Vitamin d presentation

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  • Thanks to these studies and national headlines praising its apparent cancer-fighting properties it appears many people now consider vitamin d their wonder drug and are rushing to labs to have their levels tested.

    The patients requesting these tests through their physicains represent an increasingly health conscious-public. These patients want greater control over managing their own health, they have greater access to information related to health promotion and illness prevention, and there are a growing number of media stores that address their demand for news and information about personal health issues. Spikes are often seen when these three drivers come together – as in the case of vitamin d


    There is no count on how many people get their vitamin d checked. But at testing giant LabCorp, the volume of vitamin D tests doctors order has, on average, doubled every year for the past four. So far this year, test orders are up another 90%. At competitor Quest Diagnostics, the volume of D tests approximately tripled between may 2006 and last may.


    http://www.virginiahopkinstestkits.com/vitamindtest.html
    http://abcnews.go.com/video/playerIndex?id=5563319 Vitamin D video
  • Vitamin d presentation

    1. 1. Vitamin D Spikes in testing and miracle cures PFC Eaker
    2. 2. What is Vitamin D? • Fat Soluble Vitamin • Found in food • Absorbed through sunlight exposure • Converted to hormone form through liver and kidney
    3. 3. Two Major Forms of Vitamin D • Vitamin D2, ergocalciferol • Vitamin D3, cholecalciferol
    4. 4. Other Forms of Vitamin D • Vitamin D1: molecular compound of ergocalciferol with lumisterol, 1:1 • Vitamin D4: 22-dihydroergocalciferol • Vitamin D5: sitocalciferol (made from 7- dehydrosisterol)
    5. 5. What are the sources? • Cod Liver Oil, 1 Tbs: 1,360 IU • Salmon, cooked, 3 1/2 oz: 360 IU • Mackerel, cooked, 3 1/2 oz: 345 IU • Sardines, canned in oil, drained, 3 1/2 oz: 270 IU • Milk, nonfat, reduced fat, and whole, vitamin D fortified, 1 c: 98 IU • Margarine, fortified, 1 Tbs: 60 IU • Pudding, 1/2 c prepared from mix and made with vitamin D fortified milk: 50 IU • Dry cereal, Vitamin D fortified w/10% of the recommended daily value, 3/4 c: 40-50 IU (other cereals may be fortified with more or less vitamin D) • Liver, beef, cooked, 3 1/2 oz: 30 IU • Egg, 1 whole (vitamin D is present in the yolk): 25 IU
    6. 6. Exposure to sunlight • Important source of vitamin D • Season, latitude, time of day
    7. 7. What does Vitamin D do? • Maintain normal blood levels of Calcium and Phosphorus • Aids in absorption of calcium • Promotes bone mineralization • Prevents rickets in children and Osteomalacia in adults
    8. 8. Role in immunomodulation • Binds to nuclear Vitamin D receptors (VDR) • Immune enhancing and immunosuppressive effects • Increase activity of NKCs • Increased production of cathelicidin • Therepeutic Clinical Applications
    9. 9. How much Vitamin D do we need? • Ages 19-50: 200 International Units (IU) • Ages 51-69: 400 IU • Age 70 and older: 600 IU
    10. 10. When can vitamin D deficiency occur? • Rickets • Osteomalacia
    11. 11. Rickets/Osteomalacia
    12. 12. Who may need extra vitamin D to prevent a deficiency? • Older Americans (greater than age 50) • individuals with limited sun exposure • occupations that prevent exposure to sunlight • reduced ability to absorb dietary fat • exclusively breast-fed infants
    13. 13. What is the health risk of too much vitamin D? • nausea • vomiting • poor appetite • constipation • weakness • weight loss
    14. 14. When is it ordered? • 25 OH Vitamin D test • 1,25 di OH Vitamin D test
    15. 15. Testing
    16. 16. Testing
    17. 17. Testing
    18. 18. Testing
    19. 19. Testing
    20. 20. Testing
    21. 21. Testing
    22. 22. Testing
    23. 23. Testing
    24. 24. Testing
    25. 25. Testing
    26. 26. Testing
    27. 27. Testing
    28. 28. Testing
    29. 29. Testing
    30. 30. What does the test result mean? • 25 OH Vitamin D test Low blood levels = not getting enough exposure to sunlight problem with absorption from the intestines High levels = supplementation from vitamin pills or other nutritional supplements • 1,25 di OH Vitamin D test Low levels = kidney disease one of the earliest changes to occur in persons with early kidney failure. High levels = excess parathryoid hormone diseases such as sarcoidosis or some lymphomas, that can make 1,25 di OH Vitamin D outside of the kidneys
    31. 31. Spike in Vitamin D testing • ABC NEWS - NEW YORK, NY, USA “Sunshine Vitamin May Cut Death Risk” • BBC NEWS - UNITED KINGDOM “Pain Linked With Low Vitamin D” • BLOOMBERG.COM “Death May Be Nearer For People Who lack Vitamin D” • BRITTANIA RADIO “Vitamin D Can Heal Tuberculosis?”
    32. 32. Current Research • Cancers • Heart Disease • Stroke • Diabetes • Depression • Muscle Weakness • Birth Defects • Obesity
    33. 33. Role in cancer prevention and recovery • Calcitriol – Induces death of cancer cells • Regulates Cell growth, Differentiation etc. • Daily intake of 1,000IU/day reduces risks
    34. 34. Vitamin D and Obesity • Seasons • Altitude • Calcium • Link between other diseases • Treatable
    35. 35. Vitamin D and Diabetes • Low serum levels at greater risk • Lack of Vitamin D interferes with insulin secretion
    36. 36. Vitamin D and depression • SAD • 130 patients • 600 or 4,000 IU supplements • Re-evaluated 1 year later
    37. 37. Conclusion • Vitamin D – The wonder drug? • LabCorp – Testing volume doubled every ear for the past four years • Quest Diagnostics – Testing volume tripled between May 2006 and May 2008
    38. 38. Questions?

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