mapleson circuits used in anesthesia practice, are in their way out but it is as important to know the mechanism with which the gases flow to and fro through them.
anaesthesia Breathing circuits and its classification and functional analysisprateek gupta
anaesthesia breathing circuits. mapleson circuits. classification of circuits. functional analysia of circuits. draw over circuit. advantages and disadvantages of different circuits.
A breathing system is a device that conducts gases such as oxygen and anesthetic agents to the patient and conducts waste gases such as CO2 away.
Breathing systems are classified as
Open,
Semi-open,
Semi-closed
Closed.
Semi-closed systems are further divided into
Rebreathing Systems With CO2 Absorption,
Rebreathing Systems Without CO2 Absorption
Non-rebreathing Systems.
More simply, systems can be classified in two groups:
systems with CO2 washout (includes open and semi-open systems)
systems with CO2 absorption (includes closed and semi-closed systems).
anaesthesia Breathing circuits and its classification and functional analysisprateek gupta
anaesthesia breathing circuits. mapleson circuits. classification of circuits. functional analysia of circuits. draw over circuit. advantages and disadvantages of different circuits.
A breathing system is a device that conducts gases such as oxygen and anesthetic agents to the patient and conducts waste gases such as CO2 away.
Breathing systems are classified as
Open,
Semi-open,
Semi-closed
Closed.
Semi-closed systems are further divided into
Rebreathing Systems With CO2 Absorption,
Rebreathing Systems Without CO2 Absorption
Non-rebreathing Systems.
More simply, systems can be classified in two groups:
systems with CO2 washout (includes open and semi-open systems)
systems with CO2 absorption (includes closed and semi-closed systems).
Anesthesia machine and equipment -Q & A -Part II Selva Kumar
This presentation is a continuation of the same title. You can download and give transition effect to the answers, so that this presentation can be used as a quiz material.
Anesthesia machine and equipment Q & A Part -ISelva Kumar
It is a question & answer type of presentation on the anaesthetic machine and anaesthetic equipment. This presentation shall be used for conducting anaesthetic quiz for post-graduate students.
The questions asked in the Anaesthesiology viva examination are presented in this presentation which will be useful for the post-graduates appearing for the M.D-Anaesthesia examination.
Intro to Hypoxic pulmonary vasoconstriction Arun Shetty
Hypoxic pulmonary vasoconstriction, a seldom heard phenomenon but very effective physiologic property which helps lungs utilise ventilation to the maximum
Simple,inexpensive and rugged,parts are easy to dismentle and sterilize, safe to use.
Delivers the right gas mixture
Allows all methods of ventilation in all age groups
Resistence low at flows in practice
Compression and compliance loss is less.
Sturdy, small and light
Allows easy removal of waste gases
Easy to maintain with low running costs
Breathing circuits connects the patient to the anaesthesia machine through endotracheal tube or mask.
A pathway in which volatile agents and oxygen is delivered and co2 is removed.
These are divide into: Open system
Semi-closed system
Closed system
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...
Mapleson circuits
1. MAPLESON CIRCUITS
By,
Dr. Arun Kumar
Dept of Anesthesiology
Columbia Asia Referral Hospital,
Bangalore.
2.
3. DEFINITION
Circuit: a round course.
Breathing circuit: a pathway in which volatile
agents and oxygen is delivered and Co2 is
removed, 2types non-circle, circle.
Co Axial: it is where these is two coduits for
inhaled and exhaled gases, where one coduit is
inside the other.
Magills circuit: a circuit in which has reservoir
bag a corrugated tube and spring loaded
expiratory valve, rebreathing prevented by
keeping fresh gas flow more than the patients
minute respiratory volume.
4. Mapleson circuits: a circuit in which the fresh
gas flow is used to remove the exhaled Co2 .
5. ADVANTAGES/NEED
Simple, inexpensive and rugged, parts easy to
dismantle and sterilize.
Variation in minute volume affects end tidal co2
less than in circle systems.
In co axial, warm expired gas heats the
inspiratory limb.
Resistance low at flows in practice.
Lightweight, easy to position.
Compression and compliance loss less.
Change in FGF, rapid change in ins., gas
composition.
No co2 abs, possible toxic byproducts not formed.
6. HISTORY
1954 Mapleson studied and described 5 different
semiclosed anesthetic breathing systems.
These are refered as mapleson systems A-E.
Later on Willis et al, added one more system
Mapleson F.
8. MAPLESON A
Differs from other circuits, fresh gas flow is not
at the patient’s end but on the other side.
At the reservoir bag, a corrugated rubber tubing
connects the bag to the patient’s end where there
is a adjustable pressure valve.
Lacks modification: in this he has added a
expiratory limb in the tube.
makes adjusting gases easy but increases the
work of breathing.
9. MAPLESON A
technique of use:
For spontaneous breathing, the apl valve is left
open.
For controlled ventilation the valve is half closed,
so that when given positive pressure adequate
expansion of lungs is achieved.
Spontaneous respiration:
As the patient exhales, first dead space gas then
alveolar gas flows towards the bag, the same
time fresh gas flows into the bag.
When bag pressure is full APL valve opens.
10.
11. MAPLESON A
Fresh gas flow reverses the direction of exhaled
gas which vents out through the APL valve.
In the inspiration end, first gas is alveolar gas,
then dead space gas, finally fresh gas flow.
Controlled ventilation: during exhalation the
pressure in the system is low and no gas escapes
through APL valve, unless bag distends, all
exhaled gas remains in the tubing.
at inspiration most of the gases are re breathed
into the system.
13. MAPLESON B
The fresh gas inlet and APL valve is near
patient’s end.
Technique of use: for spontanoeus APL valve is
left open.
in controlled ventilation APL is closed
sufficiently to allow inflation of lungs.
Spontaneous: as Pt exhales the gas moves
through the corrugated tube with FGF, when bag
fills up, APL valve open exits exhaled gas with
little FGF. On inspiration valve closes, FGF and
gas from the tubing is taken in.
14. MAPLESON B
To prevent rebreathing FGF must be equal to
peak inspiratory flow(20-25l/min).
Controlled : similar to Mapleson A but more
efficient since FGF is near patient end.
a fresh gas flow of 2- 2.5 times minute volume is
recommended.
18. MAPLESON D
Mapleson D,E,F all have T piece at the patient
end, all function similiarly.
classic form: a length of tubing connects T
piece to the APL valve and reservoir bag next to
it.
Bain modification: fresh gas supply runs
coaxially inside the corrugated tubing, and ends
at a point where the fresh gas would have flown
if classic mapleson D was used.
The outer tubing is clear so the inner tube can be
inspected.
19. MAPLESON D
technique of use:
spontaneous: the APL valve is left open and the
gas is vented.
Assisted: the valve is partially closed, and the
bag squeezed.
Mech of use:
Spontanoeous: pt., exhaled gas chanelled back to
reservoir where it gets mixed with fresh gas flow.
FGF required is 150-200ml/kg/min. 1.5-2 times
alveolar minute volume.
Inefficient and uneconomical.
20. Controlled ventilation: efficient flow of 70-
100ml/kg/min maintains normocapnia.
Exhalation gas flows from pt to tubing, even
fresh gas enters tubing.
Inspiration: fresh gas and tubing air flows, if
FGF is low then exhaled gas may be inhaled.
Can be connected to ventilator.
23. MAPLESON E
This is used in children upto 25-30kg body
weight.
A T shaped tubing with 3 open ports, one fresh
gas, second patient end, third reservoir tubing.
Designed to provide spontaneous ventilation,
since there is almost no resistance to expiration.
Not popular as there is no scope for cotrol of gas
flows.
24. MAPLESON E
Advantage: lightweight.
minimal resistance to flow
can be used for spont/ controlled
vent.
simple design.
Disadvantage: exhaust gas not easy to scavenge.
obs to expiratory limb : high
pressure to patient.
no scope to artificially ventilate
pts.
26. MAPLESON F
It is mapleson E with a reservoir bag added at
the expiratory limb.
Hence monitoring patient’s breathing was
possible.
reservoir bag has a valve outlet at the end.
Using which for spontaneous vent can be kept
open,
While for controlled can be partially closed.
27.
28. DISADVANTAGES.
Requires high gas flows.
Due to this inspired heat and humidity tends to
be low.
In mapleson A,B,C Apl valve is in the pt’s end:
inaccessible.
In mapleson E,F difficult to scavenge.
29. REFERENCES
Dorsch, understanding of anaesthetic
equipments. Seventh edition.
Whylie, a practice of Anesthesia. Seventh edition.
Al- shaikh, Stacey, essentials of Anesthetic
equipments. Third edition.
World wide web.