Lignans are phenyl propanoids dimer found in many plants, particularly in seeds like sesame seeds, linseed, sunflower seeds, pumkin seeds, etc. and they are having anti microbial, anti viral and anti fungal activity.
This document provides information on the isolation and analysis of several compounds:
1. Quinine is isolated from cinchona bark through extraction with benzene followed by crystallization. It is analyzed using thin layer chromatography.
2. Glycyrrhetinic acid is the active compound in liquorice root. It is isolated through chloroform extraction and acid hydrolysis, and analyzed with chemical tests and thin layer chromatography.
3. Rutin is isolated from eucalyptus leaves by boiling in water and recrystallization. It is analyzed using chemical tests and thin layer chromatography.
4. Podophyllotoxin, the active compound in mayapple, is extracted with methanol and benzene from
Industrial production,estimation and utilization of DiosgeninNadeemSiddiqui37
The document discusses diosgenin, a precursor used in pharmaceuticals like oral contraceptives. It is commonly extracted from Dioscorea zingiberensis tubers using acid hydrolysis. The document outlines methods to extract and isolate diosgenin from plant materials like seeds and hairy roots, such as refluxing with sulfuric acid and eluting with hexane. Analytical methods to analyze diosgenin are also presented, including thin layer chromatography using antimony trichloride as a detecting agent. Diosgenin is useful as it can be used in progesterone semi-synthesis and produces estrogenic activity.
Isolation Extraction Estimation of ArtemisininAFSATH
This document summarizes the extraction and quantification of artemisinin from the plant Artemisia annua. The plant material is extracted using solvents like methanol, hexane, and ethyl acetate. The extract is then partitioned and purified through chromatography. Artemisinin content is estimated using two methods - TLC densitometry and HPLC. Both methods involve developing a calibration curve to determine the concentration of artemisinin in the test samples. Artemisinin extracted from A. annua is used effectively to treat malaria and other diseases.
UNIT V - Study of biological source, chemical nature and uses of drugs of
natural origin containing the following drugs
(a) Plant Products:
Fibers - Cotton,
Ephedra contains amino alkaloids such as ephedrine, nor-ephedrine, and pseudo-ephedrine. It grows mainly in China, Pakistan, India, Australia, and parts of Europe at altitudes between 2500-3000m with annual rainfall under 50cm. The stems are collected after 4 years, dried, and stored away from light. Ephedra acts as a bronchodilator for treating asthma and hay fever due to its sympathomimetic effects.
Introduction to saponin glycosides, Saponin glycosides, Properties of saponin glycosides, Types of saponin glycosides, chemical tests of saponin glycosides
Rutin is a citrus flavonoid glycoside found in many plants that contributes to their antioxidant and antibacterial properties. It occurs as a yellow crystalline powder soluble in alkali but only slightly soluble in water. On hydrolysis, rutin yields quervetin, rhamnose and glucose. Rutin was extracted from plant seeds, leaves, and callus using Soxhlet extraction with ethanol, followed by separation using petroleum ether, chloroform and aqueous layers. Identification of the extracted rutin was confirmed using IR spectroscopy which showed peaks for alcoholic, phenolic, alkene, ether, and carbonyl functional groups. Rutin has various pharmacological functions as an antioxidant with antibacterial, anti-inflammatory and
Turmeric is obtained from the dried rhizomes of the plant Curcuma longa. It contains the yellow chemical curcumin, which makes up 50-60% of turmeric. Curcumin can be isolated from turmeric powder through extraction with alcohol or hexane followed by acetone. Curcumin is identified through chemical tests where it produces a crimson color with sulfuric acid or a reddish brown color with boric acid that turns greenish blue with alkali. Curcumin content can be analyzed using methods like HPLC, where it shows peaks at specific retention times when separated using a Nucleosil NH2 column with ethanol mobile phase and UV detection at 254nm.
This document provides information on the isolation and analysis of several compounds:
1. Quinine is isolated from cinchona bark through extraction with benzene followed by crystallization. It is analyzed using thin layer chromatography.
2. Glycyrrhetinic acid is the active compound in liquorice root. It is isolated through chloroform extraction and acid hydrolysis, and analyzed with chemical tests and thin layer chromatography.
3. Rutin is isolated from eucalyptus leaves by boiling in water and recrystallization. It is analyzed using chemical tests and thin layer chromatography.
4. Podophyllotoxin, the active compound in mayapple, is extracted with methanol and benzene from
Industrial production,estimation and utilization of DiosgeninNadeemSiddiqui37
The document discusses diosgenin, a precursor used in pharmaceuticals like oral contraceptives. It is commonly extracted from Dioscorea zingiberensis tubers using acid hydrolysis. The document outlines methods to extract and isolate diosgenin from plant materials like seeds and hairy roots, such as refluxing with sulfuric acid and eluting with hexane. Analytical methods to analyze diosgenin are also presented, including thin layer chromatography using antimony trichloride as a detecting agent. Diosgenin is useful as it can be used in progesterone semi-synthesis and produces estrogenic activity.
Isolation Extraction Estimation of ArtemisininAFSATH
This document summarizes the extraction and quantification of artemisinin from the plant Artemisia annua. The plant material is extracted using solvents like methanol, hexane, and ethyl acetate. The extract is then partitioned and purified through chromatography. Artemisinin content is estimated using two methods - TLC densitometry and HPLC. Both methods involve developing a calibration curve to determine the concentration of artemisinin in the test samples. Artemisinin extracted from A. annua is used effectively to treat malaria and other diseases.
UNIT V - Study of biological source, chemical nature and uses of drugs of
natural origin containing the following drugs
(a) Plant Products:
Fibers - Cotton,
Ephedra contains amino alkaloids such as ephedrine, nor-ephedrine, and pseudo-ephedrine. It grows mainly in China, Pakistan, India, Australia, and parts of Europe at altitudes between 2500-3000m with annual rainfall under 50cm. The stems are collected after 4 years, dried, and stored away from light. Ephedra acts as a bronchodilator for treating asthma and hay fever due to its sympathomimetic effects.
Introduction to saponin glycosides, Saponin glycosides, Properties of saponin glycosides, Types of saponin glycosides, chemical tests of saponin glycosides
Rutin is a citrus flavonoid glycoside found in many plants that contributes to their antioxidant and antibacterial properties. It occurs as a yellow crystalline powder soluble in alkali but only slightly soluble in water. On hydrolysis, rutin yields quervetin, rhamnose and glucose. Rutin was extracted from plant seeds, leaves, and callus using Soxhlet extraction with ethanol, followed by separation using petroleum ether, chloroform and aqueous layers. Identification of the extracted rutin was confirmed using IR spectroscopy which showed peaks for alcoholic, phenolic, alkene, ether, and carbonyl functional groups. Rutin has various pharmacological functions as an antioxidant with antibacterial, anti-inflammatory and
Turmeric is obtained from the dried rhizomes of the plant Curcuma longa. It contains the yellow chemical curcumin, which makes up 50-60% of turmeric. Curcumin can be isolated from turmeric powder through extraction with alcohol or hexane followed by acetone. Curcumin is identified through chemical tests where it produces a crimson color with sulfuric acid or a reddish brown color with boric acid that turns greenish blue with alkali. Curcumin content can be analyzed using methods like HPLC, where it shows peaks at specific retention times when separated using a Nucleosil NH2 column with ethanol mobile phase and UV detection at 254nm.
The document summarizes information about the plant Catharanthus roseus, commonly known as Vinca or Periwinkle. It is native to Madagascar but cultivated in other tropical and subtropical regions. The plant contains important anticancer alkaloids vinblastine and vincristine in its leaves and roots. Vinblastine is used to treat Hodgkin's disease while vincristine is used for childhood leukemia. The flowers may also be used as a gentle laxative or gargle.
Pharmacognosy OF LIQUORICE(Saponin Glycoside)ALOK SINGH
This document summarizes information about the plant liquorice (Glycyrrhiza glabra). It is grown in sub-Himalayan regions and parts of Europe. Microscopically, it exhibits cork layers, medullary rays, phloem fibers, xylem vessels and fibers, and parenchyma cells containing starch grains and calcium oxalate crystals. It contains saponin glycosides and glycyrrhetinic acid. Liquorice has demulcent, expectorant, and mineralocorticoid properties and is used in cough syrups, lozenges, and to mask bitter tastes in medicines. Its saponins aid absorption of some drugs. Adulterants include
ISOLATION AND ESTIMATION OF GLYCERRHIZIN AND PHYLLANTHINnaseefa
This document discusses the isolation and estimation of two phytoconstituents - glycerrhizin from liquorice root and phyllanthin from Phyllanthus amarus. It describes the biological sources, chemical constituents, isolation methods including acid precipitation, alcohol extraction and ammonia extraction for glycerrhizin. For phyllanthin, the isolation involves extraction with petroleum ether followed by column chromatography. Estimation methods discussed are TLC densitometry, colorimetric and HPLC methods for glycerrhizin and TLC and HPLC for identifying and estimating phyllanthin.
Volatile oils can be extracted through three main methods: distillation, solvent extraction, and mechanical expression. Distillation involves boiling or steaming plant material to separate the oils, while solvent extraction soaks plants in solvents like alcohol. Mechanical expression ruptures oil cells without heat, as used for citrus peels.
Gentian is a plant whose dried rhizome and roots are used as a bitter tonic. It contains several bitter glycosides such as gentiopicrin, which has an intensely bitter taste and is used to stimulate digestion. Gentian grows in central and southern Europe and Asia, and its rhizomes are harvested in autumn after 2-5 years of growth. Microscopically, transverse sections of gentian rhizome show a porous wood surrounded by parenchyma cells containing oil globules and calcium oxalate needles. Gentian is used as a stomachic to treat indigestion and other gastrointestinal issues.
Glycosides are organic compounds found in plants and animals that contain a sugar moiety bonded to a non-sugar aglycon portion. They are classified based on the chemical nature of the aglycon, the nature of the sugar moiety, and the type of linkage between the glycon and aglycon. Glycosides are isolated using the Stas-Otto method involving successive extraction with alcohol and precipitation with lead acetate. Cardiac glycosides contain steroidal aglycons and are isolated from plants like Nerium oleander through alcoholic extraction, precipitation, and partitioning between organic solvents. Anthraquinone glycosides are isolated through successive extraction of the plant material with organic solvents and purification by column
Chaulmoogra oil is a fixed oil obtained from seeds of various Hydnocarpus species found in Myanmar. It contains chaulmoogric acid and hydnoctic acid as major constituents. Chaulmoogra oil has bactericidal effects against Mycobacterium leprae and M. tuberculosis, making it useful in the treatment of leprosy, tuberculosis, psoriasis, and rheumatism. It is administered by intramuscular or subcutaneous injection.
Lignans are phenylpropanoid dimers found widely in plants. Podophyllum lignans from Podophyllum species have anticancer and antiviral properties. Their structure contains five rings. Phenylpropane units in lignans are derived from the phenylpropanoid pathway. Secoisolariciresinol diglucoside is a prominent lignan in flaxseed that has antioxidant and antiplatelet effects. Quassinoids from Quassia species have insecticidal, antibacterial, and antitumor properties. Their basic structure contains a beta-carbolinium ion.
The document describes different types of glycosides, which are compounds consisting of a sugar (glycon) bonded to another part (aglycon). Some examples of glycosides mentioned include:
- Anthraquinone glycosides like senna
- Sterol or cardiac glycosides like digitalis
- Saponine glycosides like liquorice
- The document also discusses different types of sugars that can form the glycon portion (glucose, rhamnose, pentose, fructose, arabinose) and different bonds between the glycon and aglycon (C-glycosides, N-glycosides).
- Some common uses of glycosides are as laxatives, anti
This document discusses lignans, which are non-flavonoid polyphenols found in many plant families. Lignans are dimers of phenylpropane units linked by carbon-carbon bonds and have antioxidant properties. They are classified into subgroups based on their carbon skeleton and cyclization patterns. Lignans are biosynthesized from phenylalanine and hydroxycinnamic acids via the shikimic acid pathway. Food sources of lignans include whole grains, seeds, nuts, fruits and vegetables. Lignans have therapeutic properties such as anticancer and antihypertensive effects. Some lignans are converted by gut bacteria into enterolignans, which may help lower cancer risks.
Alkaloidal amines ephedra, colchicum Pharmacognostic studyDivya Sree M S
This document provides information on the alkaloidal plants Ephedra and Colchicum. It describes their biological sources, geographical sources, cultivation methods, macroscopic and microscopic features, main chemical constituents including Ephedrine in Ephedra and Colchicine in Colchicum, chemical tests to identify the constituents, and traditional uses including as a bronchodilator and to treat gout respectively.
Pharmacognostic study of Saponin glycosides,
Pharmacognostic study of Liquorice, Pharmacognostic study of Ginseng, Pharmacognostic study of Sarasaprilla
Saponin glycosides are found in parts of plants and are used as detergents. Examples include the root of Saponaria officinalis. There are two types of aglycones: steroidal and triterpenoidal. Glycyrrhiza contains glycyrrhizic acid which produces glycyrrhizic acid and two molecules of glucuronic acid upon hydrolysis. It is used as a flavoring agent and for its demulcent, expectorant, and liver-protective properties. Sarsaparilla's active ingredient is sarsaponin which produces sarsapogenin and D-glucose and L-rhamnose upon hydrolysis. It is
This document discusses various terpenoid compounds found in plants, including iridoids, terpenes, and modified terpenoids. It provides classifications of terpenoids based on carbon atom count and discusses the occurrence, extraction, biosynthesis, and biological activities of specific compounds like iridoids, gentian, picrorhiza, quassia, tinospora, artemisia, taxus, and andrographis. Structures of important constituents from each plant are also shown.
This document provides an overview of pharmacognosy, including its definition, historical development, and modern applications. It discusses how pharmacognosy is the study of crude drugs from natural sources like plants, animals, and minerals. Over time, the field has advanced from early empirical use of natural remedies to the systematic isolation and characterization of active pharmaceutical ingredients using analytical techniques. Pharmacognosy continues to contribute to drug discovery and development through the study of natural products.
This document provides information on the extraction and identification of several phytoconstituents including curcumin, artemisinin, atropine, citral, menthol, caffeine, and reserpine. For each constituent, it describes the biological source, properties, extraction method from the source, and thin layer chromatography conditions and results for identification, including mobile phase, detecting agent, and Rf value.
Alkaloids are nitrogen-containing plant compounds that have physiological effects in humans and animals. They contain heterocyclic rings and can exist as primary, secondary, or tertiary amines. Common alkaloids include nicotine, atropine, and cocaine. In plants, alkaloids serve as defenses against herbivores and may aid growth. They are often crystalline solids that form salts and are soluble in non-polar solvents. Alkaloids have a wide range of pharmacological actions and can be classified based on their ring structures. Important alkaloid-containing plants discussed include belladonna, henbane, coca, and plants yielding quinine. Their biosynthesis often begins with amino acids
This document provides information about various plant-based fibers including cotton, jute, and hemp. It discusses the biological source, chemical composition, uses, and preparation processes for each fiber. Cotton fibers come from the seeds of cotton plants and are mainly used for absorbent cotton, surgical dressings, and filtering. The document outlines the ginning and scouring processes used to prepare cotton fibers. Jute fibers come from the stems of jute plants and are composed primarily of cellulose. They are used for wrapping bales. The retting process is described for extracting jute fibers from the stems. Identification tests are also listed to distinguish between different types of fibers.
Lignans and flavonoids are plant compounds with potential health benefits. Lignans are dimers of phenylpropanoids found in flaxseed and other foods. When consumed, lignan precursors are converted by gut bacteria into enterolactone and enterodiol, which have weak estrogenic activity and other biological effects. Flavonoids are polyphenols that include subclasses like flavones, flavonols, flavanones, and anthocyanins found in fruits and vegetables. They are associated with reduced disease risk due to their antioxidant and anti-inflammatory properties. Both lignans and flavonoids are derived from phenylalanine through the shikimate pathway and undergo enzymatic conversions in their
Pharmacognosy Families By AAA Arslan, Ayyaz, AsadMuhammad Latif
This document provides information on four plants from two families: Zingiberaceae and Liliaceae. It discusses turmeric from Zingiberaceae, including its chemical formula, uses as a spice and coloring agent, and curcumin as the active constituent. It then covers three plants from Liliaceae: squill including its use as a cardiac stimulant, aloe including its use as a laxative and barbaloin as the active constituent, and colchicum including its use to treat gout and colchicine as the active constituent.
systematics and production technology of cowpeaAvisha Budhani
This document provides an overview of cowpea (Vigna unguiculata), including its:
- Origin in Central Africa
- Classification within the plant kingdom and Fabaceae family
- Major subspecies cultivated, including V. unguiculata, V. cylindrica, and V. sesquipedalis
- Importance as a drought-resistant pulse crop grown in Africa and other warm regions
- Uses of mature seeds as a pulse and immature pods as a vegetable
The document summarizes information about the plant Catharanthus roseus, commonly known as Vinca or Periwinkle. It is native to Madagascar but cultivated in other tropical and subtropical regions. The plant contains important anticancer alkaloids vinblastine and vincristine in its leaves and roots. Vinblastine is used to treat Hodgkin's disease while vincristine is used for childhood leukemia. The flowers may also be used as a gentle laxative or gargle.
Pharmacognosy OF LIQUORICE(Saponin Glycoside)ALOK SINGH
This document summarizes information about the plant liquorice (Glycyrrhiza glabra). It is grown in sub-Himalayan regions and parts of Europe. Microscopically, it exhibits cork layers, medullary rays, phloem fibers, xylem vessels and fibers, and parenchyma cells containing starch grains and calcium oxalate crystals. It contains saponin glycosides and glycyrrhetinic acid. Liquorice has demulcent, expectorant, and mineralocorticoid properties and is used in cough syrups, lozenges, and to mask bitter tastes in medicines. Its saponins aid absorption of some drugs. Adulterants include
ISOLATION AND ESTIMATION OF GLYCERRHIZIN AND PHYLLANTHINnaseefa
This document discusses the isolation and estimation of two phytoconstituents - glycerrhizin from liquorice root and phyllanthin from Phyllanthus amarus. It describes the biological sources, chemical constituents, isolation methods including acid precipitation, alcohol extraction and ammonia extraction for glycerrhizin. For phyllanthin, the isolation involves extraction with petroleum ether followed by column chromatography. Estimation methods discussed are TLC densitometry, colorimetric and HPLC methods for glycerrhizin and TLC and HPLC for identifying and estimating phyllanthin.
Volatile oils can be extracted through three main methods: distillation, solvent extraction, and mechanical expression. Distillation involves boiling or steaming plant material to separate the oils, while solvent extraction soaks plants in solvents like alcohol. Mechanical expression ruptures oil cells without heat, as used for citrus peels.
Gentian is a plant whose dried rhizome and roots are used as a bitter tonic. It contains several bitter glycosides such as gentiopicrin, which has an intensely bitter taste and is used to stimulate digestion. Gentian grows in central and southern Europe and Asia, and its rhizomes are harvested in autumn after 2-5 years of growth. Microscopically, transverse sections of gentian rhizome show a porous wood surrounded by parenchyma cells containing oil globules and calcium oxalate needles. Gentian is used as a stomachic to treat indigestion and other gastrointestinal issues.
Glycosides are organic compounds found in plants and animals that contain a sugar moiety bonded to a non-sugar aglycon portion. They are classified based on the chemical nature of the aglycon, the nature of the sugar moiety, and the type of linkage between the glycon and aglycon. Glycosides are isolated using the Stas-Otto method involving successive extraction with alcohol and precipitation with lead acetate. Cardiac glycosides contain steroidal aglycons and are isolated from plants like Nerium oleander through alcoholic extraction, precipitation, and partitioning between organic solvents. Anthraquinone glycosides are isolated through successive extraction of the plant material with organic solvents and purification by column
Chaulmoogra oil is a fixed oil obtained from seeds of various Hydnocarpus species found in Myanmar. It contains chaulmoogric acid and hydnoctic acid as major constituents. Chaulmoogra oil has bactericidal effects against Mycobacterium leprae and M. tuberculosis, making it useful in the treatment of leprosy, tuberculosis, psoriasis, and rheumatism. It is administered by intramuscular or subcutaneous injection.
Lignans are phenylpropanoid dimers found widely in plants. Podophyllum lignans from Podophyllum species have anticancer and antiviral properties. Their structure contains five rings. Phenylpropane units in lignans are derived from the phenylpropanoid pathway. Secoisolariciresinol diglucoside is a prominent lignan in flaxseed that has antioxidant and antiplatelet effects. Quassinoids from Quassia species have insecticidal, antibacterial, and antitumor properties. Their basic structure contains a beta-carbolinium ion.
The document describes different types of glycosides, which are compounds consisting of a sugar (glycon) bonded to another part (aglycon). Some examples of glycosides mentioned include:
- Anthraquinone glycosides like senna
- Sterol or cardiac glycosides like digitalis
- Saponine glycosides like liquorice
- The document also discusses different types of sugars that can form the glycon portion (glucose, rhamnose, pentose, fructose, arabinose) and different bonds between the glycon and aglycon (C-glycosides, N-glycosides).
- Some common uses of glycosides are as laxatives, anti
This document discusses lignans, which are non-flavonoid polyphenols found in many plant families. Lignans are dimers of phenylpropane units linked by carbon-carbon bonds and have antioxidant properties. They are classified into subgroups based on their carbon skeleton and cyclization patterns. Lignans are biosynthesized from phenylalanine and hydroxycinnamic acids via the shikimic acid pathway. Food sources of lignans include whole grains, seeds, nuts, fruits and vegetables. Lignans have therapeutic properties such as anticancer and antihypertensive effects. Some lignans are converted by gut bacteria into enterolignans, which may help lower cancer risks.
Alkaloidal amines ephedra, colchicum Pharmacognostic studyDivya Sree M S
This document provides information on the alkaloidal plants Ephedra and Colchicum. It describes their biological sources, geographical sources, cultivation methods, macroscopic and microscopic features, main chemical constituents including Ephedrine in Ephedra and Colchicine in Colchicum, chemical tests to identify the constituents, and traditional uses including as a bronchodilator and to treat gout respectively.
Pharmacognostic study of Saponin glycosides,
Pharmacognostic study of Liquorice, Pharmacognostic study of Ginseng, Pharmacognostic study of Sarasaprilla
Saponin glycosides are found in parts of plants and are used as detergents. Examples include the root of Saponaria officinalis. There are two types of aglycones: steroidal and triterpenoidal. Glycyrrhiza contains glycyrrhizic acid which produces glycyrrhizic acid and two molecules of glucuronic acid upon hydrolysis. It is used as a flavoring agent and for its demulcent, expectorant, and liver-protective properties. Sarsaparilla's active ingredient is sarsaponin which produces sarsapogenin and D-glucose and L-rhamnose upon hydrolysis. It is
This document discusses various terpenoid compounds found in plants, including iridoids, terpenes, and modified terpenoids. It provides classifications of terpenoids based on carbon atom count and discusses the occurrence, extraction, biosynthesis, and biological activities of specific compounds like iridoids, gentian, picrorhiza, quassia, tinospora, artemisia, taxus, and andrographis. Structures of important constituents from each plant are also shown.
This document provides an overview of pharmacognosy, including its definition, historical development, and modern applications. It discusses how pharmacognosy is the study of crude drugs from natural sources like plants, animals, and minerals. Over time, the field has advanced from early empirical use of natural remedies to the systematic isolation and characterization of active pharmaceutical ingredients using analytical techniques. Pharmacognosy continues to contribute to drug discovery and development through the study of natural products.
This document provides information on the extraction and identification of several phytoconstituents including curcumin, artemisinin, atropine, citral, menthol, caffeine, and reserpine. For each constituent, it describes the biological source, properties, extraction method from the source, and thin layer chromatography conditions and results for identification, including mobile phase, detecting agent, and Rf value.
Alkaloids are nitrogen-containing plant compounds that have physiological effects in humans and animals. They contain heterocyclic rings and can exist as primary, secondary, or tertiary amines. Common alkaloids include nicotine, atropine, and cocaine. In plants, alkaloids serve as defenses against herbivores and may aid growth. They are often crystalline solids that form salts and are soluble in non-polar solvents. Alkaloids have a wide range of pharmacological actions and can be classified based on their ring structures. Important alkaloid-containing plants discussed include belladonna, henbane, coca, and plants yielding quinine. Their biosynthesis often begins with amino acids
This document provides information about various plant-based fibers including cotton, jute, and hemp. It discusses the biological source, chemical composition, uses, and preparation processes for each fiber. Cotton fibers come from the seeds of cotton plants and are mainly used for absorbent cotton, surgical dressings, and filtering. The document outlines the ginning and scouring processes used to prepare cotton fibers. Jute fibers come from the stems of jute plants and are composed primarily of cellulose. They are used for wrapping bales. The retting process is described for extracting jute fibers from the stems. Identification tests are also listed to distinguish between different types of fibers.
Lignans and flavonoids are plant compounds with potential health benefits. Lignans are dimers of phenylpropanoids found in flaxseed and other foods. When consumed, lignan precursors are converted by gut bacteria into enterolactone and enterodiol, which have weak estrogenic activity and other biological effects. Flavonoids are polyphenols that include subclasses like flavones, flavonols, flavanones, and anthocyanins found in fruits and vegetables. They are associated with reduced disease risk due to their antioxidant and anti-inflammatory properties. Both lignans and flavonoids are derived from phenylalanine through the shikimate pathway and undergo enzymatic conversions in their
Pharmacognosy Families By AAA Arslan, Ayyaz, AsadMuhammad Latif
This document provides information on four plants from two families: Zingiberaceae and Liliaceae. It discusses turmeric from Zingiberaceae, including its chemical formula, uses as a spice and coloring agent, and curcumin as the active constituent. It then covers three plants from Liliaceae: squill including its use as a cardiac stimulant, aloe including its use as a laxative and barbaloin as the active constituent, and colchicum including its use to treat gout and colchicine as the active constituent.
systematics and production technology of cowpeaAvisha Budhani
This document provides an overview of cowpea (Vigna unguiculata), including its:
- Origin in Central Africa
- Classification within the plant kingdom and Fabaceae family
- Major subspecies cultivated, including V. unguiculata, V. cylindrica, and V. sesquipedalis
- Importance as a drought-resistant pulse crop grown in Africa and other warm regions
- Uses of mature seeds as a pulse and immature pods as a vegetable
1) Pharmacognosy is the study of drugs from natural sources, especially medicinal plants. It draws from fields like botany, chemistry, and pharmacology.
2) Many important drugs were originally derived from plants, including morphine, quinine, taxol, and physostigmine. Extracting and isolating the active compounds from plants was an important early step in drug development.
3) While many plant-derived drugs can now be synthesized, plants remain an important source of new drug leads and templates for designing novel pharmaceuticals due to their vast chemical diversity and potential for novel structures. Extensive further screening of plants is still needed.
This document discusses alkaloids, which are nitrogen-containing organic compounds that have pharmacological effects on humans and animals. It defines three types of alkaloids - true alkaloids, protoalkaloids, and pseudoalkaloids - and provides examples of each type. The document also examines two specific alkaloid-containing plants - vinca and belladonna - describing their macroscopic characteristics, chemical constituents, and medicinal uses.
This document discusses alkaloids, which are nitrogen-containing organic compounds that have pharmacological effects on humans and animals. It defines three types of alkaloids - true alkaloids, protoalkaloids, and pseudoalkaloids - and provides examples of each type. The document also discusses two specific alkaloid-containing plants - vinca and belladonna - describing their chemical constituents and uses.
This document summarizes John Hutchinson's system of classification of flowering plants from the 1950s-1970s. Some key points:
- Hutchinson developed a phylogenetic system of classification based on evolutionary principles like trees being more primitive than herbs.
- His system was published in two volumes from 1926-1934 and revised until his death in 1972.
- He divided angiosperms into dicots and monocots, further dividing dicots into woody and herbaceous groups.
- Hutchinson proposed over 100 orders and families in his system based on characteristics like plant structure, reproduction methods, and flower morphology.
This document summarizes the major classes of plant hormones, including auxins, gibberellins, cytokinins, ethylene, and abscisic acid. It describes their roles in processes like cell elongation, fruit ripening, dormancy, and responses to stress. The document also discusses some newer identified plant hormones and their functions, as well as potential medical applications of harnessing plant hormones to target cancer cells.
Flavonoids are a group of plant secondary metabolites called phenolics. They contain an aromatic ring structure with one or more hydroxyl groups attached. There are over 3000 known flavonoids found throughout plants. Flavonoids may function as antioxidants, pigments, and have potential health benefits for humans. Common tests used to identify flavonoids include the Shinoda test and ferric chloride test.
This document provides an overview of plant taxonomy including its objectives, main references, and course syllabus. It discusses key concepts in plant taxonomy such as identification, classification, and nomenclature. It also summarizes several important plant families including Asteraceae, Fabaceae, Poaceae, Brassicaceae, Apiaceae, Lamiaceae, and Rosaceae. Methods of plant taxonomy are outlined including morphology, floristics, herbaria, and botanical gardens. The importance of field observation and a region's flora are also noted.
This document provides information on four plants from the Lily family (Liliaceae): Colchicum, Aloe, Garlic. It describes their botanical origins, parts used, constituents, and medical uses. Colchicum contains alkaloids like colchicine used to treat gout and cancer. Aloe gel is used topically for burns and skin issues. Garlic contains volatile oils and is used for various conditions like asthma, cholesterol, infection. The document defines characteristics of Liliaceae plants and provides details on morphology and taxonomy.
Lignans.pptx Use of microbes in industry. Production of Enzymes- General cons...Rakesh Barik
Lignans are a class of plant polyphenols composed of two linked phenylpropane units. They are found in various plant families and act as antioxidants and defenses against pathogens. The basic lignan structure consists of two phenylpropane units linked by a C-C bond between their central carbons. Major subclasses include furofuran, furan, and dibenzylbutane lignans. Lignans have various biological activities including anticancer, anti-inflammatory, and antioxidant effects. They are often present in plants as glycosylated derivatives and some common examples include secoisolariciresinol and podophyllotoxin.
Family Leguminosae (Fabaceae) is generally characterized by typical legume fruit and the ability to symbiotically fix nitrogen. Among the three subfamilies, Papilionoideae is the largest and possesses the lion’s share of economically important legumes including pulses and forages. Although monophyletic origin is generally considered, traces of polyphyly and paraphyly are evidenced in the subfamilies Mimosoideae and Caesalpinioideae by molecular phylogenetic studies. Development of robust cytogenetic stocks (aneuploids, polyploids, chromosomal aberrations, somaclonal variants, transformants, etc.) and novel functional genomic tools (mutants, molecular markers, DNA libraries, barcode sequences, etc.) have paved the way to legume classical and molecular breeding for high-yield, nutritional quality, biotic and abiotic stress tolerance, and enhancement of its bioactive natural antioxidants.
These documents discuss different types of plant compounds including isoflavones, flavones, and depsides. Isoflavones are plant compounds related to isoflavonoids that can act as phytoestrogens in mammals. They are produced almost exclusively by legumes. Flavones are a class of flavonoids that contain yellow pigments found in plants. Depsides are polyphenolic compounds composed of aromatic units linked by ester bonds that are commonly found in lichens and have various biological activities like antibiotic and anti-inflammatory properties.
Vinca, also known as Catharanthus roseus, is a plant native to Madagascar that is cultivated in tropical and subtropical regions for its anticancer alkaloids vinblastine and vincristine. The plant is perennial and cultivated by direct sowing or in nurseries. It has glossy green leaves and red, pink, or white flowers. Microscopy shows dorsiventral leaf structure with palisade parenchyma below the upper epidermis. The plant contains over 90 alkaloids, notably the dimer alkaloids vinblastine and vincristine which are used to treat cancers like Hodgkin's lymphoma and leukemia. Extracts and alkaloids from v
Hyoscyamus, also known as henbane, is a poisonous plant species native to Europe, Western Asia, and Northern Africa. It has been used medicinally since ancient times to relieve spasms and as a sedative. The plant contains important alkaloids like hyoscyamine and scopolamine. It is cultivated for its leaves and flowering tops, which are used as a drug containing not less than 0.05% alkaloids. The leaves are pale greyish-green with an acrid, bitter taste and triangular lobes. Hyoscyamus is used as an antispasmodic, expectorant, and to reduce salivary and bronchial secretions. Overdose can
Cannabis sativa is an annual herbaceous flowering plant indigenous to Eastern Asia but now of cosmopolitan distribution due to widespread cultivation.[1] It has been cultivated throughout recorded history, used as a source of industrial fiber, seed oil, food, recreation, religious and spiritual moods and medicine. Each part of the plant is harvested differently, depending on the purpose of its use. The species was first classified by Carl Linnaeus in 1753.[2] The word "sativa" means things that are cultivated.
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Swathi Gariganti is an assistant professor at Sree Dattha Institute of Pharmacy who teaches subjects related to pharmacognosy and phytochemistry. This document provides details about the plant Catharanthus roseus including its synonyms, biological source, geographical source, history of use, cultivation and collection methods, macroscopic and microscopic characters, chemical constituents, uses, and dose. It also summarizes information on the cultivation, collection, and chemical constituents of Rauwolfia serpentina.
This document provides summaries of several plant families, including their botanical descriptions, characteristics, commonly used species, and growing requirements. It discusses families such as Mallow/Malvaceae, Poppy/Papaveraceae, Fumitory/Fumariaceae, Plantain/Plantaginaceae, and others. The document emphasizes the importance of crop rotation by not planting related plant families in the same spot more than every three years to maintain soil health.
Natural sweetener which have low calorific value, can be used in diabetic and obese patient. some of them are taste modifying agents, which are not sweet in taste but modify the taste of sour food, can be used as natural sweetener instead of artificial sweetening agents which are high in calorie and can be harmful to our body.
Herbal excipients which are easily available, lower cost and are noncarcinogenic, which can be used to replace synthetic excipients which are carcinogenic.
Natural colorants obtained from various insects and plants, which gives harmless dying agents which can be used in food industry as well as textile industry.
Isolation, Identification and Analysis of Phytoconstituents.pptxZuli Shingala
general Isolation methods for alkaloids
isolation, identification and analysis of phytoconstituents like Caffeine, Atropine, Glycyrrhetinic acid, Podophyllotoxin
Cyanogenic glycoside which on hydrolysis gives benzaldehyde and hydrocyanic acid. examples of this glycosides are bitter almond and wild cherry bark. in this slides bitter almond is described in detail.
Black and green tea, its preparation, tea cultivation, preparation of black tea and green tea, chemical constituents (caffeine, catechin, tannins) and uses
Opium is a dried exudate obtained from incisions made on unripe pods of the opium poppy (Papaver somniferum). It contains several alkaloids, including morphine and codeine. Opium poppies are cultivated in parts of India, Pakistan, Afghanistan, and other countries under government control due to its narcotic properties. The poppies are incised to extract a milky latex which dries into raw opium and is collected, processed, and used to isolate alkaloids like morphine for medicinal purposes as a potent analgesic, though it is highly addictive.
Plant hormones, also known as phytohormones, control plant growth and development processes including germination, growth, flowering, fruit ripening and senescence. The major plant hormones are auxins, gibberellins, cytokinins, abscisic acid, and ethylene. Auxins promote stem elongation and growth, stimulate fruit growth, and induce root formation. Gibberellins stimulate stem elongation, control flowering, and break seed dormancy. Cytokinins promote cell division and stimulate shoot and root growth. Abscisic acid inhibits seed germination and induces dormancy while ethylene induces fruit ripening and flowering.
Cultivation and collection of drugs of natural originZuli Shingala
cultivation and collection of medicinal plants, processing, storage, etc. with various factors that affects cultivation and collection of medicinal plants
Secondary metabolites from plants like Alkaloids, Glycosides, Tannins, Resins, Volatile oils and Flavonoids. with definition, introduction, Chemical properties, Classification and Identification test
Gluconeogenesis is the synthesis of glucose from non-carbohydrate precursors mainly in the liver and kidneys. It is important for supplying glucose to tissues between meals and during fasting. The key substrates are lactate, pyruvate, amino acids, glycerol, and propionate. Gluconeogenesis bypasses the irreversible steps of glycolysis using alternate enzymes and requires energy in the form of ATP and GTP. It is regulated by hormones like glucagon and availability of substrates.
The citric acid cycle (Krebs cycle or TCA cycle) is an important metabolic pathway that generates energy through the oxidation of acetyl-CoA derived from carbohydrates, fats, and proteins. It occurs in the matrix of mitochondria and involves 8 steps where acetyl-CoA derived from pyruvate combines with oxaloacetate to form citrate. As the citrate undergoes oxidation, NADH, FADH2, and GTP are produced, leading to the generation of 12 ATP per acetyl-CoA molecule. The cycle regenerates oxaloacetate and continues.
This document discusses drug adulteration in herbal medicines. It defines adulteration as substituting the original medicinal plant partially or wholly with other similar-looking substances that are inferior in quality. Adulteration can occur intentionally for commercial gain or unintentionally due to misidentification, lack of knowledge about the authentic plant, morphological similarities between plants, lack of the authentic plant, or careless collection practices. The document outlines various types of intentional and unintentional adulteration and provides examples.
evaluation of drug by organoleptic, microscopical, physical, chemical and biological methods. spectroscopical methods, chromatography, leaf constants, linear measurements.
metabolism of glucose into pyruvate or lactate depending upon the presence of oxygen. salient features of glycolysis, definition and sequence of reactions involved in glycolysis.
classification of drugs from natural origin
alphabetical, morphological, pharmacological, chemical, taxonomical, chemotaxonomical, serotaxonomical classifications are included in the presentation
Nutraceuticals – let food be your medicineZuli Shingala
This document provides information on various nutraceuticals that can provide health benefits. It discusses broccoli, green tea, herbal tea, flax seeds, black cohosh, and turmeric. For each item, it describes the plant/ingredient, chemical constituents, preparation methods, and health benefits. Key health benefits highlighted across the nutraceuticals include antioxidant effects, cancer prevention, lowering cholesterol, aiding digestion, anti-inflammatory properties, and relief from menopausal symptoms.
herbal drugs or phytoconstituents used to improve skin texture and coloration included in the presentation with herbal fairness formulations available in the market
Sources of crude drugs (natural)
Drugs obtained from Plants, Animals, Marine, Microorganism, Mineral and from Biotechnology (plant tissue culture) are covered in the presentation
The skin is the largest organ and its health plays a vital role among the other sense organs. The skin concerns like acne breakout, psoriasis, or anything similar along the lines, finding a qualified and experienced dermatologist becomes paramount.
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share - Lions, tigers, AI and health misinformation, oh my!.pptxTina Purnat
• Pitfalls and pivots needed to use AI effectively in public health
• Evidence-based strategies to address health misinformation effectively
• Building trust with communities online and offline
• Equipping health professionals to address questions, concerns and health misinformation
• Assessing risk and mitigating harm from adverse health narratives in communities, health workforce and health system
Osteoporosis - Definition , Evaluation and Management .pdfJim Jacob Roy
Osteoporosis is an increasing cause of morbidity among the elderly.
In this document , a brief outline of osteoporosis is given , including the risk factors of osteoporosis fractures , the indications for testing bone mineral density and the management of osteoporosis
Mercurius is named after the roman god mercurius, the god of trade and science. The planet mercurius is named after the same god. Mercurius is sometimes called hydrargyrum, means ‘watery silver’. Its shine and colour are very similar to silver, but mercury is a fluid at room temperatures. The name quick silver is a translation of hydrargyrum, where the word quick describes its tendency to scatter away in all directions.
The droplets have a tendency to conglomerate to one big mass, but on being shaken they fall apart into countless little droplets again. It is used to ignite explosives, like mercury fulminate, the explosive character is one of its general themes.
Does Over-Masturbation Contribute to Chronic Prostatitis.pptxwalterHu5
In some case, your chronic prostatitis may be related to over-masturbation. Generally, natural medicine Diuretic and Anti-inflammatory Pill can help mee get a cure.
Kosmoderma Academy, a leading institution in the field of dermatology and aesthetics, offers comprehensive courses in cosmetology and trichology. Our specialized courses on PRP (Hair), DR+Growth Factor, GFC, and Qr678 are designed to equip practitioners with advanced skills and knowledge to excel in hair restoration and growth treatments.
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptxHolistified Wellness
We’re talking about Vedic Meditation, a form of meditation that has been around for at least 5,000 years. Back then, the people who lived in the Indus Valley, now known as India and Pakistan, practised meditation as a fundamental part of daily life. This knowledge that has given us yoga and Ayurveda, was known as Veda, hence the name Vedic. And though there are some written records, the practice has been passed down verbally from generation to generation.
2. • In 1936, Haworth defined lignans as “Phenylpropanoid dimers consisting of
two phenyl propane units (C6C3) linked by their central C8 carbon.”
• Lignans are a subgroup of non-flavonoid polyphenols.
• Occurrence of Lignans
• They are widely distributed in plant kingdom, being present in more than 55
plant families, where they act as antioxidants and defence molecules against
pathogenic fungi and bacteria. Usually occur in root, stem, bark, fruits and seed
parts of plant.
3. • SUNFLOWER SEEDS:
• B.S.: It consists of the dried fully ripe seeds of Helianthus
annuus L. belonging to family Asteraceae
• Larisiresinol
Sources of lignans
4. • PUMPKIN SEEDS:
• B.S.: It consists of the dried fully ripe seeds of Cucurbita maxima
belonging to family Cucurbitaceae.
• Secoisolariciresinol
5. • FLAX SEEDS:
• B.S.: It consists of the dried fully ripe seeds of Linum usitatissimum Linn.
belonging to family Liliaceae.
Secoisolariciresinol Diglucoside (SDG)
• 1 ounce of flaxseed contains 85mg of lignans
Secoisolariciresinol Diglucoside
6. • SESAME SEEDS:
• B.S.: It consists of the dried fully ripe seeds of Sesamum
indicum Linn. belonging to family Pedaliaceae.
• Sesamin
1 ounce of sesame seeds contain 11 mg of lignans
7. • OTHER SOURCES:
• Wheat: 7-hydroxymatairesinol
• Corn: 7-hydroxymatairesinol
• Strawberry: Pinoresinol
• Pea: Pinoresinol
• Broccoli: Larisiresinol
• ROLE OF LIGNAN IN PLANT
• Participate in defensive mechanism against pathogens due
to its antiviral, anti-bacterial and anti-fungal properties.