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Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
 What is physiology?
 A review of organ systems
 Evolution and integration from cell to human
 The concept of homeostasis is introduced
 Themes in Physiology
 The science of Physiology
◦ Experimental design
◦ Data
For more Visit www.dentaltutor.in
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
 Physiology defined:
◦ Function explains why it needs to be done
◦ Mechanism explains how it does that job
 Organization of life
◦ The cell is the unit of life
◦ Cells, tissues, organs, organ systems &
organisms
For more Visit www.dentaltutor.in
Figure 1-1: Levels of organization and the related fields of study
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
 Circulatory
 Digestive
 Endocrine
 Immune
 Integumentary
 Musculoskeletal
 Nervous
 Reproductive
 Urinary
For more Visit www.dentaltutor.inFigure 1-2: The integration between systems of the body
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
 Structure and function
 Integration across
◦ Cells
◦ Tissues
◦ Organs
 Flow charts
◦ Follow process
◦ In sequence
For more Visit www.dentaltutor.in
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings For more Visit www.dentaltutor.in
Figure 1-3: Maps for physiology
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
 Cell
 Intracellular fluid
 Extracellular fluid
 Organism
◦ Protective cells
◦ Exchange cells
 External environment
 Homeostasis Defined
 Emergent properties
For more Visit www.dentaltutor.in
Figure 1-4: The internal and external environments
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
 External or internal change
 Loss of homeostasis
 Physiological attempt to correct
◦ Sensors, integrating center
◦ Response of cells & organs
For more Visit www.dentaltutor.in
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
 Successful
compensation
◦ Homeostasis reestablished
 Failure to compensate
◦ Pathophysiology
 Illness
 Death
For more Visit www.dentaltutor.inFigure 1-5: Homeostasis
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
 Homeostasis
 Structure/function
relationships
 Integration of systems
 Communication
 Membranes & exchange
 Energy
 Mass balance
 Mass flow & resistance
For more Visit www.dentaltutor.in
Figure 1-7: Mass balance in the body
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
 Observation & experimentation
◦ Hypothesis
◦ Variables
 Independent
 Dependant
◦ Controls
◦ Data
◦ Replication
◦ Theory
 Models
For more Visit www.dentaltutor.in
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
 Genetic variables
 Placebo effect
 Nocebo effect
 Ethics
For more Visit www.dentaltutor.in
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
 Crossover study
 Blind studies
 Double-blind studies
 Double-blind crossover studies
For more Visit www.dentaltutor.in
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
 Longitudinal studies
 Prospective studies
 Cross sectional studies
 Retrospective studies
 Meta-analysis
For more Visit www.dentaltutor.in
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
 X- axis
 Y- axis
 Line graph
 Bar graph
 Histogram
 Scatter plot
 Interpolation
 "Best Fit" line
For more Visit www.dentaltutor.in
Figure 1-9
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
 Organ systems
 Structures & functions
 The cell, the organism, the outside environment
 Homeostatic balancing
 Review of themes: communication, energy,
membranes, body compartments, flow and balance
 Scientific inquiry- good science
 Experimental designs
 Representing the data
For more Visit www.dentaltutor.in

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1. Introduction to physiology

  • 1. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings  What is physiology?  A review of organ systems  Evolution and integration from cell to human  The concept of homeostasis is introduced  Themes in Physiology  The science of Physiology ◦ Experimental design ◦ Data For more Visit www.dentaltutor.in
  • 2. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings  Physiology defined: ◦ Function explains why it needs to be done ◦ Mechanism explains how it does that job  Organization of life ◦ The cell is the unit of life ◦ Cells, tissues, organs, organ systems & organisms For more Visit www.dentaltutor.in Figure 1-1: Levels of organization and the related fields of study
  • 3. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings  Circulatory  Digestive  Endocrine  Immune  Integumentary  Musculoskeletal  Nervous  Reproductive  Urinary For more Visit www.dentaltutor.inFigure 1-2: The integration between systems of the body
  • 4. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings  Structure and function  Integration across ◦ Cells ◦ Tissues ◦ Organs  Flow charts ◦ Follow process ◦ In sequence For more Visit www.dentaltutor.in
  • 5. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings For more Visit www.dentaltutor.in Figure 1-3: Maps for physiology
  • 6. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings  Cell  Intracellular fluid  Extracellular fluid  Organism ◦ Protective cells ◦ Exchange cells  External environment  Homeostasis Defined  Emergent properties For more Visit www.dentaltutor.in Figure 1-4: The internal and external environments
  • 7. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings  External or internal change  Loss of homeostasis  Physiological attempt to correct ◦ Sensors, integrating center ◦ Response of cells & organs For more Visit www.dentaltutor.in
  • 8. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings  Successful compensation ◦ Homeostasis reestablished  Failure to compensate ◦ Pathophysiology  Illness  Death For more Visit www.dentaltutor.inFigure 1-5: Homeostasis
  • 9. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings  Homeostasis  Structure/function relationships  Integration of systems  Communication  Membranes & exchange  Energy  Mass balance  Mass flow & resistance For more Visit www.dentaltutor.in Figure 1-7: Mass balance in the body
  • 10. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings  Observation & experimentation ◦ Hypothesis ◦ Variables  Independent  Dependant ◦ Controls ◦ Data ◦ Replication ◦ Theory  Models For more Visit www.dentaltutor.in
  • 11. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings  Genetic variables  Placebo effect  Nocebo effect  Ethics For more Visit www.dentaltutor.in
  • 12. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings  Crossover study  Blind studies  Double-blind studies  Double-blind crossover studies For more Visit www.dentaltutor.in
  • 13. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings  Longitudinal studies  Prospective studies  Cross sectional studies  Retrospective studies  Meta-analysis For more Visit www.dentaltutor.in
  • 14. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings  X- axis  Y- axis  Line graph  Bar graph  Histogram  Scatter plot  Interpolation  "Best Fit" line For more Visit www.dentaltutor.in Figure 1-9
  • 15. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings  Organ systems  Structures & functions  The cell, the organism, the outside environment  Homeostatic balancing  Review of themes: communication, energy, membranes, body compartments, flow and balance  Scientific inquiry- good science  Experimental designs  Representing the data For more Visit www.dentaltutor.in