VITAMIN B 2 RIBIFLAVIN

1. Vitamin B2
Riboflavin
Dr. Muhammad Sarfraz
M.B.B.S., M.Phil.(Pharmacology)
Senior Demonstrator
Quaid-e-Azam Medical College Bahawalpur, pakistan.

2. Vitamin B2
Riboflavin
2

3. Natural Sources
MILK
CHEESE
EGG WHITE
LIVER.
LEAFY GREEN VEGETABLES
ALMONDS
SOYBEANS
YEAST
3

4. 4

5. 5

6. Required Daily Amount
1.5 mg/day
6

7. Absorbed in small
intestine and distributed
to all tissues by
circulation.

8. Role of Vitamin B2
ACTIVE FORMS:
• Riboflavin-Mononucleotide
(FMN).
• Riboflavin-Adenine Dinucleotide
(FAD).
8

9. FMN
FAD

10. Active forms of riboflavin are FMN and
FAD.
They act as prosthetic groups of
several enzymes.
Catalyzes oxidation-reduction
reactions.
Growth, repair, development of
body tissues - healthy skin,
eyes and tongue

11. Role of Vitamin B2
The Active Forms Work As
Co-enzymes For About
→ 150 ←
Oxidation - Reduction Reactions
11

12. Role of Vitamin B2
Involved In
• Carbohydrate, Proteins And Fat
Metabolism
• Activation Of Vitamin B12 And
Folate.
• Protection Of Erythrocytes And
Other Cells From Oxidative Stress.
12

13. 13

14. Absorption
• Riboflavin Is Absorbed In The Proximal Intestine
• Riboflavin Is Stored
In
Liver, Kidney and Heart
As
FAD
(70- 90%)
Or
FMN Or
Riboflavin
14

15. Causes of Riboflavin Deficiency
Not Getting Enough Of The Vitamin
From The Diet.
A Result Of Conditions That Affect
Absorption In The Intestine.
15

16. Causes of Riboflavin Deficiency
The Body Not Being Able To Use The
Vitamin.
An Increase In The Excretion Of The
Vitamin From The Body.
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17. Deficiency symptoms
17

18. 18
Oral
•Angular
Stomatitis
•Cheilosis
•Glossitis

19. 19
Facial •Dermatitis Of
Nasolabial
Region.

20. 20
Ocular •Vascularization Of
Cornea

21. Deficiency symptoms
• Angular Cheilitis
(Fissuring At The Corners Of The
Mouth)
Cracked And Red Lips.
• Glossitis
Inflammation Of The Lining Of
Mouth And Tongue
21

22. Deficiency symptoms
• Mouth Ulcers
DryAnd Scaling Skin
 Seborrheic Dermatitis
The Eyes Become
Bloodshot
Itchy
Sensitive To Bright Light 22

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