This document provides an overview of the PEC I, PEC II, and serratus plane blocks. It describes the neural anatomy of the chest wall and how each block works. The PEC I blocks the lateral and medial pectoral nerves. The PEC II extends the block to also cover the T2-4 spinal nerves and long thoracic nerve. The serratus plane block covers the thoracodorsal and intercostal nerves laterally. Proper ultrasound identification of muscle planes and appropriate local anesthetic deposition are described for each block. Indications for each block depend on the extent of breast or chest wall surgery.
new technique for pain management ,described by dr forero ,it can replace epidural anesthesia,paravertebral anesthesia and other regional blocks.it can be used for both acute and chronic painful conditions
new technique for pain management ,described by dr forero ,it can replace epidural anesthesia,paravertebral anesthesia and other regional blocks.it can be used for both acute and chronic painful conditions
Regional Blocks of the Upper Limb and Thorax RRTRanjith Thampi
Blocks of the UL and Thorax made easy. Most methods mentioned here are modifications and not classical methods used that maybe be required for examination writing purpose.
Osseous anatomy, Types of approaches(Position,landmarks,Incision,Superficial and Deep surgical dissection) , structures at risk, Extensile approaches with diagrams and eponymous .
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
1. PEC I AND PEC II, SERRATUS
PLANE BLOCK- A REFRESHER
BY,
DR. ARUN KUMAR
DEPT OF ANESTHESIOLOGY
COLUMBIA ASIA HOSPITAL, YSH.
BANGALORE.
2. Why pecs/ serratus anterior block
• Paravertebral block was the most widely used
technique of RA for breast surgeries.
• However there is a risk of pneumothorax,
inadvertant entry of needle into the vertebral
canal, with consequent spinal cord trauma.
• Also it did not provide complete analgesia to the
anterior chest wall, since the innervation was not
exclusive to thoracic spinal nerves, but also
brachial plexus, via medial and lateral pectoral
nerves
3. • They all rely on placing LA between the
thoracic muscles.
• Like the TAP block is to the abdomen,
practitioners have likened these blocks to the
thorax
• It is facilitated in this era with the advent of
the widespread availability of the ultrasound.
4. ANATOMY
• Muscles relevant for the thoracic blocks are
pectoralis major, pectoralis minor, serratus
anterior, latissimus dorsi and the intercostal
muscles.
5.
6. Neural innervation- ant. Chest wall
1. Pectoral nerves - from the brachial plexus cords:
a. Lateral pectoral nerve - from C5-7, runs between pectoralis major and minor to
supply supply pectoralis major.
b. Medial pectoral nerve - from C8-T1, runs deep to pectoralis minor to supply
pectoralis major and minor.
2. T2-6 spinal nerves - run in a plane between the intercostal muscles and give off
lateral and anterior branches :
a. Lateral – pierces the intercostal muscles/serratus anterior in the mid axillary line
to give off anterior and posterior cutaneous branches.
b. Anterior – pierces the intercostal muscles and serratus anterior anteriorly to
supply the medial breast.
3. Long thoracic nerve and thoracodorsal nerve:
a. Long thoracic nerve – from C5-7, runs on outer surface of serratus anterior to
the axilla where it supplies serratus anterior.
b. Thoracodorsal nerve – from C6-8 via the posterior cord, runs deep in the
posterior axillary wall to supply latissimus dorsi.
9. • Depending on the extent of surgery, the regional
techniques are chosen.
• PEC 1: LA injection between pectoralis major and minor at the 3rd rib level
to block the lateral and medial pectoral nerves. Appropriate for surgery limited
to pectoralis major.
• PEC 2: a PECS 1 block, in addition a LA injection between pectoralis
minor and serratus anterior at the 3rd rib level. By The latter injection
blocks the lateral branch of the T2-4 spinal nerves, and possibly the
anterior branch if sufficient LA penetrates the external intercostal
muscles. By entering the axilla, the long thoracic nerve may also be
blocked . Suitable for more extensive excisions e.g. tumour resections,
mastectomy, axillary clearance.
10. • SA: A single LA injection between latissimus dorsi
and serratus anterior at the 5th rib level in the mid
axillary line. This injection blocks the thoracodorsal
nerve. Suitable for latissimus dorsi flap
reconstruction, multiple rib fractures.
• The ideal position: supine patient, arms abducted,
high frequency linear probe. With in plane technique
from medial to lateral(or posterior) needle direction.
11.
12.
13. PECS “ THE ORIGINAL” BLOCK
• Lateral and medial pectoral nerves blocked.
• Indications: surgeries involving pecs major muscle. (breast expanders,
traumatic chest injuries, portocath, pacemaker insertion).
• LA: 10ml of the solution, to be deposited between pec major and minor at the
3rd rib level.
• Technique – with the probe at the mid clavicular level and angled
inferolaterally, first locate the axillary artery and vein. Next move the probe
laterally until pectoralis minor and serratus anterior are identified. Locate the
2nd rib immediately under the axillary artery, then count the 3rd rib, and with
further lateral probe movement, the 4th rib.
• With the image centered at the level of the 3rd rib, advance the needle in-
plane from medial to lateral in an oblique manner until the tip lies between
pectoralis major and minor. Inject 10 mL LA between pectoralis major and
minor.
14.
15. PECS II “ MODIFIED” BLOCK
• Nerves blocked– T2-4 spinal nerves (including intercostobrachial nerve) and
long thoracic nerve.
• Indications (more extensive breast surgery involving serratus anterior and the
axilla) tumour resection, sentinel node excision, axillary clearence, tissue
expanders.
• LA deposition – 20 mL LA injection between pectoralis minor (laterally) and
serratus anterior at the 3rd rib level (this injection aims to enter the axilla to
reach the target nerves, but LA will only enter the axilla if the fascia on the
pectoralis minor lateral border is breached by surgery).
• Technique – Perform sonography as for PECS 1 , but also identify the potential
space between the lateral extent of pectoralis minor and serratus anterior.
First perform a PECS 1 injection between pectoralis major and minor, then a
second 20 mL injection between pectoralis minor and serratus anterior .
•
19. SERRATUS PLANE BLOCK
• Nerve blocked: thoracodorsal , thoracic intercostal nerves. Lateral part of
the thorax is blocked.
• Indication: latissimus dorsi flap reconstruction.
• LA: Probe in the midclavicular line in sagittal plane, to visualise the ribs
and at the 5th rib the probe oriented in the midaxillary line, latissimus
dorsi is superior and posterior, teres major superior, serratus in deep and
inferior.
• 2 planes are described for the block, superficial i.e above the muscle,
deep: below the serratus anterior.
20.
21. Area of sensory loss following superficial
(above) or deep (below) serratus plane block.
23. • Drug dilution: 0.25% or 0.125% bupivacaine/
levobupivacaine.
• As a sole anesthetic?
24. • Blanco R. The 'pecs block': a novel technique for providing analgesia after breast
surgery. Anaesthesia. 2011 Sep;66(9):847-8.
• Blanco R, et al. Ultrasound description of Pecs II (modified Pecs I): A novel
approach to breast surgery. Rev Esp Anestesiol Reanim. 2012.
• Blanco R et al, serratus plane block- a novel ultrasound guided thoracic wall nerve
block, Anesthesia 2013, 68, 11-0-1113.
• www.Ultrasoundblock.com