This document summarizes the origin, insertion, nerve innervation, functions, and clinical significance of various muscles in the anterior thigh, medial thigh, posterior thigh, gluteal region, and lateral rotators. It describes over 15 muscles including their actions at the hip and knee joints. The sartorius, rectus femoris, vastus lateralis and medialis all have the function of extending the leg at the knee joint. The adductor longus, brevis and magnus all adduct and medially rotate the thigh. The semimembranosus, semitendinosus and biceps femoris all flex the leg at the knee joint. Damage to the gluteus maximus can cause