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Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Dee Unglaub Silverthorn, Ph.D.
HUMAN PHYSIOLOGY
PowerPoint®
Lecture Slide Presentation by
Dr. Howard D. Booth, Professor of Biology, Eastern Michigan University
AN INTEGRATED APPROACH
T H I R D E D I T I O N
Chapter 5, part A
Membrane Dynamics
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Membrane Dynamics
• Membrane Dynamics
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Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
About this Chapter
• Cell membrane structures and functions
• Membranes form fluid body compartments
• Membranes as barriers and gatekeepers
• How products move across membranes
• Distribution of water and solutes in cells & the
body
• Chemical and electrical imbalances
• Membrane permeability and changes
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Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
• Membranous tissues:
• Example: pericardial membrane
• Epithelial tissues: one to many cells thick
• Cell Membranes (plasmalemma) enclose cells
Membranes: two meanings
Figure 5-1: Membranes in the body
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Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
• Cell structure & support
• Barrier isolates cell (impermeable)
• Chemically
• Physically
• Regulates exchange (semipermeable)
• Cell communication
Cell Membranes: Overview
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Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Cell Membranes: Overview
Figure 5-2: The fluid mosaic model of the membranevisit us www.dentaltutor.in
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
• Phospholipid bilayer and cholesterol
• Membrane proteins
• Peripheral (associated)
• Integral
Membrane Structure
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Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
• Structure
• Cell polarity
• Phosphorylation
• Extracellular matrix
Structural Membrane Proteins:
Membrane-Spanning
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Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Structural Membrane Proteins:
Membrane-Spanning
Figure 5-4: The cytoskeleton is anchored to the cell membrane
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Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Structural Membrane Proteins:
Membrane-Spanning
Figure 5-5: Membrane-spanning proteins
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Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
• Membrane associated
enzymes
• External reactions
• Internal reactions
• Receptors bind
specific ligand
• Example:
Hormones
• Cell recognition
molecules
Membrane Proteins that Bind Molecules
Figure 5-6: Cell membrane receptor
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Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
• Channel proteins
• Open
• Gated
• Carrier proteins
• Bind to substrate
• Slower transport
Transporter Proteins:
Move Products Through Membrane
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Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Transporter Proteins:
Move Products Through Membrane
Figure 5-7: Transport proteins of the cell membrane
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Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Transporter Proteins:
Move Products Through Membrane
Figure 5-9: Gating of channel proteinsvisit us www.dentaltutor.in
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
• Glycolipids
• Glycoproteins
Membrane Carbohydrates:
Form External Glycocaylx
Figure 5-11: Map of cell membrane structurevisit us www.dentaltutor.in
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Membrane Proteins and Functions Reviewed
Figure 5-12: Map of membrane proteinsvisit us www.dentaltutor.in

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Membrane Dynamics

  • 1. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Dee Unglaub Silverthorn, Ph.D. HUMAN PHYSIOLOGY PowerPoint® Lecture Slide Presentation by Dr. Howard D. Booth, Professor of Biology, Eastern Michigan University AN INTEGRATED APPROACH T H I R D E D I T I O N Chapter 5, part A Membrane Dynamics
  • 2. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Membrane Dynamics • Membrane Dynamics visit us www.dentaltutor.in
  • 3. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings About this Chapter • Cell membrane structures and functions • Membranes form fluid body compartments • Membranes as barriers and gatekeepers • How products move across membranes • Distribution of water and solutes in cells & the body • Chemical and electrical imbalances • Membrane permeability and changes visit us www.dentaltutor.in
  • 4. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings • Membranous tissues: • Example: pericardial membrane • Epithelial tissues: one to many cells thick • Cell Membranes (plasmalemma) enclose cells Membranes: two meanings Figure 5-1: Membranes in the body visit us www.dentaltutor.in
  • 5. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings • Cell structure & support • Barrier isolates cell (impermeable) • Chemically • Physically • Regulates exchange (semipermeable) • Cell communication Cell Membranes: Overview visit us www.dentaltutor.in
  • 6. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Cell Membranes: Overview Figure 5-2: The fluid mosaic model of the membranevisit us www.dentaltutor.in
  • 7. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings • Phospholipid bilayer and cholesterol • Membrane proteins • Peripheral (associated) • Integral Membrane Structure visit us www.dentaltutor.in
  • 8. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings • Structure • Cell polarity • Phosphorylation • Extracellular matrix Structural Membrane Proteins: Membrane-Spanning visit us www.dentaltutor.in
  • 9. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Structural Membrane Proteins: Membrane-Spanning Figure 5-4: The cytoskeleton is anchored to the cell membrane visit us www.dentaltutor.in
  • 10. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Structural Membrane Proteins: Membrane-Spanning Figure 5-5: Membrane-spanning proteins visit us www.dentaltutor.in
  • 11. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings • Membrane associated enzymes • External reactions • Internal reactions • Receptors bind specific ligand • Example: Hormones • Cell recognition molecules Membrane Proteins that Bind Molecules Figure 5-6: Cell membrane receptor visit us www.dentaltutor.in
  • 12. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings • Channel proteins • Open • Gated • Carrier proteins • Bind to substrate • Slower transport Transporter Proteins: Move Products Through Membrane visit us www.dentaltutor.in
  • 13. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Transporter Proteins: Move Products Through Membrane Figure 5-7: Transport proteins of the cell membrane visit us www.dentaltutor.in
  • 14. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Transporter Proteins: Move Products Through Membrane Figure 5-9: Gating of channel proteinsvisit us www.dentaltutor.in
  • 15. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings • Glycolipids • Glycoproteins Membrane Carbohydrates: Form External Glycocaylx Figure 5-11: Map of cell membrane structurevisit us www.dentaltutor.in
  • 16. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Membrane Proteins and Functions Reviewed Figure 5-12: Map of membrane proteinsvisit us www.dentaltutor.in