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NUTRACEUTICALS – LET FOOD
BE YOUR MEDICINE
 Broccoli
 Green Tea & Herbal tea
 Flax seeds
 Black cohosh
 Turmeric
1
Prepared by
Zulie Shingala
Guide-Mr. Bhavik Chauhan
Assistant Professor
Faculty of Pharmacy,MSU.
BROCCOLI
• Broccoli is edible green plant in the cabbage family.
• Biological source is Brassica oleraceae
• Belonging to the family Cruciferae/Brassicaceae.
• Large flowering head and stalk is eaten as a vegetable.
• Broccoli resembles Cauliflower, which is different cultivar
group of the same Brassica species.
2
CHEMICAL CONSTITUENTS
• Broccoli is a particularly rich source of vitamin C and vitamin
K.
• Its characteristic sulphur containing glucosinolate compounds.
• Isothiocynate and sulforaphane .
• Good source of Folate(Folic acid).
• Provides potassium and fiber.
• Boiling of Broccoli is generally leads to reduced amount of
glucosinolate , isothiocynates and sulforaphane.
• Better to steaming , microwaving, or stir fying to preserve
these compounds.
3
HEALTH BENEFITS OF BROCCOLI
• 1) Vitamin K :-
• Essential for the functioning of many proteins involved in
blood clotting.
• 2) Folate :-
• Is necessary for the production and maintenanace of new
cells in the body.
• 3) Vitamin C :-
• Builds collagen, which forms body tissue and bone, and helps
cuts and wounds heal.
• Vitamin C is a powerful antioxidant and protects the body
from damagimg free radicals.
4
• 4) Fiber :-
• Broccoli high in fiber promote digestive health.
• A high fiber intake also help lower cholesterol.
• 5) Potassium :-
• A mineral and electrolyte that is essential for the function of nerves
and heart contraction.
• 6) Sulforaphane :-
• sulforaphane can inhibit the enzyme histone deacetylase (HDAC),
known to be involved in the progression of cancer cells.
• The ability to stop HDAC enzymes could make sulforaphane-
containing foods a potentially powerful part of cancer treatment in
the future.
5
6
GREEN TEA
• Green tea – a popular beverage in Japan made from leaves of
Camellia sinesis belongigng to the family Theaceae.
• Green tea originated in China , but its production and
manufacture has spread to many other countries in Asia.
• It is not fermented product but it is obtained by leaf
dessication (process of extreme drying).
• Leaves and buds of Camellia sinesis not undergone the
procedure of withering and oxidation ( procedure to make
black tea )
7
• Several varieties of green tea exist, which differ substantially
based on the variety of Camellia sinesis used, growing
conditions, production processing and time of harvest.
8
PREPARATION
• Steeping is the process of making green tea from leaves and
hot water.
• Tea being prepared by leaving the leaves in heated water to
release the flavour and nutrients.
• Generally using 2 gm of tea per 100 ml of warm water is same
as 1 teaspoon of green tea per a cup (150ml) of warm water.
• Steeping time is from 30 seconds to 3 minutes.
9
• Also can be prepared by infusion of prepared tea bags.
10
CHEMICAL CONSTITUENTS
• Poly phenols found in green tea includes –
I. Gallocatechin
II. Epigallocatechin
III. Catechin
IV. Epigallocatechin gallate (EGCG)
V. Gallocatechin gallate
VI. Epicatechin gallate
• Flavonoids-
I. Kaempferol,
II. Quercetin,
III. Myricetin
• And caffeine
11
HEALTH BENEFITS OF GREEN TEA
• Green tea was used in traditional Chinese and Indian
medicine to control bleeding and heal wounds,
• Aid digestion,
• Improve heart and mental health,
• Regulate body temperature.
• Recent studies have shown that it can potentially have
positive effects on weight loss.
12
1) Green tea and cancer prevention
• According to the National Cancer Institute, the polyphenols in tea
have been shown to decrease tumor growth in laboratory and
animal studies.
• It protect against damage caused by UV radiation.
• Green tea shown the positive impacts on the following type of
cancer-
 Breast
 Skin
 Ovarian
• High level of polyphenols in tea that helps to kill cancerous cells and
stop them from growing.
• But the exact mechanism by which tea interacts with cancerous
cells is unknown.
13
• Lowers cholesterol:-
• Cosuming green tea, either as abeverage or in capsule form is
linked to significant reductions in total and LDL cholesterol.
• It has no effects on HDL cholesterol which is good cholesterol.
• Antioxidants:-
• Polyphenols and flavonoids present in green tea acts as
antioxidants.
• That prevents cell damage.
• And reduce the formation of free radicals.
14
• Skin benefits of green tea :-
• Epigallocatechin and catechin present in green tea is 200
times more powerful than Vitamin E.
• It acts as a natural anti-ageing ingredient, preventing wrinkles.
• Effect on liver :-
• Liver is one of the key metabolic organ involved in the
synthesis and degradation of key biological molecules –
carbohydrates, protein and lipids.
• Green tea intake is associated with decreased risk of
HCC(hepatocellular carcinoma), fatty liver disease and
hepatitis.
• Long term consumption of green tea catechins could be
beneficial against high fat diet-induced obesity and type Ⅱ
diabetes.
15
HERBAL TEA
• Herbal tea called tisanes are beverages can be made with
fresh or dried edible flowers, fruit, leaves, seeds or roots.
• Unlike most other forms of tea, herbal teas do not contain
caffeine.
• Most herbal teas may consist of one main herbal ingredient
or a blend of herbal ingredients, intended to bring about a
specific purpose such as relaxation, rejuvenation and relief.
• Made by pouring boiling water over the plant part and
letting theme steep for few a minutes, generally for 1 to 3
minutes and then strained, sweetened(with honey) if
required and served.
• Many companies produce herbal tea bags for such
infusions.
16
Varieties of herbal tea can be made from any edible plant
material, below is a list of those commonly used herbs to make
herbal tea
• Anise tea- either seeds or leaves are used.
• Bael fruit tea
• Cinnamon tea
• CCF or CFC tea- contains fennel, cumin and coriander
• Citrus peel- lemon or orange peel
• Ginger tea
• Hibiscus – it is also consumed in Chinese and Ayurvedic
medicine
• Lemon grass tea
• Moringa tea
17
EXAMPLES
• Coconut
• apple
• Ginger
• Cinnamon
• lemon
• Cardamom
• Black pepper
• Tulsi
• Lemon grass
• Mint leaves
• Rose petals
• Fennel, cumin, ajma and coriander (whole seeds or
powder).
• Honey as sweetner
18
Each ingredients tha used in herbal tea having a
different use and purpose.
Some common ones include-
Cinnamon- is calming and helps to support
healthy circulation and digestion.
Ginger root- is excellent for improving circulation
and is one of the best herbs for improving
digestion, lung congestion and arthritis.
Parsley- is a diuretic and helps with kidney
function.
Peppermint- is good for stress relief.
Also helps with stomachs and digestive issues and
helps to freshen the breath.
19
 Ginseng- stimulates vitality and helps the body stay
healthy. It is the best immunomodulator.
Fennel, coriander and cumin-
Helps to improve digestion and acts as purgative.
Honey- added to the tea as sweetner. Because it
has more beneficial than sugar.
Lemon- it acts as antioxidant. Helps to aid
digestion and weight loss.
it is rich source of Vitamin C.
20
FLAX SEEDS
• It is the dried ripe seeds obtained from linum
usitatissimum.
• Family- Linaceae
• Canada is the largest producer and exporter of
flaxseeds which is about 40% of the world supply.
• It is also cultivated in US, Russia and India.
• Generally flaxseed is cultivated for the oil but many
medicinal properties are found to be associated with
flaxseeds and its constituents.
• Flaxseeds has been recorded as one of the six plant
materials as cancer preventive foods.
21
CHEMICAL CONSTITUENTS
• Flaxseed is an abudant source of gamma-linolenic acid (GLA).
• Alpha linolenic acid (ALA)
• Viscous fibre components – mucilage(6%)
• Lignan – secoisolariciresinol diglycoside(SDG)
• proteins.
22
HEALTH BENEFITS OF FLAXSEED
• It inhibits the production of ecosanoids, alters the
production of several prostanoids.
• It Reduces blood pressure in hypertensive patients
• It lowers triglycerides and cholesterol
• Dietary ALA may retard tumour growth and plays
important role in metastatis.
• It is essential for optical neurological development of
human especially during fetal development.
23
• GLA - and its metabolites are effective in supression of
inflammation, in the treatment of diabetes neuropathy.
• Mucilage – play a role in reducing diabetes
• coronary heart disease risk
• preventing colon and rectal cancer.
• Act as hypolipidaemic.
• Flaxseed extract and purified lignans exhibit
antioxidant effect.
24
BLACK COHOSH
• Roots and rhizomes of black cohosh is generally used.
• It is obtained from Actaea racemosa
• syn. Cimicfuga racemosa
• Family is Ranunculaceae.
• It is native to eastern North America .
• The roots and rhizomes were used in traditional
medicine by native Americans.
• Its extract are manufactured as herbal medicines and
dietary supplements and recommended for safe and
effective use in treating menopause symptoms.
• Native Americans used black black cohosh to treat
gynecological disorders.
25
PHYTOCHEMICALS
• Polyphenols- isoferulic aid, salicylic acid .
• Estrogen like compounds(isoflavones)
• Cimigenol
• Formononetin
• cimipronidine
26
MEDICINAL USE OF BLACK COHOSH
• Based on current research , black cohosh is most likely to
relieve symptoms related to reduction or imbalances in the
hormone estrogen.
• It reduces leutinizing hormone levels which are thought to be
responsible for postmenopausal symptoms.
• It reduces following menopausal symptoms :-
• Hot flashes
• Sleep disturbances
• Mood changes
• Ringing in the ears
• Vertigo
27
TURMERIC
• It is the rhizomes of Curcuma longa
• Family- Zingiberaceae.
• Used as a spice all over the world.
• It used in traditional medicine in China and India.
• Has so many health benefits.
• Also used in cosmetics.
28
PHYTOCHEMICALS
• Turmeric contains diarylnheptanoid compounds. Having
oleoresin compounds.
• Consisting mainly curcumin,
• Desmethoxycurcumin,
• And bidismethoxycurcumin.
• yellow colour of turmeric is due to curcumin.
• Essential oil,
• Diatery fibers.
29
USE OF TURMERIC
• 1) Anti-inflammatory properties:-
• Oral administration of curcumin in instances of acute
inflammation was found to be as effective as cortisone or
phenylbutazone.
• It significantly reduce inflammatory swelling.
• Curcuminoids inhibits COX, phospholipases, leukotrienes,
prostaglandins, thromboxane and decrease prostaglandins
formation.
 Gastrointestinal disorders:-
 It is beneficial in prevention of variety of GI tract disorders,
including H. pylori infection, peptic ulcer and ulcerative colitis.
30
• 2) Antioxidant properties :-
• It has strong antioxidant property.
• Comparable to Vitamin C.
• 3) Hepatoprotective properties :-
• Curcumin administration decrease liver injury.
• It reduces fatty changes and necrosis induced by aflatoxin
production.
• 4)antidiabetic property:-
• Curcuminoids and sesquiterpenoids are acts as hypoglycemic.
• 5) Antimicrobial properties:-
• Turmeric extract and essential oil of Curcuma longa inhibit the
growth of a variety of bacteria and pathogenic fungi.
31
• 6) Antidepressant properties:-
• Turmeric has antidepressant properties mediated through
inhibition of monoamine oxidase A.
• It helps to relief in stress condition,
• Boosts cognitive abilities.
• 7) Cardiovascular diseases :-
• It has protective properties on the CVS include-
• Lowering cholesterol and triglyceride level,
• Inhibit platelet aggregation,
• It decrease cholesterol uptake in the intestines and increases
conversion of cholesterol to bile acids in the liver.
32
33
REFERENCE
• Pharmacognosy and pharmacobiotechnology, by Ashutosh
Kar, Second edition, new age publications.
• Textbook of pharmacognosy and phytochemistry, Biren Shah
& A.K. Seth.
• All the images are from www.google.com
• www.wikipedia.org
• www.researchgate.net
• www.healthline.com
• www.medicalnewstoday.com
• www.nutraceuticalsworld.com
34
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Nutraceuticals – let food be your medicine

  • 1. NUTRACEUTICALS – LET FOOD BE YOUR MEDICINE  Broccoli  Green Tea & Herbal tea  Flax seeds  Black cohosh  Turmeric 1 Prepared by Zulie Shingala Guide-Mr. Bhavik Chauhan Assistant Professor Faculty of Pharmacy,MSU.
  • 2. BROCCOLI • Broccoli is edible green plant in the cabbage family. • Biological source is Brassica oleraceae • Belonging to the family Cruciferae/Brassicaceae. • Large flowering head and stalk is eaten as a vegetable. • Broccoli resembles Cauliflower, which is different cultivar group of the same Brassica species. 2
  • 3. CHEMICAL CONSTITUENTS • Broccoli is a particularly rich source of vitamin C and vitamin K. • Its characteristic sulphur containing glucosinolate compounds. • Isothiocynate and sulforaphane . • Good source of Folate(Folic acid). • Provides potassium and fiber. • Boiling of Broccoli is generally leads to reduced amount of glucosinolate , isothiocynates and sulforaphane. • Better to steaming , microwaving, or stir fying to preserve these compounds. 3
  • 4. HEALTH BENEFITS OF BROCCOLI • 1) Vitamin K :- • Essential for the functioning of many proteins involved in blood clotting. • 2) Folate :- • Is necessary for the production and maintenanace of new cells in the body. • 3) Vitamin C :- • Builds collagen, which forms body tissue and bone, and helps cuts and wounds heal. • Vitamin C is a powerful antioxidant and protects the body from damagimg free radicals. 4
  • 5. • 4) Fiber :- • Broccoli high in fiber promote digestive health. • A high fiber intake also help lower cholesterol. • 5) Potassium :- • A mineral and electrolyte that is essential for the function of nerves and heart contraction. • 6) Sulforaphane :- • sulforaphane can inhibit the enzyme histone deacetylase (HDAC), known to be involved in the progression of cancer cells. • The ability to stop HDAC enzymes could make sulforaphane- containing foods a potentially powerful part of cancer treatment in the future. 5
  • 6. 6
  • 7. GREEN TEA • Green tea – a popular beverage in Japan made from leaves of Camellia sinesis belongigng to the family Theaceae. • Green tea originated in China , but its production and manufacture has spread to many other countries in Asia. • It is not fermented product but it is obtained by leaf dessication (process of extreme drying). • Leaves and buds of Camellia sinesis not undergone the procedure of withering and oxidation ( procedure to make black tea ) 7
  • 8. • Several varieties of green tea exist, which differ substantially based on the variety of Camellia sinesis used, growing conditions, production processing and time of harvest. 8
  • 9. PREPARATION • Steeping is the process of making green tea from leaves and hot water. • Tea being prepared by leaving the leaves in heated water to release the flavour and nutrients. • Generally using 2 gm of tea per 100 ml of warm water is same as 1 teaspoon of green tea per a cup (150ml) of warm water. • Steeping time is from 30 seconds to 3 minutes. 9
  • 10. • Also can be prepared by infusion of prepared tea bags. 10
  • 11. CHEMICAL CONSTITUENTS • Poly phenols found in green tea includes – I. Gallocatechin II. Epigallocatechin III. Catechin IV. Epigallocatechin gallate (EGCG) V. Gallocatechin gallate VI. Epicatechin gallate • Flavonoids- I. Kaempferol, II. Quercetin, III. Myricetin • And caffeine 11
  • 12. HEALTH BENEFITS OF GREEN TEA • Green tea was used in traditional Chinese and Indian medicine to control bleeding and heal wounds, • Aid digestion, • Improve heart and mental health, • Regulate body temperature. • Recent studies have shown that it can potentially have positive effects on weight loss. 12
  • 13. 1) Green tea and cancer prevention • According to the National Cancer Institute, the polyphenols in tea have been shown to decrease tumor growth in laboratory and animal studies. • It protect against damage caused by UV radiation. • Green tea shown the positive impacts on the following type of cancer-  Breast  Skin  Ovarian • High level of polyphenols in tea that helps to kill cancerous cells and stop them from growing. • But the exact mechanism by which tea interacts with cancerous cells is unknown. 13
  • 14. • Lowers cholesterol:- • Cosuming green tea, either as abeverage or in capsule form is linked to significant reductions in total and LDL cholesterol. • It has no effects on HDL cholesterol which is good cholesterol. • Antioxidants:- • Polyphenols and flavonoids present in green tea acts as antioxidants. • That prevents cell damage. • And reduce the formation of free radicals. 14
  • 15. • Skin benefits of green tea :- • Epigallocatechin and catechin present in green tea is 200 times more powerful than Vitamin E. • It acts as a natural anti-ageing ingredient, preventing wrinkles. • Effect on liver :- • Liver is one of the key metabolic organ involved in the synthesis and degradation of key biological molecules – carbohydrates, protein and lipids. • Green tea intake is associated with decreased risk of HCC(hepatocellular carcinoma), fatty liver disease and hepatitis. • Long term consumption of green tea catechins could be beneficial against high fat diet-induced obesity and type Ⅱ diabetes. 15
  • 16. HERBAL TEA • Herbal tea called tisanes are beverages can be made with fresh or dried edible flowers, fruit, leaves, seeds or roots. • Unlike most other forms of tea, herbal teas do not contain caffeine. • Most herbal teas may consist of one main herbal ingredient or a blend of herbal ingredients, intended to bring about a specific purpose such as relaxation, rejuvenation and relief. • Made by pouring boiling water over the plant part and letting theme steep for few a minutes, generally for 1 to 3 minutes and then strained, sweetened(with honey) if required and served. • Many companies produce herbal tea bags for such infusions. 16
  • 17. Varieties of herbal tea can be made from any edible plant material, below is a list of those commonly used herbs to make herbal tea • Anise tea- either seeds or leaves are used. • Bael fruit tea • Cinnamon tea • CCF or CFC tea- contains fennel, cumin and coriander • Citrus peel- lemon or orange peel • Ginger tea • Hibiscus – it is also consumed in Chinese and Ayurvedic medicine • Lemon grass tea • Moringa tea 17
  • 18. EXAMPLES • Coconut • apple • Ginger • Cinnamon • lemon • Cardamom • Black pepper • Tulsi • Lemon grass • Mint leaves • Rose petals • Fennel, cumin, ajma and coriander (whole seeds or powder). • Honey as sweetner 18
  • 19. Each ingredients tha used in herbal tea having a different use and purpose. Some common ones include- Cinnamon- is calming and helps to support healthy circulation and digestion. Ginger root- is excellent for improving circulation and is one of the best herbs for improving digestion, lung congestion and arthritis. Parsley- is a diuretic and helps with kidney function. Peppermint- is good for stress relief. Also helps with stomachs and digestive issues and helps to freshen the breath. 19
  • 20.  Ginseng- stimulates vitality and helps the body stay healthy. It is the best immunomodulator. Fennel, coriander and cumin- Helps to improve digestion and acts as purgative. Honey- added to the tea as sweetner. Because it has more beneficial than sugar. Lemon- it acts as antioxidant. Helps to aid digestion and weight loss. it is rich source of Vitamin C. 20
  • 21. FLAX SEEDS • It is the dried ripe seeds obtained from linum usitatissimum. • Family- Linaceae • Canada is the largest producer and exporter of flaxseeds which is about 40% of the world supply. • It is also cultivated in US, Russia and India. • Generally flaxseed is cultivated for the oil but many medicinal properties are found to be associated with flaxseeds and its constituents. • Flaxseeds has been recorded as one of the six plant materials as cancer preventive foods. 21
  • 22. CHEMICAL CONSTITUENTS • Flaxseed is an abudant source of gamma-linolenic acid (GLA). • Alpha linolenic acid (ALA) • Viscous fibre components – mucilage(6%) • Lignan – secoisolariciresinol diglycoside(SDG) • proteins. 22
  • 23. HEALTH BENEFITS OF FLAXSEED • It inhibits the production of ecosanoids, alters the production of several prostanoids. • It Reduces blood pressure in hypertensive patients • It lowers triglycerides and cholesterol • Dietary ALA may retard tumour growth and plays important role in metastatis. • It is essential for optical neurological development of human especially during fetal development. 23
  • 24. • GLA - and its metabolites are effective in supression of inflammation, in the treatment of diabetes neuropathy. • Mucilage – play a role in reducing diabetes • coronary heart disease risk • preventing colon and rectal cancer. • Act as hypolipidaemic. • Flaxseed extract and purified lignans exhibit antioxidant effect. 24
  • 25. BLACK COHOSH • Roots and rhizomes of black cohosh is generally used. • It is obtained from Actaea racemosa • syn. Cimicfuga racemosa • Family is Ranunculaceae. • It is native to eastern North America . • The roots and rhizomes were used in traditional medicine by native Americans. • Its extract are manufactured as herbal medicines and dietary supplements and recommended for safe and effective use in treating menopause symptoms. • Native Americans used black black cohosh to treat gynecological disorders. 25
  • 26. PHYTOCHEMICALS • Polyphenols- isoferulic aid, salicylic acid . • Estrogen like compounds(isoflavones) • Cimigenol • Formononetin • cimipronidine 26
  • 27. MEDICINAL USE OF BLACK COHOSH • Based on current research , black cohosh is most likely to relieve symptoms related to reduction or imbalances in the hormone estrogen. • It reduces leutinizing hormone levels which are thought to be responsible for postmenopausal symptoms. • It reduces following menopausal symptoms :- • Hot flashes • Sleep disturbances • Mood changes • Ringing in the ears • Vertigo 27
  • 28. TURMERIC • It is the rhizomes of Curcuma longa • Family- Zingiberaceae. • Used as a spice all over the world. • It used in traditional medicine in China and India. • Has so many health benefits. • Also used in cosmetics. 28
  • 29. PHYTOCHEMICALS • Turmeric contains diarylnheptanoid compounds. Having oleoresin compounds. • Consisting mainly curcumin, • Desmethoxycurcumin, • And bidismethoxycurcumin. • yellow colour of turmeric is due to curcumin. • Essential oil, • Diatery fibers. 29
  • 30. USE OF TURMERIC • 1) Anti-inflammatory properties:- • Oral administration of curcumin in instances of acute inflammation was found to be as effective as cortisone or phenylbutazone. • It significantly reduce inflammatory swelling. • Curcuminoids inhibits COX, phospholipases, leukotrienes, prostaglandins, thromboxane and decrease prostaglandins formation.  Gastrointestinal disorders:-  It is beneficial in prevention of variety of GI tract disorders, including H. pylori infection, peptic ulcer and ulcerative colitis. 30
  • 31. • 2) Antioxidant properties :- • It has strong antioxidant property. • Comparable to Vitamin C. • 3) Hepatoprotective properties :- • Curcumin administration decrease liver injury. • It reduces fatty changes and necrosis induced by aflatoxin production. • 4)antidiabetic property:- • Curcuminoids and sesquiterpenoids are acts as hypoglycemic. • 5) Antimicrobial properties:- • Turmeric extract and essential oil of Curcuma longa inhibit the growth of a variety of bacteria and pathogenic fungi. 31
  • 32. • 6) Antidepressant properties:- • Turmeric has antidepressant properties mediated through inhibition of monoamine oxidase A. • It helps to relief in stress condition, • Boosts cognitive abilities. • 7) Cardiovascular diseases :- • It has protective properties on the CVS include- • Lowering cholesterol and triglyceride level, • Inhibit platelet aggregation, • It decrease cholesterol uptake in the intestines and increases conversion of cholesterol to bile acids in the liver. 32
  • 33. 33
  • 34. REFERENCE • Pharmacognosy and pharmacobiotechnology, by Ashutosh Kar, Second edition, new age publications. • Textbook of pharmacognosy and phytochemistry, Biren Shah & A.K. Seth. • All the images are from www.google.com • www.wikipedia.org • www.researchgate.net • www.healthline.com • www.medicalnewstoday.com • www.nutraceuticalsworld.com 34
  • 35. 35