The citric acid cycle occurs in the mitochondrion matrix. A two-carbon acetyl CoA molecule joins with a four-carbon compound to form citric acid, a six-carbon compound. Citric acid is converted back to the four-carbon compound, releasing carbon dioxide and hydrogen, which joins with NAD to form NADH2. NADH2 transfers hydrogen through the electron transport chain, producing ATP through oxidative phosphorylation. The cycle continuously converts nutrients into energy in the form of ATP.

1.  Made by kush sehgal
xi science
r.no -29

2.  Occurs in the matrix of the mitochondrion
 Aerobic phase (requires oxygen)
 2-carbon acetyl CoA joins with a 4-carbon
compound to form a 6- carbon compound
called Citric acid

3.  Citric acid (6C) is gradually converted back to the 4-
carbon compound
-ready to start the cycle once more
 The carbons removed are released as CO2
-enzymes controlling this process called
decarboxylases
 The hydrogens, which are removed, join with NAD
to form NADH2
-enzymes controlling the release of hydrogen are
called dehydrogenases

5.  6 points along pathway where hydrogen is
released and temporarily bound to NAD
 Reduced coenzyme NADH2 transfers hydrogen
to a chain of hydrogen carriers called
cytochrome system
 These systems are attached to the cristate of
every mitochondrion

6.  Transfer of hydrogen from each NADH2 along
system
-produces 3 ATP
-process called oxidative
phosphor ylation
 Complete oxidation of glucose yields 38
ATP
-2 during glycolysis
-36 during oxidative phosphorylation

7.  Transfer of hydrogen from each NADH2 along
system
-produces 3 ATP
-process called oxidative
phosphor ylation
 Complete oxidation of glucose yields 38
ATP
-2 during glycolysis
-36 during oxidative phosphorylation