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controlled drug delivery system classification

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The document discusses different types of controlled drug delivery systems classified by physical or chemical means of activation. The key types are: 1. Osmotically activated systems where drug release is controlled by osmotic pressure gradients. 2. Mechanically activated systems like metered-dose inhalers that use manual activation to deliver precise drug doses. 3. Iontophoresis-activated systems where an electrical current enhances absorption of ionic drugs through the skin. 4. pH-activated systems that target drug delivery to specific pH ranges, like coatings protecting gastric drugs from stomach acid.

Health & Medicine
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Controlled Drug Delivery System Classification
Activation-modulated Drug Delivery System ,[object Object],[object Object],22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
Classification : By Physical Means 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P. Activation- Modulated DDS Osmotic pressure Activated
Osmotic Pressure Activated DDS 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P. Drug reservoir ( API + osmotic agent) Delivery Orifice Semi-permeable Membrane. (cellulose esters)
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P. ( π s – π e ) = ( π s – π e ) Sd =
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P. Alzet Osmotic Pump
Classification : By Physical Means 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P. Activation- Modulated DDS Osmotic pressure Activated Hydrodynamic Press. Activated
Hydrodynamic Pressure - Activated DDS 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P. Q Pf Am t hm = (  s -  e )
[object Object],[object Object],[object Object],[object Object],22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
Classification : By Physical Means 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P. Activation- Modulated DDS Osmotic pressure Activated Hydrodynamic Press. Activated Vapor Pressure Activated
Vapor Pressure – Activated DDS 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
Classification : By Physical Means 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P. Activation- Modulated DDS Osmotic pressure Activated Hydrodynamic Press. Activated Vapor Pressure Activated Mechanically Activated
Mechanically – Activated DDS ,[object Object],[object Object],22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
[object Object],[object Object],22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
Classification : By Physical Means 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P. Activation- Modulated DDS Osmotic pressure Activated Hydrodynamic Press. Activated Vapor Pressure Activated Mechanically Activated Magnetically Activated
Magnetically Activated - DDS 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
[object Object],[object Object],[object Object],22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
[object Object],[object Object],22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
Classification : By Physical Means 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P. Activation- Modulated DDS Osmotic pressure Activated Hydrodynamic Press. Activated Vapor Pressure Activated Mechanically Activated Magnetically Activated Sonophoresis Activated
Sonophoresis - Activated DDS ,[object Object],[object Object],22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
Classification : By Physical Means 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P. Activation- Modulated DDS Osmotic pressure Activated Hydrodynamic Press. Activated Vapor Pressure Activated Mechanically Activated Magnetically Activated Sonophoresis Activated Ionto- phoresis Activated
Iontophoresis - Activated DDS ,[object Object],[object Object],22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
[object Object],[object Object],[object Object],[object Object],[object Object],22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
Merits : ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
Classification : By Physical Means 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P. Activation- Modulated DDS Osmotic pressure Activated Hydrodynamic Press. Activated Vapor Pressure Activated Mechanically Activated Magnetically Activated Sonophoresis Activated Ionto- phoresis Activated Hydration Activated
Hydration - Activated DDS 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P. Valrelease Tablets
[object Object],[object Object],22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
Classification By : Chemical Means 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P. Activation- Modulated DDS pH-Activated DDS
pH-Activated DDS ,[object Object],[object Object],[object Object],22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
Classification By : Chemical Means 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P. Activation- Modulated DDS pH-Activated DDS Ion-Activated DDS
Ion-Activated DDS 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
[object Object],[object Object],[object Object],22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
[object Object],[object Object],[object Object],22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
Classification By : Chemical Means 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P. Activation- Modulated DDS pH-Activated DDS Ion-Activated DDS Hydrolysis-Activated DDS
Hydrolysis-Activated DDS ,[object Object],[object Object],22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
[object Object],[object Object],[object Object],[object Object],22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
Classification By : Biochemical Means ,[object Object],[object Object],[object Object],22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
[object Object],[object Object],22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
Feedback Regulated Drug Delivery System ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
A. Bioerosion - Regulated DDS 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
.Bioresponsive DDS ,[object Object],[object Object],22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
C. Self-Regulating DDS ,[object Object],[object Object],[object Object],22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
Effect Of System Parameters On CDDS 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P. ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Polymer Solubility ,[object Object],[object Object],[object Object],22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
Solution Solubility ,[object Object],[object Object],[object Object],22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
Partition Coefficient ,[object Object],[object Object],[object Object],[object Object],[object Object],22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
[object Object],[object Object],22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
Polymer Diffusivity ,[object Object],22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
Solution Diffusivity ,[object Object],[object Object],[object Object],22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P. ,[object Object],[object Object],[object Object]
Reference ,[object Object],[object Object],[object Object],[object Object],[object Object],22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P. ?

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controlled drug delivery system classification

  • 1. Controlled Drug Delivery System Classification
  • 2.
  • 3. Classification : By Physical Means 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P. Activation- Modulated DDS Osmotic pressure Activated
  • 4. Osmotic Pressure Activated DDS 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P. Drug reservoir ( API + osmotic agent) Delivery Orifice Semi-permeable Membrane. (cellulose esters)
  • 5.
  • 6.
  • 7.
  • 8. 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P. Alzet Osmotic Pump
  • 9. Classification : By Physical Means 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P. Activation- Modulated DDS Osmotic pressure Activated Hydrodynamic Press. Activated
  • 10. Hydrodynamic Pressure - Activated DDS 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
  • 11.
  • 12.
  • 13. Classification : By Physical Means 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P. Activation- Modulated DDS Osmotic pressure Activated Hydrodynamic Press. Activated Vapor Pressure Activated
  • 14. Vapor Pressure – Activated DDS 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
  • 15.
  • 16.
  • 17. Classification : By Physical Means 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P. Activation- Modulated DDS Osmotic pressure Activated Hydrodynamic Press. Activated Vapor Pressure Activated Mechanically Activated
  • 18.
  • 19.
  • 20. Classification : By Physical Means 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P. Activation- Modulated DDS Osmotic pressure Activated Hydrodynamic Press. Activated Vapor Pressure Activated Mechanically Activated Magnetically Activated
  • 21. Magnetically Activated - DDS 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
  • 22.
  • 23.
  • 24. Classification : By Physical Means 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P. Activation- Modulated DDS Osmotic pressure Activated Hydrodynamic Press. Activated Vapor Pressure Activated Mechanically Activated Magnetically Activated Sonophoresis Activated
  • 25.
  • 26. 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
  • 27. Classification : By Physical Means 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P. Activation- Modulated DDS Osmotic pressure Activated Hydrodynamic Press. Activated Vapor Pressure Activated Mechanically Activated Magnetically Activated Sonophoresis Activated Ionto- phoresis Activated
  • 28.
  • 29.
  • 30. 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
  • 31.
  • 32. Classification : By Physical Means 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P. Activation- Modulated DDS Osmotic pressure Activated Hydrodynamic Press. Activated Vapor Pressure Activated Mechanically Activated Magnetically Activated Sonophoresis Activated Ionto- phoresis Activated Hydration Activated
  • 33. Hydration - Activated DDS 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P. Valrelease Tablets
  • 34.
  • 35. Classification By : Chemical Means 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P. Activation- Modulated DDS pH-Activated DDS
  • 36.
  • 37. 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
  • 38. Classification By : Chemical Means 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P. Activation- Modulated DDS pH-Activated DDS Ion-Activated DDS
  • 39. Ion-Activated DDS 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
  • 40.
  • 41.
  • 42. Classification By : Chemical Means 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P. Activation- Modulated DDS pH-Activated DDS Ion-Activated DDS Hydrolysis-Activated DDS
  • 43.
  • 44.
  • 45.
  • 46.
  • 47.
  • 48. A. Bioerosion - Regulated DDS 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
  • 49.
  • 50. 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
  • 51.
  • 52. 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P.
  • 53.
  • 54.
  • 55.
  • 56.
  • 57.
  • 58.
  • 59.
  • 60.
  • 61.
  • 62.
  • 63. 22/01/2011 B R Nahata College of Pharmacy ,Mandsaur M.P. ?