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DIGESTION
AND
ABSORPTION
PPT
Nutrition is the science that
interprets the interaction of
nutrients and other substances in
food in relation to maintenance,
growth, reproduction, health and
disease of an organism. It includes
food intake, absorption,
assimilation,
biosynthesis,catabolism and
Basic steps of Holozoic Nutrition
Ingestion : Intake of food.
Digestion : Breaking down of complex organic
food materials into simpler, smaller soluble
molecules.
Absorption and assimilation : Absorption of
digested food into blood or lymph and its use in the
body cells for synthesis of complex components.
Egestion : Elimination of undigested food as
faeces.
Digestion
Digestion – The process of changing food
into simple components which the body
can absorb
Digestive tract or Gastrointestinal tract-
where digestion & absorption take place
Mouth->esophagus->stomach->small
intestine->large intestine
DIGESTIVE SYSTEM
ALIMENTARY
CANALThe alimentary canal begins with an anterior opening – the mouth, and it
opens out posteriorly through the anus.
Mouth leads to buccal cavity or oral cavity.
Oral cavity has teeth and muscular tongue.
Each tooth embedded in a socket of jaw bone: such attachment called
thecodont.
Diphyodont : human has two sets of teeth in their life time:
Milk teeth or deciduous teeth
Permanent teeth.
Heterodont : teeth are of unequal shape and size.
Incisor (I)
Canine (C)
Premolar (PM)
Molar (M).
The hard chewing surface of the teeth made up of enamel.
The tongue is a freely movable muscular organ attached to the
floor of the oral cavity by the frenulum.
The upper surface of tongue has small projections called
papillae, some of which bears taste buds.
The oral cavity leads into a short pharynx which serves as a
common passage for food and air.
Oesophagus and the trachea open into the pharynx.
Opening of wind pipe or trachea called glottis, and that of
oesophagus is called gullet.
The cartilaginous epiglottis prevents the entry of food into the
glottis during swallowing.
Oesophagus connects pharynx with stomach.
Opening of oesophagus is regulated by gastro-oesophageal
sphincter.
Stomach
J-shaped muscular bag that
stores the food you eat, breaks
it down into tiny pieces.
Mixes food with digestive
juices that contain enzymes to
break down proteins and
lipids.
Acid in the stomach kills
bacteria.
Food found in the stomach is
called chyme.
Small Intestine
Small intestines are
roughly 7 meters long
Lining of intestine walls
has finger-like
projections called villi, to
increase surface area.
The villi are covered in
microvilli which further
increases surface area
for absorption.
Small Intestine
Nutrients from the food pass
into the bloodstream through
the small intestine walls.
Absorbs:
80% ingested water
Vitamins
Minerals
Carbohydrates
Proteins
Lipids
•Secretes digestive enzymes
Large Intestine
About 5 feet long
Accepts what small
intestines don’t
absorb
Rectum (short term
storage which holds
feces before it is
expelled).
Large Intestine
Functions
Bacterial digestion
Ferment carbohydrates
Protein breakdown
–Absorbs more water
–Concentrate wastes
Histolology of alimentary canal :
Alimentary canal
from oesophagus to
rectum has four
layers.
Serosa.
Muscularis.
Sub mucosa.
Mucosa
Mucosa forms irregular folds (rugae) in the stomach and
small finger like folding called villi in the small intestine.
The cells lining the villi produce numerous microscopic
projections called microvilli giving a brush border
appearance. These modifications increase the surface
area for absorption. Villi are supplied with a network of
capillaries and a central lymphatic vessel called lacteal.
Epithelial cells of mucosa contain secretory cells which
secretes digestive enzymes. Mucosa also forms glands in
the stomach (gastric gland) Mucosa forms crypts in
between the bases of villi in the intestine called Crypts of
Lieberkuhn.
Small intestinal Mucosa Showing Villi
Digestive glands
The digestive glands associated with the alimentary canal
includes-
Salivary gland
Liver
Pancreas
There are three pairs of salivary gland present in the
buccal cavity.
Parotid gland (below internal ear)
Sub-maxillary / submandibular (below lower jaw)
Sub-lingual (below tongue)
All salivary glands produce saliva into the buccal cavity.
Liver
Largest gland of the body weighing about 1.2 to 1.5
kg in adult. Structural and functional unit of liver
is the hepatic lobles. Hepatic lobules consist of
hepatic cells. The bile secreted by the hepatic cells
passes through the hepatic ducts and stored in the
gall bladder in concentrated form. Bile from the
gall bladder is transported by cystic duct. Cystic
duct along with hepatic duct forms the common bile
duct. Bile duct joined with pancreatic duct to form
hepato-pancreatic duct which open into the
duodenum. Hepato-pancreatic has a swelling
portion called ampulla of Vater; the opening is
guarded by sphincter of Oddi.
Pancreas
Pancreas is a compound myxocrine gland
(both exocrine and endocrine) elongated
organ situated between the limbs of ‘U’
shaped duodenum. The exocrine aciner
cells secrete pancreatic juice containing
enzymes. The endocrine Islets of
Langerhans secrete hormones like insulin
and glucagon.
Digestive glands
(A)Salivary glands (found in mouth).
Three types are :
(i) Parotid,
(ii) Sublingual,
(iii) Submaxillary. Secrete saliva which contains
ptyalin (Salivary amylase)
(B) Pancreas : Secretes pancreatic juice.
(C) Liver : Secretes bile.
(D) Gastric glands : Secretes gastric juice.
(E) Intestinal glands : Secretes intestinal juice or
succus entericus.
DIGESTION OF FOOD
Digestion is accomplished by mechanical and chemical
process.
In the buccal cavity :
Buccal cavity performs two major functions;
Mastication of food.
Facilitation of swallowing.
The teeth and tongue with the help of saliva masticate
and mix up the food.
The saliva composed of ;
Electrolytes (Na+, K+, Cl- HCO-3)
Enzyme- salivary amylase or ptyalin.
Lysozyme.
About 30% of starch is hydrolyzed into disaccharide
(maltose) by salivary amylase in optimum pH 6.8).
Lysozyme acts as antibacterial agent preventing
infections.
Mucus in the saliva helps in lubricating and adhering
the masticated food particle into a bolus.
The bolus is then passed into oesophagus through
pharynx by swallowing or deglutition.
By peristalsis the bolus from the oesophagus passed into
the stomach.
Digestion in small intestine
Funcion of succus entericus
ABSORPTION OF DIGESTED PRODUCTS
Absorption is the process by which the end product of
digestion passes through the intestinal mucosa into the
blood or lymph.
Absorption is carried out by passive, active or
facilitated transport mechanism.
Glucose, amino acids and electrolytes are absorbed by
simple diffusion into the blood in the concentration
gradient.
Fructose and some amino acids absorbed with the help
of carrier ions like Na+. This is called facilitated diffusion.
Active transport of digested food and electrolytes takes
place against the concentration gradients.
Absorption of fatty acid and glycerol.
Fatty acids and glycerol being insoluble cannot be
absorbed into blood.
They are transported into mucosal epithelium
and triglycerides are formed.
Triglycerides are covered by a protein coat to
form small fat globules called chylomicron, which
are incorporated into the lacteal in the villi.
These lymphatic vessels ultimately release the
absorbed substances into the blood stream later on.
Assimilation and egestion
The absorbed substances finally
reach the tissues which utilize them
for their activities. This process is
calledassimilation.
The digestive wastes, solidified
into coherent faeces in the rectum
and removed to outside periodically
by the process called defaecation.
DISORDERS OF DIGESTIVE SYSTEM
Jaundice : Affected organ is the liver.
Skin and eyes turn yellow due to deposition of bile pigments.
Vomiting : Ejection of stomach contents through the mouth.
It is controlled by the vomit centre in the medulla oblongata.
A feeling of nausea precedes vomiting.
Diarrahoea : Abnormal frequency of bowel movement and
increased liquidity of the faecal discharge.
It reduces the absorption of food.
Constipation : The faeces are retained in the rectum as the
bowel movements occurs irregularly.
Indigestion : The food is not properly digested leading to a
feeling of fullness.
Digestion and absorption
Digestion and absorption

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Digestion and absorption

  • 2. Nutrition is the science that interprets the interaction of nutrients and other substances in food in relation to maintenance, growth, reproduction, health and disease of an organism. It includes food intake, absorption, assimilation, biosynthesis,catabolism and
  • 3. Basic steps of Holozoic Nutrition Ingestion : Intake of food. Digestion : Breaking down of complex organic food materials into simpler, smaller soluble molecules. Absorption and assimilation : Absorption of digested food into blood or lymph and its use in the body cells for synthesis of complex components. Egestion : Elimination of undigested food as faeces.
  • 4. Digestion Digestion – The process of changing food into simple components which the body can absorb Digestive tract or Gastrointestinal tract- where digestion & absorption take place Mouth->esophagus->stomach->small intestine->large intestine
  • 6. ALIMENTARY CANALThe alimentary canal begins with an anterior opening – the mouth, and it opens out posteriorly through the anus. Mouth leads to buccal cavity or oral cavity. Oral cavity has teeth and muscular tongue. Each tooth embedded in a socket of jaw bone: such attachment called thecodont. Diphyodont : human has two sets of teeth in their life time: Milk teeth or deciduous teeth Permanent teeth. Heterodont : teeth are of unequal shape and size. Incisor (I) Canine (C) Premolar (PM) Molar (M).
  • 7.
  • 8. The hard chewing surface of the teeth made up of enamel. The tongue is a freely movable muscular organ attached to the floor of the oral cavity by the frenulum. The upper surface of tongue has small projections called papillae, some of which bears taste buds. The oral cavity leads into a short pharynx which serves as a common passage for food and air. Oesophagus and the trachea open into the pharynx. Opening of wind pipe or trachea called glottis, and that of oesophagus is called gullet. The cartilaginous epiglottis prevents the entry of food into the glottis during swallowing. Oesophagus connects pharynx with stomach. Opening of oesophagus is regulated by gastro-oesophageal sphincter.
  • 9. Stomach J-shaped muscular bag that stores the food you eat, breaks it down into tiny pieces. Mixes food with digestive juices that contain enzymes to break down proteins and lipids. Acid in the stomach kills bacteria. Food found in the stomach is called chyme.
  • 10. Small Intestine Small intestines are roughly 7 meters long Lining of intestine walls has finger-like projections called villi, to increase surface area. The villi are covered in microvilli which further increases surface area for absorption.
  • 11.
  • 12. Small Intestine Nutrients from the food pass into the bloodstream through the small intestine walls. Absorbs: 80% ingested water Vitamins Minerals Carbohydrates Proteins Lipids •Secretes digestive enzymes
  • 13. Large Intestine About 5 feet long Accepts what small intestines don’t absorb Rectum (short term storage which holds feces before it is expelled).
  • 14. Large Intestine Functions Bacterial digestion Ferment carbohydrates Protein breakdown –Absorbs more water –Concentrate wastes
  • 15. Histolology of alimentary canal : Alimentary canal from oesophagus to rectum has four layers. Serosa. Muscularis. Sub mucosa. Mucosa
  • 16. Mucosa forms irregular folds (rugae) in the stomach and small finger like folding called villi in the small intestine. The cells lining the villi produce numerous microscopic projections called microvilli giving a brush border appearance. These modifications increase the surface area for absorption. Villi are supplied with a network of capillaries and a central lymphatic vessel called lacteal. Epithelial cells of mucosa contain secretory cells which secretes digestive enzymes. Mucosa also forms glands in the stomach (gastric gland) Mucosa forms crypts in between the bases of villi in the intestine called Crypts of Lieberkuhn.
  • 17. Small intestinal Mucosa Showing Villi
  • 18. Digestive glands The digestive glands associated with the alimentary canal includes- Salivary gland Liver Pancreas There are three pairs of salivary gland present in the buccal cavity. Parotid gland (below internal ear) Sub-maxillary / submandibular (below lower jaw) Sub-lingual (below tongue) All salivary glands produce saliva into the buccal cavity.
  • 19. Liver
  • 20. Largest gland of the body weighing about 1.2 to 1.5 kg in adult. Structural and functional unit of liver is the hepatic lobles. Hepatic lobules consist of hepatic cells. The bile secreted by the hepatic cells passes through the hepatic ducts and stored in the gall bladder in concentrated form. Bile from the gall bladder is transported by cystic duct. Cystic duct along with hepatic duct forms the common bile duct. Bile duct joined with pancreatic duct to form hepato-pancreatic duct which open into the duodenum. Hepato-pancreatic has a swelling portion called ampulla of Vater; the opening is guarded by sphincter of Oddi.
  • 22. Pancreas is a compound myxocrine gland (both exocrine and endocrine) elongated organ situated between the limbs of ‘U’ shaped duodenum. The exocrine aciner cells secrete pancreatic juice containing enzymes. The endocrine Islets of Langerhans secrete hormones like insulin and glucagon.
  • 23. Digestive glands (A)Salivary glands (found in mouth). Three types are : (i) Parotid, (ii) Sublingual, (iii) Submaxillary. Secrete saliva which contains ptyalin (Salivary amylase) (B) Pancreas : Secretes pancreatic juice. (C) Liver : Secretes bile. (D) Gastric glands : Secretes gastric juice. (E) Intestinal glands : Secretes intestinal juice or succus entericus.
  • 24. DIGESTION OF FOOD Digestion is accomplished by mechanical and chemical process. In the buccal cavity : Buccal cavity performs two major functions; Mastication of food. Facilitation of swallowing. The teeth and tongue with the help of saliva masticate and mix up the food. The saliva composed of ; Electrolytes (Na+, K+, Cl- HCO-3) Enzyme- salivary amylase or ptyalin. Lysozyme.
  • 25. About 30% of starch is hydrolyzed into disaccharide (maltose) by salivary amylase in optimum pH 6.8). Lysozyme acts as antibacterial agent preventing infections. Mucus in the saliva helps in lubricating and adhering the masticated food particle into a bolus. The bolus is then passed into oesophagus through pharynx by swallowing or deglutition. By peristalsis the bolus from the oesophagus passed into the stomach.
  • 26. Digestion in small intestine
  • 27. Funcion of succus entericus
  • 28. ABSORPTION OF DIGESTED PRODUCTS Absorption is the process by which the end product of digestion passes through the intestinal mucosa into the blood or lymph. Absorption is carried out by passive, active or facilitated transport mechanism. Glucose, amino acids and electrolytes are absorbed by simple diffusion into the blood in the concentration gradient. Fructose and some amino acids absorbed with the help of carrier ions like Na+. This is called facilitated diffusion. Active transport of digested food and electrolytes takes place against the concentration gradients.
  • 29. Absorption of fatty acid and glycerol. Fatty acids and glycerol being insoluble cannot be absorbed into blood. They are transported into mucosal epithelium and triglycerides are formed. Triglycerides are covered by a protein coat to form small fat globules called chylomicron, which are incorporated into the lacteal in the villi. These lymphatic vessels ultimately release the absorbed substances into the blood stream later on.
  • 30. Assimilation and egestion The absorbed substances finally reach the tissues which utilize them for their activities. This process is calledassimilation. The digestive wastes, solidified into coherent faeces in the rectum and removed to outside periodically by the process called defaecation.
  • 31. DISORDERS OF DIGESTIVE SYSTEM Jaundice : Affected organ is the liver. Skin and eyes turn yellow due to deposition of bile pigments. Vomiting : Ejection of stomach contents through the mouth. It is controlled by the vomit centre in the medulla oblongata. A feeling of nausea precedes vomiting. Diarrahoea : Abnormal frequency of bowel movement and increased liquidity of the faecal discharge. It reduces the absorption of food. Constipation : The faeces are retained in the rectum as the bowel movements occurs irregularly. Indigestion : The food is not properly digested leading to a feeling of fullness.