Easy & to the point Topics are clearly given in this presentation..
Thanks & Best Regard
(Anurag Pandey) B.Pharm
Contact :- anurag.dmk05@gmail.com (Facebook & Gmail both)
Easy & to the point Topics are clearly given in this presentation..
Thanks & Best Regard
(Anurag Pandey) B.Pharm
Contact :- anurag.dmk05@gmail.com (Facebook & Gmail both)
SUSTAINED RELEASE (SR) & CONTROL RELEASE.pptxRAHUL PAL
Sustained-release medications are usually labeled with “SR” at the end of their name. These medications prolong the medication's release from a tablet or capsule so that you'll get the medication's benefits over a longer period of time.
CR = controlled release, SR = sustained release, ER = extended release, IR = immediate release. *
formulation development of Transdermal drug delivery systems i.e. transdermal patches, compostion of transdermal patch, physical methods used to prepare tansdermal patch
SUSTAINED RELEASE (SR) & CONTROL RELEASE.pptxRAHUL PAL
Sustained-release medications are usually labeled with “SR” at the end of their name. These medications prolong the medication's release from a tablet or capsule so that you'll get the medication's benefits over a longer period of time.
CR = controlled release, SR = sustained release, ER = extended release, IR = immediate release. *
formulation development of Transdermal drug delivery systems i.e. transdermal patches, compostion of transdermal patch, physical methods used to prepare tansdermal patch
microencapsulation is the part of an pharmaceutics, in that the method of preperation is giving. and all related thing about microencapsulation is given.
thanks you.
This presentation includes information related to the different technologies used for preparation of micro-capsules and also their evaluation parameters.
Synthetic Fiber Construction in lab .pptxPavel ( NSTU)
Synthetic fiber production is a fascinating and complex field that blends chemistry, engineering, and environmental science. By understanding these aspects, students can gain a comprehensive view of synthetic fiber production, its impact on society and the environment, and the potential for future innovations. Synthetic fibers play a crucial role in modern society, impacting various aspects of daily life, industry, and the environment. ynthetic fibers are integral to modern life, offering a range of benefits from cost-effectiveness and versatility to innovative applications and performance characteristics. While they pose environmental challenges, ongoing research and development aim to create more sustainable and eco-friendly alternatives. Understanding the importance of synthetic fibers helps in appreciating their role in the economy, industry, and daily life, while also emphasizing the need for sustainable practices and innovation.
2024.06.01 Introducing a competency framework for languag learning materials ...Sandy Millin
http://sandymillin.wordpress.com/iateflwebinar2024
Published classroom materials form the basis of syllabuses, drive teacher professional development, and have a potentially huge influence on learners, teachers and education systems. All teachers also create their own materials, whether a few sentences on a blackboard, a highly-structured fully-realised online course, or anything in between. Despite this, the knowledge and skills needed to create effective language learning materials are rarely part of teacher training, and are mostly learnt by trial and error.
Knowledge and skills frameworks, generally called competency frameworks, for ELT teachers, trainers and managers have existed for a few years now. However, until I created one for my MA dissertation, there wasn’t one drawing together what we need to know and do to be able to effectively produce language learning materials.
This webinar will introduce you to my framework, highlighting the key competencies I identified from my research. It will also show how anybody involved in language teaching (any language, not just English!), teacher training, managing schools or developing language learning materials can benefit from using the framework.
The French Revolution, which began in 1789, was a period of radical social and political upheaval in France. It marked the decline of absolute monarchies, the rise of secular and democratic republics, and the eventual rise of Napoleon Bonaparte. This revolutionary period is crucial in understanding the transition from feudalism to modernity in Europe.
For more information, visit-www.vavaclasses.com
June 3, 2024 Anti-Semitism Letter Sent to MIT President Kornbluth and MIT Cor...Levi Shapiro
Letter from the Congress of the United States regarding Anti-Semitism sent June 3rd to MIT President Sally Kornbluth, MIT Corp Chair, Mark Gorenberg
Dear Dr. Kornbluth and Mr. Gorenberg,
The US House of Representatives is deeply concerned by ongoing and pervasive acts of antisemitic
harassment and intimidation at the Massachusetts Institute of Technology (MIT). Failing to act decisively to ensure a safe learning environment for all students would be a grave dereliction of your responsibilities as President of MIT and Chair of the MIT Corporation.
This Congress will not stand idly by and allow an environment hostile to Jewish students to persist. The House believes that your institution is in violation of Title VI of the Civil Rights Act, and the inability or
unwillingness to rectify this violation through action requires accountability.
Postsecondary education is a unique opportunity for students to learn and have their ideas and beliefs challenged. However, universities receiving hundreds of millions of federal funds annually have denied
students that opportunity and have been hijacked to become venues for the promotion of terrorism, antisemitic harassment and intimidation, unlawful encampments, and in some cases, assaults and riots.
The House of Representatives will not countenance the use of federal funds to indoctrinate students into hateful, antisemitic, anti-American supporters of terrorism. Investigations into campus antisemitism by the Committee on Education and the Workforce and the Committee on Ways and Means have been expanded into a Congress-wide probe across all relevant jurisdictions to address this national crisis. The undersigned Committees will conduct oversight into the use of federal funds at MIT and its learning environment under authorities granted to each Committee.
• The Committee on Education and the Workforce has been investigating your institution since December 7, 2023. The Committee has broad jurisdiction over postsecondary education, including its compliance with Title VI of the Civil Rights Act, campus safety concerns over disruptions to the learning environment, and the awarding of federal student aid under the Higher Education Act.
• The Committee on Oversight and Accountability is investigating the sources of funding and other support flowing to groups espousing pro-Hamas propaganda and engaged in antisemitic harassment and intimidation of students. The Committee on Oversight and Accountability is the principal oversight committee of the US House of Representatives and has broad authority to investigate “any matter” at “any time” under House Rule X.
• The Committee on Ways and Means has been investigating several universities since November 15, 2023, when the Committee held a hearing entitled From Ivory Towers to Dark Corners: Investigating the Nexus Between Antisemitism, Tax-Exempt Universities, and Terror Financing. The Committee followed the hearing with letters to those institutions on January 10, 202
Unit 8 - Information and Communication Technology (Paper I).pdfThiyagu K
This slides describes the basic concepts of ICT, basics of Email, Emerging Technology and Digital Initiatives in Education. This presentations aligns with the UGC Paper I syllabus.
Macroeconomics- Movie Location
This will be used as part of your Personal Professional Portfolio once graded.
Objective:
Prepare a presentation or a paper using research, basic comparative analysis, data organization and application of economic information. You will make an informed assessment of an economic climate outside of the United States to accomplish an entertainment industry objective.
Read| The latest issue of The Challenger is here! We are thrilled to announce that our school paper has qualified for the NATIONAL SCHOOLS PRESS CONFERENCE (NSPC) 2024. Thank you for your unwavering support and trust. Dive into the stories that made us stand out!
How to Make a Field invisible in Odoo 17Celine George
It is possible to hide or invisible some fields in odoo. Commonly using “invisible” attribute in the field definition to invisible the fields. This slide will show how to make a field invisible in odoo 17.
Operation “Blue Star” is the only event in the history of Independent India where the state went into war with its own people. Even after about 40 years it is not clear if it was culmination of states anger over people of the region, a political game of power or start of dictatorial chapter in the democratic setup.
The people of Punjab felt alienated from main stream due to denial of their just demands during a long democratic struggle since independence. As it happen all over the word, it led to militant struggle with great loss of lives of military, police and civilian personnel. Killing of Indira Gandhi and massacre of innocent Sikhs in Delhi and other India cities was also associated with this movement.
Embracing GenAI - A Strategic ImperativePeter Windle
Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
This Gasta posits a strategic approach to integrating AI into HEIs to prepare staff, students and the curriculum for an evolving world and workplace. We will highlight the advantages of working with these technologies beyond the realm of teaching, learning and assessment by considering prompt engineering skills, industry impact, curriculum changes, and the need for staff upskilling. In contrast, not engaging strategically with Generative AI poses risks, including falling behind peers, missed opportunities and failing to ensure our graduates remain employable. The rapid evolution of AI technologies necessitates a proactive and strategic approach if we are to remain relevant.
Introduction to AI for Nonprofits with Tapp NetworkTechSoup
Dive into the world of AI! Experts Jon Hill and Tareq Monaur will guide you through AI's role in enhancing nonprofit websites and basic marketing strategies, making it easy to understand and apply.
2. Definition
Need of Microencapsulation
Advantages
Fundamental consideration
Techniques
Applications
References
3. DEFINITION: A process by which solid , droplets of liquid and
dispersion can be enclosed in microscopic particle by the formation
of thin coating of wall material around the substance.
INTRODUCTION
Core material Wall material
Coating
5. To Increase of bioavailability.
To alter the drug release.
To produce a targeted drug delivery.
To protect the core from outside environment.
To decrease evaporation rate of the volatile core material.
To convert liquid into solid form.
To mask the core taste.
Protects the GIT from irritant effects of the drug.
6. FUNDAMENTAL CONSIDERATION:
Core material Coating material Vehicle
Solid Liquid
Microencapsulation
Polymers
Waxes
Aqueous No aqueous
Resins
Proteins
Polysaccharides
7. The material to be coated.
It may be liquid or solid in nature.
Liquid core may be dissolved or dispersed material.
COMPOSITION OF CORE MATERIAL:
Drug or active constituent
Additive like diluents
CORE MATERIAL:
8. IDEAL CHARACTERISTICS:
Capable of forming a film cohesive with core material.
It should be compatible with the core material.
It Should be stable, non reactive.
Provide desired coating properties like strength, flexibility&
impermeability.
COMPOSITION OF COATING:
Inert polymer
Plasticizer
Coloring agent
COATING MATERIAL:
9. 1. MICROENCAPSULATION TECHNIQUES:
1. Air suspension technique (Wurster)
2. Coacervation-Phase separation process
3. Spray drying & spray congealing
4. Multiorifice Centrifugation Process
5. Pan coating
6. Solvent evaporation
7. Polymerization
8. Nozzle vibration technology
9. Jet cutter technology
10. Extrusion
11. Single & double emulsion techniques
12. Supercritical fluid anti solvent method (SAS)
14. Used for large size particles i.e. 600-5000 μm size.
Coating pan is used for this operation.
Coating solution is applied as a solution or atomized
spray on sugar pellets (Non-pareil sugar seeds).
Warm air is passed to remove the coating solvent.
15.
16. Polymer
+ Volatile organic solvent
Organic Polymeric Phase
Formation of Oil-in-Water
Emulsion
Solvent Evaporation
Particle Formation by Polymer
Precipitation
RECOVERY OF POLYMERIC
MICROPARTICLES
Temperature increase
Active Ingredient
Addition into an aqueous
phase (+o/w stabilizer)
5.SOLVENT
EVAPORATION:
17. 6.SPRAY DRYING & CONGEALING :
Spray drying : spray = aqueous solution / Hot air
Spray congealing : spray = hot melt/cold air
18. 7.POLYMERIZATION:
Method developed by Chang
Interfacial polymerization..
Aliphatic diamine Dicarboxilic acid halide
Liq- Liq. interface
polymerization Microspheres
19. (D) Vibration technology
•This technology is based on an ancient principle (Lord
Rayleigh, in the late 19th century) which shown that a
laminar liquid jet breaks up into equally sized droplets by
a superimposed vibration. The parameters are the
frequency, the velocity of the jet and the nozzle diameter.
•To guarantee the production of uniform beads or
capsules and to avoid large size distributions due to
coalescence effects during the flight, the droplets pass
through an electrostatic field to be charged. As a result
these droplets don’t hit each other during the flight and
will be spread over a larger surface of the gelation bath
thus resulting in monodisperse beads.
20.
21. (E) JetCutter technology
The JetCutter is a simple technology for bead production that meets
the requirement of producing monodisperse beads originating from
low up to high viscous fluids with a high throughput `
24. ADVANTAGE OF MICROENCAPSULATION
• administered dose of a
drug is subdivided into
small units that are
spread over a large area
of the gastrointestinal
tracts, which may
enhance absorption by
diminishing local drug
concentration
• Micro-K ExtenCaps
25. Its costly process, not economical.
More skill is required.
It is difficult to get continuous & uniform film.
26. 1.Microcapsules: The active agent forms a core surrounded by an
inert diffusion barrier.
2.Microspheres: The active agent is dispersed or dissolved in an
inert polymer.
27.
28. Stability testing
Size of microcapsules- Sieving Method
Amount of drug present In microcapsules
Dissolution test- Invitro drug release
29. Leon, L., Herbert A. L., Joseph, L. K; “ The Theory And
Practice Of Industrial Pharmacy”, 3rd edition (1990),
Varghese Publishing House, Page no. 412-428.
Vyas S.P, Khar R.K; “Targeted & Controlled drug
delivery ’’ Novel carrier systems,1st
edition (2002),CBS
publisher & distributors New delhi, page no.418-455.
Wise D.L, “Handbook of pharmaceutical controlled
release technology”1st
edition , Marcel Dekker New York,
page no. 271-286,