The document discusses two recent studies on motor neuron disease and colon cancer. The motor neuron disease study found a way to prevent replicated RNA sequences from leaving the cell nucleus, where they cause cell death. The colon cancer study directly visualized the dynamics of nuclear pores at the nanoscale using HS-AFM, observing deformations in the nuclear pore barrier that may contribute to cancer cell death. Both studies provide new insights into disease mechanisms and potential treatments, representing advances for medical applications. The studies increase understanding of the nucleus's role and how molecular signals pass through nuclear pores, with implications for diseases like cancer and neurodegeneration.