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Presentation on
By
D. B. Somavanshi
[Pharmaceutical
Chemistry Department ]
SVS INSTITUTE OF PHARMACY, MUNGSE
• VITAMINS- are nonenergy producing organic compounds
essential in minute amount for normal human metabolism and for
the help of body.
• Vitamins are micronutrients, which are very much essential for
growth and for metabolism.
• The importance of vitamins as drug in primarily in the prevention
and treatment of deficiency diseases.
• Vitamins are classified into two types – based on their solubility .
1]Water soluble vitamins-Vitamin ‘C’ and
Vitamin ‘B’ complex- It contains –
a) Thiamine – B1 e) Cyanocobalamin – B12
b) Riboflavin – B2 f) Folic acid
c) Niacin - B3 g) Pantothenic acid
d) Pyridoxine– B6 h) Biotin- B7
2]Fat soluble vitamins-
Vitamin A, Vitamin D, Vitamin E and Vitamin K
Water soluble vitamins
• Vitamin B Complex is group of Vitamins.
• It contains –
a) Thiamine – B1 e) Cyanocobalamin – B12
b) Riboflavin – B2 f) Folic acid
c) Niacin - B3 g) Pantothenic acid
d) Pyridoxine– B6 h) Biotin- B7
VITAMINS SOURSE FUNCTION DEFICIENCY
Vitamin –B1 -
Thiamine
Cereals like wheat,
oil seeds like
groundnut, milk,
meat, fish.
It is needed for the
activity of some of
the enzymes of
carbohydrate
metabolism.
Beri-Beri-
In this disease, the calf muscles
become tender, vomiting,
tremors, convulsions, loss of
appetite are seen.
Vitamin-B2
Riboflavin
It is present in milk,
eggs, liver, kidney
and green leafy
vegetables.
for oxidation
reduction reactions
in the cell and in
cellular respiration.
Glossitis
Mouth cracks at corners.
Photophobia-scaly skin and
watering of eyes are some of
the symptoms.
Vitamin-B3
Niacin / Nicotinic
acid/
Nicotinamide
It is present in
kidney, liver, meat,
poultry fish,
legumes and
groundnuts.
Niacin is essential
for the metabolism
of carbohydrates,
proteins and fats.
Pellagra-The symptoms are
diarrhea, dementia (loss of
memory) patches on the body
when exposed to sunlight .
Vitamin-B6
(pyridoxine)
In milk, liver, meat,
egg yolk, fish,
cereals, legumes
and vegetables.
Pyridoxine plays an
important role in
the metabolism of
amino acids.
hyper irritability, anaemia,
nausea and in children it leads
to convulsions.
VITAMINS SOURSE FUNCTION DEFICIENCY
Folic acid: It is present in liver,
meat, eggs, milk,
fruits, cereals, and
leafy vegetables over
cooking of food
destroys the folic acid
 Folic acid is
required for the
synthesis of nucleic
acids (DNA and
RNA).
 It is also required
for the
development of
blood cells in the
bone marrow.
 Its deficiency causes
anemia, diarrhoea and
decrease in the
number of leucocytes.
 Cell division in tissues
such as intestinal
mucosa is affected in
folic acid deficiency
Vitamin-B12
Cynocobala
mine
Bacteria present in the
intestine synthesize this
vitamin and supply to our
body.
Liver is the main site of
storage of vitamin B12
It plays an important
role in the metabolism
of nucleic acid of
protein synthesis.
Deficiency of this vitamin
causes pernicious anemia
that is different from other
types of anaemia.
Pantothenic
acid
The sources of
pantothenic acid are
fresh vegetables, liver,
It is required for the
metabolism of
carbohydrates,
to burning sensatio
VITAMINS SOURCE FUNCTION DEFICIENCY
Vitamin
B7-
(Biotin)
Sources: Biotin is present
in pulses, nuts, vegetables,
liver and kidney
It is required for
protein metabolism.
Deficiency
disorders: Deficiency
leads to muscle
pains, fatigue,
disorders in the
nervous system and
mental depression
Vitamin C
(Ascorbic
Acid )
Vitamin C is present in fresh
fruits, green leafy vegetables,
tomatoes and
germinating pulses.
Citrus fruit and Indian
gooseberry are the richest
source of this vitamin.
Guava is another cheap and
rich source of Vitamin C.
Vitamin C plays an
important role in tissue
oxidation reactions.
It is required for the
formation of collagen
which is required for
the formation of blood
vessels, connective
tissue, cartilage and
dentine of teeth.
Vitamin C also helps in
the absorption and
storage of iron.
This Vitamin is also
required for normal
SCURVY:
Scurvy is the nutritional
disorder caused due to
the deficiency of
Vitamin ‘C’.
The symptoms of this
disease are swelling of
gums, bleeding from
gums and from the
joints and under the
skin.
2]Fat soluble vitamins-
Vitamin A, Vitamin D, Vitamin
E and Vitamin K
Multivitamin-
• A multivitamin should contain fat‐soluble
vitamins A, D, E; water‐soluble vitamins B1,
B2, B6, B12, niacin, pantothenic acid, biotin,
folic acid , and Vitamin C.
• They will also usually have minerals such
as zinc, magnesium, copper, and calcium in
them.
9

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Vitamins

  • 1. Presentation on By D. B. Somavanshi [Pharmaceutical Chemistry Department ] SVS INSTITUTE OF PHARMACY, MUNGSE
  • 2. • VITAMINS- are nonenergy producing organic compounds essential in minute amount for normal human metabolism and for the help of body. • Vitamins are micronutrients, which are very much essential for growth and for metabolism. • The importance of vitamins as drug in primarily in the prevention and treatment of deficiency diseases. • Vitamins are classified into two types – based on their solubility . 1]Water soluble vitamins-Vitamin ‘C’ and Vitamin ‘B’ complex- It contains – a) Thiamine – B1 e) Cyanocobalamin – B12 b) Riboflavin – B2 f) Folic acid c) Niacin - B3 g) Pantothenic acid d) Pyridoxine– B6 h) Biotin- B7 2]Fat soluble vitamins- Vitamin A, Vitamin D, Vitamin E and Vitamin K
  • 3. Water soluble vitamins • Vitamin B Complex is group of Vitamins. • It contains – a) Thiamine – B1 e) Cyanocobalamin – B12 b) Riboflavin – B2 f) Folic acid c) Niacin - B3 g) Pantothenic acid d) Pyridoxine– B6 h) Biotin- B7
  • 4. VITAMINS SOURSE FUNCTION DEFICIENCY Vitamin –B1 - Thiamine Cereals like wheat, oil seeds like groundnut, milk, meat, fish. It is needed for the activity of some of the enzymes of carbohydrate metabolism. Beri-Beri- In this disease, the calf muscles become tender, vomiting, tremors, convulsions, loss of appetite are seen. Vitamin-B2 Riboflavin It is present in milk, eggs, liver, kidney and green leafy vegetables. for oxidation reduction reactions in the cell and in cellular respiration. Glossitis Mouth cracks at corners. Photophobia-scaly skin and watering of eyes are some of the symptoms. Vitamin-B3 Niacin / Nicotinic acid/ Nicotinamide It is present in kidney, liver, meat, poultry fish, legumes and groundnuts. Niacin is essential for the metabolism of carbohydrates, proteins and fats. Pellagra-The symptoms are diarrhea, dementia (loss of memory) patches on the body when exposed to sunlight . Vitamin-B6 (pyridoxine) In milk, liver, meat, egg yolk, fish, cereals, legumes and vegetables. Pyridoxine plays an important role in the metabolism of amino acids. hyper irritability, anaemia, nausea and in children it leads to convulsions.
  • 5. VITAMINS SOURSE FUNCTION DEFICIENCY Folic acid: It is present in liver, meat, eggs, milk, fruits, cereals, and leafy vegetables over cooking of food destroys the folic acid  Folic acid is required for the synthesis of nucleic acids (DNA and RNA).  It is also required for the development of blood cells in the bone marrow.  Its deficiency causes anemia, diarrhoea and decrease in the number of leucocytes.  Cell division in tissues such as intestinal mucosa is affected in folic acid deficiency Vitamin-B12 Cynocobala mine Bacteria present in the intestine synthesize this vitamin and supply to our body. Liver is the main site of storage of vitamin B12 It plays an important role in the metabolism of nucleic acid of protein synthesis. Deficiency of this vitamin causes pernicious anemia that is different from other types of anaemia. Pantothenic acid The sources of pantothenic acid are fresh vegetables, liver, It is required for the metabolism of carbohydrates, to burning sensatio
  • 6. VITAMINS SOURCE FUNCTION DEFICIENCY Vitamin B7- (Biotin) Sources: Biotin is present in pulses, nuts, vegetables, liver and kidney It is required for protein metabolism. Deficiency disorders: Deficiency leads to muscle pains, fatigue, disorders in the nervous system and mental depression Vitamin C (Ascorbic Acid ) Vitamin C is present in fresh fruits, green leafy vegetables, tomatoes and germinating pulses. Citrus fruit and Indian gooseberry are the richest source of this vitamin. Guava is another cheap and rich source of Vitamin C. Vitamin C plays an important role in tissue oxidation reactions. It is required for the formation of collagen which is required for the formation of blood vessels, connective tissue, cartilage and dentine of teeth. Vitamin C also helps in the absorption and storage of iron. This Vitamin is also required for normal SCURVY: Scurvy is the nutritional disorder caused due to the deficiency of Vitamin ‘C’. The symptoms of this disease are swelling of gums, bleeding from gums and from the joints and under the skin.
  • 7. 2]Fat soluble vitamins- Vitamin A, Vitamin D, Vitamin E and Vitamin K
  • 8. Multivitamin- • A multivitamin should contain fat‐soluble vitamins A, D, E; water‐soluble vitamins B1, B2, B6, B12, niacin, pantothenic acid, biotin, folic acid , and Vitamin C. • They will also usually have minerals such as zinc, magnesium, copper, and calcium in them.
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