This document provides an overview of major muscles in the human body, describing their origins, insertions, joints crossed, and actions. It covers muscles of the lower limb including the hamstrings, quadriceps, hip flexors and extensors, and calf muscles. It also details muscles of the shoulder girdle and shoulder joint, including rotator cuff muscles. Key back muscles like the erector spinae and muscles of the anterior abdominal wall are outlined. For each muscle or muscle group, a brief description of no more than 3 sentences is given.