The kidneys are paired organs located retroperitoneally that are responsible for filtering blood and regulating fluid and electrolyte balance. The kidneys contain nephrons, which are the functional filtering units. Blood enters nephrons via the glomerulus and is filtered, and the filtrate undergoes reabsorption and secretion as it passes through the renal tubules. Urine is formed and collects in the renal pelvis before exiting through the ureters. Kidney function can be assessed through urinalysis and measurements of substances such as creatinine, BUN, and inulin clearance.