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Dr.R.Rajprasath,
                                Junior resident,JIPMER
19/10/2012   JIPMER   ANATOMY                            1
 DNA & structure

   Gene & Genome

   Chromosomes

   Chromatin & Chromatids

   Locus & Allele




19/10/2012     JIPMER   ANATOMY   2
 nucleic acid-stores & transmits genetic information


  Repeating sequences of nucleotides




19/10/2012     JIPMER      ANATOMY                       3
19/10/2012   JIPMER   ANATOMY   4
19/10/2012   JIPMER   ANATOMY   5
19/10/2012   JIPMER   ANATOMY   6
19/10/2012   JIPMER   ANATOMY   7
 Unit of genetic information encoded by DNA
  Organised into a number of rod shaped organelle
             called CHROMOSOMES.

  GENOME : complete sets DNA of an organism




19/10/2012         JIPMER   ANATOMY                  8
 Condensed DNA + histone+ non histone proteins


  Chromatin: uncondensed DNA+ histone+ non
        histone proteins

  Euchromatin : active
  Heterochromatin : inactive


  Chromatid : cell division- replica of chromosome


19/10/2012         JIPMER   ANATOMY                   9
19/10/2012   JIPMER   ANATOMY   10
19/10/2012   JIPMER   ANATOMY   11
 locus-precise position of gene in a chromosome




  Allele- pair of genes in same locus in homologous
        chromosomes



              homozygous     heterozygous


19/10/2012       JIPMER    ANATOMY                     12
19/10/2012   JIPMER   ANATOMY   13
19/10/2012   JIPMER   ANATOMY   14
Gene,loci,
                                       chromosome
             ??!!                      DNA,allele…




19/10/2012          JIPMER   ANATOMY                 15
Have a brake..




19/10/2012   JIPMER   ANATOMY   16

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Genetics introduction to Medicos

  • 1. Dr.R.Rajprasath, Junior resident,JIPMER 19/10/2012 JIPMER ANATOMY 1
  • 2.  DNA & structure  Gene & Genome  Chromosomes  Chromatin & Chromatids  Locus & Allele 19/10/2012 JIPMER ANATOMY 2
  • 3.  nucleic acid-stores & transmits genetic information  Repeating sequences of nucleotides 19/10/2012 JIPMER ANATOMY 3
  • 4. 19/10/2012 JIPMER ANATOMY 4
  • 5. 19/10/2012 JIPMER ANATOMY 5
  • 6. 19/10/2012 JIPMER ANATOMY 6
  • 7. 19/10/2012 JIPMER ANATOMY 7
  • 8.  Unit of genetic information encoded by DNA  Organised into a number of rod shaped organelle called CHROMOSOMES.  GENOME : complete sets DNA of an organism 19/10/2012 JIPMER ANATOMY 8
  • 9.  Condensed DNA + histone+ non histone proteins  Chromatin: uncondensed DNA+ histone+ non histone proteins  Euchromatin : active  Heterochromatin : inactive  Chromatid : cell division- replica of chromosome 19/10/2012 JIPMER ANATOMY 9
  • 10. 19/10/2012 JIPMER ANATOMY 10
  • 11. 19/10/2012 JIPMER ANATOMY 11
  • 12.  locus-precise position of gene in a chromosome  Allele- pair of genes in same locus in homologous chromosomes homozygous heterozygous 19/10/2012 JIPMER ANATOMY 12
  • 13. 19/10/2012 JIPMER ANATOMY 13
  • 14. 19/10/2012 JIPMER ANATOMY 14
  • 15. Gene,loci, chromosome ??!! DNA,allele… 19/10/2012 JIPMER ANATOMY 15
  • 16. Have a brake.. 19/10/2012 JIPMER ANATOMY 16