The document outlines topics that will be covered in a bioinformatics course, including biological databases, sequence alignments, database searching, phylogenetics, protein structure, gene prediction, gene ontologies, hidden Markov models, and non-coding RNA. It then provides more details on topics like using sequence similarity to gather information from unknown protein sequences, finding conserved patterns in alignments using profiles and hidden Markov models, and challenges around gene prediction from raw genomic sequences.