewardship by Anushri Srivastava.pptx
Antibiotic Stewardship by Anushri Srivastava.pptx
AnushriSrivastav
 
Navigating the Health Insurance Market_ Understanding Trends and Options.pdf
Navigating the Health Insurance Market_ Understanding Trends and Options.pdfNavigating the Health Insurance Market_ Understanding Trends and Options.pdf
Navigating the Health Insurance Market_ Understanding Trends and Options.pdf
Enterprise Wired
 
CHAPTER 1 SEMESTER V PREVENTIVE-PEDIATRICS.pdf
CHAPTER 1 SEMESTER V PREVENTIVE-PEDIATRICS.pdfCHAPTER 1 SEMESTER V PREVENTIVE-PEDIATRICS.pdf
CHAPTER 1 SEMESTER V PREVENTIVE-PEDIATRICS.pdf
Sachin Sharma
 
Medical Technology Tackles New Health Care Demand - Research Report - March 2...
Medical Technology Tackles New Health Care Demand - Research Report - March 2...Medical Technology Tackles New Health Care Demand - Research Report - March 2...
Medical Technology Tackles New Health Care Demand - Research Report - March 2...
pchutichetpong
 
💘Ludhiana ℂall Girls 📞]][89011★83002][[ 📱 ❤ESCORTS service in Ludhiana💃💦Ludhi...
💘Ludhiana ℂall Girls 📞]][89011★83002][[ 📱 ❤ESCORTS service in Ludhiana💃💦Ludhi...💘Ludhiana ℂall Girls 📞]][89011★83002][[ 📱 ❤ESCORTS service in Ludhiana💃💦Ludhi...
💘Ludhiana ℂall Girls 📞]][89011★83002][[ 📱 ❤ESCORTS service in Ludhiana💃💦Ludhi...
ranishasharma67
 
What Are Homeopathic Treatments for Migraines.pdf
What Are Homeopathic Treatments for Migraines.pdfWhat Are Homeopathic Treatments for Migraines.pdf
What Are Homeopathic Treatments for Migraines.pdf
Dharma Homoeopathy
 
Immunity to Veterinary parasitic infections power point presentation
Immunity to Veterinary parasitic infections power point presentationImmunity to Veterinary parasitic infections power point presentation
Immunity to Veterinary parasitic infections power point presentation
BeshedaWedajo
 
Anatomy and Physiology Chapter-16_Digestive-System.pptx
Anatomy and Physiology Chapter-16_Digestive-System.pptxAnatomy and Physiology Chapter-16_Digestive-System.pptx
Anatomy and Physiology Chapter-16_Digestive-System.pptx
shanicedivinagracia2
 
Haridwar ❤CALL Girls 🔝 89011★83002 🔝 ❤ℂall Girls IN Haridwar ESCORT SERVICE❤
Haridwar ❤CALL Girls 🔝 89011★83002 🔝 ❤ℂall Girls IN Haridwar ESCORT SERVICE❤Haridwar ❤CALL Girls 🔝 89011★83002 🔝 ❤ℂall Girls IN Haridwar ESCORT SERVICE❤
Haridwar ❤CALL Girls 🔝 89011★83002 🔝 ❤ℂall Girls IN Haridwar ESCORT SERVICE❤
ranishasharma67
 
GURGAON Call Girls ❤8901183002❤ #ℂALL# #gIRLS# In GURGAON ₹,2500 Cash Payment...
GURGAON Call Girls ❤8901183002❤ #ℂALL# #gIRLS# In GURGAON ₹,2500 Cash Payment...GURGAON Call Girls ❤8901183002❤ #ℂALL# #gIRLS# In GURGAON ₹,2500 Cash Payment...
GURGAON Call Girls ❤8901183002❤ #ℂALL# #gIRLS# In GURGAON ₹,2500 Cash Payment...
ranishasharma67
 
Navigating Challenges: Mental Health, Legislation, and the Prison System in B...
Navigating Challenges: Mental Health, Legislation, and the Prison System in B...Navigating Challenges: Mental Health, Legislation, and the Prison System in B...
Navigating Challenges: Mental Health, Legislation, and the Prison System in B...
Guillermo Rivera
 
Contact Now 89011**83002 Dehradun ℂall Girls By Full Service ℂall Girl In De...
Contact Now  89011**83002 Dehradun ℂall Girls By Full Service ℂall Girl In De...Contact Now  89011**83002 Dehradun ℂall Girls By Full Service ℂall Girl In De...
Contact Now 89011**83002 Dehradun ℂall Girls By Full Service ℂall Girl In De...
aunty1x2
 
Artificial Intelligence to Optimize Cardiovascular Therapy
Artificial Intelligence to Optimize Cardiovascular TherapyArtificial Intelligence to Optimize Cardiovascular Therapy
Artificial Intelligence to Optimize Cardiovascular Therapy
Iris Thiele Isip-Tan
 

Recently uploaded (20)

India Clinical Trials Market: Industry Size and Growth Trends [2030] Analyzed...
India Clinical Trials Market: Industry Size and Growth Trends [2030] Analyzed...India Clinical Trials Market: Industry Size and Growth Trends [2030] Analyzed...
India Clinical Trials Market: Industry Size and Growth Trends [2030] Analyzed...
 
CANCER CANCER CANCER CANCER CANCER CANCER
CANCER  CANCER  CANCER  CANCER  CANCER CANCERCANCER  CANCER  CANCER  CANCER  CANCER CANCER
CANCER CANCER CANCER CANCER CANCER CANCER
 
Telehealth Psychology Building Trust with Clients.pptx
Telehealth Psychology Building Trust with Clients.pptxTelehealth Psychology Building Trust with Clients.pptx
Telehealth Psychology Building Trust with Clients.pptx
 
HEAT WAVE presented by priya bhojwani..pptx
HEAT WAVE presented by priya bhojwani..pptxHEAT WAVE presented by priya bhojwani..pptx
HEAT WAVE presented by priya bhojwani..pptx
 
GENERAL PHARMACOLOGY - INTRODUCTION DENTAL.ppt
GENERAL PHARMACOLOGY - INTRODUCTION DENTAL.pptGENERAL PHARMACOLOGY - INTRODUCTION DENTAL.ppt
GENERAL PHARMACOLOGY - INTRODUCTION DENTAL.ppt
 
Navigating Healthcare with Telemedicine
Navigating Healthcare with  TelemedicineNavigating Healthcare with  Telemedicine
Navigating Healthcare with Telemedicine
 
Navigating Women's Health: Understanding Prenatal Care and Beyond
Navigating Women's Health: Understanding Prenatal Care and BeyondNavigating Women's Health: Understanding Prenatal Care and Beyond
Navigating Women's Health: Understanding Prenatal Care and Beyond
 
Antibiotic Stewardship by Anushri Srivastava.pptx
Antibiotic Stewardship by Anushri Srivastava.pptxAntibiotic Stewardship by Anushri Srivastava.pptx
Antibiotic Stewardship by Anushri Srivastava.pptx
 
Navigating the Health Insurance Market_ Understanding Trends and Options.pdf
Navigating the Health Insurance Market_ Understanding Trends and Options.pdfNavigating the Health Insurance Market_ Understanding Trends and Options.pdf
Navigating the Health Insurance Market_ Understanding Trends and Options.pdf
 
CHAPTER 1 SEMESTER V PREVENTIVE-PEDIATRICS.pdf
CHAPTER 1 SEMESTER V PREVENTIVE-PEDIATRICS.pdfCHAPTER 1 SEMESTER V PREVENTIVE-PEDIATRICS.pdf
CHAPTER 1 SEMESTER V PREVENTIVE-PEDIATRICS.pdf
 
Medical Technology Tackles New Health Care Demand - Research Report - March 2...
Medical Technology Tackles New Health Care Demand - Research Report - March 2...Medical Technology Tackles New Health Care Demand - Research Report - March 2...
Medical Technology Tackles New Health Care Demand - Research Report - March 2...
 
💘Ludhiana ℂall Girls 📞]][89011★83002][[ 📱 ❤ESCORTS service in Ludhiana💃💦Ludhi...
💘Ludhiana ℂall Girls 📞]][89011★83002][[ 📱 ❤ESCORTS service in Ludhiana💃💦Ludhi...💘Ludhiana ℂall Girls 📞]][89011★83002][[ 📱 ❤ESCORTS service in Ludhiana💃💦Ludhi...
💘Ludhiana ℂall Girls 📞]][89011★83002][[ 📱 ❤ESCORTS service in Ludhiana💃💦Ludhi...
 
What Are Homeopathic Treatments for Migraines.pdf
What Are Homeopathic Treatments for Migraines.pdfWhat Are Homeopathic Treatments for Migraines.pdf
What Are Homeopathic Treatments for Migraines.pdf
 
Immunity to Veterinary parasitic infections power point presentation
Immunity to Veterinary parasitic infections power point presentationImmunity to Veterinary parasitic infections power point presentation
Immunity to Veterinary parasitic infections power point presentation
 
Anatomy and Physiology Chapter-16_Digestive-System.pptx
Anatomy and Physiology Chapter-16_Digestive-System.pptxAnatomy and Physiology Chapter-16_Digestive-System.pptx
Anatomy and Physiology Chapter-16_Digestive-System.pptx
 
Haridwar ❤CALL Girls 🔝 89011★83002 🔝 ❤ℂall Girls IN Haridwar ESCORT SERVICE❤
Haridwar ❤CALL Girls 🔝 89011★83002 🔝 ❤ℂall Girls IN Haridwar ESCORT SERVICE❤Haridwar ❤CALL Girls 🔝 89011★83002 🔝 ❤ℂall Girls IN Haridwar ESCORT SERVICE❤
Haridwar ❤CALL Girls 🔝 89011★83002 🔝 ❤ℂall Girls IN Haridwar ESCORT SERVICE❤
 
GURGAON Call Girls ❤8901183002❤ #ℂALL# #gIRLS# In GURGAON ₹,2500 Cash Payment...
GURGAON Call Girls ❤8901183002❤ #ℂALL# #gIRLS# In GURGAON ₹,2500 Cash Payment...GURGAON Call Girls ❤8901183002❤ #ℂALL# #gIRLS# In GURGAON ₹,2500 Cash Payment...
GURGAON Call Girls ❤8901183002❤ #ℂALL# #gIRLS# In GURGAON ₹,2500 Cash Payment...
 
Navigating Challenges: Mental Health, Legislation, and the Prison System in B...
Navigating Challenges: Mental Health, Legislation, and the Prison System in B...Navigating Challenges: Mental Health, Legislation, and the Prison System in B...
Navigating Challenges: Mental Health, Legislation, and the Prison System in B...
 
Contact Now 89011**83002 Dehradun ℂall Girls By Full Service ℂall Girl In De...
Contact Now  89011**83002 Dehradun ℂall Girls By Full Service ℂall Girl In De...Contact Now  89011**83002 Dehradun ℂall Girls By Full Service ℂall Girl In De...
Contact Now 89011**83002 Dehradun ℂall Girls By Full Service ℂall Girl In De...
 
Artificial Intelligence to Optimize Cardiovascular Therapy
Artificial Intelligence to Optimize Cardiovascular TherapyArtificial Intelligence to Optimize Cardiovascular Therapy
Artificial Intelligence to Optimize Cardiovascular Therapy
 

Slide for raynaud's disease

  • 1. RELIANCE INSTITUTE OF NURSING LIMTARA DHAMTARI (C.G) TOPIC - RAYNAUD’S DISEASE • PRESENTED BY- • OM VERMA • ASSISTANT PROFESSOR
  • 2.
  • 3. Raynaud’s disease Raynaud’s phenomenon is a form of intermittent arteriolar vasoconstriction that results in coldness, pain & pallor of the fingertips or toes. There are 2 forms of this disorders :- 1. Primary or idiopathic Raynaud’s disease 2. Secondary Raynaud’s syndrome
  • 4. Definition “Raynaud's phenomenon (RP) is a condition resulting in a particular series of discolorations of the fingers and/or the toes after exposure to changes in temp.(cold or hot) or emotional events. Skin discoloration occurs b’coz an abnormal spasm of the blood vessels causes a diminished blood supply to the local tissues.” according to luck man.s
  • 5. According to joyce M black The Raynaud’s phenomenon is used to refer to localized, intermittent episodes of vasoconstriction of small arteries of the feet and hands that cause color and temperature changes
  • 6. According to lippin cott • It is a recurrent vasospasm of the fingers and toes and usually occurs in response to stress or cold exposure
  • 7. Incidence Raynaud’s disease is most common in women between 16 & 40 yrs. Of age & it occurs more frequently in cold climates & during the winter.
  • 8. • CLASSIFICATION • • Primary • occurrence of the vasospasm alone, with no association with another illness • • Secondary • secondary to other conditions, most commonly an autoimmune disease • eg- SLE, rhematoid arthrits
  • 9. Etiology 1) Primary Raynaud’s disease :-(symptoms are idiopathic) Hereditary Smoking worsens frequency and intensity of attacks & there is a hormonal component. Caffeine 2) Secondary Raynaud’s (Syndrome) :- Connective tissue disorders Eating disorders Obstructive disorders Drugs Occupation Others
  • 10. • Working with vibrating machinery - the fingers may go into spasm. This is due to an intermittent lack of blood supply to the fingers. • o Emotional distress • o Exposure to the cold • • Exposure to chemicals such as PVC, Silica. • • Smoking • • Autoimmune disease
  • 11. Risk factors 1) The risk factors for primary Raynaud's include :- Gender,Age,Family history & Living in a cold climate 2) The risk factors for secondary Raynaud's include :-  Age  Certain diseases and conditions  Injuries to the hands or feet  Exposure to certain workplace chemicals  Repetitive actions with the hands  Certain medicines  Smoking  Living in a cold climate
  • 12.
  • 13. Clinical manifestation 1. Intermittent arteriolar vasoconstriction resulting in coldness, pain, pallor. 2. Involvement of the fingers appears to be asymmetric; thumbs are less often involved. 3. Characteristic color changes: white-blue-red. a) White- blanching, dead-white appearance if spasm is severe b) Blue - cyanotic,because of pooling of deoxygenated blood during vasospasm. c) Red – because of oxygenated blood returns to the digits after the vasospasm stops. 4. Occasionally,ulceration of the fingertips. 5. Numb, prickly feeling or stinging pain upon warming or relief of stress.
  • 14. • Signs and Symptoms • • The attacks can affect the fingers and toes, and rarely the nose, ears,or lips. • • The affected body parts will usually have two or more of the following changes: • • Look pale due to lack of blood flow • • Look bluish due to a lack of oxygen • • Feel numb, cold, or painful • • Redden as blood returns to the affected area
  • 15. • Patients often describe 3 phases of change – • • initial white (vasoconstriction), • • followed by blue (cyanosis), • • then red (rapid blood reflow
  • 16. Diagnostic evaluation 1. History taking 2. Physical examination 3. Cold Stimulation Test 4. Nail-fold Capillaroscopy 5. Digital artery pressure 6. Doppler ultrasound 7. Complete blood count 8. Blood test for urea & electrolytes 9. Thyroid function tests 10.An auto-antibody screen tests
  • 17. • Diagnosis • • History collection • Obtain a history of injury or frostbite • occupational history eg- jackhammers • Industrial exposure to polyvinyl chloride • Autoimmune disorders • • Physical examination • observe the colur of digits, ulcers • Examine nailfold capillaries under magnification help • diagnose underlying autoimmune disorders
  • 18. • Laboratory investigation • Complete blood count • ESR • Antinuclear antibody - May be positive in autoimmune disorders and should be obtained in patients with features of these disorders. • Rheumatoid factor - May be elevated in • rheumatoid arthritis, other autoimmune disorders
  • 19. • History taking :-Clinical symptoms must last atleast 2 yrs. To confirm the diagnosis.& Ask about the risk factors of the disease. • Physical examination :- Check the finger & toes for blood circulation.
  • 20. • Cold Stimulation Test :-A cold stimulation test can be used to trigger Raynaud's symptoms.For this test,a small device that measures temperature is taped to fingers.hands are then exposed to cold— they're usually briefly put into ice water.hands are then removed from the cold & the device measures how quickly fingers return to their normal temperature.If you have Raynaud's,it may take more than 20 minutes for fingers to return to their normal temperature.
  • 21. • Nail-fold Capillaroscopy :-For this test,doctor puts a drop of oil at the base of fingernail.He or she then looks at fingernail under a microscope.If doctor sees abnormal arteries,it may mean you have a disease linked to Raynaud's. • Digital artery pressure :- pressures are measured in the arteries of the fingers before and after the hands have been cooled. A decrease of at least 15 mmHg is diagnostic (positive). • Doppler ultrasound :-to assess blood flow.
  • 22. • Complete blood count :- this can reveal a normocytic anemia suggesting the anemia or renal failure
  • 23. • Blood test for urea and electrolytes:- this can reveal renal impairment. • Thyroid function tests :- this can reveal hypothyroidism. • An auto-antibody screentests:- for rheumatoid factor,Erythrocyte sedimentation rate and C-reactive protein,which may reveal specific causative illnesses or a generalised inflammatory process.
  • 24. • Medical Management • • Avoiding the particular stimuli (eg, cold, tobacco) • that provoke vasoconstriction • • Calcium channel blockers • eg- Nifidipine • 30-120 mg of the extended-release • formulation taken once daily • • Topical nitroglycerin (1% or 2%)
  • 25. • Medical management :- • Avoiding the particular stimuli such as cold &tobacco,that provoke vasoconstriction is a primary factor in controlling Raynaud's phenomenon. • Longer acting calcium channel blocker such as Nifedipine, Amlodipine may be used to prevent vasospasm. • Antiplatelet agents such as Aspirin or Dipyridamole (persantine) may be given to prevent total occlusion. • Sympathectomy (interrupting the sympathetic nerves by removing the sympathetic ganglia or dividing their branches) such as Reserpine (serpasil),Guanethidine or Prazosin may be helpful. •
  • 26. • Nursing Management • • The client is encouraged to avoid exposure to cold. • • Avoid repetitive hand movements and stressful situations. • • Quit smoking and avoids secondary smoke as nicotine is potent vasoconstrictor. • • Stress management techniques ex. biofeedback • • Assist in alleviating some distress from the condition
  • 27. • Complication :- • Atrophy of skin & muscles • Ulceration • Gangrene
  • 28. Medical management 1. Avoiding particular stimuli i.e. cold & tobacco 2. Calcium channel blocker such as Nifedipine, Amlodipine may be used 3. Antiplatelet agents such as Aspirin may be used. 4. Sympathectomy may be helpful.
  • 29. Alternative & experimental approaches 1. The Ayurvedic oil preparation Mahanarayan Oil has been used very successfully in many cases as a vasodilater when applied daily to affected areas. 2. Two separate gels combined on the fingertip increased blood flow in the fingertips by about three times.One gel contained 5% sodium nitrite and the other contained 5% ascorbic acid.The milliliter of combined gel covered an area of 3 cm².The gel was wiped off after a few seconds. 3. Fish oil supplements which contain long- chain omega-3 fatty acids may help to control symptoms of primary Raynaud's.
  • 30. Nursing management 1. Minimizing Sensory Alteration 2. Relieving Pain 3. Patient Education and Health Maintenance